Professor Di Yu
Professorial Research Fellow
Frazer Institute
Chair in Paediatric Immunotherapy
Child Health Research Centre
Professor Di Yu leads the Systems and translational immunology group.
Researcher biography
Professor Di Yu is a Chair in Paediatric Immunotherapy, Professor of Immunology, Director of Ian Frazer Centre of Children's Immunotherapy Research, and Head of Systems and Translational T-cell Immunology Laboratory (STTIL) at the University of Queensland. He earned his PhD from the Australian National University in 2007 and postdoctoral training at the Garvan Institute of Medical Research from 2008-2010. Before joining the University of Queensland, he was a faculty member at Monash University from 2011-2016 and at the Australian National University ANU from 2017-2019. His research focuses on exploring T cell subsets and developing new therapies to regulate their functions in clinical settings, with the goal of treating autoimmune diseases and cancer. He also leads the development and application of "systems immunology" techniques to evaluate individuals' immune status.
Professor Yu has authored over 100 publications of basic and translational research in immunology, including Nature, Nature Immunology, Nature Medicine, Immunity and Science Immunology, and is a Clarivate Highly Cited Researcher. In recognising his groundbreaking research, he has been elected as a Fellow of the Australian Academy of Health and Medical Sciences (FAHMS) and honoured with accolades such as the 2023 Jacques Miller Medal from the Australian Academy of Science (AAS), the 2021 Jian Zhou Medal from the Australian Academy of Health and Medical Sciences (AAHMS), and the inaugural 2021 AbbVie New Horizon Research Award from the Australia and New Zealand Society for Immunology (ASI), among others.
Book Chapters
Chen, Zhian, Liang, Kaili, Deng, Jun and Yu, Di (2022). Therapeutic modulation of T follicular helper cells by low-dose IL-2 treatment. T-follicular helper cells: methods and protocols. (pp. 255-265) New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-1736-6_21
Gao, Xin, Lin, Lin and Yu, Di (2018). Ex vivo culture assay to measure human follicular helper T (Tfh) cell-mediated human B cell proliferation and differentiation. Methods in bolecular biology. (pp. 111-119) New York, NY USA: Springer New York. doi: 10.1007/978-1-4939-7474-0_8
Yu, Di and Vinuesa, Carola G. (2009). Roquin defects reveal a role for the MicroRNA machinery in regulating autoimmunity. The Epigenetics of Autoimmune Diseases. (pp. 261-278) edited by Moncef Zouali. Chichester, West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/9780470743553.ch15
Journal Articles
Pazhouhandeh, Mehrdad and Yu, Di (2024). Interferon disrupts immune and tissue homeostasis in SLE via CXCL13. Nature Reviews Rheumatology. doi: 10.1038/s41584-024-01164-y
Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2024). Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 25 (9), 1764-1764. doi: 10.1038/s41590-024-01949-z
Patrick, Ralph, Naval-Sanchez, Marina, Deshpande, Nikita, Huang, Yifei, Zhang, Jingyu, Chen, Xiaoli, Yang, Ying, Tiwari, Kanupriya, Esmaeili, Mohammadhossein, Tran, Minh, Mohamed, Amin R., Wang, Binxu, Xia, Di, Ma, Jun, Bayliss, Jacqueline, Wong, Kahlia, Hun, Michael L., Sun, Xuan, Cao, Benjamin, Cottle, Denny L., Catterall, Tara, Barzilai-Tutsch, Hila, Troskie, Robin-Lee, Chen, Zhian, Wise, Andrea F., Saini, Sheetal, Soe, Ye Mon, Kumari, Snehlata, Sweet, Matthew J. ... Nefzger, Christian M. (2024). The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening. Cell Metabolism, 36 (8), 1858-1881.e23. doi: 10.1016/j.cmet.2024.06.006
Chen, Xin, Tsvetkov, Andrey S., Shen, Han-Ming, Isidoro, Ciro, Ktistakis, Nicholas T., Linkermann, Andreas, Koopman, Werner J. H., Simon, Hans-Uwe, Galluzzi, Lorenzo, Luo, Shouqing, Xu, Daqian, Gu, Wei, Peulen, Olivier, Cai, Qian, Rubinsztein, David C., Chi, Jen-Tsan, Zhang, Donna D., Li, Changfeng, Toyokuni, Shinya, Liu, Jinbao, Roh, Jong-Lyel, Dai, Enyong, Juhasz, Gabor, Liu, Wei, Zhang, Jianhua, Yang, Minghua, Liu, Jiao, Zhu, Ling-Qiang, Zou, Weiping ... Tang, Daolin (2024). International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis. Autophagy, 20 (6), 1213-1246. doi: 10.1080/15548627.2024.2319901
Li, Yanhong, Sang, Yifei, Chang, Yunjian, Xu, Chunfang, Lin, Yikong, Zhang, Yao, Chiu, Philip C.N., Yeung, William S.B., Zhou, Haisheng, Dong, Ningzheng, Xu, Ling, Chen, Jiajia, Zhao, Weijie, Liu, Lu, Yu, Di, Zang, Xingxing, Ye, Jiangfeng, Yang, Jinying, Wu, Qingyu, Li, Dajin, Wu, Ligang and Du, Meirong (2024). A Galectin-9–Driven CD11c
high
Decidual Macrophage Subset Suppresses Uterine Vascular Remodeling in Preeclampsia. Circulation, 149 (21), 1670-1688. doi: 10.1161/circulationaha.123.064391
Ye, Tong, Jiao, Zhouguang, Li, Xin, He, Zhanlong, Li, Yanyan, Yang, Fengmei, Zhao, Xin, Wang, Youchun, Huang, Weijin, Qin, Meng, Feng, Yingmei, Qiu, Yefeng, Yang, Wenhui, Hu, Lingfei, Hu, Yaling, Zhai, Yu, Wang, Erqiang, Yu, Di, Wang, Shuang, Yue, Hua, Wang, Yishu, Wang, Hengliang, Zhu, Li, Ma, Guanghui and Wei, Wei (2023). Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization. Nature, 624 (7992), 630-638. doi: 10.1038/s41586-023-06809-8
