Book Chapters
Lappas, Martha, Leiva, Andrea, Pardo, Fabián, Sobrevía, Luis and Jawerbaum, Alicia (2014). Oxidative stress in pregnancies complicated by diabetes. Perinatal and prenatal disorders. (pp. 47-79) edited by Phyllis A. Dennery, Giuseppe Buonocore and Ola Didrik Saugstad. New York, USA: Springer. doi: 10.1007/978-1-4939-1405-0_3
Salomon, Carlos, Sobrevia, Luis, Ashman, Keith, Illanes, Sebastian E., Mitchell, Murray D. and Rice, Gregory E. (2013). The role of placental exosomes in gestational diabetes mellitus. Gestational Diabetes: Causes, Diagnosis and Treatment. (pp. 29-47) edited by Luis Sobrevia. Rijeka, Croatia: InTech. doi: 10.5772/55298
Journal Articles
Floriano, Juliana Ferreira, Barbosa, Angélica Mércia Pascon, Emanueli, Costanza, de Lima, Patrícia Rodrigues, de Oliveira, Rafael Guilen, De Carvalho, Carolina Neiva Frota, Floriano, Emerson Aparecido Ferreira, Zambuzzi, Willian Fernando, Pinto, Thaís Silva, Fernandes, Fábio Henrique, Salvadori, Daisy Maria Favero, Magalhães, Phillipe Franklin Coelho, Albano, Luiz Gustavo Simão, de Oliveira Graeff, Carlos Frederico, Sant'Ana Pegorin Brasil, Giovana, dos Santos, Lindomar Soares, Burd, Betina Sayeg, Cao, Wei, Herculano, Rondinelli Donizetti, de Assis Golim, Marjorie, Ferreira Junior, Rui Seabra, Sobrevia, Luis and Rudge, Marilza Vieira Cunha (2025). Development of a natural rubber latex-based biodevice with mesenchymal stem cells as a potential treatment for skeletal muscle regeneration in gestational diabetes-induced myopathy. International Journal of Biological Macromolecules, 289 138777, 1-14. doi: 10.1016/j.ijbiomac.2024.138777
Ferreira, Gonzalo, Cardozo, Romina, Chavarria, Luisina, Santander, Axel, Sobrevia, Luis, Chang, Wakam, Gundersen, Gregg and Nicolson, Garth L. (2025). The LINC complex in blood vessels: from physiology to pathological implications in arterioles. Journal of Physiology. doi: 10.1113/JP285906
Hill, David J., Hardy, Daniel B., Sobrevia, Luis and Desoye, Gernot (2025). Editorial: Pre-natal and post-natal environmental impacts on metabolic control. Frontiers in Endocrinology, 16 1583915, 1-2. doi: 10.3389/fendo.2025.1583915
Carrasco-Wong, Ivo, Laengst, Gernot, Sobrevia, Luis and Casanello, Paola (2024). Nrf2 pre-recruitment at Enhancer 2 is a hallmark of H2O2-induced epigenetic transcriptional memory in the HMOX1 gene in human umbilical artery endothelial cells. Journal of Cellular Physiology, 239 (11) e31243, e31243. doi: 10.1002/jcp.31243
Valero, Paola, Silva, Katherin, Valenzuela-Hinrichsen, Andres, Vasquez, Antonia, Espinoza, Fernanda, Lira, Fernanda, Cornejo, Marcelo, Fuentes, Gonzalo, Gonzalez, Daniel, Moore-Carrasco, Rodrigo, van der Beek, Eline M., Hillebrands, Jan-Luuk, van Goor, Harry, Grismaldo, Adriana and Sobrevia, Luis (2024). Shortcomings, limitations and gaps in physiological roles of extracellular vesicles in obesity. Journal of Physiology. doi: 10.1113/JP286955
Grismaldo, R. Adriana, Luevano-Martinez, Luis A., Reyes, Monserrat, Garcia-Marquez, Grecia, Garcia-Rivas, Gerardo and Sobrevia, Luis (2024). Placental mitochondrial impairment and its association with maternal metabolic dysfunction. Journal of Physiology. doi: 10.1113/JP285935
Capurro, Claudia, Sobrevia, Luis, Larocca, Maria Cecilia, Cremaschi, Graciela Alicia and Vila Petroff, Martin (2024). Health-stress-disease triangle. Pathophysiological focus and perspectives. Frontiers in Physiology, 15 1427085, 1427085. doi: 10.3389/fphys.2024.1427085
Costa, Sarah Maria Barneze, Hallur, Raghavendra Lakshmana Shetty, Reyes, David Rafael Abreu, Floriano, Juliana Ferreira, de Barros Leite Carvalhaes, Maria Antonieta, de Carvalho Nunes, Hélio Rubens, Sobrevia, Luis, Valero, Paola, Barbosa, Angélica Mércia Pascon and Rudge, Marilza Cunha Vieira (2024). Role of dietary food intake patterns, anthropometric measures, and multiple biochemical markers in the development of pregnancy-specific urinary incontinence in gestational diabetes mellitus. Nutrition, 117 112228, 112228. doi: 10.1016/j.nut.2023.112228
Diniz, Mariana S., Hiden, Ursula, Falcão-Pires, Inês, Oliveira, Paulo J., Sobrevia, Luis and Pereira, Susana P. (2023). Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: a potential threat for programming cardiovascular disease. Biochimica et Biophysica Acta. Molecular Basis of Disease, 1869 (8) 166834, 166834. doi: 10.1016/j.bbadis.2023.166834
Ferreira, Gonzalo, Santander, Axel, Cardozo, Romina, Chavarría, Luisina, Domínguez, Lucía, Mujica, Nicolás, Benítez, Milagros, Sastre, Santiago, Sobrevia, Luis and Nicolson, Garth L. (2023). Nutrigenomics of inward rectifier potassium channels. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1869 (7) 166803, 166803. doi: 10.1016/j.bbadis.2023.166803
França, Danielle Cristina Honorio, França, Eduardo Luzía, Sobrevia, Luis, Barbosa, Angélica Mércia Pascon, Honorio-França, Adenilda Cristina and Rudge, Marilza Vieira Cunha (2023). Integration of nutrigenomics, melatonin, serotonin and inflammatory cytokines in the pathophysiology of pregnancy-specific urinary incontinence in women with gestational diabetes mellitus. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1869 (6) 166737, 1-15. doi: 10.1016/j.bbadis.2023.166737
Lozano, Omar, Marcos, Patricio, Salazar-Ramirez, Felipe de Jesús, Lázaro-Alfaro, Anay F., Sobrevia, Luis and García-Rivas, Gerardo (2023). Targeting the mitochondrial Ca2+ uniporter complex in cardiovascular disease. Acta Physiologica, 237 (4) e13946, 1-25. doi: 10.1111/apha.13946
Rudge, Marilza V.C., Alves, Fernanda C.B., Hallur, Raghavendra L.S., Oliveira, Rafael G., Vega, Sofia, Reyes, David R.A., Floriano, Juliana F., Prudencio, Caroline B., Garcia, Gabriela A., Reis, Fabiana V.D.S., Emanueli, Costanza, Fuentes, Gonzalo, Cornejo, Marcelo, Toledo, Fernando, Valenzuela-Hinrichsen, Andrés, Guerra, Catalina, Grismaldo, Adriana, Valero, Paola, Barbosa, Angelica M.P. and Sobrevia, Luis (2023). Consequences of the exposome to gestational diabetes mellitus. Biochimica et Biophysica Acta - General Subjects, 1867 (2) 130282, 1-14. doi: 10.1016/j.bbagen.2022.130282
Valero, Paola, Cornejo, Marcelo, Fuentes, Gonzalo, Wehinger, Sergio, Toledo, Fernando, van der Beek, Eline M., Sobrevia, Luis and Moore-Carrasco, Rodrigo (2023). Platelets and endothelial dysfunction in gestational diabetes mellitus. Acta Physiologica, 237 (4) e13940, 1-15. doi: 10.1111/apha.13940
Carvajal, Jorge, Casanello, Paola, Toso, Alberto, Farías, Marcelo, Carrasco-Negue, Karina, Araujo, Kenny, Valero, Paola, Fuenzalida, Javiera, Solari, Caterina and Sobrevia, Luis (2023). Functional consequences of SARS-CoV-2 infection in pregnant women, fetoplacental unit, and neonate. Biochimica et biophysica acta. Molecular basis of disease, 1869 (1) 166582, 1-15. doi: 10.1016/j.bbadis.2022.166582
Sobrevia, Luis (2023). Physiology in Central and South America and hope for better times. Journal of Physiology, 602 (2), 249-251. doi: 10.1113/JP285858
