Associate Professor Margaret Cummings
ATH - Associate Professor
Frazer Institute
Book Chapters
Foong, Samuel Y. F., Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2022). Future role of molecular profiling in small breast samples and personalised medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 895-915) edited by Sandra J. Shin, Yunn-Yi Chen and Paula S. Ginter. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-05532-4_23
Cummings, Margaret C., Simpson, Peter T. and Lakhani, Sunil R. (2020). Columnar cell lesions. Breast Pathology. Encyclopedia of Pathology. (pp. 71-79) edited by Anna Sapino and Janina Kulka. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-62539-3
Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalized medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 803-817) edited by Sandra J. Shin. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-26291-8
Sim, Sarah Yen Mi, Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2016). Future role of molecular profiling in small breast samples and personalised medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 803-817) edited by Sandra J. Shin. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-26291-8_23
Saunus, Jodi M., McCart-Reed, Amy, Momeny, Majid, Cummings, Margaret and Lakhani, Sunil R. (2013). Breast cancer heterogeneity in primary and metastatic disease. Breast Cancer Metastasis and Drug Resistance: Challenges and Progress. (pp. 65-95) edited by Aamir Ahmad. New York, NY, USA: Springer. doi: 10.1007/978-1-4614-5647-6
Cummings, M. C., Winterford, C. M. and Walker, N. I. (1997). Apoptosis. Histology for pathologists. (pp. 3-21) edited by Stephen S. Sternberg. Philadelphia, PA United States: Lippencott-Raven.
Journal Articles
Baxter, Eva, Robledo, Kristy P., Cummings, Margaret, Alizart, Michelle, Smith, Deborah and Obermair, Andreas (2025). Central pathology review of endometrial hyperplasia and adenocarcinoma before and after treatment with the levonorgestrel intrauterine device–results from the feMMe phase 2 randomized clinical trial. American Journal of Surgical Pathology, 50 (2), 259-266. doi: 10.1097/pas.0000000000002492
Virassamy, Balaji, Caramia, Franco, Savas, Peter, Harris, Michael A., Pan, Jia-Wern, Wang, Jianan, Brown, Emmaline, O’Malley, Megan M. R., van Geelen, Courtney T., Hun, Michael, Burn, Thomas N., Sant, Sneha, Ballan, Jamieson D., Kay, Jasmine, Lara Gonzalez, Luis E., Clarke, Kylie, Aw Yeang, Han Xian, Idrizi, Rejhan, Jana, Metta, Challice, Damon J., Salgado, Roberto, Thorne, Heather, Zaheed, Milita, Young, Mary-Ann, Winship, Ingrid, Williams, Rachael, Walker, Logan, Visvader, Jane, Tucker, Kathy ... Loi, Sherene (2025). Parity and lactation induce T-cell-mediated breast cancer protection. Nature, 649 (8096), 449-459. doi: 10.1038/s41586-025-09713-5
Cummings, Margaret C., Vaux, David L., Strasser, Andreas and Kluck, Ruth (2024). John F. R. Kerr (1934-2024) (vol 31, pg 955, 2024). Cell Death and Differentiation, 31 (10), 1389-1389. doi: 10.1038/s41418-024-01373-8
Cummings, Margaret C., Vaux, David L., Strasser, Andreas and Kluck, Ruth (2024). John F. R. Kerr (1934-2024). Cell Death and Differentiation, 31 (8), 955-956. doi: 10.1038/s41418-024-01338-x
Lockshin, Richard A. and Cummings, Margaret C. (2022). The power of an idea: Andrew Wyllie. Cell Death & Differentiation, 29 (9), 1671-1672. doi: 10.1038/s41418-022-01043-7
Allanson, Emma R., Cummings, Margaret, Kuchel, Anna, Wastney, Timothy and Nicklin, Jim (2022). Undifferentiated uterine sarcoma: a multidisciplinary challenge. International Journal of Gynecological Cancer, 32 (2), 198-202. doi: 10.1136/ijgc-2021-003215
Tse, Ka-Yu, Wong, Richard Wing-Cheuk, Chao, Angel, Ueng, Shir-Hwa, Yang, Lan-Yan, Cummings, Margaret, Smith, Deborah, Lai, Chiung-Ru, Lau, Hei-Yu, Yen, Ming-Shyen, Cheung, Annie Nga-Yin, Leung, Charlotte Ka-Lun, Chan, Kit-Sheung, Chan, Alice Ngot-Htain, Li, Wai-Hon, Choi, Carmen Ka-Man, Pong, Wai-Mei, Hui, Hoi-Fong, Yuk, Judy Ying-Wah, Yao, Hung, Yuen, Nancy Wah-Fun, Obermair, Andreas, Lai, Chyong-Huey, Ip, Philip Pun-Ching and Ngan, Hextan Yuen-Sheung (2021). Development of a multi-institutional prediction model for three-year survival status in patients with uterine leiomyosarcoma (AGOG11-022/QCGC1302 study). Cancers, 13 (10) 2378, 2378. doi: 10.3390/cancers13102378
Janda, Monika, Robledo, Kristy P., Gebski, Val, Armes, Jane E., Alizart, Michelle, Brennan, Donal, Cummings, Margaret, Chen, Chen, Leung, Yee, Sykes, Peter, McNally, Orla, Oehler, Martin K., Walker, Graeme, Garrett, Andrea, Tang, Amy, Land, Russell, Nicklin, James L., Chetty, Naven, Perrin, Lewis C., Hoet, Greet, Sowden, Katherine, Eva, Lois, Tristram, Amanda and Obermair, Andreas (2021). Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: results of a randomized clinical trial. Gynecologic Oncology, 161 (1), 143-151. doi: 10.1016/j.ygyno.2021.01.029
Johnson, Nichola, Maguire, Sarah, Morra, Anna, Kapoor, Pooja Middha, Tomczyk, Katarzyna, Jones, Michael E., Schoemaker, Minouk J., Gilham, Clare, Bolla, Manjeet K., Wang, Qin, Dennis, Joe, Ahearn, Thomas U., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Aronson, Kristan J., Augustinsson, Annelie, Baynes, Caroline, Freeman, Laura E. Beane, Beckmann, Matthias W., Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Boeckx, Bram, Bogdanova, Natalia V., Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann ... Fletcher, Olivia (2021). CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. British Journal of Cancer, 124 (4), 842-854. doi: 10.1038/s41416-020-01185-w
Janda, Monika, Robledo, Kristy P., Gebski, Val, Armes, Jane E., Alizart, Michelle, Brennan, Donal, Cummings, Margaret, Chen, Chen, Leung, Yee, Sykes, Peter, McNally, Orla, Oehler, Martin K., GraemeWalker, , Garrett, Andrea, Tang, Amy, Land, Russell, Nicklin, James L., Chetty, Naven, Perrin, Lewis C., Hoet, Greet, Sowden, Katherine, Eva, Lois, Tristram, Amanda and Obermair, Andreas (2021). Corrigendum to “Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: Results of a randomized clinical trial” [Gynecologic Oncology 161 (2021) 143–151](S0090825821000895)(10.1016/j.ygyno.2021.01.029). Gynecologic Oncology, 162 (2), 526-526. doi: 10.1016/j.ygyno.2021.05.016
