Mr James Monkman

O'Byrne, K., Shanmugasundaram, K.B., Ahmed, E., Kulasinghe, A., Monkman, J., Fletcher, J.A., Mainwaring, P.N., Masud, M.K., Park, H., Hossain, M.S.A., Yamauchi, Y., Sina, A.A.I., Wuethrich, A. and Trau, M. (2023). P1.23-04 Extracellular Small Vesicle Phosphorylated PD-L1 Liquid Biopsy Levels Correlate with Tumour Proportion Score (TPS) in NSCLC. Journal of Thoracic Oncology, 18 (11), S256. doi: 10.1016/j.jtho.2023.09.432

Kulasinghe, A., Monkman, J., Moradi, A., Yunis, J., Ivison, G., Mayer, A. and O'Byrne, K. (2023). MA09.03 High-Dimensional Profiling of the Tumour Microenvironment of Non-small Cell Lung Cancer. Journal of Thoracic Oncology, 18 (11), S129. doi: 10.1016/j.jtho.2023.09.173

Kulasinghe, A., Ma, N., Pratapa, A., Monkman, J., Braubach, O. and O'Byrne, K.J. (2023). 2323P Multi-omic spatial phenotyping of the NSCLC tumour microenvironment for the development of a spatial score associated with immunotherapy resistance. Annals of Oncology, 34, S1187. doi: 10.1016/j.annonc.2023.09.1352

Ladwa, R., Monkman, J., Sadeghirad, H., Cooper, C., Belz, G., Bowman, J., Schaider, H., Liu, H., Kulasinghe, A. and Porceddu, S. (2023). 1144P High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study. Annals of Oncology, 34, S685. doi: 10.1016/j.annonc.2023.09.2278

Monkman, James, Kim, Honesty, Mayer, Aaron, Mehdi, Ahmed, Matigian, Nicholas, Cumberbatch, Marie, Bhagat, Milan, Ladwa, Rahul, Mueller, Scott N., Adams, Mark N., O'Byrne, Ken and Kulasinghe, Arutha (2023). Multi‐omic and spatial dissection of immunotherapy response groups in non‐small cell lung cancer. Immunology, 169 (4), 487-502. doi: 10.1111/imm.13646

Ji, HaYeun, Jhaveri, Niyati, Pratapa, Aditya, Ma, Ning, Ben Cheikh, Bassem, Monkman, James, O’Byrne, Ken, Hughes, Brett, Kulasinghe, Arutha and Braubach, Oliver (2023). Spatial phenotyping of cytokine signatures reflecting the immunotherapy responses in head and neck cancer. The Journal of Immunology, 210 (1_Supplement), 171.09-171.09. doi: 10.4049/jimmunol.210.supp.171.09

Sadeghirad, Habib, Liu, Ning, Monkman, James, Ma, Ning, Cheikh, Bassem Ben, Jhaveri, Niyati, Tan, Chin Wee, Warkiani, Majid Ebrahimi, Adams, Mark N., Nguyen, Quan, Ladwa, Rahul, Braubach, Oliver, O’Byrne, Ken, Davis, Melissa, Hughes, Brett G. M. and Kulasinghe, Arutha (2023). Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy. Frontiers in Immunology, 14 1135489, 1-16. doi: 10.3389/fimmu.2023.1135489

Shojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438

Tran, M., Yoon, S., Teoh, M., Andersen, S., Lam, PY., Purdue, B. W., Raghubar, A., Hanson, S.J., Devitt, K., Jones, K., Walters, S., Monkman, J., Kulasinghe, A., Tuong, Z.K., Soyer, H.P., Frazer, I. H. and Nguyen, Q. (2022). A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages. Frontiers in Immunology, 13 911873, 911873. doi: 10.3389/fimmu.2022.911873

Sadeghirad, Habib, Monkman, James, Mehdi, Ahmed M., Ladwa, Rahul, O’Byrne, Ken, Hughes, Brett G. M. and Kulasinghe, Arutha (2022). Dissecting Tissue Compartment-Specific Protein Signatures in Primary and Metastatic Oropharyngeal Squamous Cell Carcinomas. Frontiers in Immunology, 13 895513, 1-11. doi: 10.3389/fimmu.2022.895513

Kulasinghe, Arutha, Monkman, James, Shah, Esha T., Matigian, Nicholas, Adams, Mark N. and O’Byrne, Ken (2022). Spatial profiling identifies prognostic features of response to adjuvant therapy in Triple Negative Breast Cancer (TNBC). Frontiers in Oncology, 11 798296, 798296. doi: 10.3389/fonc.2021.798296

