Book Chapter
Hansford, Karl A., Ziora, Zyta M., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Solid-phase synthesis of octapeptin lipopeptides. Peptide synthesis: methods and protocols. (pp. 199-213) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-0227-0_13
Journal Articles
Ogunniyi, Abiodun D., Nguyen, Hang Thi, Hansford, Karl A., Cooper, Matthew A., Trott, Darren J. and Blaskovich, Mark A. T. (2023). Impact of the new membrane-targeting lipoglycopeptide antibiotic MCC5145 on the treatment of bacteremic pneumococcal pneumonia in mice. Microbiology Spectrum, 11 (5) e04459-22, 1-6. doi: 10.1128/spectrum.04459-22
Galochkin, Anton A., Baranov, Vladimir V., Hansford, Karl A., Friberg, Louise I. M., Strel'tzova, Elena D., Lipatov, Egor S., Nelyubina, Yulia V. and Kravchenko, Angelina N. (2023). Synthesis, structures and antifungal activity of selenoglycolurils. ChemistrySelect, 8 (14) e202300765, 1-11. doi: 10.1002/slct.202300765
Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238
Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381
Tran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-BolĂvar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166
Powell, Matthew, Blaskovich, Mark A. T. and Hansford, Karl A. (2021). Targeted protein degradation: the new frontier of antimicrobial discovery?. ACS Infectious Diseases, 7 (8) acsinfecdis.1c00203, 2050-2067. doi: 10.1021/acsinfecdis.1c00203
Frolov, Nikita A., Fedoseeva, Ksenia A., Hansford, Karl A. and Vereshchagin, Anatoly N. (2021). Novel phenyl-based bis-quaternary ammonium compounds as broad-spectrum biocides. ChemMedChem, 16 (19) cmdc.202100284, 2954-2959. doi: 10.1002/cmdc.202100284
Semenov, Victor V., Raihstat, Mikhail M., Konyushkin, Leonid D., Semenov, Roman V., Blaskovich, Mark A. T., Zuegg, Johannes, Elliott, Alysha G., Hansford, Karl A. and Cooper, Matthew A. (2021). Antimicrobial screening of a historical collection of over 140 000 small molecules. Mendeleev Communications, 31 (4), 484-487. doi: 10.1016/j.mencom.2021.07.015
Cho, Hye-Kyung, Karau, Melissa J., Greenwood-Quaintance, Kerryl E., Hansford, Karl A., Cooper, Matthew A., Blaskovich, Mark A. T. and Patel, Robin (2021). In Vitro activity of vancapticin MCC5145 against methicillin-resistant Staphylococcus aureus from periprosthetic joint infection. Antimicrobial Agents and Chemotherapy, 65 (5) e02443-20. doi: 10.1128/aac.02443-20
Vereshchagin, Anatoly N., Frolov, Nikita A., Konyuhova, Valeria Yu, Kapelistaya, Ekaterina A., Hansford, Karl A. and Egorov, Mikhail P. (2021). Investigations into the structure-activity relationship in gemini QACs based on biphenyl and oxydiphenyl linker. RSC Advances, 11 (6), 3429-3438. doi: 10.1039/d0ra08900a
Fuller, Amelia A., Dounay, Amy B., Schirch, Douglas, Rivera, Daniel G., Hansford, Karl A., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Blaskovich, Mark A. T., Hitchens, Jacob R., Burris-Hiday, Sarah, Tenorio, Kristiana, Mendez, Yanira, Samaritoni, J. Geno, O’Donnell, Martin J. and Scott, William L. (2020). Multi-institution research and education collaboration identifies new antimicrobial compounds. ACS Chemical Biology, 15 (12), 3187-3196. doi: 10.1021/acschembio.0c00732
De Oliveira, David M. P., Bohlmann, Lisa, Conroy, Trent, Jen, Freda E.-C., Everest-Dass, Arun, Hansford, Karl A., Bolisetti, Raghu, El-Deeb, Ibrahim M., Forde, Brian M., Phan, Minh-Duy, Lacey, Jake A., Tan, Aimee, Rivera-Hernandez, Tania, Brouwer, Stephan, Keller, Nadia, Kidd, Timothy J., Cork, Amanda J., Bauer, Michelle J., Cook, Gregory M., Davies, Mark R., Beatson, Scott A., Paterson, David L., McEwan, Alastair G., Li, Jian, Schembri, Mark A., Blaskovich, Mark A. T., Jennings, Michael P., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2020). Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translational Medicine, 12 (570) abb3791, eabb3791. doi: 10.1126/scitranslmed.abb3791
Vereshchagin, Anatoly N., Frolov, Nikita A., Konyuhova, Valeria Yu., Dorofeeva, Evgeniya O., Hansford, Karl A. and Egorov, Mikhail P. (2020). Synthesis and biological evaluation of novel bis-quaternary ammonium compounds with p-terphenyl spacer. Mendeleev Communications, 30 (4), 424-426. doi: 10.1016/j.mencom.2020.07.006