Kim, Woo Gyeong, Cummings, Margaret C. and Lakhani, Sunil R. (2020). Pitfalls and controversies in pathology impacting breast cancer management. Expert Review of Anticancer Therapy, 20 (3), 205-219. doi: 10.1080/14737140.2020.1738222
Fachal, Laura, Aschard, Hugues, Beesley, Jonathan, Barnes, Daniel R., Allen, Jamie, Kar, Siddhartha, Pooley, Karen A., Dennis, Joe, Michailidou, Kyriaki, Turman, Constance, Soucy, Penny, Lemaçon, Audrey, Lush, Michael, Tyrer, Jonathan P., Ghoussaini, Maya, Marjaneh, Mahdi Moradi, Jiang, Xia, Agata, Simona, Aittomäki, Kristiina, Alonso, M. Rosario, Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arason, Adalgeir, Arndt, Volker, Aronson, Kristan J., Arun, Banu K., Auber, Bernd, Auer, Paul L. ... Dunning, Alison M. (2020). Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nature Genetics, 52 (1), 56-73. doi: 10.1038/s41588-019-0537-1
Li, Anqi, Geyer, Felipe C., Blecua, Pedro, Lee, Ju Youn, Selenica, Pier, Brown, David N., Pareja, Fresia, Lee, Simon S. K., Kumar, Rahul, Rivera, Barbara, Bi, Rui, Piscuoglio, Salvatore, Wen, Hannah Y., Lozada, John R., Gularte-Mérida, Rodrigo, Cavallone, Luca, Aghmesheh, Morteza, Amor, David, Andrews, Leslie, Antill, Yoland, Balleine, Rosemary, Beesley, Jonathan, Blackburn, Anneke, Bogwitz, Michael, Brown, Melissa, Burgess, Matthew, Burke, Jo, Butow, Phyllis, Caldon, Liz ... Reis-Filho, Jorge S. (2019). Homologous recombination DNA repair defects in PALB2-associated breast cancers. npj Breast Cancer, 5 (1) 23. doi: 10.1038/s41523-019-0115-9
McCabe, Mark J., Gauthier, Marie-Emilie A., Chan, Chia-Ling, Thompson, Tanya J., De Sousa, Sunita M.C., Puttick, Clare, Grady, John P., Gayevskiy, Velimir, Tao, Jiang, Ying, Kevin, Cipponi, Arcadi, Deng, Niantao, Swarbrick, Alex, Thomas, Melissa L., Lord, Reginald V., Johns, Amber L., Kohonen-Corish, Maija, O’Toole, Sandra A., Clark, Jonathan, Mueller, Simon A., Gupta, Ruta, McCormack, Ann I., Dinger, Marcel E., Cowley, Mark J., Aghmesheh, Morteza, Amor, David, Andrews, Lesley, Antill, Yoland, Armitage, Shane ... Young, Mary-Anne (2019). Development and validation of a targeted gene sequencing panel for application to disparate cancers. Scientific Reports, 9 (1) 17052, 17052. doi: 10.1038/s41598-019-52000-3
Li, Anqi, Geyer, Felipe C., Blecua, Pedro, Lee, Ju Youn, Selenica, Pier, Brown, David N., Pareja, Fresia, Lee, Simon S. K., Kumar, Rahul, Rivera, Barbara, Bi, Rui, Piscuoglio, Salvatore, Wen, Hannah Y., Lozada, John R., Gularte-Mérida, Rodrigo, Cavallone, Luca, Aghmesheh, Morteza, Amor, David, Andrews, Leslie, Antill, Yoland, Balleine, Rosemary, Beesley, Jonathan, Blackburn, Anneke, Bogwitz, Michael, Brown, Melissa, Burgess, Matthew, Burke, Jo, Butow, Phyllis, Caldon, Liz ... Reis-Filho, Jorge S. (2019). Publisher Correction: Homologous recombination DNA repair defects in PALB2-associated breast cancers (npj Breast Cancer, (2019), 5, 1, (23), 10.1038/s41523-019-0115-9). npj Breast Cancer, 5 (1) 44. doi: 10.1038/s41523-019-0140-8
Figlioli, Gisella, Bogliolo, Massimo, Catucci, Irene, Caleca, Laura, Lasheras, Sandra Viz, Pujol, Roser, Kiiski, Johanna I., Muranen, Taru A., Barnes, Daniel R., Dennis, Joe, Michailidou, Kyriaki, Bolla, Manjeet K., Leslie, Goska, Aalfs, Cora M., Balleine, Rosemary, Baxter, Robert, Braye, Stephen, Carpenter, Jane, Dahlstrom, Jane, Forbes, John, Lee, C. Soon, Marsh, Deborah, Morey, Adrienne, Pathmanathan, Nirmala, Scott, Rodney, Simpson, Peter, Spigelman, Allan, Wilcken, Nicholas, Yip, Desmond ... Peterlongo, Paolo (2019). The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer. npj Breast Cancer, 5 (1) 38, 38. doi: 10.1038/s41523-019-0127-5
Kutasovic, Jamie R., McCart Reed, Amy E., Males, Renique, Sim, Sarah, Saunus, Jodi M., Dalley, Andrew, McEvoy, Christopher R., Dedina, Liana, Miller, Gregory, Peyton, Stephen, Reid, Lynne, Lal, Samir, Niland, Colleen, Ferguson, Kaltin, Fellowes, Andrew P., Al-Ejeh, Fares, Lakhani, Sunil R., Cummings, Margaret C. and Simpson, Peter T. (2019). Breast cancer metastasis to gynaecological organs: a clinico‐pathological and molecular profiling study. The Journal of Pathology: Clinical Research, 5 (1), 25-39. doi: 10.1002/cjp2.118
Joo, Jihoon E., Dowty, James G., Milne, Roger L., Wong, Ee Ming, Dugué, Pierre-Antoine, English, Dallas, Hopper, John L., Goldgar, David E., Giles, Graham G., Southey, Melissa C., kConFab, Sexton, Adrienne, Christian, Alice, Trainer, Alison, Spigelman, Allan, Fellows, Andrew, Shelling, Andrew, De Fazio, Anna, Blackburn, Anneke, Crook, Ashley, Meiser, Bettina, Patterson, Briony, Clarke, Christine, Saunders, Christobel, Hunt, Clare, Scott, Clare, Amor, David, Marsh, Deborah, Edkins, Edward ... Antill, Yoland (2018). Heritable DNA methylation marks associated with susceptibility to breast cancer. Nature Communications, 9 (1) 867. doi: 10.1038/s41467-018-03058-6
Kondrashova, Olga, Topp, Monique, Nesic, Ksenija, Lieschke, Elizabeth, Ho, Gwo-Yaw, Harrell, Maria I., Zapparoli, Giada V., Hadley, Alison, Holian, Robert, Boehm, Emma, Heong, Valerie, Sanij, Elaine, Pearson, Richard B., Krais, John J., Johnson, Neil, McNally, Orla, Ananda, Sumitra, Alsop, Kathryn, Hutt, Karla J., Kaufmann, Scott H., Lin, Kevin K., Harding, Thomas C., Traficante, Nadia, Chenevix-Trench, G., Green, A., Webb, P., Gertig, D., Fereday, S., Moore, S. ... Australian Ovarian Cancer Study (AOCS) (2018). Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma. Nature Communications, 9 (1) 3970, 3970. doi: 10.1038/s41467-018-05564-z
McCart Reed, Amy E., Kutasovic, Jamie R., Nones, Katia, Saunus, Jodi M., Da Silva, Leonard, Newell, Felicity, Kazakoff, Stephen, Melville, Lewis, Jayanthan, Janani, Vargas, Ana Cristina, Reid, Lynne E., Beesley, Jonathan, Chen, Xiao Qing, Patch, Anne Marie, David Clouston, D., Porter, Alan, Evans, Elizabeth, Pearson, John V., Chenevix-Trench, Georgia, Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R. and Simpson, Peter T. (2018). Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology. The Journal of Pathology, 244 (4), 460-468. doi: 10.1002/path.5040
