Emeritus Professor Michael Roberts
Emeritus Professor
Frazer Institute
Emeritus Professor Michael Roberts leads the Therapeutics Research Centre.
Researcher biography
Michael (Mike) Roberts is a NHMRC Senior Principal Research Fellow and Emeritus Professor of Clinical Pharmacology & Therapeutics and Director of the Therapeutics Research Centre in the Diamantina Institute at The University of Queensland, which is based in the Translational Research Institute adjacent to the Princess Alexandra Hospital in Brisbane, Qld, Australia. He is also Professor of Therapeutics & Pharmaceutical Science at the University of South Australia with laboratories in the Basil Hetzel Institute at The Queen Elizabeth Hospital in Adelaide, South Australia.
Publications
Books
Berner, Bret, Gordi, Toufigh, Benson, Heather A. E. and Roberts, Michael S. (2021). Drug delivery approaches: perspectives from pharmacokinetics and pharmacodynamics. Hoboken, NJ, United States: Wiley. doi: 10.1002/9781119772767
Roberts, Michael S. and Walters, Kenneth A. (2007). Dermal absorption and toxicity assessment: Second edition. CRC Press.
Chapman, John, Roberts, Michael and Stokes, Julie (2005). Final report on the evaluation of the Quality Care Pharmacy Program. Canberra A.C.T., Australia: Pharmacy Guild of Australia.
Book Chapters
Wang, Haolu, Yang, Haotian, Ruan, Qi, Roberts, Michael S. and Liang, Xiaowen (2022). Theranostic nanoparticles for imaging and targeted drug delivery to the liver. Fundamentals of drug delivery. (pp. 311-328) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119769644.ch12
Benson, Heather A.E. and Roberts, Michael S. (2022). Challenges and innovations of controlled drug delivery. Fundamentals of Drug Delivery. (pp. 3-14) edited by Heather A. E. Benson, Michael S. Roberts, Adrian C. Williams and Xiaowen Liang. Hoboken, NJ, United States: Wiley. doi: 10.1002/9781119769644.ch1
Holmes, Amy, Thorling, Camilla, Liu, Xin, Liang, Xiaowen, Wang, Haolu, Breunig, Hans G., König, Karsten, Studier, Hauke and Roberts, Michael S. (2018). Revealing interaction of dyes and nanomaterials by multiphoton imaging. Multiphoton microscopy and fluorescence lifetime imaging: applications in biology and medicine. (pp. 345-368) edited by Karsten König. Berlin, Germany: Walter de Gruyter. doi: 10.1515/9783110429985-020
Leite-Silva, V. R., Grice, Jeffrey E., Mohammed, Yousuf, Moghimi, Hamid R. and Roberts, Michael S. (2017). The influence of emollients on dermal and transdermal drug delivery. Percutaneous penetration enhancers drug penetration into/through the skin: methodology and general considerations. (pp. 77-93) edited by Nina Dragicevic and Howard I. Maibach. Berlin, Germany: Springer. doi: 10.1007/978-3-662-53270-6_5
Mohammed, Yousuf H., Moghimi, Hamid R., Yousef, Shereen A., Chandrasekaran, Navin C., Bibi, Césa R., Sukumar, Sinduja C., Grice, Jeffrey E., Sakran, Wedad and Roberts, Michael S. (2017). Efficacy, safety and targets in topical and transdermal active and excipient delivery. Percutaneous penetration enhancers drug penetration into/through the skin: methodology and general considerations. (pp. 369-391) edited by Nina Dragicevic and Howard I. Maibach. Berlin, Germany: Springer . doi: 10.1007/978-3-662-53270-6_23
Machado, A. C. H. R., Lopes, P. S., Raffier, C. P., Haridass, I. N., Roberts, M., Grice, J. and Leite-Silva, V. R. (2017). Skin penetration. Cosmetic Science and Technology: Theoretical Principles and Applications. (pp. 741-755) edited by KAZUTAMI SAKAMOTO, ROBERT Y. LOCHHEAD, HOWARD I. MAIBACH and YUJI YAMASHITA. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-802005-0.00046-X
Liang, Xiaowen, Wang, Haolu, Liu, Xin, Grice, Jeffrey, Xu, Zhi Ping and Roberts, Michael S. (2017). Related topic: Safety evaluation of nanomaterials. Skin permeation and disposition of therapeutic and cosmeceutical compounds. (pp. 313-322) edited by Kenji Sugibayashi. Tokyo, Japan: Springer Japan. doi: 10.1007/978-4-431-56526-0_28
Pastore, Michael N. and Roberts, Michael S. (2017). Selection of topically applied chemical candidates: transdermal drug delivery systems. Skin permeation and disposition of therapeutic and cosmeceutical compounds. (pp. 251-262) edited by Kenji Sugibayashi. Tokyo, Japan: Springer Japan. doi: 10.1007/978-4-431-56526-0_21
Grice, Jeffrey E., Moghimi, Hamid R., Ryan, Elizabeth, Zhang, Qian, Haridass, Isha, Mohammed, Yousuf and Roberts, Michael S. (2017). Non-formulation parameters that affect penetrant-skin-vehicle interactions and percutaneous absorption. Percutaneous penetration enhancers drug penetration into/through the skin: methodology and general considerations. (pp. 45-75) edited by Nina Dragicevic and Howard I. Maibach. Berlin, Germany: Springer . doi: 10.1007/978-3-662-53270-6_4
Liu, X., Wang, H., Liang, X. and Roberts, M. S. (2017). Hepatic metabolism in liver health and disease. Liver Pathophysiology: Therapies and Antioxidants. (pp. 391-400) edited by Pablo Muriel. Cambridge, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-804274-8.00030-8
Thorling, Camilla A., Holmes, Amy, Studier, Hauke, Liu, David, Liang, Xiaowen and Roberts, Michael S. (2016). Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. Multiphoton and fluorescence lifetime imaging microscopy in studying nanoparticle pharmacokinetics in skin and liver. (pp. 107-123) edited by Stefan G. Stanciu. Rijeka, Croatia: InTech. doi: 10.5772/63452
Benson, H. A. E., Mohammed, Y., Grice, J. E. and Roberts, M. S. (2016). Formulation effects on topical nanoparticle penetration. Nanoscience in dermatology. (pp. 115-126) edited by Michael R. Hamblin, Pinar Avci and Tarl W. Prow. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-802926-8.00009-4
Kuswahyuning, Rina, Grice, Jeffrey E., Moghimi, Hamid R. and Roberts, Michael S. (2015). Formulation effects in percutaneous absorption. Percutaneous penetration enhancers chemical methods in penetration enhancement : drug manipulation strategies and vehicle effects. (pp. 109-134) edited by Nina Dragicevic and Howard I. Maibach. Berlin / Heidelberg, Germany: Springer. doi: 10.1007/978-3-662-45013-0_9
Sanchez, Washington Y., Song, Zhen, Becker, Wolfgang, Koenig, Karsten and Roberts, Michael S. (2014). Fluorescence lifetime imaging for diagnostic and therapeutic intravital microscopy. Advances in intravital microscopy: from basic to clinical research. (pp. 371-418) edited by Roberto Weigert. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-017-9361-2_16
Anissimov, Yuri G. and Roberts, Michael S. (2014). Mathematical models for topical and transdermal drug products. Topical drug bioavailability, bioequivalence, and penetration. (pp. 249-298) edited by Vinod P. Shah, Howard I. Maibach and John Jenner. New York, NY, United States: Springer. doi: 10.1007/978-1-4939-1289-6_15
Grice, Jeffrey E., Prow, Tarl W., Kendall, Mark A. F. and Roberts, Michael S. (2012). Electrical and physical methods of skin penetration enhancement. Topical and transdermal drug delivery: Principles and practice. (pp. 43-65) edited by Heather A. E. Benson and Adam C. Watkinson. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781118140505.ch3
Wu, Ya-Ting, Anissimov, Yuri G. and Roberts, Michael S. (2011). Introduction to dermatokinetics. Dermatokinetics of therapeutic agents. (pp. 1-23) edited by S. Narasimha Murthy. Boca Raton, FL, United States: CRC Press.