Floriano, Juliana Ferreira, Barbosa, Angélica Mércia Pascon, de Oliveira, Rafael Guilen, Vega, Sofía, Catinelli, Bruna Bologna, Garcia, Gabriela Azevedo, Reyes, David Rafael, Sobrevia, Luis, Rudge, Marilza Vieira Cunha and DIAMATER Study Group (2022). Maternal care of the whole litter improves the success rate of diabetes in pregnancy in rats. Placenta, 130, 42-45. doi: 10.1016/j.placenta.2022.11.002
Alves, Fernanda Cristina Bergamo, Oliveira, Rafael Guilen de, Reyes, David Rafael Abreu, Garcia, Gabriela Azevedo, Floriano, Juliana Ferreira, Shetty, Raghavendra Hallur Lakshmana, Mareco, Edson Assunção, Dal-Pai-Silva, Maeli, Payão, Spencer Luiz Marques, Souza, Fátima Pereira de, Witkin, Steven S., Sobrevia, Luis, Barbosa, Angélica Mércia Pascon, Rudge, Marilza Vieira Cunha and Diamater Study Group (2022). Transcriptomic Profiling of Rectus Abdominis Muscle in Women with Gestational Diabetes-Induced Myopathy: Characterization of Pathophysiology and Potential Muscle Biomarkers of Pregnancy-Specific Urinary Incontinence. International Journal of Molecular Sciences, 23 (21) 12864, 1-20. doi: 10.3390/ijms232112864
Reyes, David R. A., Barbosa, Angelica M. P., Juliana, Floriano F., Sofia, Quiroz B. C. V., Costa, Sarah M. B., Hallur, Raghavendra L. S., Enriquez, Eusebio M. A., Oliveira, Rafael G., de Souza Rossignolli, Patricia, Pedroni, Cristiane Rodrigues, Alves, Fernanda C. B., Garcia, Gabriela A., Abbade, Joelcio F., Carvalho, Carolina N. F., Sobrevia, Luis, Rudge, Marilza V. C., Calderon, Iracema I. M. P., Souza, F. P., Lehana, T., Graeff, C. F.O., Magalhães, C. G., Costa, R. A.A., Lima, S. A.M., Rodrigues, M. R.K., Felisbino, S. L., Barbosa, W. F., Campos, F. J., Bossolan, G., Corrente, J. E. ... The Diamater Study Group (2022). Viability of ex-vivo myography as a diagnostic tool for rectus abdominis muscle electrical activity collected at Cesarean section within a diamater cohort study. BioMedical Engineering Online, 21 (1) 76, 1-12. doi: 10.1186/s12938-022-01042-2
Valero, Paola, Fuentes, Gonzalo, Cornejo, Marcelo, Vega, Sofía, Grismaldo, Adriana, Pardo, Fabián, García-Rivas, Gerardo, Hillebrands, Jan-Luuk, Faas, Marijke M., Casanello, Paola, van der Beek, Eline M., van Goor, Harry and Sobrevia, Luis (2022). Exposome and foetoplacental vascular dysfunction in gestational diabetes mellitus. Molecular Aspects of Medicine, 87 101019, 1-17. doi: 10.1016/j.mam.2021.101019
Prins, Jelmer R., Schoots, Mirthe H., Wessels, Jule I., Campmans-Kuijpers, Marjo J.E., Navis, Gerjan J., van Goor, Harry, Robertson, Sarah A., van der Beek, Eline M., Sobrevia, Luis and Gordijn, Sanne J. (2022). The influence of the dietary exposome on oxidative stress in pregnancy complications. Molecular Aspects of Medicine, 87 101098, 1-12. doi: 10.1016/j.mam.2022.101098
Ferreira, Gonzalo, Santander, Axel, Chavarría, Luisina, Cardozo, Romina, Savio, Florencia, Sobrevia, Luis and Nicolson, Garth L. (2022). Functional consequences of lead and mercury exposomes in the heart. Molecular Aspects of Medicine, 87 101048, 1-17. doi: 10.1016/j.mam.2021.101048
Sobrevia, Luis (2022). Molecular aspects of exposome and metabolic diseases. Molecular Aspects of Medicine, 87 101102, 1-4. doi: 10.1016/j.mam.2022.101102
Grismaldo, Adriana, Sobrevia, Luis and Morales, Ludis (2022). Role of platelet-derived growth factor c on endothelial dysfunction in cardiovascular diseases. Biochimica et Biophysica Acta - General Subjects, 1866 (10) 130188, 1-7. doi: 10.1016/j.bbagen.2022.130188
Sobrevia, Luis, Aiello, Ernesto Alejandro and Contreras, Paola (2022). Mechanisms of Endothelial Dysfunction and Cardiovascular System Adaptation. Current Vascular Pharmacology, 20 (3), 201-204. doi: 10.2174/157016112003220825112123
Santana-Garrido, Álvaro, Reyes-Goya, Claudia, Espinosa-Martín, Pablo, Sobrevia, Luis, Beltrán, Luis M., Vázquez, Carmen M. and Mate, Alfonso (2022). Oxidative and Inflammatory Imbalance in Placenta and Kidney of sFlt1-Induced Early-Onset Preeclampsia Rat Model. Antioxidants, 11 (8) 1608, 1-22. doi: 10.3390/antiox11081608
Valero, Paola, Salas, Rodrigo, Pardo, Fabián, Cornejo, Marcelo, Fuentes, Gonzalo, Vega, Sofía, Grismaldo, Adriana, Hillebrands, Jan-Luuk, van der Beek, Eline M., van Goor, Harry and Sobrevia, Luis (2022). Glycaemia dynamics in gestational diabetes mellitus. Biochimica et Biophysica Acta - General Subjects, 1866 (7) 130134, 1-19. doi: 10.1016/j.bbagen.2022.130134
Sobrevia, Luis (2022). Glycaemia dynamics concepts before and after insulin. Biochemical Pharmacology, 201 115092, 1-13. doi: 10.1016/j.bcp.2022.115092
Catinelli, Bruna B., Rossignoli, Patrícia S., Floriano, Juliana F., Carr, Aline M., de Oliveira, Rafael G., Dos Santos, Nilton J., Úbeda, Lara C. C., Spadella, Maria Angélica, Hallur, Raghavendra L. S., Sobrevia, Luis, Felisbino, Sérgio L., Calderon, Iracema M. P., Barbosa, Angélica M. P., Rudge, Marilza V. C. and The Diamater Study Group (2022). Reversal of diabetic-induced myopathy by swimming exercise in pregnant rats: a translational intervention study. Scientific Reports, 12 (1) 7375, 1-12. doi: 10.1038/s41598-022-10801-z
Bertini, Ayleen, Gárate, Bárbara, Pardo, Fabián, Pelicand, Julie, Sobrevia, Luis, Torres, Romina, Chabert, Steren and Salas, Rodrigo (2022). Impact of Remote Monitoring Technologies for Assisting Patients With Gestational Diabetes Mellitus: A Systematic Review. Frontiers in Bioengineering and Biotechnology, 10 819697, 1-14. doi: 10.3389/fbioe.2022.819697
Marín, Reinaldo, Pujol, Flor H., Rojas, Deliana and Sobrevia, Luis (2022). SARS- CoV-2 infection and oxidative stress in early-onset preeclampsia. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1868 (3) 166321, 1-11. doi: 10.1016/j.bbadis.2021.166321
Floriano, Juliana Ferreira, Emanueli, Costanza, Vega, Sofia, Barbosa, Angélica Mércia Pascon, Oliveira, Rafael Guilen de, Floriano, Emerson Aparecido Ferreira, Graeff, Carlos Frederico de Oliveira, Abbade, Joelcio Francisco, Herculano, Rondinelli Donizete, Sobrevia, Luis, Rudge, Marilza Vieira Cunha and DIAMATER Study Group (2022). Pro-angiogenic approach for skeletal muscle regeneration. Biochimica et Biophysica Acta - General Subjects, 1866 (2) 130059, 1-18. doi: 10.1016/j.bbagen.2021.130059
Bertini, Ayleen, Salas, Rodrigo, Chabert, Steren, Sobrevia, Luis and Pardo, Fabián (2022). Using Machine Learning to Predict Complications in Pregnancy: A Systematic Review. Frontiers in Bioengineering and Biotechnology, 9 780389, 1-16. doi: 10.3389/fbioe.2021.780389
Ferreira, Gonzalo, Blasina, Fernanda, Rodríguez Rey, Marianela, Anesetti, Gabriel, Sapiro, Rosana, Chavarría, Luisina, Cardozo, Romina, Rey, Grazzia, Sobrevia, Luis and Nicolson, Garth L. (2022). Pathophysiological and molecular considerations of viral and bacterial infections during maternal-fetal and –neonatal interactions of SARS-CoV-2, Zika, and Mycoplasma infectious diseases. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1868 (1) 166285, 1-18. doi: 10.1016/j.bbadis.2021.166285
Ferreira, Gonzalo, Santander, Axel, Savio, Florencia, Guirado, Mariana, Sobrevia, Luis and Nicolson, Garth L. (2021). SARS-CoV-2, Zika viruses and mycoplasma: Structure, pathogenesis and some treatment options in these emerging viral and bacterial infectious diseases. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1867 (12) 166264, 1-30. doi: 10.1016/j.bbadis.2021.166264