Block, Matthew S., Vierkant, Robert A., Rambau, Peter F., Winham, Stacey J., Wagner, Philipp, Traficante, Nadia, Tołoczko, Aleksandra, Tiezzi, Daniel G., Taran, Florin Andrei, Sinn, Peter, Sieh, Weiva, Sharma, Raghwa, Rothstein, Joseph H., Ramón y Cajal, Teresa, Paz-Ares, Luis, Oszurek, Oleg, Orsulic, Sandra, Ness, Roberta B., Nelson, Gregg, Modugno, Francesmary, Menkiszak, Janusz, McGuire, Valerie, McCauley, Bryan M., Mack, Marie, Lubiński, Jan, Longacre, Teri A., Li, Zheng, Lester, Jenny, Kennedy, Catherine J. ... Goode, Ellen L. (2018). MyD88 and TLR4 expression in epithelial ovarian cancer. Mayo Clinic Proceedings, 93 (3), 307-320. doi: 10.1016/j.mayocp.2017.10.023
Hendry, Shona, Pang, Jia-Min B., Byrne, David J., Lakhani, Sunil R., Cummings, Margaret C., Campbell, Ian G., Mann, G. Bruce, Gorringe, Kylie L. and Fox, Stephen B. (2017). Relationship of the breast ductal carcinoma in situ immune microenvironment with clinicopathological and genetic features. Clinical Cancer Research, 23 (17), 5210-5217. doi: 10.1158/1078-0432.CCR-17-0743
Pang, Jia-Min B., Savas, Peter, Fellowes, Andrew P., Arnau, Gisela Mir, Kader, Tanjina, Vedururu, Ravikiran, Hewitt, Chelsee, Takano, Elena A., Byrne, David J., hoong, David Y. H., Millar, Ewan K. A., Lee, C. Soon, O'Toole, Sandra A., Lakhani, Sunil R., Cummings, Margaret C., Mann, G. Bruce, Campbell, Ian G., Dobrovic, Alexander, Loi, Sherene, Gorringe, Kylie L. and Fox, Stephen B. (2017). Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer. Modern Pathology, 30 (7), 952-963. doi: 10.1038/modpathol.2017.21
Packer, Leisl M., Geng, Xinyan, Bonazzi, Vanessa F., Ju, Robert J., Mahon, Clare E., Cummings, Margaret C., Stephenson, Sally-Anne and Pollock, Pamela M. (2017). PI3K inhibitors synergize with FGFR inhibitors to enhance antitumor responses in FGFR2mutant endometrial cancers. Molecular Cancer Therapeutics, 16 (4), 637-648. doi: 10.1158/1535-7163.MCT-16-0415
Cummings, M. C., Greaves, J., Shukor, R. A., Perkins, G. and Ross, J. (2017). Technical proficiency in cytopathology: assessment through external quality assurance. Cytopathology, 28 (2), 149-156. doi: 10.1111/cyt.12373
Field, Sarah, Uyttenhove, Catherine, Stroobant, Vincent, Cheou, Paméla, Coutelier, Jean-Paul, Simpson, Peter T., Cummings, Margaret C., Saunus, Jodi M., Reid, Lynne E., Kutasovic, Jamie R., McNicol, Anne Marie, Kim, Ba Reun, Kim, Jae Ho, Lakhani, Sunil R., Neville, A. Munro, Van Snick, Jacques and Jat, Parmjit S. (2016). Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer. International Journal of Cancer, 138 (8), 1959-1970. doi: 10.1002/ijc.29946
Pelttari, Liisa M., Khan, Sofia, Vuorela, Mikko, Kiiski, Johanna I., Vilske, Sara, Nevanlinna, Viivi, Ranta, Salla, Schleutker, Johanna, Winqvist, Robert, Kallioniemi, Anne, Dörk, Thilo, Bogdanova, Natalia V., Figueroa, Jonine, Pharoah, Paul D. P., Schmidt, Marjanka K., Dunning, Alison M., García-Closas, Montserrat, Bolla, Manjeet K., Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Hopper, John L., Southey, Melissa C., Rosenberg, Efraim H., Fasching, Peter A., Beckmann, Matthias W., Peto, Julian, Dos-Santos-silva, Isabel, Sawyer, Elinor J. ... Zeps, N. (2016). RAD51B in familial breast cancer. PLoS One, 11 (5) e0153788, e0153788. doi: 10.1371/journal.pone.0153788
Antill, Yoland C., Dowty, James G., Win, Aung Ko, Thompson, Tina, Walsh, Michael D., Cummings, Margaret C., Gallinger, Steven, Lindor, Noralane M., Le Marchand, Loic, Hopper, John L., Newcomb, Polly A., Haile, Robert W., Church, James, Tucker, Katherine M., Buchanan, Daniel D., Young, Joanne P., Winship, Ingrid M. and Jenkins, Mark A. (2015). Lynch syndrome and cervical cancer. International Journal of Cancer, 137 (11), 2757-2761. doi: 10.1002/ijc.29641
Saunus, Jodi M., Quinn, MIchael C. J., Patch, Ann-Marie, Pearson, John V., Bailey, Peter J., Nones, Katia, McCart Reed, Amy E., Miller, David, Peter J. Wilson, Al-Ejeh, Fares, Mariasegaram, Mythily, Lau, Queenie, Withers, Teresa, Jeffree, Rosalind L., Reid, Lynne E., Da Silva, Leonard, Matsika, Admire, Niland, Colleen M., Cummings, Margaret C., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Anderson, Matthew J., Fink, J. Lynn ... Lakhani, Sunil R. (2015). Integrated genomic and transcriptomic analysis of human brain metastases identifies recurrently altered pathways of potential clinical significance. Journal of Pathology, 237 (3), 363-378. doi: 10.1002/path.4583
Kumarasinghe, M. P., Cummings, M. C., Raymond, W., Shield, P., Judge, M., Beaty, A., Bethwaite, P., Braye, S., Carter, C. D., Chong, G., Downey, P., Frost, F., Loo, C., Nga, M. E., Nguyen, H., Panicker, V., Parker, A. J. C., Phillips, G., Salisbury, E., Twin, J. and Papadimos, D. (2015). Approach to thyroid cytology: rationale for standardisation. Pathology, 47 (4), 285-288. doi: 10.1097/PAT.0000000000000268
Cummings, Margaret C., Marquart, Louise, Pelecanos, Anita M., Perkins, Gail, Papadimos, David, O'Rourke, Peter and Ross, Jennifer A. (2015). Which are more correctly diagnosed: conventional Papanicolaou smears or ThinPrep samples? A comparative study of 9 tears of external quality-assurance testing. Cancer Cytopathology, 123 (2), 108-116. doi: 10.1002/cncy.21498
Buchanan, Daniel D., Tan, Yen Y., Walsh, Michael D., Clendenning, Mark, Metcalf, Alexander M., Ferguson, Kaltin, Arnold, Sven T., Thompson, Bryony A., Lose, Felicity A., Parsons, Michael T., Walters, Rhiannon J., Pearson, Sally-Ann, Cummings, Margaret, Oehler, Martin K., Blomfield, Penelope B., Quinn, Michael A., Kirk, Judy A., Stewart, Colin J., Obermair, Andreas, Young, Joanne P., Webb, Penelope M. and Spurdle, Amanda B. (2014). Reply to J. Moline et al. Journal of Clinical Oncology, 32 (21), 2278-2279. doi: 10.1200/JCO.2014.55.8213
Generali, D., Buffa, F. M., Deb, S., Cummings, M., Reid, L. E., Taylor, M., Andreis, D., Allevi, G., Ferrero, G., Byrne, D., Martinotti, M., Bottini, A., Harris, A. L., Lakhani, S. R. and Fox, S. B. (2014). COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment. British Journal of Cancer, 111 (1), 46-54. doi: 10.1038/bjc.2014.236
Kutasovic, Jamie R., Sim, Sarah Y. M., McCart Reed, Amy E., Cummings, Margaret C. and Simpson, Peter T. (2014). Intratumour heterogeneity in the progression to breast cancer metastasis. Cancer Forum, 38 (2), 138-142.