Geusens, Barbara, Mollet, Ilse, Anderson, Chris D., Terras, Sarah, Roberts, Michael S. and Lambert, Jo (2011). Changes in skin immunity with age and disease. Innate immune system of skin and oral mucosa: properties and impact in pharmaceutics, cosmetics, and personal care products. (pp. 217-258) edited by Nava Dayan and Philip W. Wertz. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781118025338.ch11
Dancik, Yuri, Thompson, Camilla, Krishnan, Gayathri and Roberts, Michael S. (2010). Cutaneous metabolism and active transport in transdermal drug delivery. Toxicology of the skin. (pp. 69-82) edited by Nancy A. Monteiro-Riviere, A. Wallace Hayes, John A. Thomas and Donald E. Gardner. New York , NY, U.S.A.: Informa Healthcare USA.
Grice, Jeffrey E., Zhang, Qian and Roberts, Michael S. (2010). Chemical structure-skin transport relationships. Toxicology of the skin. (pp. 55-68) edited by Nancy A. Monteiro-Riviere. New York , NY, U.S.A.: Informa Healthcare USA. doi: 10.3109/9781420079180
Kruger, P., Liu, X. and Roberts, M. S. (2009). Optimizing drug dosing in the ICU. Optimizing Drug Dosing in the ICU. (pp. 859-869) edited by Vincent, JL. Berlin, Germany: Springer. doi: 10.1007/978-3-540-92276-6
Dancik, Yuri, Jepps, Owen G. and Roberts, Michael S. (2008). Beyond stratum corneum. Dermal absorption and toxicity assessment. (pp. 209-250) edited by Michael S. Roberts and Kenneth A. Walters. New York, USA: Informa Healthcare.
Bartholomaeus, Andrew, Rolls, Carolyn and Roberts, Michael S. (2008). Regulating modified-release drug delivery technologies in Australia. Modified-Release Drug Delivery Technology, Second Edition. (pp. 473-485) CRC Press.
Roberts, M.S. and Walters, K.A. (2008). Human Skin Morphology and Dermal Absorption. Dermal Absorption and Toxicity Assessment. (pp. 1-16) edited by Roberts, M.S. and Walters, K.A.. USA: Informa Healthcare.
Roberts, M.S., Bouwstra, J., Pirot, F. and Falson, F. (2008). Skin Hydration - A Key Determinant in Topical Absorption. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 115-128) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.
Roberts, M.S., Gierden, A., Riviere, Jim E and Monteiro-Riviere, Nancy. A (2008). Solvent and Vehicle Effects on the Skin. Dermal Absorption and Toxicity Assessment. (pp. 433-447) edited by Roberts, M.S. and Walters, K.A.. USA: Informa Healthcare.
Kanikkannan, N., Bonner, M., Singh, J. and Roberts, M.S. (2008). Iontophoresis. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 517-535) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.
Dancik, Y., Jepps, O. and Roberts, M. S. (2008). Physiologically based pharmacokinetics and pharmacodynamics of skin. Dermal Absorption and Toxicity Assessment. (pp. 179-207) edited by Michael S. Roberts and Kenneth A. Walters. USA: Informa Healthcare.
Roberts, Michael S., Bartholomaeus, Andrew, Wade, George, Ghani, Sultan and Marroum, Patrick J. (2008). Regulatory aspects in modified-release drug delivery. Modified-Release Drug Delivery Technology, Second Edition. (pp. 357-383) CRC Press.
Roberts, M.S. and Walters, K.A. (2008). Skin Structure, Pharmaceuticals, Cosmetics, and the Efficacy of Topically Applied Agents. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 1-10) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.
Whitehouse, M., Sarkar, M. and Roberts, M.S. (2008). Drugs for Pain and Inflammation. Dermatologic, Cosmeceutic, and Cosmetic Development -Therapeutic and Novel Approaches. (pp. 215-241) edited by Walters, K.A. and Roberts, M.S.. USA: Informa Healthcare.
Whitehouse, Michael W., Sarkar, Mantu and Roberts, Michael S. (2007). Drugs for pain and inflammation. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. (pp. 215-242) CRC Press.
Dancik, Yuri, Jepps, Owen G. and Roberts, Michael S. (2007). Physiologically based pharmacokinetics and pharmacodynamics of skin. Dermal Absorption and Toxicity Assessment, Second Edition. (pp. 179-208) CRC Press.
Roberts, Michael S., Bouwstra, Joke, Pirot, Fabrice and Falson, Françoise (2007). Skin hydration-a key determinant in topical absorption. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. (pp. 115-124) CRC Press.
Roberts, Michael S., Gierden, Audrey, Riviere, Jim E. and Monteiro-Riviere, Nancy A. (2007). Solvent and vehicle effects on the skin. Dermal Absorption and Toxicity Assessment, Second Edition. (pp. 433-448) CRC Press.
Kanikkannan, Narayanasamy, Bonner, Michael, Singh, Jagdish and Roberts, Michael S. (2007). Iontophoresis. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. (pp. 517-536) CRC Press.
Walters, Kenneth A. and Roberts, Michael S. (2007). Skin structure, pharmaceuticals, cosmetics, and the efficacy of topically applied agents. Dermatologic, Cosmeceutic, and Cosmetic Development: Therapeutic and Novel Approaches. (pp. 1-11) CRC Press.
Cross, Sheree and Roberts, Michael (2006). Dermal blood flow, lymphatics, and binding as determinants of topical absorption, clearance and distribution. Dermal Absorption Models in Toxicology and Pharmacology. (pp. 251-281) edited by Jim Edmond Riviere. Boca Raton Florida, USA: Taylor & Francis.
Cross, S.E., Anissimov, Y. and Roberts, M. S. (2005). The skin reservoir for topically applied solutes. Percutaneous Absorption. (pp. 213-234) edited by Robert L Bronaugh and Howard I Maibach. USA: Taylor & Francis Group.
Walters, K. and Roberts, M. S. (2005). Percutaneous absorption of sunscreens. Percutaneous Absorption. (pp. 681-700) edited by Robert L Bronaugh and Howard I Maibach. USA: Taylor & Francis Group.
Roberts, M. S. and Anissimov, Y. (2005). Mathematical models in peercutaneous absorption. Percutaneous Absorption. (pp. 1-44) edited by Robert L Bronaugh and Howard I Maibach. USA: Taylor & Francis Group.
Graham, G. G., Roberts, Michael S., Day, R. O. and Rainsford, K. D. (2004). Pharmacokinetics and metabolism of the salicylates. Aspirin and related drugs. (pp. 97-155) edited by K.D. Rainsford. London, U.K.: Taylor & Francis.