Nettelfield, Sam, Yu, Di and Cañete, Pablo F (2023). Systemic immunometabolism and responses to vaccines: insights from T and B cell perspectives. International Immunology, 35 (12), 571-582. doi: 10.1093/intimm/dxad021
Yuan, Lin, Xie, Lei, Zhang, Hao, Zhang, Yu, Wei, Yunbo, Feng, Jinhong, Cui, Li, Tian, Rui, Feng, Jia, Yu, Di and Lv, Cui (2023). Low-dose IL-2 treatment rescues cognitive deficits by repairing the imbalance between Treg and Th17 cells at the middle Alzheimer’s disease stage. Journal of Neuroimmune Pharmacology, 18 (4), 674-689. doi: 10.1007/s11481-023-10090-x
Kang, Hao, Sun, Hongjian, Yang, Yang, Tuong, Zewen K., Shu, Minglei, Wei, Yunbo, Zhang, Yu, Yu, Di and Tao, Yong (2023). Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality. Clinical and Translational Immunology, 12 (9) e1461, 1-17. doi: 10.1002/cti2.1461
Yunis, Joseph, Short, Kirsty R. and Yu, Di (2023). Severe respiratory viral infections: T-cell functions diverging from immunity to inflammation. Trends in Microbiology, 31 (6), 644-656. doi: 10.1016/j.tim.2022.12.008
Chen, Titi, Cao, Qi, Wang, Ruifeng, Zheng, Guoping, Azmi, Farhana, Lee, Vincent W., Wang, Yuan Ming, Li, Hongqi, Yu, Di, Rogers, Natasha M., Alexander, Stephen I., Harris, David C.H. and Wang, Yiping (2023). Attenuation of renal injury by depleting cDC1 and by repurposing Flt3 inhibitor in anti-GBM disease. Clinical Immunology, 250 109295, 1-14. doi: 10.1016/j.clim.2023.109295
Chen, Zhian, Cui, Yanfang, Yao, Yin, Liu, Bo, Yunis, Joseph, Gao, Xin, Wang, Naiqi, Cañete, Pablo F., Tuong, Zewen Kelvin, Sun, Hongjian, Wang, Hao, Yang, Siling, Wang, Runli, Leong, Yew Ann, Simon Davis, David, Qin, Jiahuan, Liang, Kaili, Deng, Jun, Wang, Conan K., Huang, Yen-Hua, Roco, Jonathan A., Nettelfield, Sam, Zhu, Huaming, Xu, Huajun, Yu, Zhijia, Craik, David, Liu, Zheng, Qi, Hai, Parish, Christopher and Yu, Di (2023). Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology, 8 (80) eadd1728, 1-17. doi: 10.1126/sciimmunol.add1728
Gao, Xin, Luo, Kaiming, Wang, Diya, Wei, Yunbo, Yao, Yin, Deng, Jun, Yang, Yang, Zeng, Qunxiong, Dong, Xiaoru, Xiong, Le, Gong, Dongcheng, Lin, Lin, Pohl, Kai, Liu, Shaoling, Liu, Yu, Liu, Lu, Nguyen, Thi HO, Allen, Lilith F., Kedzierska, Katherine, Jin, Yanliang, Du, Mei-Rong, Chen, Wanping, Lu, Liangjing, Shen, Nan, Liu, Zheng, Cockburn, Ian A., Luo, Wenjing and Yu, Di (2023). T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance. eLife, 12 e82217, 1-29. doi: 10.7554/elife.82217
Yang, Yang, Tuong, Zewen K. and Yu, Di (2023). Dimensionality reduction under scrutiny. Nature Computational Science, 3 (1), 8-9. doi: 10.1038/s43588-022-00383-1
Gong, Huanle, Ma, Shoubao, Chen, Jia, Yang, Bingyu, Liu, Shuangzhu, Liu, Xin, Han, Jingjing, Wu, Xiaojin, Lei, Lei, Yin, Zhinan, Sun, Hongjian, Yu, Di, Liu, Haiyan, Xu, Yang and Wu, Depei (2022). Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease. Signal Transduction and Targeted Therapy, 7 (1) 319, 1-12. doi: 10.1038/s41392-022-01147-z
Liu, Limin, Hu, Longyuan, Long, Haojun, Zheng, Meiling, Hu, Zhi, He, Ye, Gao, Xiaofei, Du, Pei, Zhao, Hongjun, Yu, Di, Lu, Qianjin and Zhao, Ming (2022). LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus. Clinical and Translational Medicine, 12 (12) e1117, 1-21. doi: 10.1002/ctm2.1117
He, Jing, Chen, Jiali, Miao, Miao, Zhang, Ruijun, Cheng, Gong, Wang, Yifan, Feng, Ruiling, Huang, Bo, Luan, Huijie, Jia, Yuan, Jin, Yuebo, Zhang, Xiaoying, Shao, Miao, Wang, Yu, Zhang, Xia, Li, Jing, Zhao, Xiaozhen, Wang, Han, Liu, Tian, Xiao, Xian, Zhang, Xuewu, Su, Yin, Mu, Rong, Ye, Hua, Li, Ru, Liu, Xu, Liu, Yanying, Li, Chun, Liu, Huixin ... Li, Zhanguo (2022). Efficacy and Safety of Low-Dose Interleukin 2 for Primary Sjögren Syndrome: A Randomized Clinical Trial. JAMA Network Open, 5 (11) e2241451, 1-16. doi: 10.1001/jamanetworkopen.2022.41451
Yao, Yin, Huang, Ao, Deng, Yi-Ke, Liu, Yan, Zhu, Hong-Yu, Wang, Nan, Wang, Zhe-Zheng, Zhu, Rong-Fei, Yu, Di and Liu, Zheng (2022). Allergen Immunotherapy Reverses Immune Response to SARS-CoV-2 Vaccine in Patients with Allergic Rhinitis: A Prospective Observational Trial. American Journal of Respiratory and Critical Care Medicine, 206 (6), 780-783. doi: 10.1164/rccm.202203-0608le
Zhang, Lei, Jiang, Li, Yu, Liang, Li, Qin, Tian, Xiangjun, He, Jingquan, Zeng, Ling, Yang, Yuqin, Wang, Chaoran, Wei, Yuhan, Jiang, Xiaoyue, Li, Jing, Ge, Xiaolu, Gu, Qisheng, Li, Jikun, Wu, Di, Sadler, Anthony J., Yu, Di, Xu, Dakang, Gao, Yue, Yuan, Xiangliang and He, Baokun (2022). Inhibition of UBA6 by inosine augments tumour immunogenicity and responses. Nature Communications, 13 (1) 5413, 1-16. doi: 10.1038/s41467-022-33116-z
Yu, Di, Walker, Lucy S. K., Liu, Zheng, Linterman, Michelle A. and Li, Zhanguo (2022). Targeting TFH cells in human diseases and vaccination: rationale and practice. Nature Immunology, 23 (8), 1157-1168. doi: 10.1038/s41590-022-01253-8