Kulasinghe, Arutha, Tan, Chin Wee, dos Santos Miggiolaro, Anna Flavia Ribeiro, Monkman, James, SadeghiRad, Habib, Bhuva, Dharmesh D., da Silva Motta Junior, Jarbas, Vaz de Paula, Caroline Busatta, Nagashima, Seigo, Baena, Cristina Pellegrino, Souza-Fonseca-Guimaraes, Paulo, de Noronha, Lucia, McCulloch, Timothy, Rodrigues Rossi, Gustavo, Cooper, Caroline, Tang, Benjamin, Short, Kirsty R., Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Belz, Gabrielle T. and O'Byrne, Ken (2022). Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures. European Respiratory Journal, 59 (6) 2101881, 1-19. doi: 10.1183/13993003.01881-2021

Schimmel, Lilian, Chew, Keng Yih, Stocks, Claudia J., Yordanov, Teodor E., Essebier, Patricia, Kulasinghe, Arutha, Monkman, James, Santos Miggiolaro, Anna Flavia Ribeiro, Cooper, Caroline, Noronha, Lucia, Schroder, Kate, Lagendijk, Anne Karine, Labzin, Larisa I., Short, Kirsty R. and Gordon, Emma J. (2021). Endothelial cells are not productively infected by SARS‐CoV‐2. Clinical and Translational Immunology, 10 (10) e1350, e1350. doi: 10.1002/cti2.1350

Kulasinghe, Arutha, O'Leary, Connor, Monkman, James, Bharti, Vandhana, Irwin, Darryl, Dutta, Sanjay, Richard, Derek J., Hughes, Brett, Ladwa, Rahul and O'Byrne, Ken (2021). The identification of circulating tumour DNA using MassARRAY technology in non-small-cell lung cancer (NSCLC). Lung Cancer, 160, 73-77. doi: 10.1016/j.lungcan.2021.08.005

Sadeghi Rad, Habib, Monkman, James, Warkiani, Majid E., Ladwa, Rahul, O'Byrne, Ken, Rezaei, Nima and Kulasinghe, Arutha (2021). Understanding the tumor microenvironment for effective immunotherapy. Medicinal Research Reviews, 41 (3), 1474-1498. doi: 10.1002/med.21765

Monkman, James, Taheri, Touraj, Warkiani, Majid Ebrahimi, O’leary, Connor, Ladwa, Rahul, Richard, Derek, O’ Byrne, Ken and Kulasinghe, Arutha (2020). High-plex and high-throughput digital spatial profiling of non-small-cell lung cancer (NSCLC). Cancers, 12 (12) 3551, 1-16. doi: 10.3390/cancers12123551

Kulasinghe, Arutha, Monkman, James, Nalder, Mark, O’Leary, Connor, Ladwa, Rahul and O’Byrne, Ken (2020). Transformation or progression from adenocarcinoma to small cell lung cancer detected by serially tracking mutations in the blood. Reports, 3 (4) 33. doi: 10.3390/reports3040033

Herath, Sayuri, Razavi Bazaz, Sajad, Monkman, James, Ebrahimi Warkiani, Majid, Richard, Derek, O’Byrne, Ken and Kulasinghe, Arutha (2020). Circulating tumor cell clusters: insights into tumour dissemination and metastasis. Expert Review of Molecular Diagnostics, 20 (11), 1139-1147. doi: 10.1080/14737159.2020.1846523

Bhatia, Sugandha, Blick, Tony, Pinto, Cletus, Waltham, Mark, Monkman, James, Ivanova, Ekaterina, Pollock, Pamela M, Nagaraj, Shivashankar H., Wiegmans, Adrian P., Haviv, Izhak, Simpson, Kaylene J. and Thompson, Erik W. (2020). Identifying therapies to combat epithelial mesenchymal plasticity-associated chemoresistance to conventional breast cancer therapies using an shRNA library screen. Cancers, 12 (5) 1123, 1123. doi: 10.3390/cancers12051123

Sadeghi Rad, Habib, Bazaz, Sajad Razavi, Monkman, James, Ebrahimi Warkiani, Majid, Rezaei, Nima, O'Byrne, Ken and Kulasinghe, Arutha (2020). The evolving landscape of predictive biomarkers in immuno-oncology with a focus on spatial technologies. Clinical and Translational Immunology, 9 (11) e1215, 1-12. doi: 10.1002/cti2.1215