Walters, Kenneth A. and Roberts, Michael S. (2002). The structure and function of skin. Dermatological and Transdermal Formulations. (pp. 1-40) edited by Kenneth A. Walters. New York, United States: CRC Press.
Roberts, Michael S., Elizabeth Cross, Sheree and Pellett, Mark A. (2002). Skin transport. Dermatological and Transdermal Formulations. (pp. 89-196) edited by Kenneth A. Walters.. New York, United States: CRC Press.
Journal Articles
Mikkonen, Antti T., Martin, Jennifer, Upton, Richard N., Barker, Andrew O., Brumley, Carolyn M., Taylor, Mark P., Mackenzie, Lorraine and Roberts, Michael S. (2023). Spatio-temporal trends in livestock exposure to per- and polyfluoroalkyl substances (PFAS) inform risk assessment and management measures. Environmental Research, 225 115518, 1-14. doi: 10.1016/j.envres.2023.115518
Mangion, Sean E., Mackenzie, Lorraine, Roberts, Michael S. and Holmes, Amy M. (2023). Seborrheic dermatitis: topical therapeutics and formulation design. European Journal of Pharmaceutics and Biopharmaceutics, 185, 148-164. doi: 10.1016/j.ejpb.2023.01.023
Qiang, Shuping, Mohamed, Fahim, Mackenzie, Lorraine and Roberts, Michael S. (2023). Rapid determination of polyethoxylated tallow amine surfactants in human plasma by LC-MSMS. Talanta, 254 124115, 1-12. doi: 10.1016/j.talanta.2022.124115
Zhang, Qian, Alinaghi, Azadeh, Williams, Desmond B. and Roberts, Michael S. (2023). A thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: II. Maximum flux and solute diffusion through stratum corneum lipids. International Journal of Pharmaceutics, 631 122522, 1-11. doi: 10.1016/j.ijpharm.2022.122522
Alinaghi, Azadeh, Zhang, Qian, Williams, Desmond B., Mackenzie, Lorraine and Roberts, Michael S. (2023). Thermodynamic and kinetic analysis of human epidermal penetration of phenolic compounds: I. Stratum corneum solubility and partitioning. International Journal of Pharmaceutics, 630 122424, 1-10. doi: 10.1016/j.ijpharm.2022.122424
Zou, Da, Wu, Zeming, Yi, Xin, Hui, Yue, Yang, Guangze, Liu, Yun, Tengjisi,, Wang, Haofei, Brooks, Anastasia, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S., Gao, Huajian and Zhao, Chun-Xia (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences, 120 (1) e2214757120, e2214757120. doi: 10.1073/pnas.2214757120
Liu, Xin, Cheruvu, Hanumanth S., Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Ghosh, Priyanka, Grice, Jeffrey E. and Roberts, Michael S. (2022). Percutaneous absorption of steroids from finite doses: predicting urinary excretion from in vitro skin permeation testing. International Journal of Pharmaceutics, 625 122095, 1-16. doi: 10.1016/j.ijpharm.2022.122095
Arora, Sumit, Clarke, James, Tsakalozou, Eleftheria, Ghosh, Priyanka, Alam, Khondoker, Grice, Jeffery E., Roberts, Michael S., Jamei, Masoud and Polak, Sebastian (2022). Mechanistic modeling of in vitro skin permeation and extrapolation to in vivo for topically applied metronidazole drug products using a physiologically based pharmacokinetic model. Molecular Pharmaceutics, 19 (9), 3139-3152. doi: 10.1021/acs.molpharmaceut.2c00229
Amarah, A. A., Hadgraft, J., Roberts, M. S. and Anissimov, Y. G. (2022). Compartmental modeling of skin absorption and desorption kinetics: Donor solvent evaporation, variable diffusion/partition coefficients, and slow equilibration process within stratum corneum. International Journal of Pharmaceutics, 623 121902, 1-10. doi: 10.1016/j.ijpharm.2022.121902
Mohammed, Yousuf, Holmes, Amy, Kwok, Philip Chi Lip, Kumeria, Tushar, Namjoshi, Sarika, Imran, Mohammad, Matteucci, Lana, Ali, Masood, Tai, Waiting, Benson, Heather A.E. and Roberts, Michael S. (2022). Advances and future perspectives in epithelial drug delivery. Advanced Drug Delivery Reviews, 186 114293, 1-38. doi: 10.1016/j.addr.2022.114293
Cheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E and Roberts, Michael S. (2022). An updated database of human maximum skin fluxes and epidermal permeability coefficients for drugs, xenobiotics, and other solutes applied as aqueous solutions. Data in Brief, 42 108242, 1-9. doi: 10.1016/j.dib.2022.108242
Mangion, Sean E., Sandiford, Lydia, Mohammed, Yousuf, Roberts, Michael S. and Holmes, Amy M. (2022). Multi-modal imaging to assess the follicular delivery of zinc pyrithione. Pharmaceutics, 14 (5) 1076, 1-14. doi: 10.3390/pharmaceutics14051076
Al-Qurain, Aymen A., Upton, Richard N., Tadros, Rami, Roberts, Michael S. and Wiese, Michael D. (2022). Population pharmacokinetic model for tramadol and O-desmethyltramadol in older patients. European Journal of Drug Metabolism and Pharmacokinetics, 47 (3), 387-402. doi: 10.1007/s13318-022-00756-x
Rowland, Malcolm, Roberts, Michael S. and Pang, K Sandy (2022). In Defense of Current Concepts and Applications of Clearance in Drug Development and Therapeutics. Drug metabolism and disposition: the biological fate of chemicals, 50 (2), 187-190. doi: 10.1124/dmd.121.000637
Calcutt, Joshua J., Roberts, Michael S. and Anissimov, Yuri G. (2022). Predicting viable skin concentration: modelling the subpapillary plexus. Pharmaceutical Research, 39 (4), 783-793. doi: 10.1007/s11095-022-03215-z
Jung, Nathalie, Namjoshi, Sarika, Mohammed, Yousuf, Grice, Jeffrey E., Benson, Heather A. E., Raney, Sam G., Roberts, Michael S. and Windbergs, Maike (2022). Application of confocal raman microscopy for the characterization of topical semisolid formulations and their penetration into human skin ex vivo. Pharmaceutical Research, 39 (5), 935-948. doi: 10.1007/s11095-022-03245-7
Khabir, Zahra, Holmes, Amy M., Lai, Yi-Jen, Liang, Liuen, Deva, Anand, Polikarpov, Michael A., Roberts, Michael S. and Zvyagin, Andrei V. (2021). Human epidermal zinc concentrations after topical application of ZnO nanoparticles in sunscreens. International Journal of Molecular Sciences, 22 (22) 12372, 12372. doi: 10.3390/ijms222212372
Roberts, Michael S., Cheruvu, Hanumanth S., Mangion, Sean E., Alinaghi, Azadeh, Benson, Heather A.E., Mohammed, Yousuf, Holmes, Amy, van der Hoek, John, Pastore, Michael and Grice, Jeffrey E. (2021). Topical drug delivery: history, percutaneous absorption, and product development. Advanced Drug Delivery Reviews, 177 113929, 113929. doi: 10.1016/j.addr.2021.113929