Mate, Alfonso, Reyes-Goya, Claudia, Santana-Garrido, Álvaro, Sobrevia, Luis and Vázquez, Carmen M. (2021). Impact of maternal nutrition in viral infections during pregnancy. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1867 (11) 166231, 166231. doi: 10.1016/j.bbadis.2021.166231
Kalita-de Croft, Priyakshi, Sharma, Shayna, Sobrevia, Luis and Salomon, Carlos (2021). Extracellular vesicle interactions with the external and internal exposome in mediating carcinogenesis. Molecular Aspects of Medicine, 87 101039, 101039. doi: 10.1016/j.mam.2021.101039
Cornejo, Marcelo, Fuentes, Gonzalo, Valero, Paola, Vega, Sofía, Grismaldo, Adriana, Toledo, Fernando, Pardo, Fabián, Moore-Carrasco, Rodrigo, Subiabre, Mario, Casanello, Paola, Faas, Marijke M, van Goor, Harry and Sobrevia, Luis (2021). Gestational diabesity and foetoplacental vascular dysfunction. Acta Physiologica, 232 (4) e13671, e13671. doi: 10.1111/apha.13671
Cornejo, Marcelo, Mieres-Castro, Daniel, Blanco, Elías H., Beltrán, Ana R., Araya, Jorge E., Fuentes, Gonzalo, Figueroa, Manuel, Labarca, Cristian, Toledo, Fernando, Ramírez, Marco A. and Sobrevia, Luis (2021). Arsenic trioxide-increased MDCK cells proliferation requires activator protein 1-mediated increase of the sodium/proton exchanger 1 activity. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1867 (1) 165977, 165977. doi: 10.1016/j.bbadis.2020.165977
Salsoso, Rocío, Mate, Alfonso, Toledo, Fernando, Vázquez, Carmen M. and Sobrevia, Luis (2021). Insulin requires A2B adenosine receptors to modulate the L-arginine/nitric oxide signalling in the human fetoplacental vascular endothelium from late-onset preeclampsia. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1867 (1) 165993, 1-16. doi: 10.1016/j.bbadis.2020.165993
Sobrevia, Luis, Valero, Paola, Grismaldo, Adriana, Villalobos-Labra, Roberto, Pardo, Fabián, Subiabre, Mario, Armstrong, Gael, Toledo, Fernando, Vega, Sofía, Cornejo, Marcelo, Fuentes, Gonzalo and Marín, Reinaldo (2020). Mitochondrial dysfunction in the fetoplacental unit in gestational diabetes mellitus. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (12) 165948, 1-13. doi: 10.1016/j.bbadis.2020.165948
Marín, Reinaldo, Chiarello, Delia I., Abad, Cilia, Rojas, Deliana, Toledo, Fernando and Sobrevia, Luis (2020). Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (12) 165961, 1-16. doi: 10.1016/j.bbadis.2020.165961
Piculo, Fernanda, Marini, Gabriela, Vesentini, Giovana, Morceli, Glilciane, Damasceno, Débora C., Sobrevia, Luis, Barbosa, Angélica M.P. and Rudge, Marilza V.C. (2020). Pregnancy-specific urinary incontinence in women with gestational hyperglycaemia worsens the occurrence and severity of urinary incontinence and quality of life over the first year post partum. European Journal of Obstetrics and Gynecology and Reproductive Biology, 252, 336-343. doi: 10.1016/j.ejogrb.2020.06.036
Rojas, Susana, Basualto, Emerita, Valdivia, Luz, Vallejos, Natalia, Ceballos, Karen, Peña, Eduardo, Rivas, Coralia, Nualart, Francisco, Guzmán-Gutiérrez, Enrique, Escudero, Carlos, Toledo, Fernando, Sobrevia, Luis, Cid, Marcela and González, Marcelo (2020). The activity of IKCa and BKCa channels contributes to insulin-mediated NO synthesis and vascular tone regulation in human umbilical vein. Nitric Oxide - Biology and Chemistry, 99, 7-16. doi: 10.1016/j.niox.2020.03.004
Chiarello, Delia I., Abad, Cilia, Rojas, Deliana, Toledo, Fernando, Vázquez, Carmen M., Mate, Alfonso, Sobrevia, Luis and Marín, Reinaldo (2020). Oxidative stress: normal pregnancy versus preeclampsia. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165354, 165354. doi: 10.1016/j.bbadis.2018.12.005
Subiabre, Mario, Villalobos-Labra, Roberto, Silva, Luis, Fuentes, Gonzalo, Toledo, Fernando and Sobrevia, Luis (2020). Role of insulin, adenosine, and adipokine receptors in the foetoplacental vascular dysfunction in gestational diabetes mellitus. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165370, 165370. doi: 10.1016/j.bbadis.2018.12.021
Rudge, Marilza Vieira Cunha, Barbosa, Angélica Mercia Pascon, Sobrevia, Luis, Gelaleti, Rafael Bottaro, Hallur, Raghavendra Lakshmana Shetty, Marcondes, João Paulo Castro, Salvadori, Daisy Maria Fávero, Prudêncio, Caroline Baldini, Magalhães, Claudia Garcia, Costa, Roberto, Abbade, Joelcio Francisco, Corrente, José Eduardo and Calderon, Iracema de Mattos Paranhos (2020). Altered maternal metabolism during mild gestational hyperglycemia as a predictor of adverse perinatal outcomes: a comprehensive analysis. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165478, 1-15. doi: 10.1016/j.bbadis.2019.05.014
Sobrevia, Luis (2020). Membrane transporters and receptors in pregnancy metabolic complications. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165617, 1-5. doi: 10.1016/j.bbadis.2019.165617
Stolzenbach, Francisca, Valdivia, Sharin, Ojeda-Provoste, Patricia, Toledo, Fernando, Sobrevia, Luis and Kerr, Bredford (2020). DNA methylation changes in genes coding for leptin and insulin receptors during metabolic-altered pregnancies. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165465, 1-8. doi: 10.1016/j.bbadis.2019.05.001
Gutiérrez, Jaime A., Gómez, Isabel, Chiarello, Delia I., Salsoso, Rocío, Klein, Andrés D., Guzmán-Gutiérrez, Enrique, Toledo, Fernando and Sobrevia, Luis (2020). Role of proteases in dysfunctional placental vascular remodelling in preeclampsia. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165448, 1-11. doi: 10.1016/j.bbadis.2019.04.004
Mate, Alfonso, Blanca, Antonio J., Salsoso, Rocío, Toledo, Fernando, Stiefel, Pablo, Sobrevia, Luis and Vázquez, Carmen M. (2020). Response to letter to the editor by briana and malamitsi-puchner: Effects of pregnancy-induced insulin resistance on the fetus and the future development of metabolic diseases in adulthood. Current Vascular Pharmacology, 18 (4), 423-424. doi: 10.2174/157016111804200507091851
Sáez, Tamara, Toledo, Fernando and Sobrevia, Luis (2019). Impaired signalling pathways mediated by extracellular vesicles in diabesity. Molecular Aspects of Medicine, 66, 13-20. doi: 10.1016/j.mam.2018.12.001
Sobrevia, Luis and Desoye, Gernot (2019). Molecular aspects of signalling in diabesity. Molecular Aspects of Medicine, 66, 1-2. doi: 10.1016/j.mam.2019.04.003
Alarcón, Sebastián, Niechi, Ignacio, Toledo, Fernando, Sobrevia, Luis and Quezada, Claudia (2019). Glioma progression in diabesity. Molecular Aspects of Medicine, 66, 62-70. doi: 10.1016/j.mam.2019.02.002
Sáez, Tamara, de Vos, Paul, Kuipers, Jeroen, Sobrevia, Luis and Faas, Marijke M. (2019). Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high D-glucose conditions. Immunobiology, 224 (2), 325-333. doi: 10.1016/j.imbio.2019.02.004