Zuegg, Johannes, Hansford, Karl A., Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). How to stimulate and facilitate early stage antibiotic discovery. ACS Infectious Diseases, 6 (6), 1302-1304. doi: 10.1021/acsinfecdis.0c00163
Zalevskaya, Olga, Gur’eva, Yana, Kutchin, Aleksandr and Hansford, Karl A. (2020). Antimicrobial and antifungal activities of terpene-derived palladium complexes. Antibiotics, 9 (5) 277, 277. doi: 10.3390/antibiotics9050277
Hansford, Karl A. (2020). Nontraditional antibiotics—challenges and triumphs. Antibiotics, 9 (4) 169, 169. doi: 10.3390/antibiotics9040169
Vereshchagin, Anatoly N., Frolov, Nikita A., Konyuhova, Valeria Yu., Hansford, Karl A. and Egorov, Mikhail P. (2019). Synthesis and microbiological properties of novel bis-quaternary ammonium compounds based on 4,4′-oxydiphenol spacer. Mendeleev Communications, 29 (5), 523-525. doi: 10.1016/j.mencom.2019.09.015
Gallardo-Godoy, Alejandra, Hansford, Karl, Muldoon, Craig, Becker, Bernd, Elliott, Alysha, Huang, Johnny, Pelingon, Ruby, Butler, Mark, Blaskovich, Mark and Cooper, Matthew (2019). Structure-function studies of polymyxin B lipononapeptides. Molecules, 24 (3) 553, 553. doi: 10.3390/molecules24030553
Vereshchagin, Anatoly N., Karpenko, Kirill A., Elinson, Michail N., Minaeva, Alexandra P., Goloveshkin, Alexander S., Hansford, Karl A. and Egorov, Mikhail P. (2019). One-pot five-component high diastereoselective synthesis of polysubstituted 2-piperidinones from aromatic aldehydes, nitriles, dialkyl malonates and ammonium acetate. Molecular Diversity, 24 (4), 1327-1342. doi: 10.1007/s11030-019-09997-6
Vereshchagin, Anatoly N., Gordeeva, Alexandra M., Frolov, Nikita A., Proshin, Pavel I., Hansford, Karl A. and Egorov, Mikhail P. (2019). Synthesis and microbiological properties of novel bis-quaternary ammonium compounds based on biphenyl spacer. European Journal of Organic Chemistry, 2019 (26), 4123-4127. doi: 10.1002/ejoc.201900319
Jarrad, Angie M., Blaskovich, Mark A. T., Prasetyoputri, Anggia, Karoli, Tomislav, Hansford, Karl A. and Cooper, Matthew A. (2018). Detection and investigation of Eagle effect resistance to vancomycin in Clostridium difficile with an ATP-bioluminescence assay. Frontiers in Microbiology, 9 (JUL) 1420, 1420. doi: 10.3389/fmicb.2018.01420
Blaskovich, Mark A. T., Hansford, Karl A., Butler, Mark S., Jia, ZhiGuang, Mark, Alan E. and Cooper, Matthew A. (2018). Developments in Glycopeptide Antibiotics. ACS Infectious Diseases, 4 (5), 715-735. doi: 10.1021/acsinfecdis.7b00258
Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w
Han, Mei-Ling, Shen, Hsin-Hui, Hansford, Karl A., Schneider, Elena K., Sivanesan, Sivashangarie, Roberts, Kade D., Thompson, Philip E., Le Brun, Anton P., Zhu, Yan, Sani, Marc-Antoine, Separovic, Frances, Blaskovich, Mark A. T., Baker, Mark A., Moskowitz, Samuel M., Cooper, Matthew A., Li, Jian and Velkov, Tony (2017). Investigating the interaction of octapeptin A3 with model bacterial membranes. ACS Infectious Diseases, 3 (8), 606-619. doi: 10.1021/acsinfecdis.7b00065
Becker, Bernd, Butler, Mark S., Hansford, Karl A., Gallardo-Godoy, Alejandra, Elliott, Alysha G., Huang, Johnny X., Edwards, David J., Blaskovich, Mark A. T. and Cooper, Matthew A. (2017). Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria. Bioorganic and Medicinal Chemistry Letters, 27 (11), 2407-2409. doi: 10.1016/j.bmcl.2017.04.027
Desselle, Mathilde R., Neale, Ruth, Hansford, Karl A., Zuegg, Johannes, Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2017). Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals. Future Science OA, 3 (2) FSO171, FSO171. doi: 10.4155/fsoa-2016-0093
Jarrad, A. M., Debnath, A., Miyamoto, Y., Hansford, K. A., Pelingon, R., Butler, M. S., Bains, T., Karoli, T., Blaskovich, M. A. T., Eckmann, L. and Cooper, M. A. (2016). Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis. European Journal of Medicinal Chemistry, 120, 353-362. doi: 10.1016/j.ejmech.2016.04.064