Al-Qurain, Aymen A., Williams, Desmond B., Mackenzie, Lorraine, Roberts, Michael S. and Wiese, Michael D. (2021). Simultaneous LC-MS/MS quantification of oxycodone, tramadol and fentanyl and their metabolites (noroxycodone, oxymorphone, O- desmethyltramadol, N- desmethyltramadol, and norfentanyl) in human plasma and whole blood collected via venepuncture and volumetric absorptive micro sampling. Journal of Pharmaceutical and Biomedical Analysis, 203 114171, 1-8. doi: 10.1016/j.jpba.2021.114171
Mangion, Sean E., Holmes, Amy M. and Roberts, Michael S. (2021). Targeted delivery of zinc pyrithione to skin epithelia. International Journal of Molecular Sciences, 22 (18) 9730. doi: 10.3390/ijms22189730
Dabbaghi, Maryam, Namjoshi, Sarika, Panchal, Bhavesh, Grice, Jeffrey E., Prakash, Sangeeta, Roberts, Michael Stephen and Mohammed, Yousuf (2021). Viscoelastic and deformation characteristics of structurally different commercial topical systems. Pharmaceutics, 13 (9) 1351. doi: 10.3390/pharmaceutics13091351
Brooks, Anastasia, Liang, Xiaowen, Zhang, Yonglong, Zhao, Chun-Xia, Roberts, Michael S., Wang, Haolu, Zhang, Lei and Crawford, Darrell H.G. (2021). Liver organoid as a 3D in vitro model for drug validation and toxicity assessment. Pharmacological Research, 169 105608, 105608. doi: 10.1016/j.phrs.2021.105608
Zou, Da, Wang, Haolu, Liu, Xin, Xu, Zhi Ping, Roberts, Michael S. and Zhao, Chun-Xia (2021). Artificial cells for the treatment of liver diseases. Acta Biomaterialia, 130, 98-114. doi: 10.1016/j.actbio.2021.06.012
Liu, Xin, Anissimov, Yuri G., Grice, Jeffrey E., Cheruvu, Hanumanth Srikanth, Ghosh, Priyanka, Raney, Sam G., Maibach, Howard and Roberts, Michael S. (2021). Relating transdermal delivery plasma pharmacokinetics with in vitro permeation test (IVPT) findings using diffusion and compartment-in-series models. Journal of Controlled Release, 334, 37-51. doi: 10.1016/j.jconrel.2021.04.010
Gebremichael, Lemlem G., Suppiah, Vijayaprakash, Wiese, Michael D., Mackenzie, Lorraine, Phillips, Craig, Williams, Desmond B. and Roberts, Michael S. (2021). Efficacy and safety of statins in ethnic differences: A lesson for application in Indigenous Australian patient care. Pharmacogenomics, 22 (9), 553-571. doi: 10.2217/pgs-2020-0152
Buckley, Nicholas A., Fahim, Mohamed, Raubenheimer, Jacques, Gawarammana, Indika B., Eddleston, Michael, Roberts, Michael S. and Dawson, Andrew H. (2021). Case fatality of agricultural pesticides after self-poisoning in Sri Lanka: a prospective cohort study. The Lancet Global Health, 9 (6), e854-e862. doi: 10.1016/S2214-109X(21)00086-3
Rambabu, Lekaashree, Mohamed, Fahim, Dhanarisi, Jeevan, Gawarammana, Indika, Raubenheimer, Jacques, Mackenzie, Lorraine, Roberts, Michael S., Buckley, Nicholas and Eddleston, Michael (2021). Acute phenthoate self-poisoning: a prospective case series. Clinical Toxicology, 60 (2), 1-7. doi: 10.1080/15563650.2021.1917596
Al-Qurain, Aymen A., Upton, Richard, Williams, Desmond B., Mackenzie, Lorraine, Phillips, Craig, Russell, Patrick T., Tadros, Rami, Roberts, Michael S. and Wiese, Michael D. (2021). Population pharmacokinetic model of subcutaneous fentanyl in older acute care patients. European Journal of Clinical Pharmacology, 77 (9), 1357-1368. doi: 10.1007/s00228-021-03126-9
Al-Qurain, Aymen Ali, Gebremichael, Lemlem G., Khan, Mohammed S., Williams, Desmond B., Mackenzie, Lorraine, Phillips, Craig, Russell, Patrick, Roberts, Michael S. and Wiese, Michael D. (2021). Opioid prescribing and risk of drug-opioid interactions in older discharged patients with polypharmacy in Australia. International Journal of Clinical Pharmacy, 43 (2), 365-374. doi: 10.1007/s11096-020-01191-1
Abd, Eman, Gomes, Juliana, Sales, Caroline Cianga, Yousef, Shereen, Forouz, Farzaneh, Telaprolu, Krishna Chaitanya, Roberts, Michael S., Grice, Jeffrey E., Lopes, Patricia Santos, Leite‐Silva, Vânia R. and Newton, Andréo‐Filho (2021). Deformable liposomes as enhancer of caffeine penetration through human skin in a Franz diffusion cell test. International Journal of Cosmetic Science, 43 (1) ics.12659, 1-10. doi: 10.1111/ics.12659
Hosseini, Maryam, Roberts, Michael S., Aboofazeli, Reza and Moghimi, Hamid R. (2021). Measurement of Hansen Solubility Parameters of third-degree burn eschar. Burns, 48 (4), 860-871. doi: 10.1016/j.burns.2021.07.017
Calcutt, Joshua J., Roberts, Michael S. and Anissimov, Yuri G. (2021). Modeling drug transport within the viable skin - a review. Expert Opinion on Drug Metabolism and Toxicology, 17 (1), 105-119. doi: 10.1080/17425255.2020.1832081
Barkauskas, Deborah S., Medley, Gregory, Liang, Xiaowen, Mohammed, Yousuf H., Thorling, Camilla A., Wang, Haolu and Roberts, Michael S. (2020). Using in vivo multiphoton fluorescence lifetime imaging to unravel disease-specific changes in the liver redox state. Methods and Applications in Fluorescence, 8 (3) 034003, 034003. doi: 10.1088/2050-6120/ab93de
Holmes, Amy M., Kempson, Ivan, Turnbull, Tyron, Paterson, David and Roberts, Michael S. (2020). Penetration of Zinc into Human Skin after Topical Application of Nano Zinc Oxide Used in Commercial Sunscreen Formulations. ACS Applied Bio Materials, 3 (6), 3640-3647. doi: 10.1021/acsabm.0c00280
Ezati, Negin, Roberts, Michael Stephen, Zhang, Qian and Moghimi, Hamid Reza (2020). Measurement of hansen solubility parameters of human stratum corneum. Iranian Journal of Pharmaceutical Research, 19 (3), 572-578. doi: 10.22037/ijpr.2019.112435.13755
Liu, Xin, Yousef, Shereen, Anissimov, Yuri G., van der Hoek, John, Tsakalozou, Eleftheria, Ni, Zhanglin, Grice, Jeffrey E. and Roberts, Michael S. (2020). Diffusion modelling of percutaneous absorption kinetics. Predicting urinary excretion from in vitro skin permeation tests (IVPT) for an infinite dose. European Journal of Pharmaceutics and Biopharmaceutics, 149, 30-44. doi: 10.1016/j.ejpb.2020.01.018
Namjoshi, Sarika, Dabbaghi, Maryam, Roberts, Michael S., Grice, Jeffrey E. and Mohammed, Yousuf (2020). Quality by design: development of the quality target product profile (QTPP) for semisolid topical products. Pharmaceutics, 12 (3) 287, 287. doi: 10.3390/pharmaceutics12030287