Contreras-Duarte, Susana, Carvajal, Lorena, Fuenzalida, Bárbara, Cantin, Claudette, Sobrevia, Luis and Leiva, Andrea (2019). Maternal dyslipidaemia in pregnancy with gestational diabetes mellitus: possible impact on foetoplacental vascular function and lipoproteins in the neonatal circulation. Current Vascular Pharmacology, 17 (1), 52-71. doi: 10.2174/1570161115666171116154247
Cabalín, Carolina, Villalobos-Labra, Roberto, Toledo, Fernando and Sobrevia, Luis (2019). Involvement of A2B adenosine receptors as anti-inflammatory in gestational diabesity. Molecular Aspects of Medicine, 66, 31-39. doi: 10.1016/j.mam.2019.01.001
Pardo, Fabián, Subiabre, Mario, Fuentes, Gonzalo, Toledo, Fernando, Silva, Luis, Villalobos-Labra, Roberto and Sobrevia, Luis (2019). Altered foetoplacental vascular endothelial signalling to insulin in diabesity. Molecular Aspects of Medicine, 66, 40-48. doi: 10.1016/j.mam.2019.02.003
Silva, Luis, Plösch, Torsten, Toledo, Fernando, Faas, Marijke M. and Sobrevia, Luis (2019). Adenosine kinase and cardiovascular fetal programming in gestational diabetes mellitus. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165397, 165397. doi: 10.1016/j.bbadis.2019.01.023
Ramirez, Marco A., Beltran, Ana R., Araya, Jorge E., Cornejo, Marcelo, Toledo, Fernando, Fuentes, Gonzalo and Sobrevia, Luis (2019). Involvement of intracellular pH in vascular insulin resistance. Current Vascular Pharmacology, 17 (5), 440-446. doi: 10.2174/1570161116666180911104012
Mate, Alfonso, Blanca, Antonio J., Salsoso, Rocio, Toledo, Fernando, Stiefel, Pablo, Sobrevia, Luis and Vazquez, Carmen M. (2019). Insulin Therapy in Pregnancy Hypertensive Diseases and its Effect on the Offspring and Mother Later in Life. Current Vascular Pharmacology, 17 (5), 455-464. doi: 10.2174/1570161117666181114125109
Saez, Tamara, Toledo, Fernando and Sobrevia, Luis (2019). Extracellular Vesicles and Insulin Resistance: A Potential Interaction in Vascular Dysfunction. Current Vascular Pharmacology, 17 (5), 491-497. doi: 10.2174/1570161116666181002095745
Villalobos-Labra, Roberto, Westermeier, Francisco, Pizarro, Carolina, Sáez, Pablo J., Toledo, Fernando, Pardo, Fabián, Kusanovic, Juan P., Mardones, Francisco, Poblete, José A., Sobrevia, Luis and Farías, Marcelo (2019). Neonates from women with pregestational maternal obesity show reduced umbilical vein endothelial response to insulin. Placenta, 86, 35-44. doi: 10.1016/j.placenta.2019.07.007
Gallardo, Victoria, González, Marcelo, Toledo, Fernando and Sobrevia, Luis (2019). Role of heme oxygenase 1 and human chorionic gonadotropin in pregnancy associated diseases. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165522, 1-8. doi: 10.1016/j.bbadis.2019.07.016
Carrasco-Wong, Ivo, Moller, Alejandra, Giachini, Fernanda R., Lima, Victor V., Toledo, Fernando, Stojanova, Jana, Sobrevia, Luis and San Martín, Sebastián (2019). Placental structure in gestational diabetes mellitus. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866 (2) 165535, 1-10. doi: 10.1016/j.bbadis.2019.165535
Sobrevia, Luis (2018). Placental metabolism and disease. Placenta, 70, 60-62. doi: 10.1016/j.placenta.2018.09.001
Pardo, Fabián and Sobrevia, Luis (2018). Adenosine receptors in gestational diabetes mellitus and maternal obesity in pregnancy. Receptors, 34, 529-542. doi: 10.1007/978-3-319-90808-3_22
Villalobos-Labra, Roberto, Sáez, Pablo J., Subiabre, Mario, Silva, Luis, Toledo, Fernando, Westermeier, Francisco, Pardo, Fabián, Farías, Marcelo and Sobrevia, Luis (2018). Pre-pregnancy maternal obesity associates with endoplasmic reticulum stress in human umbilical vein endothelium. Biochimica et Biophysica Acta: General Subjects, 1864 (10), 3195-3210. doi: 10.1016/j.bbadis.2018.07.007
Subiabre, Mario, Silva, Luis, Toledo, Fernando, Paublo, Mario, López, Marcia A, Boric, Mauricio and Sobrevia, Luis (2018). Insulin therapy and its consequences for the mother, foetus, and newborn in gestational diabetes mellitus. Biochimica et Biophysica Acta, 1864 (9), 2949-2956. doi: 10.1016/j.bbadis.2018.06.005
Sáez, Tamara, de Vos, Paul, Kuipers, Jeroen, Sobrevia, Luis and Faas, Marijke M. (2018). Fetoplacental endothelial exosomes modulate high D-glucose-induced endothelial dysfunction. Placenta, 66, 26-35. doi: 10.1016/j.placenta.2018.04.010
Fuenzalida, Bárbara, Sobrevia, Bastián, Cantin, Claudette, Carvajal, Lorena, Salsoso, Rocío, Gutiérrez, Jaime, Contreras-Duarte, Susana, Sobrevia, Luis and Leiva, Andrea (2018). Maternal supraphysiological hypercholesterolemia associates with endothelial dysfunction of the placental microvasculature. Scientific Reports, 8 (1) 7690, 7690. doi: 10.1038/s41598-018-25985-6
Chiarello, Delia I., Marín, Reinaldo, Proverbio, Fulgencio, Coronado, Paula, Toledo, Fernando, Salsoso, Rocio, Gutiérrez, Jaime and Sobrevia, Luis (2018). Mechanisms of the effect of magnesium salts in preeclampsia. Placenta, 69, 134-139. doi: 10.1016/j.placenta.2018.04.011
Kerr, Bredford, Leiva, Andrea, Farías, Marcelo, Contreras-Duarte, Susana, Toledo, Fernando, Stolzenbach, Francisca, Silva, Luis and Sobrevia, Luis (2018). Foetoplacental epigenetic changes associated with maternal metabolic dysfunction. Placenta, 69, 146-152. doi: 10.1016/j.placenta.2018.04.006
Ramírez, Marco A., Morales, Jorge, Cornejo, Marcelo, Blanco, Elias H., Mancilla-Sierpe, Edgardo, Toledo, Fernando, Beltrán, Ana R. and Sobrevia, Luis (2018). Intracellular acidification reduces l-arginine transport via system y+L but not via system y+/CATs and nitric oxide synthase activity in human umbilical vein endothelial cells. Biochimica et Biophysica Acta, 1864 (4 Pt A), 1192-1202. doi: 10.1016/j.bbadis.2018.01.032
Sáez, Tamara, de Vos, Paul, Sobrevia, Luis and Faas, Marijke M (2018). Is there a role for exosomes in foetoplacental endothelial dysfunction in gestational diabetes mellitus?. Placenta, 61, 48-54. doi: 10.1016/j.placenta.2017.11.007
Villalobos-Labra, Roberto, Subiabre, Mario, Toledo, Fernando, Pardo, Fabián and Sobrevia, Luis (2018). Endoplasmic reticulum stress and development of insulin resistance in adipose, skeletal, liver, and foetoplacental tissue in diabesity. Molecular Aspects of Medicine, 66, 49-61. doi: 10.1016/j.mam.2018.11.001
Chiarello, Delia I., Salsoso, Rocío, Toledo, Fernando, Mate, Alfonso, Vázquez, Carmen M. and Sobrevia, Luis (2017). Foetoplacental communication via extracellular vesicles in normal pregnancy and preeclampsia. Molecular Aspects of Medicine, 60, 69-80. doi: 10.1016/j.mam.2017.12.002
Quezada, Claudia, Torres, Ángelo, Niechi, Ignacio, Uribe, Daniel, Duarte, Susana Contreras, Toledo, Fernando, San Martín, Rody, Gutiérrez, Jaime and Sobrevia, Luis (2017). Role of extracellular vesicles in glioma progression. Molecular Aspects of Medicine, 60, 38-51. doi: 10.1016/j.mam.2017.12.003
Pardo, Fabián, Villalobos-Labra, Roberto, Sobrevia, Bastián, Toledo, Fernando and Sobrevia, Luis (2017). Extracellular vesicles in obesity and diabetes mellitus. Molecular Aspects of Medicine, 60, 81-91. doi: 10.1016/j.mam.2017.11.010
Sáez, Tamara, Salsoso, Rocío, Leiva, Andrea, Toledo, Fernando, de Vos, Paul, Faas, Marijke and Sobrevia, Luis (2017). Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus. Biochimica et Biophysica Acta, 1864 (2), 499-508. doi: 10.1016/j.bbadis.2017.11.010
