1. Defining the role of extracellular matrix-tumour cell crosstalk in melanoma biology and therapy.
  2. Mechanisms of altered tumour cell mechanics in metastatic disease
  3. Induction of endoplasmic reticulum stress to potentiate immunogenic cell death to improve melanoma therapy
  4. Identification of unique molecular signatures of differentially cycling tumour cell subpopulations in a 3D melanoma model
  5. Mathematical models of 4D multicellular spheroids

Student projects

  1. Defining the role of extracellular matrix-tumour cell crosstalk in melanoma biology and therapy.
  2. Mechanisms of altered tumour cell mechanics in metastatic disease
  3. Identification of unique molecular signatures of differentially cycling tumour cell subpopulations in a 3D melanoma model