Al-Qurain, Aymen Ali, Gebremichael, Lemlem G., Khan, Muhammad Suleman, Williams, Desmond B., Mackenzie, Lorraine, Phillips, Craig, Russell, Patrick, Roberts, Michael S. and Wiese, Michael D. (2020). Prevalence and factors associated with analgesic prescribing in poly-medicated elderly patients. Drugs and Aging, 37 (4), 291-300. doi: 10.1007/s40266-019-00742-0
Ruan, Qi, Wang, Haolu, Burke, Leslie J., Bridle, Kim R., Li, Xinxing, Zhao, Chun-Xia, Crawford, Darrell H. G., Roberts, Michael S. and Liang, Xiaowen (2020). Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma. International Journal of Cancer, 147 (6) ijc.32899, 1519-1527. doi: 10.1002/ijc.32899
Nastiti, Christofori M. R. R., Ponto, Thellie, Mohammed, Yousuf, Roberts, Michael S. and Benson, Heather A. E. (2020). Novel nanocarriers for targeted topical skin delivery of the antioxidant resveratrol. Pharmaceutics, 12 (2) 108, 108. doi: 10.3390/pharmaceutics12020108
Holmes, Amy M., Mackenzie, Lorraine and Roberts, Michael S. (2020). Disposition and measured toxicity of zinc oxide nanoparticles and zinc ions against keratinocytes in cell culture and viable human epidermis. Nanotoxicology, 14 (2), 263-274. doi: 10.1080/17435390.2019.1692382
Mohammed, Yousuf, Barkauskas, Deborah, Holmes, Amy, Grice, Jeffrey and Roberts, Michael (2020). Noninvasive in vivo human multiphoton microscopy: a key method in proving nanoparticulate zinc oxide sunscreen safety. Journal of Biomedical Optics, 25 (1) 014509, 014509-014509. doi: 10.1117/1.JBO.25.1.014509
Wang, Haolu, Burke, Leslie J., Patel, Jatin, Tse, Brian W.C., Bridle, Kim R., Cogger, Victoria C., Li, Xinxing, Liu, Xin, Yang, Haotian, Crawford, Darrell H. G., Roberts, Michael S., Gao, Wenchao and Liang, Xiaowen (2020). Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury. Theranostics, 10 (15), 6715-6727. doi: 10.7150/thno.44900
Mohammed, Yousuf H., Haridass, Isha N., Grice, Jeffrey E., Benson, Heather A.E. and Roberts, Michael S. (2020). Bathing does not facilitate human skin penetration or adverse cellular effects of nanoparticulate zinc oxide sunscreens after topical application. Journal of Investigative Dermatology, 140 (8), 1656-1659. doi: 10.1016/j.jid.2019.12.024
Cheruvu, Hanumanth Srikanth, Liu, Xin, Grice, Jeffrey E. and Roberts, Michael S. (2020). Modeling percutaneous absorption for successful drug discovery and development. Expert Opinion on Drug Discovery, 15 (10), 1-18. doi: 10.1080/17460441.2020.1781085
Isoardi, K. Z., Page, C. B., Roberts, M. S. and Isbister, G. K. (2020). Life-threatening triclopyr poisoning due to diethylene glycol monoethyl ether solvent. Clinical Toxicology, 59 (1), 1-4. doi: 10.1080/15563650.2020.1757103
Yousef, Shereen A., Mohammed, Yousuf H., Namjoshi, Sarika, Grice, Jeffrey E., Benson, Heather A. E., Sakran, Wedad and Roberts, Michael S. (2019). Mechanistic evaluation of enhanced curcumin delivery through human skin in vitro from optimised nanoemulsion formulations fabricated with different penetration enhancers. Pharmaceutics, 11 (12) 639, 639. doi: 10.3390/pharmaceutics11120639
Latter, Gemma, Grice, Jeffrey E., Mohammed, Yousuf, Roberts, Michael S. and Benson, Heather A. E. (2019). Targeted topical delivery of retinoids in the management of acne vulgaris: Current formulations and novel delivery systems. Pharmaceutics, 11 (10) 490, 490. doi: 10.3390/pharmaceutics11100490
Haridass, Isha N., Wei, Jonathan C. J., Mohammed, Yousuf H., Crichton, Michael L., Anderson, Christopher D., Henricson, Joakim, Sanchez, Washington Y., Meliga, Stefano C., Grice, Jeffrey E., Benson, Heather A. E., Kendall, Mark A. F. and Roberts, Michael S. (2019). Cellular metabolism and pore lifetime of human skin following microprojection array mediation. Journal of Controlled Release, 306, 59-68. doi: 10.1016/j.jconrel.2019.05.024
Rainsford, K. D., Roberts, Michael S., Nencioni, Alessandro and Jones, Clarence (2019). Rationale and evidence for the incorporation of heparin into the diclofenac epolamine medicated plaster. Current Medical Research and Opinion, 35 (6), 989-1002. doi: 10.1080/03007995.2018.1551194
Nastiti, Christofori M.R.R., Mohammed, Yousuf, Telaprolu, Krishna C., Liang, Xiaowen, Grice, Jeffrey E., Roberts, Michael S. and Benson, Heather A.E. (2019). Evaluation of quantum dot skin penetration in porcine skin: effect of age and anatomical site of topical application. Skin Pharmacology and Physiology, 32 (4), 1-10. doi: 10.1159/000499435
Abd, Eman, Benson, Heather A.E., Mohammed, Yousuf H., Roberts, Michael S. and Grice, Jeffrey E. (2019). Permeation mechanism of caffeine and naproxen through in vitro human epidermis: Effect of vehicles and penetration enhancers. Skin Pharmacology and Physiology, 32 (3), 132-141. doi: 10.1159/000497225
Sandiford, Lydia , Holmes, Amy M. , Mangion, Sean E. , Mohammed, Yousuf H. , Zvyagin, Andrei V. and Roberts, Michael S. (2019). Optical characterisation of zinc pyrithione. Photochemistry and Photobiology, 95 (5) php.13100, 1142-1150. doi: 10.1111/php.13100
Schultz, Hayley B., Vasani, Roshan B., Holmes, Amy M., Roberts, Michael S. and Voelcker, Nicolas H. (2019). Stimulus-responsive antibiotic releasing systems for the treatment of wound infections. ACS Applied Bio Materials, 2 (2), 704-716. doi: 10.1021/acsabm.8b00577
Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021
Mohammed, Yousuf H., Holmes, Amy, Haridass, Isha N., Sanchez, Washington Y., Studier, Hauke, Grice, Jeffrey E., Benson, Heather A. E. and Roberts, Michael S. (2019). Support for the safe use of zinc oxide nanoparticle sunscreens: lack of skin penetration or cellular toxicity after repeated application in volunteers. Journal of Investigative Dermatology, 139 (2), 308-315. doi: 10.1016/j.jid.2018.08.024
Benson, Heather A. E., Grice, Jeffrey E., Mohammed, Yousuf, Namjoshi, Sarika and Roberts, Michael S. (2019). Topical and transdermal drug delivery: from simple potions to smart technologies. Current Drug Delivery, 16 (5), 444-460. doi: 10.2174/1567201816666190201143457
Wang, Haolu, Lu, Hao, Yang, Haotian, Zhang, Xianwen, Thompson, Erik W., Roberts, Michael S., Hu, Zhigian, Liang, Xiaowen and Li, Xinxing (2019). Impact of age on risk of lymph node positivity in patients with colon cancer. Journal of Cancer, 10 (9), 2102-2108. doi: 10.7150/jca.28377