Subiabre, Mario, Silva, Luis, Villalobos-Labra, Roberto, Toledo, Fernando, Paublo, Mario, López, Marcia A, Salsoso, Rocío, Pardo, Fabián, Leiva, Andrea and Sobrevia, Luis (2017). Maternal insulin therapy does not restore foetoplacental endothelial dysfunction in gestational diabetes mellitus. Biochimica et Biophysica Acta, 1863 (11), 2987-2998. doi: 10.1016/j.bbadis.2017.07.022
Jayabalan, Nanthini, Nair, Soumyalekshmi, Nuzhat, Zarin, Rice, Gregory E., Zuniga, Felipe A., Sobrevia, Luis, Leiva, Andrea, Sanhueza, Carlos, Agustin Gutierrez, Jaime, Lappas, Martha, Freeman, Dilys Jane and Salomon, Carlos (2017). Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes. Frontiers in Endocrinology, 8 (SEP) 239, 239. doi: 10.3389/fendo.2017.00239
Villalobos-Labra, Roberto, Silva, Luis, Subiabre, Mario, Araos, Joaquín, Salsoso, Rocío, Fuenzalida, Bárbara, Sáez, Tamara, Toledo, Fernando, González, Marcelo, Quezada, Claudia, Pardo, Fabián, Chiarello, Delia I, Leiva, Andrea and Sobrevia, Luis (2017). Akt/mTOR Role in Human Foetoplacental Vascular Insulin Resistance in Diseases of Pregnancy. Journal of Diabetes Research, 2017 5947859, 1-14. doi: 10.1155/2017/5947859
Gutiérrez, Jaime, Aedo, Alejandro, Mora, Jacob, Maldonado, Jorge, Salsoso, Rocío, Toledo, Fernando, Farías, Marcelo, Pardo, Fabián, Leiva, Andrea and Sobrevia, Luis (2017). Preeclampsia associates with RECK-dependent decrease in human trophoblasts migration and invasion. Placenta, 59, 19-29. doi: 10.1016/j.placenta.2017.09.004
Sobrevia, Luis and Fredholm, Bertil B. (2017). Adenosine - from molecular mechanisms to pathophysiology. Molecular Aspects of Medicine, 55, 1-3. doi: 10.1016/j.mam.2017.06.003
Celis, Natalia, Araos, Joaquín, Sanhueza, Carlos, Toledo, Fernando, Beltran, Ana R., Pardo, Fabian, Leiva, Andrea, Ramirez, Marco A. and Sobrevia, Luis (2017). Intracellular acidification increases adenosine transport in human umbilical vein endothelial cells. Placenta, 51, 10-17. doi: 10.1016/j.placenta.2017.01.120
Uribe, Daniel, Torres, Angelo, Rocha, Jose Dellis , Niechi, Ignacio, Oyarzun, Carlos, Sobrevia, Luis, San Martin, Rody and Quezada, Claudia (2017). Multidrug resistance in glioblastoma stem-like cells: role of the hypoxic microenvironment and adenosine signaling. Molecular Aspects of Medicine, 55, 140-151. doi: 10.1016/j.mam.2017.01.009
Leiva, Andrea, Guzman-Gutierrez, Enrique, Contreras-Duarte, Susana, Fuenzalida, Barbara, Cantin, Claudette, Carvajal, Lorena, Salsoso, Rocío, Gutierrez, Jaime, Pardo, Fabian and Sobrevia, Luis (2017). Adenosine receptors: modulators of lipid availability that are controlled by lipid levels. Molecular Aspects of Medicine, 55, 26-44. doi: 10.1016/j.mam.2017.01.007
Oyarzun, Carlos, Garrido, Wallys, Alarcon, Sebastian, Yanez, Alejandro, Sobrevia, Luis, Quezada, Claudia and San Martin, Rody (2017). Adenosine contribution to normal renal physiology and chronic kidney disease. Molecular Aspects of Medicine, 55 (1-2), 75-89. doi: 10.1016/j.mam.2017.01.004
Pardo, Fabian, Villalobos-Labra, Roberto, Chiarello, Delia I., Salsoso, Rocío, Toledo, Fernando, Gutierrez, Jaime, Leiva, Andrea and Sobrevia, Luis (2017). Molecular implications of adenosine in obesity. Molecular Aspects of Medicine, 55, 90-101. doi: 10.1016/j.mam.2017.01.003
Salsoso, Rocío, Farias, Marcelo, Gutierrez, Jaime, Pardo, Fabian, Chiarello, Delia I., Toledo, Fernando, Leiva, Andrea, Mate, Alfonso, Vazquez, Carmen M. and Sobrevia, Luis (2017). Adenosine and preeclampsia. Molecular Aspects of Medicine, 55, 126-139. doi: 10.1016/j.mam.2016.12.003
Peleli, Maria, Fredholm, Bertil B., Sobrevia, Luis and Carlstrom, Mattias (2017). Pharmacological targeting of adenosine receptor signaling. Molecular Aspects of Medicine, 55 (1), 4-8. doi: 10.1016/j.mam.2016.12.002
Sanhueza, Carlos, Araos, Joaquín, Naranjo, Luciano, Toledo, Fernando, Beltran, Ana R., Ramirez, Marco A., Gutierrez, Jaime, Pardo, Fabián, Leiva, Andrea and Sobrevia, Luis (2017). Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer. BBA - Molecular Basis of Disease, 1863 (1), 81-91. doi: 10.1016/j.bbadis.2016.10.013
Sanhueza, Carlos, Araos, Joaquın, Naranjo, Luciano, Barros, Eric, Subiabre, Mario, Toledo, Fernando, Gutierrez, Jaime, Chiarello, Delia I., Pardo, Fabian, Leiva, Andrea and Sobrevia, Luis (2016). Nitric oxide and pH modulation in gynaecological cancer. Journal of Cellular and Molecular Medicine, 20 (12), 2223-2230. doi: 10.1111/jcmm.12921
Cabrera, Lissette, Saavedra, Andrea, Rojas, Susana, Cid, Marcela, Valenzuela, Cristina, Gallegos, David, Careaga, Pamela, Basualto, Emerita, Haensgen, Astrid, Pena, Eduardo, Rivas, Coralia, Carlos Vera, Juan, Gallardo, Victoria, Zuniga, Leandro, Escudero, Carlos, Sobrevia, Luis, Wareing, Mark and Gonzalez, Marcelo (2016). Insulin induces relaxation and decreases hydrogen peroxide-induced vasoconstriction in human placental vascular bed in a mechanism mediated by calcium-activated potassium channels and L-arginine/nitric sxide pathways. Frontiers in Physiology, 7 (NOV) 529. doi: 10.3389/fphys.2016.00529
Silva, Luis, Subiabre, Mario, Araos, Joaquín, Saez, Tamara, Salsoso, Rocío, Pardo, Fabian, Leiva, Andrea, San Martin, Rody, Toledo, Fernando and Sobrevia, Luis (2016). Insulin/adenosine axis linked signalling. Molecular Aspects of Medicine, 55, 45-61. doi: 10.1016/j.mam.2016.11.002
Araos, Joaquin, Silva, Luis, Salsoso, Rocio, Saez, Tamara, Barros, Eric, Toledo, Fernando, Gutierrez, Jaime, Pardo, Fabian, Leiva, Andrea, Sanhueza, Carlos and Sobrevia, Luis (2016). Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus. Placenta, 43, 47-53. doi: 10.1016/j.placenta.2016.05.003
Leiva, Andrea, Fuenzalida, Barbara, Salsoso, Rocio, Barros, Eric, Toledo, Fernando, Gutierrez, Jaime, Pardo, Fabian and Sobrevia, Luis (2016). Tetrahydrobiopterin Role in human umbilical vein endothelial dysfunction in maternal supraphysiological hypercholesterolemia. Biochimica Et Biophysica Acta-Molecular Basis of Disease, 1862 (4), 536-544. doi: 10.1016/j.bbadis.2016.01.021
Sobrevia, Luis, Salsoso, Rocio, Fuenzalida, Barbara, Barros, Eric, Toledo, Lilian, Silva, Luis, Pizarro, Carolina, Subiabre, Mario, Villalobos, Roberto, Araos, Joaquin, Toledo, Fernando, Gonzalez, Marcelo, Gutierrez, Jaime, Farias, Marcelo, Chiarello, Delia I., Pardo, Fabian and Leiva, Andrea (2016). Insulin is a key modulator of fetoplacental endothelium metabolic disturbances in gestational diabetes mellitus. Frontiers in Physiology, 7 (MAR) 119, 119. doi: 10.3389/fphys.2016.00119
Dubo, Sebastian, Gallegos, David, Cabrera, Lissette, Sobrevia, Luis, Zuniga, Leandro and Gonzalez, Marcelo (2016). Cardiovascular action of insulin in health and disease: endothelial L-arginine transport and cardiac voltage-dependent potassium channels. Frontiers in Physiology, 7 (MAR) 74, 74. doi: 10.3389/fphys.2016.00074
Sanhueza, Carlos, Araos, Joaquin, Naranjo, Luciano, Barros, Eric, Toledo, Lilian, Subiabre, Mario, Toledo, Fernando, Gutierrez, Jaime, Chiarello, Delia I., Pardo, Fabian, Leiva, Andrea and Sobrevia, Luis (2016). Are NHE1 and inducible nitric oxide synthase involved in human ovarian cancer?. Pharmacological Research, 105, 183-185. doi: 10.1016/j.phrs.2016.01.007