Gong, Jialei, Wang, Peng, Liu, Jin-Chuan, Li, Jianlin, Zeng, Qun-Xiong, Yang, Chen, Li, Yanfeng, Yu, Di, Cao, Dandan and Duan, Yong-Gang (2022). Integrative analysis of small RNA and mRNA expression profiles identifies signatures associated with chronic epididymitis. Frontiers in Immunology, 13 883803, 1-12. doi: 10.3389/fimmu.2022.883803
Gao, Xiaofei, Song, Yang, Wu, Jiali, Lu, Shuang, Min, Xiaoli, Liu, Limin, Hu, Longyuan, Zheng, Meiling, Du, Pei, Yu, Yaqin, Long, Hai, Wu, Haijing, Jia, Sujie, Yu, Di, Lu, Qianjin and Zhao, Ming (2022). Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus. Journal of Clinical Investigation, 132 (9) e152345. doi: 10.1172/JCI152345
Chen, Zhian, Wang, Naiqi, Yao, Yin and Yu, Di (2022). Context-dependent regulation of follicular helper T cell survival. Trends in Immunology, 43 (4), 309-321. doi: 10.1016/j.it.2022.02.002
Wang, Zhi-Chao, Yao, Yin, Chen, Cai-Ling, Guo, Cui-Lian, Ding, Hong-Xia, Song, Jia, Wang, Zhe-Zheng, Wang, Nan, Li, Xue-Li, Liao, Bo, Yang, Yang, Yu, Di and Liu, Zheng (2022). Extrafollicular PD-1highCXCR5–CD4+ T cells participate in local immunoglobulin production in nasal polyps. Journal of Allergy and Clinical Immunology, 149 (2), 610-623. doi: 10.1016/j.jaci.2021.06.023
Chen, Zhian, Gao, Xin and Yu, Di (2022). Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy. View, 3 (1) 20200103, 20200103. doi: 10.1002/viw.20200103
Yao, Yin, Wang, Zhe-Zheng, Huang, Ao, Liu, Yan, Wang, Nan, Wang, Zhi-Chao, Yang, Lin, Li, Hui-Jun, Xie, Jun-Gang, Zhu, Rong-Fei, Cheng, Li-Ming, Yu, Di and Liu, Zheng (2022). TFH2 cells associate with enhanced humoral immunity to SARS-CoV-2 inactivated vaccine in patients with allergic rhinitis. Clinical and Translational Medicine, 12 (1) e717, e717. doi: 10.1002/ctm2.717
Antczak, Magdalena, Cañete, Pablo F., Chen, Zhian, Belle, Clémence and Yu, Di (2022). Evolution of γ chain cytokines: mechanisms, methods and applications. Computational and Structural Biotechnology Journal, 20, 4746-4755. doi: 10.1016/j.csbj.2022.08.050
Kang, Hao, Wei, Yunbo, Liu, Ming, Yu, Di and Tao, Yong (2021). Flow cytometric analysis of T lymphocytes and cytokines in aqueous humor of patients with varicella zoster virus-mediated acute retinal necrosis. BMC Ophthalmology, 21 (1) 193. doi: 10.1186/s12886-021-01951-1
Wang, Shuang, Li, Feng, Ye, Tong, Wang, Jianghua, Lyu, Chengliang, Qing, Shuang, Ding, Zhaowen, Gao, Xiaoyong, Jia, Rongrong, Yu, Di, Ren, Jun, Wei, Wei and Ma, Guanghui (2021). Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment. Science Translational Medicine, 13 (615) eabb6981, eabb6981. doi: 10.1126/scitranslmed.abb6981
Yu, Di, Guo, Zhangke, You, Xin, Peng, Wei, Qi, Jirong, Sun, Jian, Wu, Kaihong, Li, Xiaofeng and Mo, Xuming (2021). Long-term outcomes in children undergoing vascular ring division: a multi-institution experience. European Journal of Cardio-Thoracic Surgery, 61 (3), 605-613. doi: 10.1093/ejcts/ezab432
Puri, Prianka, Jiang, Simon H., Yang, Yang, Mackay, Fabienne and Yu, Di (2021). Understand SLE heterogeneity in the era of omics, big data, and artificial intelligence. Rheumatology and Autoimmunity, 1 (1), 38-49. doi: 10.1002/rai2.12010
Zhou, Pengcheng, Chen, Jiali, He, Jing, Zheng, Ting, Yunis, Joseph, Makota, Victor, Alexandre, Yannick O., Gong, Fang, Zhang, Xia, Xie, Wuxiang, Li, Yuhui, Shao, Miao, Zhu, Yanshan, Sinclair, Jane E., Miao, Miao, Chen, Yaping, Short, Kirsty R., Mueller, Scott N., Sun, Xiaolin, Yu, Di and Li, Zhanguo (2021). Low-dose IL-2 therapy invigorates CD8+ T cells for viral control in systemic lupus erythematosus with a potential risk of deteriorating immunopathology. PLoS Pathogens, 17 (10) e1009858, e1009858. doi: 10.1371/journal.ppat.1009858
Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2021). Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 22 (12), 1599-1599. doi: 10.1038/s41590-021-01063-4
Qin, Jiahuan, Huang, Xia, Wang, Naiqi, Zhou, Pengcheng, Zhang, Hao, Chen, Zhian, Liang, Kaili, Gong, Dongcheng, Zeng, Qunxiong, Niu, Peng, Chen, Anping, Yuan, Lin, Yang, Zhaohui, Su, Linchong, Shen, Nan, Deng, Jun and Yu, Di (2021). Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4
+
T cells and ameliorates rheumatoid arthritis. Clinical & Translational Immunology, 10 (9) e1338, e1338. doi: 10.1002/cti2.1338
Zheng, Ting, Fan, Miao, Wei, Yunbo, Feng, Jinhong, Zhou, Pengcheng, Sun, Xin, Xue, Anqi, Qin, Cheng Xue and Yu, Di (2021). Huangbai liniment ameliorates skin inflammation in atopic dermatitis. Frontiers in Pharmacology, 12 726035, 726035. doi: 10.3389/fphar.2021.726035
Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2021). Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 22 (9), 1127-1139. doi: 10.1038/s41590-021-00996-0
Yang, Yang, Sun, Hongjian, Zhang, Yu, Zhang, Tiefu, Gong, Jialei, Wei, Yunbo, Duan, Yong-Gang, Shu, Minglei, Yang, Yuchen, Wu, Di and Yu, Di (2021). Dimensionality reduction by UMAP reinforces sample heterogeneity analysis in bulk transcriptomic data. Cell Reports, 36 (4) 109442, 109442. doi: 10.1016/j.celrep.2021.109442