Hansford, Karl A., Blaskovich, Mark A. T. and Cooper, Matthew A. (2016). Chemical philanthropy: a path forward for antibiotic discovery?. Future Medicinal Chemistry, 8 (9), 925-929. doi: 10.4155/fmc-2016-0029
Bi, Sisi, Ranzoni, Andrea, Huang, Johnny X., Hansford, Karl and Cooper, Matthew A. (2015). Affinities and in-plane stress forces between glycopeptide antibiotics and biomimetic bacterial membranes. Sensing and Bio-Sensing Research, 3, 24-30. doi: 10.1016/j.sbsr.2014.10.003
Butler, Mark S., Hansford, Karl A., Blaskovich, Mark A. T., Halai, Reena and Cooper, Matthew A. (2014). Glycopeptide antibiotics: back to the future. Journal of Antibiotics, 67 (9), 631-644. doi: 10.1038/ja.2014.111
Cheng, Mu, Ziora, Zyta M., Hansford, Karl A., Blaskovich, Mark A., Butler, Mark S. and Cooper, Matthew A. (2014). Anti-cooperative ligand binding and dimerisation in the glycopeptide antibiotic dalbavancin. Organic and Biomolecular Chemistry, 12 (16), 2568-2575. doi: 10.1039/c3ob42428f
Tong, Wenyong, Gagnon, Martin, Sprules, Tara, Gilbert, Michael, Chowdhury, Shafinaz, Meerovitch, Karen, Hansford, Karl, Purisima, Enrico O., Blankenship, John W., Cheung, Nai-Kong V., Gehring, Kalle, Lubell, William D. and Saragovi, H. Uri (2010). Small-molecule ligands of GD2 ganglioside, designed from NMR studies, exhibit induced-fit binding and bioactivity. Chemistry and Biology, 17 (2), 183-194. doi: 10.1016/j.chembiol.2010.01.012
Hansford, Karl A., Guarin, Sergio Andres Perez, Skene, W. G. and Lubell, William D. (2006). Bis(pyrrol-2-yl)arylenes from the tandem bidirectional addition of vinyl grignard reagent to aryl diesters. Organic Chemistry, 37 (5), 7996-8000. doi: 10.1021/jo0510888
Hansford, Karl A., Zanzarova, Valeria, Dorr, Aurélie and Lubell, William D. (2004). Three-step solution-phase combinatorial access to 1,2-disubstituted and 1,2,5-trisubstituted pyrroles from carboxylic esters. Journal of Combinatorial Chemistry, 6 (6), 893-898. doi: 10.1021/cc049904x
Kaul, R, Brouillette, Y, Sajjadi, Z, Hansford, Karl and Lubell, W. D. (2004). Selective tert-butyl ester deprotection in the presence of acid labile protecting groups with use of ZnBr2. Journal of Organic Chemistry, 69 (18), 6131-6133. doi: 10.1021/jo0491206
Hansford, Karl A., Dettwiller, James E. and Lubell, William D. (2004). One-pot synthesis of homoallylic ketones from the addition of vinyl grignard reagent to carboxylic esters. ChemInform, 35 (16), 4887-4890. doi: 10.1021/ol0359822
Arumugam, Thiruma V., Arnold, Naomi, Proctor, Lavinia M., Newman, Michelle, Reid, Robert C., Hansford, Karl A., Fairlie, David P., Shiels, Ian A. and Taylor, Stephen M. (2003). Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. British Journal of Pharmacology, 140 (1), 71-80. doi: 10.1038/sj.bjp.0705402
Hansford, Karl A., Reid, Robert C., Clark, Chris I., Tyndall, Joel D. A., Whitehouse, Michael W., Guthrie, Tom, McGeary, Ross P., Schafer, Karl, Martin, Jennifer L. and Fairlie, David P. (2003). D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A(2) (IIa) with antiinflammatory activity. Chembiochem, 4 (2-3), 181-185. doi: 10.1002/cbic.200390029
Carman, Raymond M., Derbyshire, Roger P. C., Hansford, Karl A., Kadirvelraj, Renu and Robinson, Ward T. (2001). Towards the cis-bromination of double bonds. Australian Journal of Chemistry, 54 (2), 117-126. doi: 10.1071/CH01016
Carman, Raymond M., Hansford, Karl A. and Kennard, Colin H. L. (2000). Halogenated terpenoids. XXXI * Tribromides from the bromination of various exocyclic olefins. Australian Journal of Chemistry, 53 (5), 439-442.
Carman, R. M., Hansford, K. A. and Kennard, C. H. L. (2000). Halogenated terpenoids. XXXI tribromides from the bromination of various exocyclic olefins. Australian Journal of Chemistry, 53 (5), 439-442. doi: 10.1071/CH00041
Brecknell, Douglas J., Carman, Raymond M., Edwards, Ross A., Hansford, Karl, Karoli, Tomislav and Robinson, Ward T. (1997). Halogenated Terpenoids. XXIX The 1-Bromo 1-Bromomethyl Cyclohexyl System. Australian Journal of Chemistry, 50 (7), 689-700. doi: 10.1071/C96188
Patents
Gallardo-Goday, Alejandra, Cooper, Matthew, Blaskovich, Mark, Hansford, Karl and Elliott, Alysha (2019). Peptide antibiotics. WO2019084628.