Journal Articles
Walker, Graeme J., Galbraith, Jack A., Baz, Betoul, Ferguson, Blake, Handoko, Herlina Y. and Khosrotehrani, Kiarash (2022). A murine Kitl allele regulates skin mast cell density across 58 collaborative mouse cross strains. Journal of Investigative Dermatology, 142 (8), 2275-2280.e4. doi: 10.1016/j.jid.2021.12.032
Boucher, Didier, Kariawasam, Ruvini, Burgess, Joshua, Gimenez, Adrian, Ocampo, Tristan E., Ferguson, Blake, Naqi, Ali, Walker, Graeme J., Bolderson, Emma, Gamsjaeger, Roland, O’Byrne, Kenneth J., Cubeddu, Liza, Khanna, Kum Kum and Richard, Derek J. (2021). hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage. Scientific Reports, 11 (1) 20256, 20256. doi: 10.1038/s41598-021-99355-0
Roy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702
Villani, Rehan M., Johnson, Ayaka, Galbraith, Jack A., Baz, Betoul, Handoko, Herlina Y., Walker, Graeme J. and Khosrotehrani, Kiarash (2020). Murine dorsal hair type is genetically determined by polymorphisms in candidate genes that influence BMP and WNT signalling. Experimental Dermatology, 29 (5) exd.14090, 450-461. doi: 10.1111/exd.14090
Chitsazan, Arash, Lambie, Duncan, Ferguson, Blake, Handoko, Herlina Y., Gabrielli, Brian, Walker, Graeme J. and Boyle, Glen M. (2020). Unexpected high levels of BRN2/POU3F2 expression in human dermal melanocytic nevi. Journal of Investigative Dermatology, 140 (6), 1299-1302.e4. doi: 10.1016/j.jid.2019.12.007
Ferguson, Blake, Handoko, Herlina Y., Mukhopadhyay, Pamela, Chitsazan, Arash, Balmer, Lois, Morahan, Grant and Walker, Graeme J. (2019). Different genetic mechanisms mediate spontaneous versus UVR-induced malignant melanoma. eLife, 8. doi: 10.7554/eLife.42424
Nicklin, James L., McGrath, Shaun, Tripcony, Lee, Garrett, Andrea, Land, Russell, Tang, Amy, Perrin, Lewis, Chetty, Naven, Jagasia, Nisha, Crandon, Alex J., Nascimento, Marcelo, Walker, Graeme, Sanday, Karen and Obermair, Andreas (2017). The shift toward neo-adjuvant chemotherapy and interval debulking surgery for management of advanced ovarian and related cancers in a population-based setting: Impact on clinical outcomes. Australian & New Zealand Journal of Obstetrics and Gynaecology, 57 (6), 651-658. doi: 10.1111/ajo.12665
Janda, Monika, Gebski, Val, Davies, Lucy C., Forder, Peta, Brand, Alison, Hogg, Russell, Jobling, Thomas W., Land, Russell, Manolitsas, Tom, Nascimento, Marcelo, Neesham, Deborah, Nicklin, James L., Oehler, Martin K., Otton, Geoff, Perrin, Lewis, Salfinger, Stuart, Hammond, Ian, Leung, Yee, Sykes, Peter, Ngan, Hextan, Garrett, Andrea, Laney, Michael, Ng, Tong Yow, Tam, Karfai, Chan, Karen, Wrede, C. David, Pather, Selvan, Simcock, Bryony, Farrell, Rhonda ... Obermair, Andreas (2017). Effect of Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy on Disease-Free Survival Among Women With Stage I Endometrial Cancer A Randomized Clinical Trial. Jama-Journal of the American Medical Association, 317 (12), 1224-1233. doi: 10.1001/jama.2017.2068
Chitsazan, Arash, Ferguson, Blake, Ram, Ramesh, Mukhopadhyay, Pamela, Handoko, Herlina Y., Gabrielli, Brian, Soyer, Peter H, Morahan, Grant and Walker, Graeme J. (2016). A mutation in the Cdon gene potentiates congenital nevus development mediated by NRASQ61K. Pigment Cell and Melanoma Research, 29 (4), 459-464. doi: 10.1111/pcmr.12487