Crawley, James T. B., Zalli, Argita, Monkman, James H., Petri, Anastasis, Lane, David A., Ahnstrom, Josefin and Salles-Crawley, Isabelle I. (2019). Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant function. Journal of Thrombosis and Haemostasis, 17 (11), 1935-1949. doi: 10.1111/jth.14593

Bhatia, Sugandha, Monkman, James, Blick, Tony, Duijf, Pascal H.G., Nagaraj, Shivashankar H. and Thompson, Erik W. (2019). Multi-omics characterization of the spontaneous mesenchymal–epithelial transition in the PMC42 breast cancer cell lines. Journal of Clinical Medicine, 8 (8) 1253, 1253. doi: 10.3390/jcm8081253

Bhatia, Sugandha, Monkman, James, Blick, Tony, Pinto, Cletus, Waltham, Mark, Nagaraj, Shivashankar H. and Thompson, Erik W. (2019). Interrogation of phenotypic plasticity between epithelial and mesenchymal states in breast cancer. Journal of Clinical Medicine, 8 (6). doi: 10.3390/jcm8060893

Bhatia, Sugandha, Monkman, James, Toh, Alan Kie Leong, Nagaraj, Shivashankar H. and Thompson, Erik W. (2017). Targeting epithelial–mesenchymal plasticity in cancer: clinical and preclinical advances in therapy and monitoring. Biochemical Journal, 474 (19), 3269-3306. doi: 10.1042/bcj20160782

Sikulu, Maggy T., Monkman, James, Dave, Keyur A., Hastie, Marcus L., Dale, Patricia E., Kitching, Roger L., Killeen, Gerry F., Kay, Brian H., Gorman, Jeffry J. and Hugo, Leon E. (2015). Mass spectrometry identification of age-associated proteins from the malaria mosquitoes Anopheles gambiae s.s. and Anopheles stephensi. Data in Brief, 4, 461-467. doi: 10.1016/j.dib.2015.07.007

Sikulu, Maggy T., Monkman, James, Dave, Keyur A., Hastie, Marcus L., Dale, Patricia E., Kitching, Roger L., Killeen, Gerry F., Kay, Brian H., Gorman, Jeffery J. and Hugo, Leon E. (2015). Proteomic changes occurring in the malaria mosquitoes Anopheles gambiae and Anopheles stephensi during aging. Journal of Proteomics, 126, 234-244. doi: 10.1016/j.jprot.2015.06.008

Salles-Crawley, Isabelle I., Monkman, James H., Ahnstroem, Josefin, Lane, David A. and Crawley, James T. B. (2014). Vessel wall BAMBI contributes to hemostasis and thrombus stability. Blood, 123 (18), 2873-2881. doi: 10.1182/blood-2013-10-534024

Hugo, Leon E., Monkman, James, Dave, Keyur A., Wockner, Leesa F., Birrell, Geoff W., Norris, Emma L., Kienzle, Vivian J., Sikulu, Maggy T., Ryan, Peter A., Gorman, Jeffery J. and Kay, Brian H. (2013). Proteomic biomarkers for ageing the mosquito Aedes aegypti to determine risk of pathogen transmission. PLoS One, 8 (3) e58656, e58656.1-e58656.10. doi: 10.1371/journal.pone.0058656

Ma, Ning, Pratapa, Aditya, Monkman, James, O’Byrne, Ken and Kulasinghe, Arutha (2023). 105 Identifying a role for macrophages in predicting immunotherapy responses of non-small cell lung cancer (NSCLC). BMJ Publishing Group Ltd. doi: 10.1136/jitc-2023-sitc2023.0105

Jhaveri, Niyati, Klymyshyn, Dmytro, Pratapa, Aditya, Cheikh, Bassem Ben, Monkman, James, Prater, Michael, Nelson, Nadine, Mammadova, Najiba and Kulasinghe, Arutha (2023). 90 Spatio-temporal monitoring of the tumor microenvironment in cutaneous squamous cell carcinoma. BMJ Publishing Group Ltd. doi: 10.1136/jitc-2023-sitc2023.0090

Ma, Ning, Pratapa, Aditya, Monkman, James, O’Byrne, Ken, Braubach, Oliver and Kulasinghe, Arutha (2023). Abstract 6768: The potential predictive role of spatial phenotyping in non-small cell lung cancer. AACR Annual Meeting 2023, Orlando, FL United States, 14-19 April 2023. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2023-6768

Monkman, James, Moradi, Afshin, O'Leary, Connor, Wu, Zhenqin, Hamel, Steven, Mason, David, Schneider, Fabian, Mansfield, James Robert, Meyer, Aaron, O'Byrne, Ken and Kulasinghe, Arutha (2023). Abstract 4627: Immune profiling of immunotherapy and adjuvant chemotherapy pretreatment NSCLC tissues by CODEX. AACR Annual Meeting 2023, Orlando, FL United States, 14-19 April 2023. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2023-4627