Tian, Ying, Zhang, Fan, Qiu, Yefeng, Wang, Shuang, Li, Feng, Zhao, Jiawei, Pan, Chao, Tao, Yong, Yu, Di and Wei, Wei (2021). Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells. Nature Biomedical Engineering, 5 (9), 968-982. doi: 10.1038/s41551-021-00764-3
Tyllis, Timona S., Fenix, Kevin A., Norton, Todd S., Kara, Ervin E., McKenzie, Duncan R., David, Shannon C., Alsharifi, Mohammed, Yu, Di, McColl, Shaun R. and Comerford, Iain (2021). CXCR5+CD8+ T cells shape antibody responses in vivo following protein immunisation and peripheral viral infection. Frontiers in Immunology, 12 626199, 626199. doi: 10.3389/fimmu.2021.626199
Xie, Liang, McKenzie, Craig I., Qu, Xinyan, Mu, Yan, Wang, Quanbo, Bing, Nan, Naidoo, Karmella, Alam, Md Jahangir, Yu, Di, Gong, Fang, Ang, Caroline, Robert, Remy, Marques, Francine Z., Furlotte, Nicholas, Hinds, David, Gasser, Olivier, Xavier, Ramnik J., MacKay, Charles R., Agee, Michelle, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McCreight, Jennifer C., McIntyre, Matthew H. ... 23andMe Research Team (2021). PH and proton sensor GPR65 determine susceptibility to atopic dermatitis. Journal of Immunology, 207 (1), 101-109. doi: 10.4049/jimmunol.2001363
Liang, Kaili, He, Jing, Wei, Yunbo, Zeng, Qunxiong, Gong, Dongcheng, Qin, Jiahuan, Ding, Huihua, Chen, Zhian, Zhou, Ping, Niu, Peng, Chen, Qian, Ding, Chenguang, Lu, Liangjing, Chen, Xiao-Xiang, Li, Zhanguo, Shen, Nan, Yu, Di and Deng, Jun (2021). Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus. Clinical and Translational Immunology, 10 (6) e1293, e1293. doi: 10.1002/cti2.1293
Deng, Jun, Chen, Qian, Chen, Zhian, Liang, Kaili, Gao, Xin, Wang, Xiaohui, Makota, Fadzai V., Ong, Hong Sheng, Wan, Yanmin, Luo, Kaiming, Gong, Dongcheng, Yu, Xiang, Camuglia, Sarina, Zeng, Qunxiong, Zhou, Tao, Xue, Feng, He, Jing, Wei, Yunbo, Xiao, Fan, Ma, Jianyang, Hill, Danika L., Pierson, Wim, Nguyen, Thi H. O., Zhou, Haibo, Wang, Yan, Shen, Wei, Sun, Lingyun, Li, Zhanguo, Xia, Qiang ... Yu, Di (2021). The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses. Nature Communications, 12 (1) 3073, 3073. doi: 10.1038/s41467-021-23220-x
Wang, Hai, Hu, Dan-Qing, Xiao, Qiao, Liu, Yi-Bo, Song, Jia, Liang, Yuxia, Ruan, Jian-Wen, Wang, Zhe-Zheng, Li, Jing-Xian, Pan, Li, Wang, Meng-Chen, Zeng, Ming, Shi, Li-Li, Xu, Kai, Ning, Qin, Zhen, Guohua, Yu, Di, Wang, De-Yun, Wenzel, Sally E. and Liu, Zheng (2021). Defective STING expression potentiates IL-13 signaling in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps. Journal of Allergy and Clinical Immunology, 147 (5), 1692-1703. doi: 10.1016/j.jaci.2020.12.623
Tan, Qiyue, Lv, Yuebin, Zhao, Feng, Zhou, Jinhui, Yang, Yang, Liu, Yingchun, Zhang, Mingyuan, Lu, Feng, Wei, Yuan, Chen, Xin, Zhang, Ruizhi, Chen, Chen, Wu, Bing, Zhang, Xiaochang, Li, Chengcheng, Huang, Hongyuan, Cai, Junfang, Cao, Zhaojin, Yu, Di, Ji, John S., Zhao, Shuhua and Shi, Xiaoming (2021). Association of low blood arsenic exposure with level of malondialdehyde among Chinese adults aged 65 and older. Science of the Total Environment, 758 143638, 1-8. doi: 10.1016/j.scitotenv.2020.143638
Yao, Yin, Chen, Cai-Ling, Yu, Di and Liu, Zheng (2021). Roles of follicular helper and regulatory T cells in allergic diseases and allergen immunotherapy. Allergy, 76 (2), 456-470. doi: 10.1111/all.14639
Xie, Min, Yunis, Joseph, Yao, Yin, Shi, Jing, Yang, Yang, Zhou, Pengcheng, Liang, Kaili, Wan, Yanmin, Mehdi, Ahmed, Chen, Zhian, Wang, Naiqi, Xu, Shuyun, Zhou, Min, Yu, Muqing, Wang, Ke, Tao, Yu, Zhou, Ying, Li, Xiaochen, Liu, Xiansheng, Yu, Xiao, Wei, Yunbo, Liu, Zheng, Sprent, Jonathan and Yu, Di (2021). High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses. Clinical & Translational Immunology, 10 (2) e1251, e1251. doi: 10.1002/cti2.1251
Gong, Jialei, Zeng, Qunxiong, Yu, Di and Duan, Yong-Gang (2021). T lymphocytes and testicular immunity: a new insight into immune regulation in testes. International Journal of Molecular Sciences, 22 (1) 57, 1-21. doi: 10.3390/ijms22010057
Zhou, Pengcheng, Zheng, Ting, Li, Yunping, Zhang, Xin, Feng, Jinhong, Wei, Yunbo, Wang, Hao, Yao, Yin, Gong, Fang, Tian, Wenjing, Sun, Lingyun, Liu, Zheng, Zhao, Bin and Yu, Di (2020). Chlorinated flame-retardant dechlorane 602 potentiates type 2 innate lymphoid cells and exacerbates airway inflammation. Environmental Science and Technology, 55 (2) acs.est.0c03758, 1099-1109. doi: 10.1021/acs.est.0c03758
Lv, Cui, Zhang, Hao, Li, Zifa, Zhang, Hao, Zhang, Yu, Li, Ronghui, Wei, Sheng and Yu, Di (2020). Low-dose IL-2 therapy compensates for metabolic shifts and reverses anxiety-like behavior in PD-1 deficiency-induced autoimmunity. Cellular and Molecular Immunology, 18 (5), 1336-1338. doi: 10.1038/s41423-020-00562-y
Ratnayake, Gishan, Reinwald, Simone, Shackleton, Mark, Moore, Maggie, Voskoboynik, Mark, Ruben, Jeremy, van Zelm, Menno C., Yu, Di, Ward, Rachel, Smith, Robin, Haydon, Andrew and Senthi, Sashendra (2020). Stereotactic Radiation Therapy Combined With Immunotherapy Against Metastatic Melanoma: Long-Term Results of a Phase 1 Clinical Trial. International Journal of Radiation Oncology Biology Physics, 108 (1), 150-156. doi: 10.1016/j.ijrobp.2020.05.022