Rakic, Aleksandar, Karl Bertling, Yah Leng Lim, Wilson, Stephen J., Milan Nikolic, Thomas Taimre, Dragan Indjin, Alexander Valavanis, Edmund H. Linfield, A. Giles Davies, Graeme Walker, Blake Ferguson, Tarl Prow, Helmut Schaider and Soyer, H. Peter (2014). Biomedical applications of terahertz self-mixing interferometry. SPIE Newsroom doi: 10.1117/2.1201409.005613
Handoko, Herlina Y., Rodero, Mathieu P., Boyle, Glen M., Ferguson, Blake, Engwerda, Christian, Hill, Geoff, Muller, H. Konrad, Khosrotehrani, Kiarash and Walker, Graeme J. (2013). UVB-induced melanocyte proliferation in neonatal mice driven by CCR2-independent recruitment of Ly6c(low)MHCII(hi) macrophages. Journal of Investigative Dermatology, 133 (7), 1803-1812. doi: 10.1038/jid.2013.9
Wurm, Elisabeth M.T., Lin, Lynlee L., Ferguson, Blake, Lambie, Duncan, Prow, Tarl W., Walker, Graeme J. and Soyer, H. Peter (2012). A blueprint for staging of murine melanocytic lesions based on the Cdk4 R24C/R24C :: Tyr- NRAS Q 61K model. Experimental Dermatology, 21 (9), 676-681. doi: 10.1111/j.1600-0625.2012.01543.x
Walker, Graeme J., Soyer, H. P., Terzian, Tamara and Box, Neil F. (2011). Modelling melanoma in mice. Pigment Cell & Melanoma Research, 24 (6), 1158-1176. doi: 10.1111/j.1755-148X.2011.00923.x
Walker, Graeme J., Soyer, H. Peter, Handoko, Herlina Y., Ferguson, Blake, Kunisada, Takahiro, Khosrotehrani, Kiarash, Box, Neil F. and Muller, H. Konrad (2011). Superficial Spreading-Like Melanoma in Arf−/−::Tyr-NrasQ61K::K14-Kitl Mice: Keratinocyte Kit Ligand Expression Sufficient to “Translocate” Melanomas from Dermis to Epidermis. Journal of Investigative Dermatology, 131 (6), 1384-1387. doi: 10.1038/jid.2011.21
Ferguson, Blake, Muller, H. Konrad, Handoko, Herlina Y., Khosrotehrani, Kiarash, Beermann, Friedrich, Hacker, Elke, Soyer, H. Peter, Bosenberg, Marcus and Walker, Graeme J. (2010). Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis. Pigment Cell and Melanoma Research, 23 (6), 771-780. doi: 10.1111/j.1755-148X.2010.00752.x
Tonks, ID, Mould, AW, Schroder, WA, Hacker, E, Bosenberg, M, Hayward, NK, Walker, GJ and Kay, GF (2010). Melanocyte homeostasis in vivo tolerates Rb1 loss in a developmentally independent fashion. Pigment Cell and Melanoma Research, 23 (4), 564-570. doi: 10.1111/j.1755-148X.2010.00722.x
Hacker, E, Muller, HK, Hayward, N, Fahey, P and Walker, G (2010). Enhancement of DNA repair using topical T4 endonuclease V does not inhibit melanoma formation in Cdk4R24C⁄R24C⁄Tyr-NrasQ61K mice following neonatal UVR. Pigment Cell and Melanoma Research, 23 (1), 121-128. doi: 10.1111/j.1755-148X.2009.00643.x
Tonks, Ian D., Mould, Arne, Nurcombe, Victor, Cool, Simon M., Walker, Graeme J., Hacker, Elke, Keith, Patricia, Schroder, Wayne A., Cotterill, Andrew, Hayward, Nicholas K. and Kay, Graham F. (2009). Dual loss of Rb1 and Trp53 in melanocytes perturbs melanocyte homeostasis and genetic stability in vitro but does not cause melanoma or pigmentation defects in vivo. Pigment Cell and Melanoma Research, 22 (3), 328-330. doi: 10.1111/j.1755-148X.2009.00560.x