Leiva, Andrea, Fuenzalida, Barbara, Barros, Eric, Sobrevia, Bastian, Salsoso, Rocio, Saez, Tamara, Villalobos, Roberto, Silva, Luis, Chiarello, Indira, Toledo, Fernando, Gutierrez, Jaime, Sanhueza, Carlos, Pardo, Fabian and Sobrevia, Luis (2016). Nitric oxide is a central common metabolite in vascular dysfunction associated with diseases of human pregnancy. Current Vascular Pharmacology, 14 (3), 237-259. doi: 10.2174/1570161114666160222115158
Gutierrez, J., Droppelmann, C.A., Salsoso, R., Westermeier, F., Toledo, F., Salomon, C., Sanhueza, C., Pardo, F., Leiva, A. and Sobrevia, L. (2016). A hypothesis for the role of RECK in angiogenesis. Current Vascular Pharmacology, 14 (1), 106-115. doi: 10.2174/1570161113666151014130746
Sobrevia, Luis, Ooi, Lezanne, Ryan, Scott and Steinert, Joern R. (2016). Nitric oxide: a regulator of cellular function in health and disease. Oxidative Medicine and Cellular Longevity, 2016 (1) 9782346, 9782346-2. doi: 10.1155/2016/9782346
Riquelme, Jaime A., Westermeier, Francisco, Hall, Andrew R., Vicencio, José Miguel, Pedrozo, Zully, Ibacache, Mauricio, Fuenzalida, Bárbara, Sobrevia, Luis, Davidson, Sean M., Yellon, Derek M., Sanchez, Gina . and Lavandero,Sergio (2016). Dexmedetomidine protects the heart against ischemia-reperfusion injury by an endothelial eNOS/NO dependent mechanism. Pharmacological Research, 103, 318-327. doi: 10.1016/j.phrs.2015.11.004
Leiva, Andrea, Fuenzalida, Barbara, Westermeier, Francisco, Toledo, Fernando, Salomon, Carlos, Gutierrez, Jaime, Sanhueza, Carlos, Pardo, Fabian and Sobrevia, Luis (2016). Role for tetrahydrobiopterin in the fetoplacental endothelial dysfunction in maternal supraphysiological hypercholesterolemia. Oxidative Medicine and Cellular Longevity, 2016 (1) 5346327, 1-10. doi: 10.1155/2016/5346327
Palacios, Javier, Cifuentes, Fredi, Valderrama, Jaime A., Benites, Julio, Rios, David, Gonzalez, Constanza, Chiong, Mario, Cartes-Saavedra, Benjamin, Lafourcade, Carlos, Wyneken, Ursula, Gonzalez, Pamela, Owen, Gareth I., Pardo, Fabian, Sobrevia, Luis and Calderon, Pedro Buc (2016). Modulatory effect of 2-(4-hydroxyphenyl)amino-1,4-naphthoquinone on endothelial vasodilation in rat aorta. Oxidative Medicine and Cellular Longevity, 2016 (1) 3939540, 3939540-12. doi: 10.1155/2016/3939540
Sanhueza, C., Araos, J., Naranjo, L., Villalobos, R., Westermeier, F., Salomon, C., Beltran, A. R., Ramirez, M. A., Gutierrez, J., Pardo, F., Leiva, A. and Sobrevia, L. (2016). Modulation of intracellular pH in human ovarian cancer. Current Molecular Medicine, 16 (1), 23-32. doi: 10.2174/1566524016666151222143437
Beltran, Ana R., Carraro-Lacroix, Luciene R., Bezerra, Camila N. A., Cornejo, Marcelo, Norambuena, Katrina, Toledo, Fernando, Araos, Joaquin, Pardo, Fabian, Leiva, Andrea, Sanhueza, Carlos, Malnic, Gerhard, Sobrevia, Luis and Ramirez, Marco A. (2015). Escherichia coli heat-stable enterotoxin mediates Na+/H+ exchanger 4 inhibition involving cAMP in T-84 human intestinal epithelial cells. PloS One, 10 (12) e0146042, e0146042. doi: 10.1371/journal.pone.0146042
Guzman-Gutierrez, Enrique, Armella, Axel, Toledo, Fernando, Pardo, Fabian, Leiva, Andrea and Sobrevia, Luis (2015). Insulin requires A1 adenosine receptors expression to reverse gestational diabetes-increased L-arginine transport in human umbilical vein endothelium. Purinergic Signalling, 12 (1), 175-190. doi: 10.1007/s11302-015-9491-2
Westermeier, F., Saez, T., Arroyo, P., Toledo, F., Gutierrez, J., Sanhueza, C., Pardo, F., Leiva, A. and Sobrevia, L. (2015). Insulin receptor isoforms: An integrated view focused on gestational diabetes mellitus. Diabetes/Metabolism Research and Reviews, 32 (4), 350-365. doi: 10.1002/dmrr.2729
Cifuentes, Fredi, Palacios, Javier, Nwokocha, Chukwuemeka R., Pardo, Fabian and Sobrevia, Luis (2015). Erratum to: Synchronization in the Heart Rate and the Vasomotion in Rat Aorta: Effect of Arsenic Trioxide. Cardiovascular Toxicology, 16 (1), 89-89. doi: 10.1007/s12012-015-9340-0
Leiva, A., Salsoso, R., Saez, T., Sanhueza, C., Pardo, F. and Sobrevia, L. (2015). Cross-sectional and longitudinal lipid determination studies in pregnant women reveal an association between increased maternal LDL cholesterol concentrations and reduced human umbilical vein relaxation. Placenta, 36 (8), 895-902. doi: 10.1016/j.placenta.2015.05.012
González, Marcelo, Rojas, Susana, Avila, Pía, Cabrera, Lissette, Villalobos, Roberto, Palma, Carlos, Aguayo, Claudio, Peña, Eduardo, Gallardo, Victoria, Guzmán-Gutiérrez, Enrique, Sáez, Tamara, Salsoso, Rocío, Sanhueza, Carlos, Pardo, Fabián, Leiva, Andrea and Sobrevia, Luis (2015). Insulin reverses D-glucose-increased nitric oxide and reactive oxygen species generation in human umbilical vein endothelial cells. PL o S ONE, 10 (4) e0122398, 1-23. doi: 10.1371/journal.pone.0122398
Salsoso, R., Guzman-Gutierrez, E., Saez, T., Bugueno, K., Ramirez, M. A., Farias, M., Pardo, F., Leiva, A., Sanhueza, C., Mate, A., Vazquez, C. and Sobrevia, L. (2015). Insulin restores l-arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia. Placenta, 36 (3), 287-296. doi: 10.1016/j.placenta.2014.12.007
Sobrevia, Luis, Salsoso, Rocio, Saez, Tamara, Sanhueza, Carlos, Pardo, Fablan and Leiva, Andrea (2015). Insulin therapy and fetoplacental vascular function in gestational diabetes mellitus. Experimental Physiology, 100 (3), 231-238. doi: 10.1113/expphysiol.2014.082743
Pardo, F., Silva, L., Saez, T., Salsoso, R., Gutierrez, J., Sanhueza, C., Leiva, A. and Sobrevia, L. (2015). Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction. International Journal of Obesity, 39 (8), 1264-1273. doi: 10.1038/ijo.2015.57
Westermeier, Francisco, Salomon, Carlos, Farias, Marcelo, Arroyo, Pablo, Fuenzalida, Barbara, Saez, Tamara, Salsoso, Rocio, Sanhueza, Carlos, Guzman-Gutierrez, Enrique, Pardo, Fabian, Leiva, Andrea and Sobrevia, Luis (2015). Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium. The FASEB Journal, 29 (1), 37-49. doi: 10.1096/fj.14-254219
Saez, Pablo J, Villalobos-Labra, Roberto, Westermeier, Francisco, Sobrevia, Luis and Farias-Jofre, Marcelo (2014). Modulation of endothelial cell migration by ER stress and insulin resistance: a role during maternal obesity?. Frontiers in Pharmacology, 5 Article 189, 189. doi: 10.3389/fphar.2014.00189
Westermeier, Francisco, Saez, Pablo J., Villalobos-Labra, Roberto, Sobrevia, Luis and Farias-Jofre, Marcelo (2014). Programming of fetal insulin resistance in pregnancies with maternal obesity by ER stress and inflammation. BioMed Research International, 2014 (1) 917672, 1-13. doi: 10.1155/2014/917672
Guzman-Gutierrez, Enrique, Veas, Carlos, Leiva, Andrea, Escudero, Carlos and Sobrevia, Luis (2014). Is a low level of free thyroxine in the maternal circulation associated with altered endothelial function in gestational diabetes?. Frontiers in Pharmacology, 5 (136) 00136, 1-7. doi: 10.3389/fphar.2014.00136