Gong, Fang, Dai, Yaping, Zheng, Ting, Cheng, Liang, Zhao, Dan, Wang, Hao, Liu, Min, Pei, Hao, Jin, Tengchuan, Yu, Di and Zhou, Pengcheng (2020). Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals. Journal of Clinical Investigation, 130 (12), 6588-6599. doi: 10.1172/jci141054
Yao, Yin, Wang, Nan, Chen, Cai-Ling, Pan, Li, Wang, Zhi-Chao, Yunis, Joseph, Chen, Zhi-An, Zhang, Yu, Hu, Si-Tao, Xu, Xiao-Yan, Zhu, Rong-Fei, Yu, Di and Liu, Zheng (2020). CD23 expression on switched memory B cells bridges T-B cell interaction in allergic rhinitis. Allergy, 75 (10), 1-14. doi: 10.1111/all.14288
Yi, Shuhua, Zhang, Yu, Xiong, Wenjie, Chen, Weiwei, Hou, Zhaohua, Yang, Yang, Yan, Yuting, Wei, Yunbo, Cui, Rui, Wang, Huijun, Yu, Zhen, Li, Heng, Li, Zengjun, Liu, Wei, Lv, Rui, Wang, Tingyu, Ru, Kun, Zou, Dehui, Shu, Minglei, Qiu, Lugui and Yu, Di (2020). Prominent immune signatures of T cells are specifically associated with indolent B-cell lymphoproliferative disorders and predict prognosis. Clinical and Translational Immunology, 9 (1) e01105. doi: 10.1002/cti2.1105
Shao, Feng, Zheng, Peilin, Yu, Di, Zhou, Zhiguang and Jia, Lijing (2020). Follicular helper T cells in type 1 diabetes. The FASEB Journal, 34 (1), 30-40. doi: 10.1096/fj.201901637R
He, Jing, Zhang, Ruijun, Shao, Miao, Zhao, Xiaozhen, Miao, Miao, Chen, Jiali, Liu, Jiajia, Zhang, Xiaoying, Zhang, Xia, Jin, Yuebo, Wang, Yu, Zhang, Shilei, Zhu, Lei, Jacob, Alexander, Jia, Rulin, You, Xujie, Li, Xue, Li, Chun, Zhou, Yunshan, Yang, Yue, Ye, Hua, Liu, Yanying, Su, Yin, Shen, Nan, Alexander, Jessy, Guo, Jianping, Ambrus, Julian, Lin, Xin, Yu, Di ... Li, Zhanguo (2020). Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial. Annals of the Rheumatic Diseases, 79 (1), 141-149. doi: 10.1136/annrheumdis-2019-215396
Gao, Xin, Wang, Hao, Chen, Zhian, Zhou, Pengcheng and Yu, Di (2019). An optimized method to differentiate mouse follicular helper T cells in vitro. Cellular and Molecular Immunology, 17 (7), 779-781. doi: 10.1038/s41423-019-0329-7
Wang, Huimeng, Kjer-Nielsen, Lars, Shi, Mai, D'Souza, Criselle, Pediongco, Troi J., Cao, Hanwei, Kostenko, Lyudmila, Lim, Xin Yi, Eckle, Sidonia B. G., Meehan, Bronwyn S., Zhu, Tianyuan, Wang, Bingjie, Zhao, Zhe, Mak, Jeffrey Y. W., Fairlie, David P., Teng, Michele W. L., Rossjohn, Jamie, Yu, Di, de St Groth, Barbara Fazekas, Lovrecz, George, Lu, Louis, McCluskey, James, Strugnell, Richard A., Corbett, Alexandra J. and Chen, Zhenjun (2019). IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection. Science Immunology, 4 (41) eaaw0402, eaaw0402. doi: 10.1126/sciimmunol.aaw0402
Zhou, Pengcheng, Liang, Kaili and Yu, Di (2019). Germinal center T-FH cells: T(w)o be or not t(w)o be, IL-6 is the answer. Science Immunology, 4 (39) eaay7668, eaay7668. doi: 10.1126/sciimmunol.aay7668
Jiang, Mengjie, Fan, Jinjin, Qu, Xinli, Li, Songhui, Nilsson, Susan K., Sun, Yu Bo Yang, Chen, Yaping, Yu, Di, Liu, Dan, Liu, Bi-Cheng, Tang, Mingliang, Chen, Wei, Ren, Yi, Nikolic-Paterson, David J., Jiang, Xiaoyun, Li, Jinhua and Yu, Xueqing (2019). Combined blockade of Smad3 and JNK pathways ameliorates progressive fibrosis in folic acid nephropathy. Frontiers in Pharmacology, 10 (JULY) ARTN 880. doi: 10.3389/fphar.2019.00880
Deng, Jun, Wei, Yunbo, Fonseca, Valter R., Graca, Luis and Yu, Di (2019). T follicular helper cells and T follicular regulatory cells in rheumatic diseases. Nature Reviews Rheumatology, 15 (8), 475-490. doi: 10.1038/s41584-019-0254-2
Yao, Yin, Wang, Zhi-Chao, Wang, Nan, Zhou, Peng-Cheng, Chen, Cai-Ling, Song, Jia, Pan, Li, Liao, Bo, Zhang, Xin-Hao, Yang, Yong-Shi, Xu, Xiao-Yan, Zhu, Rong-Fei, Yu, Di and Liu, Zheng (2019). Allergen immunotherapy improves defective follicular regulatory T cells in patients with allergic rhinitis. Journal of Allergy and Clinical Immunology, 144 (1), 118-128. doi: 10.1016/j.jaci.2019.02.008
Wiede, Florian, Brodnicki, Thomas C., Goh, Pei Kee, Leong, Yew A., Jones, Gareth W., Yu, Di, Baxter, Alan G., Jones, Simon A., Kay, Thomas W.H. and Tiganis, Tony (2019). T-cell–specific PTPN2 deficiency in NOD mice accelerates the development of type 1 diabetes and autoimmune comorbidities. Diabetes, 68 (6), 1251-1266. doi: 10.2337/db18-1362
Liang, Yichen, Yao, Yang, Zhang, Ruijun, Shao, Miao, Sun, Xiaolin, Shi, Guixiu, Gao, Chun, Yu, Di and He, Jing (2019). Role of circulating T follicular helper subsets and T follicular helper effector memory cells in systemic lupus erythematosus 外周血效应型滤泡辅助性T细胞和滤泡辅助性T细胞亚型在系统性红斑狼疮发病机制中的作用. National Medical Journal of China, 99 (3), 164-168. doi: 10.3760/cma.j.issn.0376-2491.2019.03.002
Wu, Ning, Sun, Erwei, Liu, Dongfang and Yu, Di (2019). Tissue-Specific Immunity in Homeostasis and Diseases. Journal of Immunology Research, 2019 7616509, 1-2. doi: 10.1155/2019/7616509
Yu, Di and Ye, Lilin (2018). A portrait of CXCR5(+) follicular cytotoxic CD8(+) T cells. Trends in Immunology, 39 (12), 965-979. doi: 10.1016/j.it.2018.10.002
Yao, Yin, Wang, Zhi-Chao, Yu, Di and Liu, Zheng (2018). Role of allergen-specific T-follicular helper cells in immunotherapy. Current Opinion in Allergy and Clinical Immunology, 18 (6), 495-501. doi: 10.1097/aci.0000000000000480