Walker, G.J., Kimlin, M.G., Hacker, E., Ravishankar, S., Muller, H.K., Beermann, F. and Hayward, N. K. (2009). Murine neonatal melanocytes exhibit a heightened proliferative response to ultraviolet radiation and migrate to the epidermal basal layer. Journal of Investigative Dermatology, 129 (1), 184-193. doi: 10.1038/jid.2008.210
Hacker, E., Muller, K., Whiteman, D. C., Pavey, S., Hayward, N. and Walker, G. (2008). Reduced expression of IL-18 is a marker of ultraviolet radiation-induced melanomas. International Journal of Cancer, 123 (1), 227-231. doi: 10.1002/ijc.23389
Pujana, M. A., Ruiz, A., Badenas, C., Puig-Butille, J-A., Nadal, M., Stark, M., Gomez, L., Valls, J., Sole, X., Hernandez, P., Cerrato, C., Madrigal, I., de Cid, R., Aguilar, H., Capella, G., Cal, S., James, M. R., Walker, G. J., Malvehy, J., Mila, M., Hayward, N. K., Estivill, X. and Puig, S. (2007). Molecular characterization of a t(9;12)(p21;q13) balanced chromosome translocation in combination with integrative genomics analysis identifies C9orf14 as a candidate tumor-suppressor. Genes, Chromosomes & Cancer, 46 (2), 155-162. doi: 10.1002/gcc.20396
Stark, M., Puig-Butille, J. A., Walker, G., Badenas, C., Malvehy, J., Hayward , N. and Puig, S. (2006). Mutation of the tumour suppressor p33ING1b is rare in melanoma. British Journal of Dermatology, 155 (1), 94-99. doi: 10.1111/j.1365-2133.2006.07274.x
Hacker, E., Muller, H. K., Irwin, N., Gabrielli, B., Lincoin, D., Pavey, S., Powell, M. B., Malumbres, M., Barbacid, M., Hayward, N. and Walker, G. (2006). Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4(R24C/R24C)/TPras mice. Cancer Research, 66 (6), 2946-2952. doi: 10.1158/0008-5472.CAN-05-3196
Tonks, Ian D., Hacker, Elke, Irwin, Nicole, Muller, H. Conrad, Keith, Patricia, Mould, Arne, Zournazi, Anna, Pavey, Sandra, Hayward, Nicholas K., Walker, Graeme and Kay, Graham F. (2005). Melanocytes in conditional Rb–/– mice are normal in vivo but exhibit proliferation and pigmentation defects in vitro. Pigment Cell and Melanoma Research, 18 (4), 252-264. doi: 10.1111/j.1600-0749.2005.00245.x
Young, Joanne, Simms, Lisa A., Barker, Melissa A., Walsh, Michael D., Biden, Kelli G., Buttenshaw, Ron, Whitehall, Vicki L.J., Arnold, Sven, Jackson, Leigh, Kambara, Takeshi, Spring, Kevin J., Jenkins, Mark A., Walker, Graeme J., Hopper, John L., Leggett, Barbara A. and Jass, Jeremy R. (2005). Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer. Clinical Gastroenterology and Hepatology, 3 (3), 254-263. doi: 10.1016/S1542-3565(04)00673-1
Walker, Graeme J., Indsto, James O., Sood, Raman, Faruque, Mezbah U., Hu, Ping, Pollock, Pam M., Duray, Paul, Holland, Elizabeth A., Brown, Kevin, Kefford, Richard F., Trent, Jeffrey M., Mann, Graham J. and Hayward, Nicholas K. (2004). Deletion mapping suggests that the 1p22 melanoma susceptibility gene is a tumor suppressor localized to a 9-Mb interval. Genes, Chromosomes & Cancer, 41 (1), 56-64. doi: 10.1002/gcc.20056
Pavey, Sandra, Johansson, Peter, Packer, Leisl, Taylor, Jennifer, Stark, Mitchell, Pollock, Pamela M., Walker, Graeme J., Boyle, Glen M., Harper, Ursula, Cozzi, Sarah-Jane, Hansen, Katherine, Yudt, Laura, Schmidt, Chris, Hersey, Peter, Ellem, Kay A. O., O'Rourke, Michael G. E., Parsons, Peter G., Meltzer, Paul, Ringnér, Markus and Hayward, Nicholas K. (2004). Microarray expression profiling in melanoma reveals a BRAF mutation signature. Oncogene, 23 (23), 4060-4067. doi: 10.1038/sj.onc.1207563