Vuong, Darina, Simpson, Peter T., Green, Benjamin, Cummings, Margaret C. and Lakhani, Sunil R. (2014). Molecular classification of breast cancer. Virchows Archiv, 465 (1), 1-14. doi: 10.1007/s00428-014-1593-7
Buchanan, Daniel D., Tan, Yen Y., Walsh, Michael D., Clendenning, Mark, Metcalf, Alexander M., Ferguson, Kaltin, Arnold, Sven T., Thompson, Bryony A., Lose, Felicity A., Parsons, Michael T., Walters, Rhiannon J., Pearson, Sally-Ann, Cummings, Margaret, Oehler, Martin K., Blomfield, Penelope B., Quinn, Michael A., Kirk, Judy A., Stewart, Colin J., Obermair, Andreas, Young, Joanne P., Webb, Penelope M. and Spurdle, Amanda B. (2014). Tumor mismatch repair immunohistochemistry and DNA MLH1 methylation testing of patients with endometrial cancer diagnosed at age younger than 60 years optimizes triage for population-level germline mismatch repair gene mutation testing. Journal of Clinical Oncology, 32 (2), 90-100. doi: 10.1200/JCO.2013.51.2129
Tilch, E., Seidens, T., Cocciardi, S., Reid, L. E., Byrne, D., Simpson, P. T., Vargas, A. C., Cummings, M. C., Fox, S. B., Lakhani, S. R. and Chenevix Trench, G. (2014). Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women. Breast Cancer Research and Treatment, 143 (2), 385-392. doi: 10.1007/s10549-013-2798-1
Cummings, Margaret C., Simpson, Peter T., Reid, Lynne E., Jayanthan, Janani, Skerman, Joanna, Song, Sarah, McCart Reed, Amy E., Kutasovic, Jamie R., Morey, Adrienne L., Marquart, Louise, O'Rourke, Peter and Lakhani, Sunil R. (2014). Metastatic progression of breast cancer: Insights from 50 years of autopsies. Journal of Pathology, 232 (1), 23-31. doi: 10.1002/path.4288
Walsh, Michael D., Cummings, Margaret C., Pearson, Sally-Ann, Clendenning, Mark, Walters, Rhiannon J., Nagler, Belinda, Hopper, John L., Jenkins, Mark A., Suthers, Graeme K., Goldblatt, Jack, Tucker, Kathy, Gattas, Michael R., Arnold, Julie L., Parry, Susan, Macrae, Finlay A., McGuckin, Michael A., Young, Joanne P. and Buchanan, Daniel D. (2013). Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins. Modern Pathology, 26 (7), 944-954. doi: 10.1038/modpathol.2012.232
Hosein, Abdel Nasser, Song, Sarah, McCart Reed, Amy E., Jayanthan, Janani, Reid, Lynne E., Kutasovic, Jamie R., Cummings, Margaret C., Waddell, Nic, Lakhani, Sunil R., Chenevix-Trench, Georgia and Simpson, Peter T. (2013). Evaluating the repair of DNA derived from formalin-fixed paraffin-embedded tissues prior to genomic profiling by SNP-CGH analysis. Laboratory Investigation, 93 (6), 701-710. doi: 10.1038/labinvest.2013.54
Waldron, Levi, Ogino, Shuji, Hoshida, Yujin, Shima, Kaori, Reed, Amy E. McCart, Simpson, Peter T., Baba, Yoshifumi, Nosho, Katsuhiko, Segata, Nicola, Vargas, Ana Cristina, Cummings, Margaret C., Lakhani, Sunil R., Kirkner, Gregory J., Giovannucci, Edward, Quackenbush, John, Golub, Todd R., Fuchs, Charles S., Parmigiani, Giovanni and Huttenhower, Curtis (2012). Expression profiling of archival tumors for long-term health studies. Clinical Cancer Research, 18 (22), 6136-6146. doi: 10.1158/1078-0432.CCR-12-1915
Bilous, Michael, Adrienne L. Morey, Armes, Jane E., Bell, Richard, Button, Peter H., Cummings, Margaret C., Fox, Stephen B., Francis, Glenn D., Waite, Brigid, McCue, Glenda, Raymond, Wendy A., Robbins, Peter D. and Farshid, Gelareh (2012). Assessing HER2 amplification in breast cancer: findings from the Australian In Situ Hybridization Program. Breast Cancer Research and Treatment, 134 (2), 617-624. doi: 10.1007/s10549-012-2093-6
Fox, Stephen B., Kumarasinghe, Marian Priyanthi, Armes, Jane E., Bilous, Michael, Cummings, Margaret C., Farshid, Gelareh, Fitzpatrick, Nicole, Francis, Glenn D., McCloud, Philip I., Raymond, Wendy and Morey, Adrienne (2012). Gastric HER2 testing study (GaTHER): An evaluation of gastric/ gastroesophageal junction cancer testing accuracy in Australia. American Journal of Surgical Pathology, 36 (4), 577-582. doi: 10.1097/PAS.0b013e318244adbb
McCart Reed, Amy E., Cummings, Margaret C., Lakhani, Sunil R. and Simpson, Peter T. (2012). Molecular pathology of pre-invasive breast disease in the screening setting: Application in diagnosis and management. Diagnostic Histopathology, 18 (2), 64-69. doi: 10.1016/j.mpdhp.2011.11.006
Alizart, Michelle, Saunus, Jodi, Cummings, Margaret and Lakhani, Sunil R. (2012). Molecular classification of breast carcinoma. Diagnostic Histopathology, 18 (3), 97-103. doi: 10.1016/j.mpdhp.2011.12.003
Cummings, M.C., Waters, B.A. and Rourke, P.K.O. (2011). Breast fine needle aspiration cytology: a review of current practice in Australasia. Cytopathology, 22 (4), 269-275. doi: 10.1111/j.1365-2303.2010.00788.x
Ramus, Susan J., Kartsonaki, Christiana, Gayther, Simon A., Pharoah, Paul D. P., Sinilnikova, Olga M., Beesley, Jonathan, Chen, Xiaoqing, McGuffog, Lesley, Healey, Sue, Couch, Fergus J., Wang, Xianshu, Fredericksen, Zachary, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Zaffaroni, Daniela, Roversi, Gaia, Barile, Monica, Viel, Alessandra, Allavena, Anna, Ottini, Laura, Papi, Laura, Gismondi, Viviana, Capra, Fabio, Radice, Paolo, Greene, Mark H., Mai, Phuong L., Andrulis, Irene L., Glendon, Gord ... Lakhani, Sunil (2011). Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Journal of the National Cancer Institiute, 103 (2), 105-116. doi: 10.1093/jnci/djq494
Cummings, Margaret C., Chambers, Rachael, Simpson, Peter T. and Lakhani, Sunil R. (2011). Molecular classification of breast cancer: Is it time to pack up our microscopes?. Pathology, 43 (1), 1-8. doi: 10.1097/PAT.0b013e328341e0b5
Shield, Paul W., Finnimore, Jo, Cummings, Margaret and Wright, R. Gordon (2010). Performance measures for Australian laboratories reporting cervical cytology: A decade of data 1998-2008. Pathology, 42 (7), 623-628. doi: 10.3109/00313025.2010.520308
