Dr Natacha Omer
ATH - Senior Lecturer
Children's Health Queensland Clinical Unit
Researcher biography
Dr Natacha Omer is a paediatic oncologist at the Queensland Children's Hospital in Brisbane. She is specialised in solid tumours, with a spacial interest in paediatric and adolescent sarcomas, cancer immunotherapy and molecular oncology. She is undertaking a PhD in immunology studying natural killer (NK) cell immunotherapy in paediatric sarcomas at the Frazer Institute, University of Queensland, in Dr Fernando Guimaraes lab.
Journal Articles
Lau, Loretta M. S., Khuong-Quang, Dong-Anh, Mayoh, Chelsea, Wong, Marie, Barahona, Paulette, Ajuyah, Pamela, Senapati, Akanksha, Nagabushan, Sumanth, Sherstyuk, Alexandra, Altekoester, Ann-Kristin, Fuentes-Bolanos, Noemi A., Yeung, Veronica, Sullivan, Ashleigh, Omer, Natacha, Diamond, Yonatan, Jessop, Sophie, Battaglia, Lauren, Zhukova, Nataliya, Cui, Louise, Lin, Angela, Gifford, Andrew J., Fleuren, Emmy D. G., Dalla-Pozza, Luciano, Moore, Andrew S., Khaw, Seong-Lin, Eisenstat, David D., Gottardo, Nicholas G., Wood, Paul J., Tapp, Heather ... Ziegler, David S. (2024). Precision-guided treatment in high-risk pediatric cancers. Nature Medicine, 30 (7), 1913-1922. doi: 10.1038/s41591-024-03044-0
Wong, Joshua K. M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. EBioMedicine, 104 105176. doi: 10.1016/j.ebiom.2024.105176
Ramamurthy, Ashika, Connolly, Elizabeth A, Mar, Jasmine, Lewin, Jeremy, Bhadri, Vivek A, Phillips, Marianne B, Winstanley, Mark, Orme, Lisa M, Grimison, Peter, Connor, Joanna, Lazarakis, Smaro, Hong, Angela M, Omer, Natacha and Cayrol, Julie (2024). High-dose chemotherapy for Ewing sarcoma and Rhabdomyosarcoma: A systematic review by the Australia and New Zealand sarcoma association clinical practice guidelines working party. Cancer Treatment Reviews, 124 102694. doi: 10.1016/j.ctrv.2024.102694
Mayoh, Chelsea, Gifford, Andrew J., Terry, Rachael, Lau, Loretta M S, Wong, Marie, Rao, Padmashree, Shai-Hee, Tyler, Saletta, Federica, Khuong-Quang, Dong-Anh, Qin, Vicky, Mateos, Marion K., Meyran, Deborah, Miller, Katherine E., Yuksel, Aysen, Mould, Emily V A, Bowen-James, Rachel, Govender, Dinisha, Senapati, Akanksha, Zhukova, Nataliya, Omer, Natacha, Dholaria, Hetal, Alvaro, Frank, Tapp, Heather, Diamond, Yonatan, Pozza, Luciano Dalla, Moore, Andrew S., Nicholls, Wayne, Gottardo, Nicholas G., McCowage, Geoffrey ... Ekert, Paul G. (2023). A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer. Genome Medicine, 15 (1) 20, 20. doi: 10.1186/s13073-023-01170-x
Fleuren, Emmy D. G., Terry, Rachael L., Meyran, Deborah, Omer, Natacha, Trapani, Joseph A., Haber, Michelle, Neeson, Paul J. and Ekert, Paul G. (2021). Enhancing the potential of immunotherapy in paediatric sarcomas: breaking the immunosuppressive barrier with receptor tyrosine kinase inhibitors. Biomedicines, 9 (12) 1798, 1798. doi: 10.3390/biomedicines9121798
Omer, Natacha, Nicholls, Wayne, Ruegg, Bronte, Souza-Fonseca-Guimaraes, Fernando and Rossi, Gustavo Rodrigues (2021). Enhancing natural killer cell targeting of pediatric sarcoma. Frontiers in Immunology, 12 791206, 791206. doi: 10.3389/fimmu.2021.791206
Terry, Rachael L., Meyran, Deborah, Fleuren, Emmy D. G., Mayoh, Chelsea, Zhu, Joe, Omer, Natacha, Ziegler, David S., Haber, Michelle, Darcy, Phillip K., Trapani, Joseph A., Neeson, Paul J. and Ekert, Paul G. (2021). Chimeric antigen receptor T cell therapy and the immunosuppressive tumor microenvironment in pediatric sarcoma. Cancers, 13 (18) 4704, 4704. doi: 10.3390/cancers13184704
Omer, Natacha, Le Deley, Marie-Cecile, Piperno-Neumann, Sophie, Marec-Berard, Perrine, Italiano, Antoine, Corradini, Nadege, Bellera, Carine, Brugieres, Laurence and Gaspar, Nathalie (2017). Phase-II trials in osteosarcoma recurrences: a systematic review of past experience. European Journal of Cancer, 75, 98-108. doi: 10.1016/j.ejca.2017.01.005
Conference Papers
Koopman, Bevan, Wright, Tracey, Omer, Natacha, McCabe, Veronica and Zuccon, Guido (2021). Precision medicine search for paediatric oncology. 44th International ACM SIGIR Conference on Research and Development in Information Retrieval, Virtual, 11 - 15 July, 2021. New York, NY, United States: Association for Computing Machinery. doi: 10.1145/3404835.3462792
Khuong-Quang, Dong-Anh, Nagabushan, Sumanth, Manoharan, Neevika, Arndt, Greg, Barahona, Paulette, Cowley, Mark J, Ekert, Paul G, Failes, Tim, Bolanos, Noemi Fuentes, Gauthier, Maely, Gifford, Andrew J, Haber, Michelle, Kumar, Amit, Lock, Richard B, Marshall, Glenn M, Mayoh, Chelsea, Mould, Emily, Norris, Murray D, Gopalakrishnan, Anjana, Omer, Natacha, Trebilcock, Peter, Trahair, Toby N, Tsoli, Maria, Tucker, Katherine, Wong, Marie, Tyrrell, Vanessa, Lau, Loretta and S, Ziegler, David (2020). Precision medicine for paediatric high-grade diffuse midline gliomas - results from the zero childhood cancer comprehensive precision medicine program. 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), Karuizawa, Japan, 13-16 December 2020. Cary, NC, United States: Oxford University Press . doi: 10.1093/neuonc/noaa222.117