Xiao, Wenjin, Green, Thomas I. P., Liang, Xiaowen, Delint, Rosalia Cuahtecontzi, Perry, Guillaume, Roberts, Michael S., Le Vay, Kristian, Back, Catherine R., Ascione, Raimomdo, Wang, Haolu, Race, Paul R. and Perriman, Adam W. (2019). Designer artificial membrane binding proteins to direct stem cells to the myocardium. Chemical Science, 10 (32), 7610-7618. doi: 10.1039/c9sc02650a
Vieira, Camila O., Grice, Jeffrey E., Roberts, Michael S., Haridass, Isha N., Duque, Marcelo Dutra, Lopes, Patrícia S., Leite-Silva, Vânia R. and Martins, Tereza S. (2019). ZnO:SBA-15 Nanocomposites for potential use in sunscreen: Preparation, properties, human skin penetration and toxicity. Skin Pharmacology and Physiology, 32 (1), 32-42. doi: 10.1159/000491758
Wei, Jonathan C. J., Haridass, Isha N., Crichton, Michael L., Mohammed, Yousuf H., Meliga, Stefano C., Sanchez, Washington Y., Grice, Jeffrey E., Benson, Heather A. E., Roberts, Michael S. and Kendall, Mark A. F. (2018). Space- and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arrays. Scientific Reports, 8 (1) 17759, 1-15. doi: 10.1038/s41598-018-36009-8
Wang, Haolu, Yang, Haotian, Xu, Zhi Ping, Liu, Xin, Roberts, Michael S. and Liang, Xiaowen (2018). Anionic long-circulating quantum dots for long-term intravital vascular imaging. Pharmaceutics, 10 (4) 244, 244. doi: 10.3390/pharmaceutics10040244
Le, Tyson, Gong, Yuewen, Wang, Guqi, Davies, Neal M., Lillico, Ryan, Lakowski, Ted, Roberts, Michael S. and Burczynski, Frank J (2018). The antioxidant activity of recombinant rat hepatic fatty acid binding protein t94a variant. Journal of Pharmacy and Pharmaceutical Sciences, 21 (1S), 309s-324s. doi: 10.18433/jpps30246
Yang, Haotian, Villani, Rehan M., Wang, Haolu, Simpson, Matthew J., Roberts, Michael S., Tang, Min and Liang, Xiaowen (2018). The role of cellular reactive oxygen species in cancer chemotherapy. Journal of Experimental and Clinical Cancer Research, 37 (1) 266, 266. doi: 10.1186/s13046-018-0909-x
Yamada, Miko, Tayeb, Hossam, Wang, Hequn, Dang, Nhung, Mohammed, Yousuf H., Osseiran, Sam, Belt, Paul J., Roberts, Michael S., Evans, Conor L., Sainsbury, Frank and Prow, Tarl W. (2018). Using elongated microparticles to enhance tailorable nanoemulsion delivery in excised human skin and volunteers. Journal of Controlled Release, 288, 264-276. doi: 10.1016/j.jconrel.2018.09.012
Alahakoon, Chanika, Dassanayake, Tharaka L., Gawarammana, Indika B., Sedgwick, E. Michael, Weerasinghe, Vajira S., Abdalla, Ahmed, Roberts, Michael S. and Buckley, Nicholas A. (2018). Prediction of organophosphorus insecticide-induced intermediate syndrome with stimulated concentric needle single fibre electromyography. PLoS ONE, 13 (9) e0203596, e0203596. doi: 10.1371/journal.pone.0203596
Amarah, A. A., Petlin, D. G., Grice, J. E., Hadgraft, J., Roberts, M. S. and Anissimov, Y. G. (2018). Compartmental modeling of skin transport. European Journal of Pharmaceutics and Biopharmaceutics, 130, 336-344. doi: 10.1016/j.ejpb.2018.07.015
Abd, Eman, Benson, Heather A. E., Roberts, Michael S. and Grice, Jeffrey E. (2018). Follicular penetration of caffeine from topically applied nanoemulsion formulations containing penetration enhancers: in vitro human skin studies. Skin Pharmacology and Physiology, 31 (5), 252-260. doi: 10.1159/000489857
Warren, Sean C., Nobis, Max, Magenau, Astrid, Mohammed, Yousuf H., Herrmann, David, Moran, Imogen, Vennin, Claire, Conway, James R. W., Mélénec, Pauline, Cox, Thomas R., Wang, Yingxiao, Morton, Jennifer P., Welch, Heidi C. E., Strathdee, Douglas, Anderson, Kurt I., Phan, Tri Giang, Roberts, Michael S. and Timpson, Paul (2018). Removing physiological motion from intravital and clinical functional imaging data. eLife, 7 e35800. doi: 10.7554/eLife.35800
Morley, Kirsten C., Baillie, Andrew, Fraser, Isabel, Furneaux-Bate, Ainsley, Dore, Glenys, Roberts, Michael, Abdalla, Ahmed, Nghi Phung, and Haber, Paul S. (2018). Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial. British Journal of Psychiatry, 212 (6), 362-369. doi: 10.1192/bjp.2018.13
Garcia, Maria Teresa Junqueira, Vasconcelos, Fabia Leal Lopes, Raffier, Chloe Patricia, Roberts, Michael Stephen, Grice, Jeffrey Ernest, Benson, Heather Ann Elizabeth and Leite-Silva, Vania Rodrigues (2018). Alternative methods to animal studies for the evaluation of topical/transdermal drug delivery systems. Current Topics in Medicinal Chemistry, 18 (4), 287-299. doi: 10.2174/1568026618666180412153214
Holmes, Amy M., Kempson, Ivan, Turnbull, Tyron, Paterson, David and Roberts, Michael S. (2018). Imaging the penetration and distribution of zinc and zinc species after topical application of zinc pyrithione to human skin. Toxicology and Applied Pharmacology, 343, 40-47. doi: 10.1016/j.taap.2018.02.012
Chiew, Angela L., Wright, Daniel F. B., Dobos, Nicola M., McArdle, Kylie, Mostafa, Ahmed A., Newth, Annemarie, Roberts, Michael S. and Isbister, Geoffrey K. (2018). "Massive" metformin overdose. British Journal of Clinical Pharmacology, 84 (12), 2923-2927. doi: 10.1111/bcp.13582
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2018). Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. The Journal of Antimicrobial Chemotherapy, 73 (6), 1647-1650. doi: 10.1093/jac/dky057
Rzhevskiy, Alexey S., Telaprolu, Krishna, Mohammed, Yousuf H., Grice, Jeffrey E., Roberts, Michael S. and Anissimov, Yuri G. (2018). Using a simple equation to predict the microporation-enhanced transdermal drug flux. European Journal of Pharmaceutics and Biopharmaceutics, 127, 12-18. doi: 10.1016/j.ejpb.2018.01.019
Chan, Betty S. H., Chiew, Angela L., Grainger, Sarah, Page, Colin B., Gault, Alan, Mostafa, Ahmed, Roberts, Michael S., Buckley, Nicholas A. and Isbister, Geoffrey K. (2018). Bromoxynil and 2-methyl-4-chlorophenoxyacetic acid (MCPA) poisoning could be a bad combination. Clinical Toxicology, 56 (9), 1-3. doi: 10.1080/15563650.2018.1433299
Abd, Eman, Benson, Heather A. E., Roberts, Michael S. and Grice, Jeffrey E. (2018). Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting. Pharmaceutics, 10 (1) 19, 1-12. doi: 10.3390/pharmaceutics10010019