Balleine, Rosemary L., Provan, Pamela J., Pupo, Gulietta M., Pathmanathan, Nirmala, Cummings, Margaret, Farshid, Gelareh, Salisbury, Elizabeth L., Bilous, A. Michael, Byth, Karen and Mann, Graham J. (2010). Familial concordance of breast cancer pathology as an indicator of genotype in multiple-case families. Genes, Chromosomes and Cancer, 49 (12), 1082-1094. doi: 10.1002/gcc.20816
Farshid, Gelareh, Armes, Jane E., Bell, Richard, Cummings, Margaret, Fox, Stephen, Francis, Glenn, Haswell, Martin, Morey, Adrienne, McCue, Glenda, Raymond, Wendy, Robbins, Peter and Bilous, Michael (2010). Establishment of the Australian in situ hybridization program for the assessment of HER2 amplification in breast cancer: A model for the introduction of new biomarkers into clinical practice. Diagnostic Molecular Pathology, 19 (4), 187-193. doi: 10.1097/PDM.0b013e3181e1cc9d
Mia M. Gaudet, Tomas Kirchhoff, Todd Green, Joseph Vijai, Joshua M. Korn, Candace Guiducci, Ayellet V. Segre, Kate McGee, Lesley McGuffog, Christiana Kartsonaki, Jonathan Morrison, Sue Healey, Olga M. Sinilnikova, Dominique Stoppa-Lyonnet, Sylvie Mazoyer, Marion Gauthier-Villars, Hagay Sobol, Michel Longy, Marc Frenay, GEMO Study Collaborators, Frans B. L. Hogervorst, Matti a. Rookus, J. Margriet Collee, Nicoline Hoogerbrugge, Kees E. P. van Roozendaal, HEBON Study Collaborators, Marion Piedmonte, Wendy Rubinstein, Stacy Nerenstone ... Lakhani, Sunil (2010). Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. PLoS Genetics, 6 (10), e1001183-1-e1001183-12. doi: 10.1371/journal.pgen.1001183
Antoniou, Antonis C., Wang, Xianshu, Fredericksen, Zachary S., McGuffog, Lesley, Tarrell, Robert, Sinilnikova, Olga M., Healey, Sue, Morrison, Jonathan, Kartsonaki,Christiana, Lesnick, Timothy, Ghoussaini, Maya, Barrowdale, Daniel, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Eccles, Diana, Evans, D. Gareth, Eeles, Ros, Izatt, Louise, Chu, Carol, Douglas, Fiona, Paterson, Joan, Stoppa-Lyonnet, Dominique, Houdayer, Claude, Mazoyer, Sylvie, Giraud, Sophie, Lasset, Christine, Remenieras, Audrey ... Lakhani, Sunil (2010). A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population. Nature Genetics, 42 (10), 885-892. doi: 10.1038/ng.669
Wang, Xianshu, Pankratz, V. Shane, Fredericksen, Zachary, Tarrell, Robert, Karaus, Mary, McGuffog, Lesley, Pharaoh, Paul D.P., Ponder, Bruce A.J., Dunning, Alison M., Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, EMBRACE, Sinilnikova, Olga M., Stoppa-Lyonnet, Dominique, Mazoyer, Sylvie, Houdayer, Claude, GEMO, Hogervorst, Frans B.L., Hooning, Maartje J., Ligtenberg, Marjolijn J., HEBON, Spurdle, Amanda, Chenevix-Trench, Georgia, kConFab, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph ... Lakhani, Sunil (2010). Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics, 19 (14), 2886-2897. doi: 10.1093/hmg/ddq174
Walsh, MD, Buchanan, DD, Cummings, MC, Pearson, SA, Arnold, ST, Clendenning, M, Walters, R, McKeone, DM, Spurdle, AB, Hopper, JL, Jenkins, MA, Phillips, KD, Suthers, GK, George, J, Goldblatt, J, Muir, A, Tucker, K, Pelzer, E, Gattas, MR, Woodall, S, Parry, S, Macrae, FA, Haile, RW, Baron, JA, Potter, JD, Le Marchand, L, Bapat, B, Thibodeau, SN, Lindor, NM ... Young, JP (2010). Lynch syndrome-associated breast cancers: Clinicopathologic characteristics of a case series from the colon cancer family registry. Clinical Cancer Research, 16 (7), 2214-2224. doi: 10.1158/1078-0432.CCR-09-3058
Flanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 (3), 420-433. doi: 10.1016/j.ajhg.2010.02.008
Arnold, Jeremy M., Choong, David Y. H., Thompson, Ella R., kConFab, Waddell, Nic, Lindeman, Geoffrey J., Visvader, Jane E., Campbell, Ian G., Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors. Breast Cancer Research And Treatment, 119 (2), 491-496. doi: 10.1007/s10549-008-0269-x
Da Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603
Cummings, Margaret C., Da Silva, Leonard, Papadimos, David J. and Lakhani, Sunil R. (2009). Fibroadenoma and intraduct papilloma--a common pathogenesis?. Virchows Archiv, 455 (3), 271-275. doi: 10.1007/s00428-009-0817-8
Houston, AM, Michael-Robinson, JM, Walsh, MD, Cummings, MC, Ryan, AE, Lincoln, D, Pandeya, N, Jass, JR, Radford-Smith, GL and O'Connell, J (2008). The "Fas counterattack" is not an active mode of tumor immune evasion in colorectal cancer with high-level microsatellite instability. Human Pathology, 39 (2), 243-250. doi: 10.1016/j.humpath.2007.06.010
Walsh, M. D., Cummings, M. C., Buchanan, D. D., Dambacher, W. M., Arnold, S., McKeone, D., Byrnes, R., Barker, M. A., Leggett, B. A., Gattas, M., Jass, J. R., Spurdle, A. B., Young, J. and Obermair, A. (2008). Molecular, pathologic, and clinical features of early-onset endometrial cancer: Identifying presumptive Lynch Syndrome patients. Clinical Cancer Research, 14 (6), 1692-1700. doi: 10.1158/1078-0432.CCR-07-1849
Richmond-Sinclair, N.M., Lee, E., Cummings, M.C., Williamson, R., Muller, H.K., Green, A.C., Hayward, N.K. and Whiteman, D.C. (2008). Histologic and epidemiologic correlates of P-MAPK, Brn-2, pRb, p53 and p16 immunostaining in cutaneous melanomas. Melanoma research, 18 (5), 336-345. doi: 10.1097/CMR.0b013e32830d8329
Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D. P., Thompson, Deborah, Ballinger, Dennis G., Struewing, Jeffery P., Morrison, Jonathan, Field, Helen, Luben, Robert, Wareham, Nicholas, Ahmed, Shahana, Healey, Catherine S., Bowman, Richard, SEARCH collaborators, Meyer, Kerstin B., Haiman, Christopher A., Kolonel, Laurence K., Henderson, Brian E., Marchand, Loic Le, Brennan, Paul, Sangrajrang, Suleeporn, Gaborieau, Valerie, Odefrey, Fabrice, Shen, Chen-Yang, Wu, Pei-Ei, Wang, Hui-Chun, Eccles Diana, Evans, D. Gareth ... Ward, Robyn (2007). Genome-wide association study identifies novel breast cancer susceptibility loci. Nature, 447 (7148), 1087-1093. doi: 10.1038/nature05887