Yao, Yin, Chen, Cai-Ling, Wang, Nan, Wang, Zhi-Chao, Ma, Jin, Zhu, Rong-Fei, Xu, Xiao-Yan, Zhou, Peng-Cheng, Yu, Di and Liu, Zheng (2018). Correlation of allergen-specific T follicular helper cell counts with specific IgE levels and efficacy of allergen immunotherapy. Journal of Allergy and Clinical Immunology, 142 (1), 321-324. doi: 10.1016/j.jaci.2018.03.008
Deng, Jun, Fan, Chaofan, Gao, Xin, Zeng, Qunxiong, Guo, Ruru, Wei, Yunbo, Chen, Zhian, Chen, Yanan, Gong, Dongcheng, Feng, Jia, Xia, Yan, Xiang, Shifei, Gong, Shushi, Yuan, Lin, Shen, Wei, Shen, Wenyan, Lin, Lin, Jiang, Ting, He, Dongyi, Lu, Liangjing, Chen, Xiaoxiang and Yu, Di (2018). Signal transducer and activator of transcription 3 hyperactivation associates with follicular helper T cell differentiation and disease activity in rheumatoid arthritis. Frontiers in Immunology, 9 (JUN) 1226, 1-11. doi: 10.3389/fimmu.2018.01226
Cao, Qi, Wang, Yiping, Niu, Zhiguo, Wang, Chengshi, Wang, Ruifeng, Zhang, Zhiqiang, Chen, Titi, Wang, Xin Maggie, Li, Qing, Lee, Vincent W. S., Huang, Qingsong, Tan, Jing, Guo, Minghao, Wang, Yuan Min, Zheng, Guoping, Yu, Di, Alexander, Stephen I., Wang, Hui and Harris, David C. H. (2018). Potentiating tissue-resident type 2 innate lymphoid cells by IL-33 to prevent renal ischemia-reperfusion injury. Journal of the American Society of Nephrology, 29 (3), 961-976. doi: 10.1681/ASN.2017070774
Mei, Longcan, Zhou, Yanping, Zhu, Lizhe, Liu, Changlin, Wu, Zhuo, Wang, Fangkui, Hao, Gefei, Yu, Di, Yuan, Hong and Cui, Yanfang (2018). Site-mutation of hydrophobic core residues synchronically poise super interleukin 2 for signaling: identifying distant structural effects through affordable computations. International Journal of Molecular Sciences, 19 (3) 916, 916. doi: 10.3390/ijms19030916
Song, Jia, Wang, Hai, Zhang, Ya-Na, Cao, Ping-Ping, Liao, Bo, Wang, Zhe-Zheng, Shi, Li-Li, Yao, Yin, Zhai, Guan-Ting, Wang, Zhi-Chao, Liu, Li-Meng, Zeng, Ming, Lu, Xiang, Wang, Heng, Yang, Xiang-Ping, Yu, Di, Bachert, Claus and Liu, Zheng (2018). Ectopic lymphoid tissues support local immunoglobulin production in patients with chronic rhinosinusitis with nasal polyps. Journal of Allergy and Clinical Immunology, 141 (3), 927-937. doi: 10.1016/j.jaci.2017.10.014
Xu, Shan, Zhou, Yanping, Geng, Hui, Song, Dandan, Tang, Jing, Zhu, Xianmin, Yu, Di, Hu, Sheng and Cui, Yanfang (2017). Serum metabolic profile alteration reveals response to platinum-based combination chemotherapy for lung cancer: sensitive patients distinguished from insensitive ones. Scientific Reports, 7 (1) 17524. doi: 10.1038/s41598-017-16085-y
Ni, Dezhi, Qing, Shuang, Ding, Hui, Yue, Hua, Yu, Di, Wang, Shuang, Luo, Nana, Su, Zhiguo, Wei, Wei and Ma, Guanghui (2017). Biomimetically engineered demi-bacteria potentiate vaccination against cancer. Advanced Science, 4 (10), 1700083. doi: 10.1002/advs.201700083
Li, Zhanguo, He, Jing and Yu, Di (2017). The rise of IL-2 therapy - a picture beyond T-reg cells. Nature Reviews. Rheumatology, 13 (6), 386-386. doi: 10.1038/nrrheum.2017.70
Leong, Yew Ann, Atnerkar, Anurag and Yu, Di (2017). Human immunodeficiency virus Playing Hide-and-Seek: Understanding the T-FH Cell Reservoir and Proposing Strategies to Overcome the Follicle Sanctuary. Frontiers in Immunology, 8 (MAY) 622. doi: 10.3389/fimmu.2017.00622
Wiede, Florian, Sacirbegovic, Faruk, Leong, Yew Ann, Yu, Di and Tiganis, Tony (2017). PTPN2-deficiency exacerbates T follicular helper cell and B cell responses and promotes the development of autoimmunity. Journal of Autoimmunity, 76, 85-100. doi: 10.1016/j.jaut.2016.09.004
Leong, Yew Ann, Chen, Yaping, Ong, Hong Sheng, Wu, Di, Man, Kevin, Deleage, Claire, Minnich, Martina, Meckiff, Benjamin J., Wei, Yunbo, Hou, Zhaohua, Zotos, Dimitra, Fenix, Kevin A., Atnerkar, Anurag, Preston, Simon, Chipman, Jeffrey G., Beilman, Greg J., Allison, Cody C., Sun, Lei, Wang, Peng, Xu, Jiawei, Toe, Jesse G., Lu, Hao K., Tao, Yong, Palendira, Umaimainthan, Dent, Alexander L., Landay, Alan L., Pellegrini, Marc, Comerford, Iain, McColl, Shaun R. ... Yu, Di (2016). CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles. Nature Immunology, 17 (10), 1187-+. doi: 10.1038/ni.3543
He, Jing, Zhang, Xia, Wei, Yunbo, Sun, Xiaolin, Chen, Yaping, Deng, Jun, Jin, Yuebo, Gan, Yuzhou, Hu, Xin, Jia, Rulin, Xu, Chuanhui, Hou, Zhaohua, Leong, Yew Ann, Zhu, Lei, Feng, Jinhong, An, Yuan, Jia, Yuan, Li, Chun, Liu, Xu, Ye, Hua, Ren, Limin, Li, Ru, Yao, Haihong, Li, Yuhui, Chen, Shi, Zhang, Xuewu, Su, Yin, Guo, Jianping, Shen, Nan ... Li, Zhanguo (2016). Low-dose interleukin-2 treatment selectively modulates CD4(+) T cell subsets in patients with systemic lupus erythematosus. Nature Medicine, 22 (9), 991-993. doi: 10.1038/nm.4148
Chevalier, Nina, Macia, Laurence, Tan, Jian K., Mason, Linda J., Robert, Remy, Thorburn, Alison N., Wong, Connie H. Y., Tsai, Louis M., Bourne, Katherine, Brink, Robert, Yu, Di and Mackay, Charles R. (2016). The role of follicular helper T cell molecules and environmental influences in autoantibody production and progression to inflammatory arthritis in mice. Arthritis and Rheumatology, 68 (4), 1026-1038. doi: 10.1002/art.39481