Chiew, Angela L., Wright, Daniel F. B., Roberts, Michael S. and Isbister, Geoffrey K. (2018). Response to ‘Comment on ‘‘Massive’ metformin overdose’ by Chiew et al.’. British Journal of Clinical Pharmacology, 84 (12), 2940-2941. doi: 10.1111/bcp.13747
Andréo-Filho, Newton, Bim, Antonio Vinicius Kosiski, Kaneko, Telma Mary, Kitice, Nidia Ayumi, Haridass, Isha N., Abd, Eman, Santos Lopes, Patricia, Thakur, Sachin S., Parekh, Harendra S., Roberts, Michael S., Grice, Jeffrey E., Benson, Heather A.E. and Leite-Silva, Vânia Rodrigues (2018). Development and Evaluation of Lipid Nanoparticles Containing Natural Botanical Oil for Sun Protection: Characterization and in vitro and in vivo Human Skin Permeation and Toxicity. Skin Pharmacology and Physiology, 31 (1), 1-9. doi: 10.1159/000481691
Jin, Wang, Liang, Xiaowen, Brooks, Anastasia, Futrega, Kathryn, Liu, Xin, Doran, Michael R., Simpson, Matthew J., Roberts, Michael S. and Wang, Haolu (2018). Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice. PeerJ, 2018 (12) e6072, e6072. doi: 10.7717/peerj.6072
Wang, Haolu, Li, Xinxing, Tse, Brian Wan-Chi, Yang, Haotian, Thorling, Camilla A., Liu, Yuxin, Touraud, Margaux, Chouane, Jean Batiste, Liu, Xin, Roberts, Michael S. and Liang, Xiaowen (2018). Indocyanine green-incorporating nanoparticles for cancer theranostics. Theranostics, 8 (5), 1227-1242. doi: 10.7150/thno.22872
Brooks, Anastasia, Futrega, Kathryn, Liang, Xiaowen, Hu, Xiaoling, Liu, Xin, Crawford, Darrell H. G., Doran, Michael R., Roberts, Michael S. and Wang, Haolu (2017). Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells. Stem Cells Translational Medicine, 7 (1), 78-86. doi: 10.1002/sctm.17-0209
Wang, Haolu, Thorling, Camilla A., Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Visualization and Modeling of the In Vivo Distribution of Mesenchymal Stem Cells. Current Protocols in Stem Cell Biology, 43 (1), 1-17. doi: 10.1002/cpsc.39
Chan, Betty S., Becker, Therese, Chiew, Angela L., Abdalla, Ahmed M., Robertson, Tom A., Liu, Xin, Roberts, Michael S. and Buckley, Nicholas A. (2017). Vasoplegic Shock Treated with Methylene Blue Complicated by Severe Serotonin Syndrome. Journal of Medical Toxicology, 14 (1), 100-103. doi: 10.1007/s13181-017-0637-1
Sime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2017). Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61 (11) e00311-17, e00311-17. doi: 10.1128/AAC.00311-17
Chiew, Angela L., Page, Colin B., Clancy, David, Mostafa, Ahmed, Roberts, Michael S. and Isbister, Geoffrey K. (2017). 2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion. Clinical Toxicology, 56 (5), 377-380. doi: 10.1080/15563650.2017.1385790
Gilbert, Alice V., Patel, Bhavini K., Roberts, Michael S., Williams, Desmond B., Crofton, Jackie H., Morris, Nicola M., Wallace, Joanna and Gilbert, Andrew L. (2017). An audit of medicines information quality in electronically generated discharge summaries – evidence to meet the Australian national safety and quality health service standards. Journal of Pharmacy Practice and Research, 47 (5), 355-364. doi: 10.1002/jppr.1256
Nastiti, Christofori M. R. R., Ponto, Thellie, Abd, Eman, Grice, Jeffrey E., Benson, Heather A. E. and Roberts, Michael S. (2017). Topical nano and microemulsions for skin delivery. Pharmaceutics, 9 (4) 37, 1-25. doi: 10.3390/pharmaceutics9040037
Cardon-Dunbar, Adeline, Robertson, Tom, Roberts, Michael S. and Isbister, Geoffrey K. (2017). Pramipexole Overdose Associated with Visual Hallucinations, Agitation and Myoclonus. Journal of Medical Toxicology, 13 (4), 343-346. doi: 10.1007/s13181-017-0615-7
Liu, Xin, Liang, Xiaowen, Wang, Haolu, Roberts, Darren M. and Roberts, Michael S. (2017). Multiphoton imaging for assessing renal disposition in acute kidney injury. SPIE Biophotonics Australasia, 10013. doi: 10.1117/12.2242964
Wang, Haolu, Zhang, Run, Bridle, Kim R., Jayachandran, Aparna, Thomas, James A., Zhang, Wenzhu, Yuan, Jingli, Xu, Zhi Ping, Crawford, Darrell H. G., Liang, Xiaowen, Liu, Xin and Roberts, Michael S. (2017). Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury. Scientific Reports, 7 (1) 45374, 45374. doi: 10.1038/srep45374
Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017). Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 (3) e01276, e01276-16. doi: 10.1128/AAC.01276-16
Roberts, M. S., Mohammed, Y., Pastore, M. N., Namjoshi, S., Yousef, S., Alinaghi, A., Haridass, I. N., Abd, E., Leite-Silva, V. R., Benson, H. A. E. and Grice, J. E. (2017). Topical and cutaneous delivery using nanosystems. Journal of Controlled Release, 247, 86-105. doi: 10.1016/j.jconrel.2016.12.022
Berling, Ingrid, Mostafa, Ahmed, Grice, Jeffrey E., Roberts, Michael S. and Isbister, Geoffrey K. (2017). Warfarin poisoning with delayed rebound toxicity. Journal of Emergency Medicine, 52 (2), 194-196. doi: 10.1016/j.jemermed.2016.05.068
Pastore, Michael N., Studier, Hauke, Bonder, Claudine S. and Roberts, Michael S. (2017). Non-invasive metabolic imaging of melanoma progression. Experimental Dermatology, 26 (7), 607-614. doi: 10.1111/exd.13274
Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Sinnollareddy, Mahipal G., Roger, Claire, Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of fluconazole in critically Ill patients. Antimicrobial Agents and Chemotherapy, 60 (11), 6550-6557. doi: 10.1128/AAC.01088-16
Jayaweera, Dushan, Islam, Shawkat, Gunja, Naren, Cowie, Chris, Broska, James, Poojara, Latesh, Roberts, Michael S. and Isbister, Geoffrey K. (2016). Chloroform ingestion causing severe gastrointestinal injury, hepatotoxicity and dermatitis confirmed with plasma chloroform concentrations. Clinical Toxicology, 55 (2), 1-4. doi: 10.1080/15563650.2016.1249795
Abd, Eman, Yousef , Shereen A., Pastore, Michael N., Telaprolu, Krishna, Mohammed, Yousuf H., Namjoshi, Sarika, Grice, Jeffrey E. and Roberts, Michael S. (2016). Skin models for the testing of transdermal drugs. Clinical Pharmacology: Advances and Applications, 8, 163-176. doi: 10.2147/CPAA.S64788
Holmes, Amy M., Lim, Julian, Studier, Hauke and Roberts, Michael S. (2016). Varying the morphology of silver nanoparticles results in differential toxicity against micro-organisms, HaCaT keratinocytes and affects skin deposition. Nanotoxicology, 10 (10), 1-12. doi: 10.1080/17435390.2016.1236993