Herath, Nirmitha I., Spanevello, Mark D., Sabesan, Sabe, Newton, Tanya, Cummings, Margaret, Duffy, Shannon, Lincoln, Douglas, Boyle, Glen, Parsons, Peter G. and Boyd, Andrew W. (2006). Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival. BMC Cancer, 6 (144) 144, 144. doi: 10.1186/1471-2407-6-144
Chenevix-Trench, Georgia, Healey, Sue, Lakhani, Sunil, Waring, Paul, Cummings, Margaret, Brinkworth, Ross, Deffenbaugh, Amie M., Burbidge, Lynn Anne, Pruss, Dmitry, Judkins, Thad, Scholl, Tom, Bekessy, Anna, Marsh, Anna, Lovelock, Paul, Wong, Ming, Tesoriero, Andrea, Renard, Helene, Southey, Melissa, Hopper, John L., Yannoukakos, Koulis, Brown, Melissa, kConFab Investigators, Easton, Douglas, Tavtigian, Sean V., Goldgar, David and Spurdle, Amanda B. (2006). Genetic and Histopathologic Evaluation of BRCA1 and BRCA2 DNA Sequence Variance of Unknown Clinical Significance. Cancer Research, 66 (4), 2019-2027. doi: 10.1158/0008-5472.CAN-05-3546
Bilous, Michael, Morey, Adrienne, Armes, Jane, Cummings, Margaret and Francis, Glenn (2006). Chromogenic in situ hybridisation testing for HER2 gene amplification in breast cancer produces highly reproducible results concordant with fluorescence in situ hybridisation and immunohistochemistry. Pathology, 38 (2), 120-124. doi: 10.1080/00313020600561518
Farshid, G, Balleine, RL, Cummings, M, Waring, P and kConFab Grp (2006). Morphology of breast cancer as a means of triage of patients for BRCA1 genetic testing. American Journal of Surgical Pathology, 30 (11), 1357-1366. doi: 10.1097/01.pas.0000213273.22844.1a
Newton, Tanya R., Parsons, Peter G., Lincoln, Douglas J., Cummings, Margaret C., Wyld, David K., Webb, Penelope M., Green, Adele C. and Boyle, Glen M. (2006). Expression profiling correlates with treatment response in women with advanced serous epithelial ovarian cancer. International Journal of Cancer, 119 (4), 875-883. doi: 10.1002/ijc.21823
Arnold, J. M., Huggard, P. R., Cummings, M., Ramm, G. A. and Chenevix-Trench, G. (2005). Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma. British Journal of Cancer, 92 (11), 2024-2031. doi: 10.1038/sj.bjc.6602596
Webb, PM, Cummings, MC, Bain, CJ and Furnival, CM (2004). Changes in survival after breast cancer: improvements in diagnosis or treatment?. Breast, 13 (1), 7-14. doi: 10.1016/S0960-9776(03)00129-2
Michael-Robinson, Julie M., Pandeya, Nirmala, Cummings, Margaret C., Walsh, Michael D., Young, Joanne P., Leggett, Barbara A., Purdie, David M., Jass, Jeremy R. and Radford-Smith, Graham L. (2003). Fas ligand and tumour counter-attack in colorectal cancer stratified according to microsatellite instability status. Journal of Pathology, 201 (1), 46-54. doi: 10.1002/path.1406
Cummings, M. C. (2003). Occult metastases in breast cancer. Cancer Forum, 27 (2), 95-97.
Bilous, M., Ades, C., Armes, J., Bishop, J., Brown, R., Cooke, B., Cummings, M., Farshid, G., Field, A., Morey, A., McKenzie, P., Raymond, W., Robbins, P. and Tan, L. (2003). Predicting the HER2 status of breast cancer from basic histopathology data: an analysis of 1500 breast cancers as part of the HER2000 International Study. Breast, 12 (2), 92-98. doi: 10.1016/S0960-9776(02)00273-4
Cummings, M. C., Walsh, M. D., Hohn, B. G, Bennett, I. C., Wright, R. G. and McGuckin, M. A. (2002). Occult axillary lymph node metastases in breast cancer do matter: results of 10-year survival analysis. American Journal of Surgical Pathology, 26 (10), 1286-1295. doi: 10.1097/00000478-200210000-00005
Whiteman, David C., Zhou, Xiao-Ping, Cummings, Margaret C., Pavey, Sandra, Hayward, Nicholas K. and Eng, Charis (2002). Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma. International Journal of Cancer, 99 (1), 63-67. doi: 10.1002/ijc.10294
Chenevix-Trench, Georgia, Spurdle, Amanda B., Gatei, Magtouf, Kelly, Helena, Marsh, Anna, Chen, Xiaoqing, Donn, Karen, Cummings, Margaret C., Nyholt, Dale, Jenkins, Mark A., Scott, Clare, Pupo, Gulietta M., Dork, Thilo, Bendix, Regina, Kirk, Judy, Tucker, Katherine, McCredie, Margaret R. E., Hopper, John L., Sambrook, Joseph, Mann, Graham J. and Khanna, Kum Kum (2002). Dominant negative ATM mutations in breast cancer families. Journal of the National Cancer Institute, 94 (3), 205-215. doi: 10.1093/jnci/94.3.205
Pavey, S. J., Cummings, M. C., Whiteman, D. C., Castellano, M., Walsh, M. D., Gabrielli, B. G., Green, A. and Hayward, N. K. (2002). Loss of p16 expression is associated with histological features of melanoma invasion. Melanoma Research, 12 (6), 539-547. doi: 10.1097/01.cmr.0000043154.28051.9f
Arnold, J. M., Cummings, M., Purdie, D. and Chenevix-Trench, G. (2001). Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas. British Journal of Cancer, 85 (9), 1351-1358. doi: 10.1054/bjoc.2001.2075
Bilous, Michael, Ades, Colin, Armes, Jane, Bell, Richard, Brown, Robert, Cook, Bridget, Cummings, Margaret C., Field, Andrew, Llewellyn, Huw, McKenzie, Paul, Raymond, Wendy, Robbins, Peter and Tan, Lisa (2001). HER2 testing recommendations in Australia. Pathology, 33 (4), 425-427. doi: 10.1080/00313020120083133
Bellomo, D., Headrick, J. P., Silins, G. U., Paterson, C. A., Thomas, P. S., Gartside, M., Mould, A., Cahill, M. M., Tonks, I. D., Grimmond, S. M., Wells, C. A., Little, M. H., Cummings, M. C., Hayward, N. K. and Kay, G. F. (2000). Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia. Circulation Research, 86 (2), E29-E35.