Ryg-Cornejo, Victoria, Ioannidis, Lisa Julia, Ly, Ann, Chiu, Chris Yu, Tellier, Julie, Hill, Danika Lea, Preston, Simon Peter, Pellegrini, Marc, Yu, Di, Nutt, Stephen Laurence, Kallies, Axel and Hansen, Diana Silvia (2016). Severe malaria infections impair germinal center responses by inhibiting T follicular helper cell differentiation. Cell Reports, 14 (1), 68-81. doi: 10.1016/j.celrep.2015.12.006
Vinuesa, Carola G., Linterman, Michelle A., Yu, Di and MacLennan, Ian C. M. (2016). Follicular helper T cells. Annual Review of Immunology, 34 (1), 335-368. doi: 10.1146/annurev-immunol-041015-055605
Chen, Yaping and Yu, Di (2015). TCF-1 at the Tfh and Th1 Divergence. Trends in Immunology, 36 (12), 758-760. doi: 10.1016/j.it.2015.11.001
Wang, Hao, Wei, Yunbo and Yu, Di (2015). Control of lymphocyte homeostasis and effector function by the aryl hydrocarbon receptor. International Immunopharmacology, 28 (2), 818-824. doi: 10.1016/j.intimp.2015.03.046
Kwok, Seung-Ki, Lee, Jennifer, Yu, Di, Kang, Kwi Young, Cho, Mi-La, Kim, Hae-Rim, Ju, Ji Hyeon, Lee, Sang-Heon, Park, Sung-Hwan and Kim, Ho-Youn (2015). A pathogenetic role for IL-21 in primary Sjogren syndrome. Nature Reviews Rheumatology, 11 (6), 368-374. doi: 10.1038/nrrheum.2014.225
Cheyalier, Nina, Thorburn, Alison N., Macia, Laurence, Tan, Jian, Juglair, Laurent, Yagita, Hideo, Yu, Di, Hansbro, Philip M. and Mackay, Charles R. (2014). Inflammation and lymphopenia trigger autoimmunity by suppression of IL-2-controlled regulatory T cell and increase of IL-21-mediated effector T cell expansion. Journal of Immunology, 193 (10), 4845-4858. doi: 10.4049/jimmunol.1302966
Yu, Di (2014). MicroRNAs in Tfh Cells: Micromanaging Inflammaging. Immunity, 41 (4), 509-+. doi: 10.1016/j.immuni.2014.10.003
Yu, Di, Chen, Yaping and Leong, Yew Ann (2014). Navigating double negatives: new pathways for regulating TFH differentiation. Nature Immunology, 15 (7), 597-599. doi: 10.1038/ni.2922
Palmer, Clovis S., Ostrowski, Matias, Gouillou, Maelenn, Tsai, Louis, Yu, Di, Zhou, Jingling, Henstridge, Darren C., Maisa, Anna, Hearps, Anna C., Lewin, Sharon R., Landay, Alan, Jaworowski, Anthony, McCune, Joseph M. and Crowe, Suzanne M. (2014). Increased glucose metabolic activity is associated with CD4+ R T-cell activation and depletion during chronic HIV infection. AIDS, 28 (3), 297-309. doi: 10.1097/QAD.0000000000000128
Tsai, Louis M. and Yu, Di (2014). Follicular helper T-cell memory: establishing new frontiers during antibody response. Immunology and Cell Biology, 92 (1), 57-63. doi: 10.1038/icb.2013.68
Yu, Di and Linterman, Michelle (2014). The temporospatial control of Tfh cells. Immunology and Cell Biology, 92 (1), 20-21. doi: 10.1038/icb.2013.86
He, Jing, Tsai, Louis M., Leong, Yew Ann, Hu, Xin, Ma, Cindy S., Chevalier, Nina, Sun, Xiaolin, Vandenberg, Kirsten, Rockman, Steve, Ding, Yan, Zhu, Lei, Wei, Wei, Wang, Changqi, Karnowski, Alexander, Belz, Gabrielle T., Ghali, Joanna R., Cook, Matthew C., Riminton, D. Sean, Veillette, Andre, Schwartzberg, Pamela L., Mackay, Fabienne, Brink, Robert, Tangye, Stuart G., Vinuesa, Carola G., Mackay, Charles R., Li, Zhanguo and Yu, Di (2013). Circulating precursor CCR7(lo)PD-1(hi) CXCR5(+) CD4(+) T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure. Immunity, 39 (4), 770-781. doi: 10.1016/j.immuni.2013.09.007
Chen, Zhian, Cui, Yanfang, Leong, Yew Ann, Beddoe, Travis and Yu, Di (2013). Efficient production of recombinant IL-21 proteins for pre-clinical studies by a two-step dilution refolding method. International Immunopharmacology, 16 (3), 376-381. doi: 10.1016/j.intimp.2013.02.017
He, Jing, Ding, Yan, Feng, Min, Guo, Jianping, Sun, Xiaolin, Zhao, Jing, Yu, Di and Li, Zhanguo (2013). Characteristics of Sjogren's syndrome in rheumatoid arthritis. Rheumatology, 52 (6), 1084-1089. doi: 10.1093/rheumatology/kes374
Pratama, Alvin, Ramiscal, Roybel R., Silva, Diego G., Das, Souvik K., Athanasopoulos, Vicki, Fitch, Jessica, Botelho, Natalia K., Chang, Pheh-Ping, Hu, Xin, Hogan, Jennifer J., Mana, Paula, Bernal, David, Korner, Heinrich, Yu, Di, Goodnow, Christopher C., Cook, Matthew C. and Vinuesa, Carola G. (2013). Roquin-2 shares functions with its paralog roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation. Immunity, 38 (4), 669-680. doi: 10.1016/j.immuni.2013.01.011
Lee, Sau K., Rigby, Robert J., Zotos, Dimitra, Tsai, Louis M., Kawamoto, Shimpei, Marshall, Jennifer L., Ramiscal, Roybel R., Chan, Tyani D., Gatto, Dominique, Brink, Robert, Yu, Di, Fagarasan, Sidonia, Tarlinton, David M., Cunningham, Adam F. and Vinuesa, Carola G. (2011). B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells. Journal of Experimental Medicine, 208 (7), 1377-1388. doi: 10.1084/jem.20102065