Jhaveri, Niyati, Klymyshyn, Dmytro, Cheikh, Bassem B., Monkman, James, Winkowski, Dan, Mansfield, James, Basu, Subham, Prater, Michael, Nelson, Nadine, Belz, Gabrielle, Braubach, Oliver and Kulasinghe, Arutha (2023). Abstract 6774: The development of a spatial metabolic map of immunotherapy sensitive and resistant cutaneous skin carcinoma. AACR Annual Meeting 2023, Orlando, FL United States, 14-19 April 2023. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2023-6774

Sadeghirad, Habib, Liu, Ning, Monkman, James, Tan, Chin Wee, Cooper, Caroline, Caldera, Jeni, Church, Sarah, Schneider, Fabian, Mansfield, James Robert, O'Byrne, Ken, Davis, Melissa, Hughes, Brett and Kulasinghe, Arutha (2023). Abstract 4626: Spatial profiling of the tumor microenvironment in head and neck cancer identifies immune checkpoints and proteins involved in cell death signaling biomarkers of immunotherapy response. AACR Annual Meeting 2023, Orlando, FL United States, 14-19 April 2023. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2023-4626

Ji, HaYeun, Jhaveri, Niyati, Ma, Ning, Cheikh, Bassem B., Pratapa, Aditya, Monkman, James, O’Byrne, Ken, Hughes, Brett, Kulasinghe, Arutha and Braubach, Oliver (2023). Abstract 5647: Single cell, multiomic spatial phenotyping of immunotherapy responses in head and neck cancer. AACR Annual Meeting 2023, Orlando, FL United States, 14-19 April 2023. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2023-5647

Kulasinghe, Arutha, Tan, Chin Wee, Liu, Ning, Monkman, James, Killingbeck, Emily, Kim, Youngmi, Pan, Liuliu, Blick, Tony, Bhuva, Dharmesh, Feher, Kristen, Leon, Michael, Gregory, Mark, Short, Kirsty, Guimaraes, Fernando, Rhodes, Michael, Belz, Gabrielle and Davis, Melissa (2022). Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues. SITC 37th Annual Meeting (SITC 2022), Boston, MA USA, 8-12 November 2022. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/jitc-2022-sitc2022.0923

Ma, Ning, Pratapa, Aditya, Monkman, James, O’Byrne, Ken, Braubach, Oliver and Kulasinghe, Arutha (2022). Decoding immunotherapy responses with high-dimensional and high-throughput spatial phenotyping of non-small cell lung cancer (NSCLC). SITC 37th Annual Meeting (SITC 2022), Boston, MA USA, 8-12 November 2022. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/jitc-2022-sitc2022.0120

Kulasinghe, Arutha, Monkman, James, Kim, Honesty, Mayer, Aaron, Mehdi, Ahmed, Cumberbatch, Marie, Bhagat, Milan, Schneider, Fabian, Thaagard, Jeppe, Mansfield, James, Ladwa, Rahul, Mueller, Scott, Adams, Mark and O’byrne, Kenneth (2022). Delineation of spatial tissue signatures of immunotherapy response groups in non-small cell lung cancer (NSCLC). SITC 37th Annual Meeting (SITC 2022), Boston, MA USA, 8-12 November 2022. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/jitc-2022-sitc2022.0118

Kulasinghe, Arutha, Sadeghirad, Habib, Liu, Ning, Monkman, James, Tan, Chin Wee, Cooper, Caroline, Church, Sarah, Schneider, Fabian, Thaagard, Jeppe, Mansfield, James, O’byrne, Kenneth, Davis, Melissa and Hughes, Brett (2022). High-plex spatial proteomic profiling of immunotherapy response groups in head and neck cancer identifies tissue signatures associated with therapy response. SITC 37th Annual Meeting (SITC 2022), Boston, MA United States, 8–12 November 2022. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2022-sitc2022.0117

Monkman, James, Kim, Honesty, Mayer, Aaron, Mehdi, Ahmed, Matigian, Nicholas, Cumberbatch, Marie, Bhagat, Milan, Ladwa, Rahul, Mueller, Scott N., Adams, Mark N., O’Byrne, Ken and Kulasinghe, Arutha (2021). IL-2 stromal signatures dissect immunotherapy response groups in nonsmall cell lung cancer (NSCLC).

Mr James Monkman

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