Boonchai, Waranya, Walsh, Michael, Cummings, Margaret and Chenevix-Trench, Georgia (2000). Expression of p53 in arsenic-related and sporadic basal cell carcinoma. Archives of Dermatology, 136 (2), 195-198. doi: 10.1001/archderm.136.2.195
Boonchai, W., Walsh, M., Cummings, M. C. and Chenevix-Trench, G. (2000). Expression of b-catenin, a key mediator of the wnt signaling pathway, in basal cell carcinoma. Archives of Dermatology, 136 (7), 937-938. doi: 10.1001/archderm.136.7.937
Cummings, M. C., Aubele, M., Mattis, A., Purdie, D., Hutzler, P., Hofler, H. and Werner, M. (2000). Increasing chromosome 1 copy number parallels histological progression in breast carcinogenesis. British Journal of Cancer, 82 (6), 1204-1210. doi: 10.1054/bjoc.1999.1064
Aubele, M., Cummings, M. C., Walch, A. K., Zitzelsberger, H., Nahrig, J., Hofler, H. and Werner, M. (2000). Heterogeneous chromosomal aberrations in intraductal breast lesions adjacent to invasive carcinoma. Analytical Cellular Pathology, 20 (1), 17-24. doi: 10.1155/2000/930246
Aubele, M. M., Cummings, M. C., Mattis, A. E., Zitzelsberger, H. F., Walch, A. K., Kremer, M., Hofler, H. and Werner, M (2000). Accumulation of chromosomal imbalances from intraductal proliferative lesions to adjacent in situ and invasive ductal breast cancer. Diagnostic Molecular Pathology, 9 (1), 14-19. doi: 10.1097/00019606-200003000-00003
Werner, M., Mattis, A., Aubele, M., Cummings, M. C., Zitzelsberger, H., Hutzler, P. and Hofler, H. (1999). 20q13.2 amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast.. Virchows Archiv, 435 (5), 469-472. doi: 10.1007/s004280050429
Wright, Kim, Wilson, Peter, Morland, Sarah, Campbell, Ian, Walsh, Michael, Hurst, Terry G., Ward, Bruce G., Cummings, Margaret C. and Chenevix-Trench, Georgia (1999). Beta-catenin mutation and expression analysis in ovarian cancer: Exon 3 mutations and nuclear translocation in 16% of endometrioid tumour. International Journal of Cancer, 82 (5), 625-629. doi: 10.1002/(SICI)1097-0215(19990827)82:5
Cummings, MC, Winterford, CM and Walker, NI (1999). Apoptosis - Reply. American Journal of Surgical Pathology, 23 (7), 862-862. doi: 10.1097/00000478-199907000-00020
Jass, J. R., Biden, K. G., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., Metlzer, S. J., Wright, C., Searle, J., Young, J. and Leggett, B. A. (1999). Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. Journal of Clinical Pathology, 52 (6), 455-460. doi: 10.1136/jcp.52.6.455
Biden, Kelli G., Simms, Lisa A., Cummings, Margaret, Buttenshaw, Ron, Schoch, Estelle, Searle, Jeffrey, Gobe, Glenda, Jass, Jeremy R., Meltzer, Stephen J., Leggett, Barbara A. and Young, Joanne (1999). Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability. Oncogene, 18 (5), 1245-1249. doi: 10.1038/sj.onc.1202413
Walsh, M. D., Luckie, S. M., Cummings, M. C., Antalis, T. M. and McGuckin, M. A. (1999). Heterogeneity of MUC1 expression by human breast carcinoma cell lines in vivo and in vitro. Breast Cancer Research & Treatment, 58 (3), 253-264. doi: 10.1023/A:1006345301364
Shield, P. W., Nolan, G., Phillips, G. E. and Cummings, M. C. (1999). Improving cervical cytology screening in a remote, high risk population.. Medical Journal of Australia, 170 (6), 255-258.
Webb, Penelope M., Green, Adèle, Cummings, Margaret C., Purdie, David M., Walsh, Michael D. and Chenevix-Trench, Georgia (1998). Relationship between number of ovulatory cycles and accumulation of mutant p53 in epithelial ovarian cancer. Journal of the National Cancer Institute, 90 (22), 1729-1734. doi: 10.1093/jnci/90.22.1729
Simms, Lisa A., Radford-Smith, Graham, Biden, Kelli G., Buttenshaw, Ron, Cummings, Margaret, Jass, Jeremy R., Young, Joanne, Meltzer, Stephen J. and Leggett, Barbara A. (1998). Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers. Oncogene, 17 (15), 2003-2008. doi: 10.1038/sj.onc.1202109
Dong, Y., Walsh, M.D., Cummings, M.C., Wright, R.G., Khoo, S.K., Parsons, P.G. and McGuckin, M.A. (1997). Expression of MUC1 and MUC2 mucins in epithelial ovarian tumours. Journal of Pathology, 183 (3), 311-317. doi: 10.1002/(SICI)1096-9896(199711)183:3<311::AID-PATH917>3.0.CO;2-2
Dong, Y, Walsh, MD, McGuckin, MA, Cummings, MC, Gabrielli, BG, Wright, GR, Hurst, T, Khoo, SK and Parsons, PG (1997). Reduced expression of retinoblastoma gene product (pRB) and high expression of p53 are associated with poor prognosis in ovarian cancer. International Journal of Cancer, 74 (4), 407-415. doi: 10.1002/(SICI)1097-0215(19970822)74:4<407::AID-IJC8>3.0.CO;2-Z
ChenevixTrench, G, Coombs, T, Kerr, J, Purdie, D, Green, A and Cummings, MC (1997). Fertility and incidence of KRAS2 mutations in borderline ovarian adenocarcinomas. Journal of the National Cancer Institute, 89 (12), 890-891. doi: 10.1093/jnci/89.12.890
Dong, Y., Walsh, M.D., McGuckin, M.A., Gabrielli, B.G., Cummings, M.C., Wright, R.C., Hurst, T., Khoo, S.K. and Parsons, P.G. (1997). Increased expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product p16(INK4A) in ovarian cancer is associated with progression and unfavourable prognosis. International Journal of Cancer, 74 (1), 57-63. doi: 10.1002/(SICI)1097-0215(19970220)74:1<57::AID-IJC10>3.0.CO;2-F
Cummings, MC, Winterford, CM and Walker, NI (1997). Apoptosis. American Journal of Surgical Pathology, 21 (1), 88-101. doi: 10.1097/00000478-199701000-00010
Cummings, M.C. (1996). Increased p53 mRNA expression in liver and kidney apoptosis. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1315 (2), 100-104. doi: 10.1016/0925-4439(95)00104-2
McGuckin, M. A., Cummings, M. C., Walsh, M. D., Hohn, B. G., Bennett, I. C. and Wright, R. G. (1996). Occult axillary node metastases in breast cancer: Their detection and prognostic significance. British Journal of Cancer, 73 (1), 88-95. doi: 10.1038/bjc.1996.16
Cummings M. (1996). Apoptosis of epithelial cells in vivo involves tissue transglutaminase upregulation. Journal of Pathology, 179 (3), 288-293. doi: 10.1002/(SICI)1096-9896(199607)179:3<288::AID-PATH574>3.0.CO;2-M
CLARKE, AR, CUMMINGS, MC and HARRISON, DJ (1995). INTERACTION BETWEEN MURINE GERMLINE MUTATIONS IN P53 AND APC PREDISPOSES TO PANCREATIC NEOPLASIA BUT NOT TO INCREASED INTESTINAL MALIGNANCY. Oncogene, 11 (9), 1913-1920.