Cao, Qi, Wang, Changqi, Zheng, Dong, Wang, Ya, Lee, Vincent W. S., Wang, Yuan Min, Zheng, Guoping, Tan, Thian Kui, Yu, Di, Alexander, Stephen I., Harris, David C. H. and Wang, Yiping (2011). IL-25 induces M2 macrophages and reduces renal injury in proteinuric kidney disease. Journal of the American Society of Nephrology, 22 (7), 1229-1239. doi: 10.1681/ASN.2010070693
Chevalier, Nina, Jarrossay, David, Ho, Edwin, Avery, Danielle T., Ma, Cindy S., Yu, Di, Sallusto, Federica, Tangye, Stuart G. and Mackay, Charles R. (2011). CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses. Journal of Immunology, 186 (10), 5556-5568. doi: 10.4049/jimmunol.1002828
Yu, Di and Vinuesa, Carola G. (2010). The elusive identity of T follicular helper cells. Trends in Immunology, 31 (10), 377-383. doi: 10.1016/j.it.2010.07.001
Smith, Paul N., Freeman, Craig, Yu, Di, Chen, Mingming, Gatenby, Paul A., Parish, Christopher R. and Li, Rachel W. (2010). Heparanase in primary human osteoblasts. Journal of Orthopaedic Research, 28 (10), 1315-1322. doi: 10.1002/jor.21138
Yu, Di and Vinuesa, Carola G. (2010). Multiple checkpoints keep follicular helper T cells under control to prevent autoimmunity. Cellular and Molecular Immunology, 7 (3), 198-203. doi: 10.1038/cmi.2010.18
Athanasopoulos, Vicki, Barker, Andrew, Yu, Di, Tan, Andy H-M., Srivastava, Monika, Contreras, Nelida, Wang, Jianbin, Lam, Kong-Peng, Brown, Simon H. J., Goodnow, Christopher C., Dixon, Nicholas E., Leedman, Peter J., Saint, Robert and Vinuesa, Carola G. (2010). The ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs. Febs Journal, 277 (9), 2109-2127. doi: 10.1111/j.1742-4658.2010.07628.x
Linterman, Michelle A., Beaton, Laura, Yu, Di, Ramiscal, Roybel R., Srivastava, Monika, Hogan, Jennifer J., Verma, Naresh K., Smyth, Mark J., Rigby, Robert J. and Vinuesa, Carola G. (2010). IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses. Journal of Experimental Medicine, 207 (2), 353-363. doi: 10.1084/jem.20091738
Tsai, Louis M. and Yu, Di (2010). MicroRNAs in common diseases and potential therapeutic applications. Clinical and Experimental Pharmacology and Physiology, 37 (1), 102-107. doi: 10.1111/j.1440-1681.2009.05269.x
Luo, X., Tsai, L. M., Shen, N. and Yu, D. (2010). Evidence for microRNA-mediated regulation in rheumatic diseases. Annals of the Rheumatic Diseases, 69 (Suppl 1), 30-36. doi: 10.1136/ard.2009.117218
Yu, Di, Batten, Marcel, Mackay, Charles R. and King, Cecile (2009). Lineage specification and heterogeneity of T follicular helper cells. Current Opinion in Immunology, 21 (6), 619-625. doi: 10.1016/j.coi.2009.09.013
Maslowski, Kendle M., Vieira, Angelica T., Ng, Aylwin, Kranich, Jan, Sierro, Frederic, Yu, Di, Schilter, Heidi C., Rolph, Michael S., Mackay, Fabienne, Artis, David, Xavier, Ramnik J., Teixeira, Mauro M. and Mackay, Charles R. (2009). Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature, 461 (7268), 1282-1286. doi: 10.1038/nature08530
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Linterman, Michelle A., Rigby, Robert J., Wong, Raphael. K., Yu, Di, Brink, Robert, Cannons, Jennifer L., Schwartzberg, Pamela L., Cook, Matthew C., Walters, Giles D. and Vinuesa, Carola G. (2009). Follicular helper T cells are required for systemic autoimmunity. Journal of Experimental Medicine, 206 (3), 561-576. doi: 10.1084/jem.20081886
Vinuesa, Carola G., Rigby, Robert J. and Yu, Di (2009). Logic and extent of miRNA-mediated control of autoimmune gene expression. International Reviews of Immunology, 28 (3-4), 112-138. doi: 10.1080/08830180902934909
Wu, Zuopeng, Jia, Xinying, de la Cruz, Laura, Su, Xun-Cheng, Marzolf, Bruz, Troisch, Pamela, Zak, Daniel, Hamilton, Adam, Whittle, Belinda, Yu, Di, Sheahan, Daniel, Bertram, Edward, Aderem, Alan, Otting, Gottfried, Goodnow, Christopher C. and Hoyne, Gerard F. (2008). Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLL. Immunity, 29 (6), 863-875. doi: 10.1016/j.immuni.2008.11.004
Wei, Wei, Ma, Guang-Hui, Hu, Gang, Yu, Di, Mcleish, Tom, Su, Zhi-Guo and Shen, Zhe-Yu (2008). Preparation of hierarchical hollow CaCO3 particles and the application as anticancer drug carrier. Journal of the American Chemical Society, 130 (47), 15808-15810. doi: 10.1021/ja8039585
Vogelzang, Alexis, McGuire, Helen M., Yu, Di, Sprent, Jonathan, Mackay, Charles R. and King, Cecile (2008). A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity, 29 (1), 127-137. doi: 10.1016/j.immuni.2008.06.001
Li, Rachel W., Freeman, Craig, Yu, Di, Hindmarsh, Elizabeth J., Tymms, Kathleen E., Parish, Christopher R. and Smith, Paul N. (2008). Dramatic regulation of heparanase activity and angiogenesis gene expression in synovium from patients with rheumatoid arthritis. Arthritis and Rheumatism, 58 (6), 1590-1600. doi: 10.1002/art.23489
Yu, Di, Cook, Matthew C., Shin, Dong-Mi, Silva, Diego G., Marshall, Jennifer, Toellner, Kai-Michael, Havran, Wendy L., Caroni, Pico, Cooke, Michael P., Morse, Herbert C., MacLennan, Ian C. M., Goodnow, Christopher C. and Vinuesa, Carola G. (2008). Axon growth and guidance genes identify T-dependent germinal centre B cells. Immunology and Cell Biology, 86 (1), 3-14. doi: 10.1038/sj.icb.7100123
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