Salomon, Carlos, Torres, Maria Jose, Kobayashi, Miharu, Scholz-Romero, Katherin, Sobrevia, Luis, Dobierzewska, Aneta, Illanes, Sebastian E., Mitchell, Murray D. and Rice, Gregory E. (2014). A gestational profile of placental exosomes in maternal plasma and their effects on endothelial cell migration. PLoS One, 9 (6) e98667, e98667.1-e98667.12. doi: 10.1371/journal.pone.0098667
Acurio, Jesenia, Troncoso, Felipe, Bertoglia, Patricio, Salomon, Carlos, Aguayo, Claudio, Sobrevia, Luis and Escudero, Carlos (2014). Potential role of A2B adenosine receptors on proliferation/migration of fetal endothelium derived from preeclamptic pregnancies. BioMed Research International, 2014 274507, 274507-11. doi: 10.1155/2014/274507
Salsoso, Rocío, Guzman-Gutierrez, Enrique, Arroyo, Pablo, Salomon, Carlos, Zambrano, Sonia, Victoria Ruiz-Armenta, María, Blanca, Antonio Jesús, Pardo, Fabián, Leiva, Andrea, Mate, Alfonso, Sobrevia, Luis and Vazquez, Carmen María (2014). Reduced L-carnitine transport in aortic endothelial cells from spontaneously hypertensive rats. PLoS ONE, 9 (2) e90339, e90339. doi: 10.1371/journal.pone.0090339
Sobrevia, Luis, Myatt, Leslie and Rice, Gregory (2014). Diseases of pregnancy and fetal programming: cell and molecular mechanisms. Biomed Research International, 2014 (Article ID 937050) 937050, 937050. doi: 10.1155/2014/937050
Guzman-Gutierrez, Enrique, Arroyo, Pablo, Salsoso, Rocio, Fuenzalida, Barbara, Saez, Tamara, Leiva, Andrea, Pardo, Fabian and Sobrevia, Luis (2014). Role of Insulin and Adenosine in the Human Placenta Microvascular and Macrovascular Endothelial Cell Dysfunction in Gestational Diabetes Mellitus. Microcirculation, 21 (1), 26-37. doi: 10.1111/micc.12077
Leiva, Andrea, Diez de Medina, Camila, Salsoso, Rocio, Saez, Tamara, San Martin, Sebastian, Abarzua, Fernando, Farias, Marcelo, Guzman-Gutierrez, Enrique, Pardo, Fabian and Sobrevia, Luis (2013). Maternal Hypercholesterolemia in Pregnancy Associates With Umbilical Vein Endothelial Dysfunction Role of Endothelial Nitric Oxide Synthase and Arginase II. Arteriosclerosis Thrombosis and Vascular Biology, 33 (10), 2444-2453. doi: 10.1161/ATVBAHA.113.301987
Salomon, Carlos, Ryan, Jennifer, Sobrevia, Luis, Kobayashi, Miharu, Ashman, Keith, Mitchell, Murray and Rice, Gregory E. (2013). Exosomal Signaling during Hypoxia Mediates Microvascular Endothelial Cell Migration and Vasculogenesis. Plos One, 8 (7) e68451, e68451.1-e68451.24. doi: 10.1371/journal.pone.0068451
Calligaris, Sebastian D., Lecanda, Manuel, Solis, Felipe, Ezquer, Marcelo, Gutierrez, Jaime, Brandan, Enrique, Leiva, Andrea, Sobrevia, Luis and Conget, Paulette (2013). Mice long-term high-fat diet feeding recapitulates human cardiovascular alterations: an animal model to study the early phases of diabetic cardiomyopathy. PLoS One, 8 (4) e60931, e60931.1-e60931.10. doi: 10.1371/journal.pone.0060931
Salomon, Carlos, Kobayashi, Miharu, Ashman, Keith, Sobrevia, Luis, Mitchell, Murray D. and Rice, Gregory E. (2013). Hypoxia-induced changes in the bioactivity of cytotrophoblast-derived exosomes. PLoS One, 8 (11) e79636, e79636.1-e79636.14. doi: 10.1371/journal.pone.0079636
Arroyo, Pablo, Guzmán-Gutiérrez, Enrique, Pardo, Fabián, Salomón, Carlos, Westermeier,Francisco, Salsoso, Rocío, Sáez, Tamara, Leiva, Andrea and Sobrevia, Luis (2013). Gestational diabetes mellitus and the role of adenosine in the human placental endothelium and central nervous system. Global Journal of Pathology and Microbiology, 1, 24-42. doi: 10.14205/2310-8703.2013.01.01.5
Pardo, F., Arroyo, P., Salomon, C., Westermeier, F., Salsoso, R., Saez, T., Guzman-Gutierrez, E., Leiva, A. and Sobrevia, L. (2013). Role of equilibrative adenosine transporters and adenosine receptors as modulators of the human placental endothelium in gestational diabetes mellitus. Placenta, 34 (12), 1121-1127. doi: 10.1016/j.placenta.2013.09.007
Guzman-Gutierrez, Enrique, Westermeier, Francisco, Salomon, Carlos, Gonzalez, Marcelo, Pardo, Fabian, Leiva, Andrea and Sobrevia, Luis (2012). Insulin-increased L-arginine transport requires A2A adenosine receptors activation in human umbilical vein endothelium. PLoS ONE, 7 (7) e41705, e41705.1-e41705.13. doi: 10.1371/journal.pone.0041705
Salomon, Carlos, Westermeier, Francisco, Puebla, Carlos, Arroyo, Pablo, Guzman-Gutierrez, Enrique, Pardo, Fabian, Leiva, Andrea, Casanello, Paola and Sobrevia, Luis (2012). Gestational diabetes reduces adenosine transport in human placental microvascular endothelium, an effect reversed by insulin. PLoS ONE, 7 (7) e40578, e40578.1-e40578.14. doi: 10.1371/journal.pone.0040578
Guzman-Gutierrez, Enrique, Abarzua, Fernando, Belmar, Cristian, Nien, Jyh K., Ramirez, Marco A., Arroyo, Pablo, Salomon, Carlos, Westermeier, Francisco, Puebla, Carlos, Leiva, Andrea, Casanello, Paola and Sobrevia, Luis (2011). Functional Link Between Adenosine and Insulin: A Hypothesis for Fetoplacental Vascular Endothelial Dysfunction in Gestational Diabetes. Current Vascular Pharmacology, 9 (6), 750-762. doi: 10.2174/157016111797484062
Westermeier, Francisco, Salomon, Carlos, Gonzalez, Marcelo, Puebla, Carlos, Guzman-Gutierrez, Enrique, Cifuentes, Fredi, Leiva, Andrea, Casanello, Paola and Sobrevia, Luis (2011). Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium. Diabetes, 60 (6), 1677-1687. doi: 10.2337/db11-0155
Gonzalez, Marcelo, Gallardo, Victoria, Rodriguez, Natalia, Salomon, Carlos, Westermeier, Francisco, Guzman-Gutierrez, Enrique, Abarzua, Fernando, Leiva, Andrea, Casanello, Paola and Sobrevia, Luis (2011). Insulin-stimulated L-arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation. Journal of Cellular Physiology, 226 (11), 2916-2924. doi: 10.1002/jcp.22635
Guzman-Gutierrez, E., Sandoval, C., Nova, E., Castillo, J. L., Vera, J. C., Lamperti, L., Krause, B., Salomon, C., Sepulveda, C., Aguayo, C. and Sobrevia, L. (2010). Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells. Placenta, 31 (10), 928-936. doi: 10.1016/j.placenta.2010.07.016
Conference Papers
Subiabre, Mario, Salsoso, Rocio, Villalobos-Labra, Roberto, Silva, Luis, Fuenzalida, Barbara, Lopez, Marcia, Paublo, Mario, Pardo, Fabian, Leiva, Andrea and Sobrevia, Luis (2017). Insulin therapy does not reverse gestational diabetes-associated foetoplacental endothelial dysfunction. Meeting of the International-Federation-of-Placenta-Associations (IFPA), Manchester England, Aug 30-Sep 2 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.07.267
Silva, L., Subiabre, M., Villalobos-Labra, R., Salsoso, R., Lopez, A., Paulo, M., Pardo, F., Leiva, A. and Sobrevia, L. (2017). Insulin Therapy Restores the Equilibrative Nucleoside Transporter 1 Expression in Human Umbilical Vein Endothelial Cells From Gestational Diabetes Mellitus. Meeting of the Latin-American-Society-for-Maternal-Fetal-Interaction-and-Placenta (SLIMP), Puerto Varas Chile, Apr 11-13, 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.01.109