Pollock, P. M., Walker, G. J., Glendening, J. M., Noy, T. Q., Bloch, N. C., Fountain, J. W. and Hayward, N. K. (2002). PTEN inactivation is rare in melanoma tumours but occurs frequently in melanoma cell lines. Melanoma Research, 12 (6), 565-575. doi: 10.1097/00008390-200212000-00006
Walker, Graeme J. and Hayward, Nicholas K. (2002). Pathways to Melanoma Development: Lessons from the Mouse. Journal of Investigative Dermatology, 119 (4), 783-792. doi: 10.1046/j.1523-1747.2002.00217.x
Walker, Graeme J. and Hayward, Nicholas K. (2002). p16INK4A and p14ARF tumour suppressors in melanoma: lessons from the mouse. Lancet, 359 (9300), 7-8. doi: 10.1016/S0140-6736(02)07271-9
Conference Papers
Legrand, J., Muller, N., Baz, B., Morahan, G., Walker, G., Morrison, M. and Khosrotehrani, K. (2019). Skin bacterial composition is driven largely by host genetic background and polymorphisms regulating innate immunity. 49th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR), Bordeaux, France, 18-21 September 2019. New York, NY United States: Elsevier. doi: 10.1016/j.jid.2019.07.631
Khosrotehrani, K., Matigian, N., Baz, B., Legrand, J., Muller, N., Morrison, M. and Walker, G. (2018). Natural history of bacterial composition in skin wounds and its relationship to healing. International Investigative Dermatology (IID) Meeting, Orlando, FL United States, 16-19 May 2018. New York, NY United States: Elsevier.
Baz, B., Patel, J., Ram, R., Morahan, G., Walker, G. and Khosrotehrani, K. (2015). A Genome-wide Approach to Identify Determinants of Skin Wound Healing. 45th Annual Meeting of the European Society for Dermatological Research, Rotterdam, the Netherlands, 09-12 September 2015. London, United Kingdom: Nature Publishing Group. doi: 10.1038/jid.2015.271
Rakić, Aleksandar, Taimre, Thomas, Bertling, Karl, Lim, Yah Leng, Wilson, Stephen J., Nikolić, Milan, Valavanis, Alexander, Indjin, Dragan, Linfield, Edmund H., Davies, A. Giles, Ferguson, Blake, Walker, Graeme, Schaider, Helmut and Soyer, H. Peter (2014). THz QCL self-mixing interferometry for biomedical applications. SPIE Optical Engineering + Applications Conference 2014, San Diego, United States, 17-21 August 2014. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.2061433
Handoko, H. Y., Rodero, M., Walker, G. and Khosrotehrani, Ki (2011). The immune response influences melanocyte proliferation after ultraviolet radiation exposure. International Pigment Cell Conference (XXIst , IPCC, 2011), Bordeaux, France, 21-24 September 2011. Malden, MA, U.S.A.: Wiley-Blackwell Publishing. doi: 10.1111/j.1755-148X.2011.00885.x
Rodero, Mathieu, Handoko, Herlina, Walker, Graeme and Khosrotehrani, Kiarash (2011). Macrophages influence melanocyte proliferation after ultraviolet radiation exposure. Annual Meeting of the European Society for Dermatological Research (41st, ESDR, 2011), Barcelona, Spain, 7-10 September 2011. London, Hamps, U.K.: Nature Publishing Group. doi: 10.1038/jid.2011.214