Cummings M. (1995). Increased c-fos expression associated with hyperthermia-induced apoptosis of a burkitt lymphoma cell line. International Journal of Radiation Biology, 68 (6), 687-692. doi: 10.1080/09553009514551701
Cummings, M. C., Wright, R. G., Furnival, C. M., Bain, C. J. and Siskind, V. (1995). The feasibility of retrospective grading of breast cancer histology slides derived from multiple pathology services. The Breast, 4 (3), 179-182. doi: 10.1016/0960-9776(95)90073-X
Cummings, M. C., Furnival, C. M., Parsons, P. G. and Townsend, E. (1993). PCNA immunostaining in breast cancer. Australian and New Zealand Journal of Surgery, 63 (8), 630-636. doi: 10.1111/j.1445-2197.1993.tb00471.x
WARREN, RJ, CUMMINGS, MC, MULLERWORTH, MHW, BIERRE, AR and HUNT, D (1987). LUNG-CARCINOMA PRESENTING WITH SYSTEMIC EMBOLISM - AN UNCOMMON DIFFERENTIAL-DIAGNOSIS FOR ATRIAL-MYXOMA. Medical Journal of Australia, 147 (3), 150-151.
Conference Papers
Gounden, S., Obermair, A., Garrett, A., Mar Fan, H. and Cummings, M. (2023). Age is the best predictor of MLH1 promotor methylation in mismatch repair deficient endometrial carcinoma. Pathology Update 2023, Melbourne, VIC, Australia, 24-26 February 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2022.12.182
Stacey, A., Simpson, P., McCart-Reed, A. and Cummings, M. (2022). Breast cancer in Honiara - a retrospective audit. 34th International Congress of the International Academy of Pathology, Sydney, NSW Australia, 1-15 October 2022. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/his.14739
Kutasovic, Jamie, Reed, Amy McCart, Sim, Sarah, Cummings, Margaret, Lakhani, Sunil and Simpson, Peter (2015). Breast cancer metastasis to gynaecological organs: impacting young women diagnosed with a luminal tumour subtype. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, June 28th–July 1st, 2014. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/s10585-015-9708-3
Da Silva, Leonard, McCart Reed, Amy E., Kutasovic, Jamie R., Vargas, Ana Cristina, Jayanthan, Janani, Reid, Lynne, Fritz, Brian, Cummings, Margaret C., Porter, Alan, Evans, Elizabeth, Lakhani, Sunil R. and Simpson, Peter T. (2012). Abrogated cell-cell adhesion in the phenotypic drift from ductal to lobular breast cancer types. 24th Lorne Cancer Conference 2012, Lorne, VIC, Australia, 9-11 February 2012.
Walsh, M. D., Cummings, M. C., Buchanan, D. D., Arnold, S., Mckeone, D. M., Walters, R., Hopper, J. L., Jenkins, M. A., Mcguckin, M. A. and Young, J. (2010). Lynch syndrome-associated breast cancers: clinicopathological characteristics of a case series from the colon CFR. Australian Gastroenterology Week 2010, Gold Coast, QLD, Australia, 20-23 October 2010. Richmond, VIC, Australia: John Wiley & Sons.
Ross, J. and Cummings, M. C. (2010). EXTERNAL QUALITY ASSURANCE: THE AUSTRALIAN EXPERIENCE. ST LOUIS: SCI PRINTERS & PUBL INC.
Rosty, Christophe, Walsh, Michael, Cummings, Margaret, Buchanan, Daniel, Arnold, Sven, McKeone, Diane, Walters, Rhiannon, Hopper, John, Jenkins, Mark, Spurdle, Amanda, McGuckin, Michael, Lakhani, Sunil and Young, Joanne (2010). Lynch syndrome-associated breast cancers: clinicopathological characteristics of a case series from the Colon CFR. AACR 101st Annual Meeting 2010, Washington, DC, United States, 17-21 April 2010. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM10-32
Farshid, G., Armes, J. E., Bell, R., Cummings, M., Fox, S., Francis, G., Haswell, M., Morey, A., McCue, G., Raymond, W., Robbins, P. and Bilous, M. (2010). Establishment of the Australian in situ hybridisation program for the assessment of HER2 amplification in breast cancer: a model for the introduction of new biomarkers into clinical practice. 99th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Washington, DC, United States, 20-26 March 2010. Amsterdam, Netherlands: Elsevier.
Walsh, M., Cummings, M., Buchanan, D., Arnold, S., McKeone, D., Walters, R., Jass, J., Hopper, J., Jenkins, M., Spurdle, A., McGuckin, M. and Young, J. (2008). DNA mismatch repair deficiency in breast cancers arising in breast/colon families. 27th International Congress of the International-Academy-of-Pathology, Athens, Greece, 12-17 October 2008. Oxford, United Kingdom: John Wiley & Sons.
Walsh, M, Young, J, Cummings, M, Buchanan, D, Barker, M, Gattas, M, Leggett, B, Jeremy, J, Spurdle, A and Obermair, A (2006). DNA mismatch repair deficiency in early-onset endometrial carcinomas. 26th International Congress of the International-Academy-of-Pathology, Montreal Canada, Sep 16-21, 2006. NEW YORK: NATURE PUBLISHING GROUP.
Bilous, M., Morey, A., Armes, J., Cummings, M. and Francis, G. (2004). CISH or FISH? The interlaboratory reproducibility of CISH testing for HER2 and correlation with IHC and FISH results. 4th European Breast Cancer Conference, Hamburg, Germany, 16–20 March 2004. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/S1359-6349(04)90763-X
Jass, J. R., Cummings, M. C., Simms, L. A., Walsh, M., Schoch, E., Meltzer, S. J., Wright, C., Searle, J., Young, J. P. and Leggett, B. A. (1999). Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator phenotypes. 11th Lorne Cancer Conference, Lorne, Victoria, Australia, 11th -14th February, 1999.
Karamatic, R., Donnan, K. D., Cummings, M. C., Winterford, C. M., Young, J. P., Leggett, B. A. and Radford-Smith, G. L. (1999). The effect of human bile and bile acids on duodenal epithelial cells. The Gastroenterological Society of Queensland, Coolum, Queensland, 12th - 14th June, 1999.
Wright, K., Walsh, M. D., Cummings, M. C. and Chenevix-Trench, G. (1999). The E-cadherin-catenin system in ovarian cancer. 11th Lorne Cancer Conference, Lorne, Victoria, Australia, 11th - 14th February, 1999. Amsterdam: Elsevier.