Araos, J., Saavedra, A., Sanhueza, C., Leiva, A., Ramirez, M. A. and Sobrevia, L. (2017). Sodium/proton Exchanger Subtype 1 Regulates Intracellular Ph in Human Umbilical Vein Endothelial Cells From Gestational Diabetes Mellitus. Meeting of the Latin-American-Society-for-Maternal-Fetal-Interaction-and-Placenta (SLIMP), Puerto Varas Chile, 11-13 April 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.01.107
Gutierrez, J. A., Mora, J., Salsoso, R., Leiva, A. and Sobrevia, L. (2017). Reck expression is induced in placentas from preeclampsia and reduces migration, invasion, and endovascular remodelling of first trimester human trophoblast. Meeting of the Latin-American-Society-for-Maternal-Fetal-Interaction-and-Placenta (SLIMP), Puerto Varas Chile, Apr 11-13, 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.01.092
Nunez-Hermosilla, J., Armella, A., Hernandez, M., Gallardo, D., Gutierrez, S., Fernandez, P., Gallegos, J., Leiva, A., Gonzalez, M., Escudero, C., Sobrevia, L. and Guzman-Gutierrez, E. (2017). High D-Glucose-Increased Nitric Oxide Generation Leads to Higher Deiodinase 3 Mrna Level in Human Umbilical Vein Endothelial Cells. Meeting of the Latin-American-Society-for-Maternal-Fetal-Interaction-and-Placenta (SLIMP), Puerto Varas Chile, 11-13 April 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.01.077
Saavedra, A., Rojas, S., Haensgen, A., Cid, M., Gonzalez, M., Farias, M., Villalobos-Labra, R., Leiva, A. and Sobrevia, L. (2017). Maternal Obesity Associates with Foetoplacental Vascular Dysfunction Involving Endoplasmic Reticulum Stress and Altered Insulin Vascular Reactivity. Meeting of the Latin-American-Society-for-Maternal-Fetal-Interaction-and-Placenta (SLIMP), Puerto Varas Chile, 11-13 April 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.01.072
Chiarello, D. I., Pardo, F., Salsoso, R., Fuenzalida, B., Gutierrez, J., Leiva, A. and Sobrevia, L. (2017). Effect of Mgso(4) On Protein Expression and Exosomes Release From Human Placental Microvascular Endothelial Cells From Late-Onset Preeclampsia. Meeting of the Latin-American-Society-for-Maternal-Fetal-Interaction-and-Placenta (SLIMP), Puerto Varas Chile, 11-13 April 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.01.097
Villalobos-Labra, R., Salsoso, R., Subiabre, M., Silva, L., Farias-Jofre, M., Leiva, A. and Sobrevia, L. (2017). Endoplasmic Reticulum Stress in Human Umbilical Vein Endothelial Cells From Pre-Gestational Maternal Obesity. Meeting of the Latin-American-Society-for-Maternal-Fetal-Interaction-and-Placenta (SLIMP), Puerto Varas Chile, 11-13 April 2017. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2017.01.063
Salomon, Carlos, Sarker, Suchi, Scholz, Katherin, Jose Torres, Maria, Sobrevia, Luis, Illanes, Sebastian E., Mitchell, Murray M. and Rice, Greg E. (2014). Gestational-age variations in placenta-derived exosome bioactivity and proteomic profiling in maternal plasma during normal healthy pregnancy. 2014 SGI 61st Annual Scientific Meeting, Florence Italy, March 26-29, 2014. Thousand Oaks, United States: Sage Publications. doi: 10.1177/1933719114528275
Salomon, Carlos, Mitchell, Murray, Sobrevia, Luis, Ryan, Jenny, Ashman, Keith, Illanes, Sebastian and Rice, Greg (2013). Hypoxia Increases Exosome Releases from Placental Mesenchymal Stem Cell (pMSC) and Promotes the Migration and Angiogenesis in Human Placental Microvascular Endothelial Cell (hPMEC).. 60th Annual Scientific Meeting of the Society for Gynecologic Investigation (SGI), Orlando Fl, 20-23 March 2013. Thousand Oaks, CA United States: Sage Publications, Inc.. doi: 10.1177/1933719113482088
Salomon, Carlos, Mitchell, Murray, Sobrevia, Luis, Ryan, Jennifer, Ashman, Keith, Waswani, Kanchan and Sebastian, Illanes (2013). Hypoxia Induces Exosome Deportation from Trophoblast Cells during the First Trimester of Pregnancy and Promotes Placental Mesenchymal Stem Cell Migration (pMSC).. 60th Annual Scientific Meeting of the Society for Gynecologic Investigation (SGI), Orlando, United States, 20-23 March 2013. Thousand Oaks, CA United States: Sage Publications. doi: 10.1177/1933719113482088
Salomon, Carlos, Jose Torres, Maria, Illanes, Sebastian, Kobayashi, Miharu, Sobrevia, Luis, Ashman, Keith, Mitchell, Murray and Rice, Greg (2013). Placental cell-derived exosomes increase in maternal circulation with gestational age. Meeting of the International Federation of Placenta Associations (IFPA) 2013, Whistler, Canada, 11-14 September 2013. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2013.06.235
Salomon, Carlos, Westermeier, Francisco, Guzman-Gutierrez, Enrique, Arroyo, Pablo, Pardo, Fabian, Leiva, Andrea, Casanello, Paola, Mitchell, Murray, Rice, Gregory and Sobrevia, Luis (2012). SREBP-1c AND hCHOP-C/EBP alpha involvement in insulin modulation of hENT2 activity in human placenta microvascular endothelium from gestational diabetes. Meeting of the International-Federation-of-Placenta-Associations (IFPA), Hiroshima, Japan, 18-21 September 2012. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2012.06.016
Salomon, Carlos, Sobrevia, Luis, Mitchell, Murray and Rice, Gregory (2012). Syncytial formation reduces exosome deportation from trophoblast cells. Meeting of the International-Federation of Placenta Associations (IFPA), Hiroshima Japan, 18-21 September 2012. London, United Kingdom: Elsevier.
Guzman-Gutierrez, Enrique, Puebla, Carlos, Salomon, Carlos, Westermeier, Francisco, Leiva, Andrea, Casanello, Paola and Sobrevia, Luis (2011). Insulin Reverses Gestational Diabetes-Increased L-Arginine Transport Via A(2A) Adenosine Receptors Activation in Human Umbilical Vein Endothelium. CAMBRIDGE UNIV PRESS.
Sobrevia, L., Abarzua, F., Nien, J. K., Salomon, C., Westermeier, F., Puebla, C., Cifuentes, F., Guzman-Gutierrez, E., Leiva, A. and Casanello, P. (2011). Review: Differential placental macrovascular and microvascular endothelial dysfunction in gestational diabetes. 2010 Meeting of the International-Federation-of-Placenta-Associations (IFPA), Santiago de Chile, Chile, October 2010. London, United Kingdom: Elsevier. doi: 10.1016/j.placenta.2010.12.011
Salomon, Carlos, Westermeier, Francisco, Casanello, Paola and Sobrevia, Luis (2010). Differential Modulation of Insulin Receptor Isoforms Expression and Nos Activity by Insulin in Human Placenta Microvascular Endothelial Cells From Gestational Diabetes. International-Federation-of-Placental-Associations Meeting 2010, Santiago Chile, Oct 19-22, 2010. W B SAUNDERS CO LTD.
Guzman, E., Lamperti, L., Salomon, C., Krause, B., Sobrevia, L. and Aguayo, C. (2010). Adenosine Transport Is Mediated by Different Nucleoside Transporters in Non-Differentiated and Differentiated Human Endothelial Progenitor Cells. International-Federation-of-Placental-Associations Meeting 2010, Santiago Chile, Oct 19-22, 2010. W B SAUNDERS CO LTD.
Westermeier, F., Salomon, C., Casanello, P. and Sobrevia, L. (2010). Insulin Increased Adenosine Transport in Huvec From Gestational Diabetic Pregnancies Involve Increased Expression and Activity of Hent1. International-Federation-of-Placental-Associations Meeting 2010, Santiago Chile, Oct 19-22, 2010. W B SAUNDERS CO LTD.