Yousef, Shereen, Mohammed, Yousuf, Namjoshi, Sarika, Grice, Jeffrey, Sakran, Wedad and Roberts, Michael (2016). Mechanistic evaluation of hydration effects on the human epidermal permeation of salicylate esters. AAPS Journal, 19 (1), 1-11. doi: 10.1208/s12248-016-9984-0
Lamb, Thomas, Selvarajah, Liza R., Mohamed, Fahim, Jayamanne, Shaluka, Gawarammana, Indika, Mostafa, Ahmed, Buckley, Nicholas A., Roberts, Michael S. and Eddleston, Michael (2016). High lethality and minimal variation after acute self-poisoning with carbamate insecticides in Sri Lanka – implications for global suicide prevention. Clinical Toxicology, 54 (8), 624-631. doi: 10.1080/15563650.2016.1187735
Yousef, Shereen, Liu, Xin, Mostafa, Ahmed, Mohammed, Yousuf, Grice, Jeffrey E., Anissimov, Yuri G., Sakran, Wedad and Roberts, Michael S. (2016). Estimating maximal in vitro skin permeation flux from studies using non-sink receptor phase conditions. Pharmaceutical Research, 33 (9), 2180-2194. doi: 10.1007/s11095-016-1955-8
Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Ordonez Mejia, Jenny Lisette, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). Effect of obesity on the population pharmacokinetics of meropenem in critically ill patients. Antimicrobial Agents and Chemotherapy, 60 (8), 4577-4584. doi: 10.1128/AAC.00531-16
Leite-Silva, V. R., Sanchez, W. Y., Studier, H., Liu, D. C., Mohammed, Y. H., Holmes, A. M., Ryan, E. M., Haridass, I. N., Chandrasekaran, N. C., Becker, W., Grice, J. E., Benson, H. A. E. and Roberts, M. S. (2016). Human skin penetration and local effects of topical nano zinc oxide after occlusion and barrier impairment. European Journal of Pharmaceutics and Biopharmaceutics, 104 (4), 140-147. doi: 10.1016/j.ejpb.2016.04.022
Wang, Haolu, Liang, Xiaowen, Gravot, Germain, Thorling, Camilla A., Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2016). Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy. Journal of Biophotonics, 10 (1), 46-60. doi: 10.1002/jbio.201600083
Chandrasekaran, Navin Chandrakanth, Sanchez, Washington Y., Mohammed, Yousuf H., Grice, Jeffrey E., Roberts, Michael S. and Barnard, Ross T. (2016). Permeation of topically applied magnesium ions through human skin is facilitated by hair follicles. Magnesium Research, 29 (2), 35-42. doi: 10.1684/mrh.2016.0402
Leite-Silva, Vania R., Liu, David C., Sanchez, Washington Y., Studier, Hauke, Mohammed, Yousuf H., Holmes, Amy, Becker, Wolfgang, Grice, Jeffrey E., Benson, Heather A. E. and Roberts, Michael S. (2016). Effect of flexing and massage on in vivo human skin penetration and toxicity of zinc oxide nanoparticles. Nanomedicine, 11 (10), 1193-1205. doi: 10.2217/nnm-2016-0010
Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 (3) dkv412, 696-702. doi: 10.1093/jac/dkv412
Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016). SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 (1) 103, 103.1-103.8. doi: 10.1186/s12879-016-1421-6
Wang, Haolu, Liang, Xiaowen, Xu, Zhi Ping, Crawford, Darrell H. G, Liu, Xin and Roberts, Michael S. (2016). A physiologically based kinetic model for elucidating the in vivo distribution of administered mesenchymal stem cells. Scientific Reports, 6 (1) 22293, e22293.1-e22293.12. doi: 10.1038/srep22293
Holmes, Amy M., Song, Zhen, Moghimi, Hamid R. and Roberts, Michael S. (2016). Relative penetration of zinc oxide and zinc ions into human skin after application of different zinc oxide formulations. ACS Nano, 10 (2), 1810-1819. doi: 10.1021/acsnano.5b04148
Liang, Xiaowen, Wang, Haolu, Grice, Jeffrey E., Li, Li, Liu, Xin, Xu, Zhi Ping and Roberts, Michael S. (2016). Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles. Nano Letters, 16 (2), 939-945. doi: 10.1021/acs.nanolett.5b03854
Page, Colin B., Mostafa, Ahmed, Saiao, Ana, Grice, Jeffrey E., Roberts, Michael S. and Isbister, Geoffrey K. (2016). Cardiovascular toxicity with levetiracetam overdose. Clinical Toxicology, 54 (2), 152-154. doi: 10.3109/15563650.2015.1115054
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016). In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 (2), 827-832. doi: 10.1128/AAC.02461-15
Isbister, Geoffrey K., Ang, Karyn, Gorman, Kieron, Cooper, Joyce, Mostafa, Ahmed and Roberts, Michael S. (2016). Zero-order metoprolol pharmacokinetics after therapeutic doses: severe toxicity and cardiogenic shock. Clinical Toxicology, 54 (9), 881-885. doi: 10.1080/15563650.2016.1209768
Liang, Xiaowen, Wang, Haolu, Zhu, Yian, Zhang, Run, Cogger, Victoria C., Liu, Xin, Xu, Zhi Ping, Grice, Jeffrey E. and Roberts, Michael S. (2016). Short- and long-term tracking of anionic ultrasmall nanoparticles in kidney. Acs Nano, 10 (1), 387-395. doi: 10.1021/acsnano.5b05066
Abd, Eman, Namjoshi, Sarika, Mohammed, Yousuf H., Roberts, Michael S. and Grice, Jeffrey E. (2016). Synergistic skin penetration enhancer and nanoemulsion formulations promote the human epidermal permeation of caffeine and naproxen. Journal of Pharmaceutical Sciences, 105 (1), 212-220. doi: 10.1002/jps.24699
Abd, Eman, Roberts, Michael S. and Grice, Jeffrey E. (2015). A comparison of the penetration and permeation of caffeine into and through human epidermis after application in various vesicle formulations. Skin Pharmacology and Physiology, 29 (1), 24-30. doi: 10.1159/000441040
Sime, F. B., Roberts, M. S. and Roberts, J. A. (2015). Optimization of dosing regimens and dosing in special populations. Clinical Microbiology and Infection, 21 (10), 886-893. doi: 10.1016/j.cmi.2015.05.002
Sime, Fekade Bruck., Roberts, Michael S., Tiong, Ing Soo., Gardner, Julia H., Lehman, Sheila., Peake, Sandra L., Hahn, Uwe., Warner, Morgyn S. and Roberts, Jason A. (2015). Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies. Antimicrobial Agents and Chemotherapy, 59 (9), 5463-5469. doi: 10.1128/AAC.00389-15
Michael, Adam P., Mostafa, Ahmed, Cooper, Joyce M., Grice, Jeffrey, Roberts, Michael S. and Isbister, Geoffrey K. (2015). The pharmacokinetics and pharmacodynamics of severe aldicarb toxicity after overdose. Clinical Toxicology, 53 (7), 633-635. doi: 10.3109/15563650.2015.1054504
Downes, Michael A., Berling, Ingrid L., Mostafa, Ahmed, Grice, Jeffrey, Roberts, Michael S. and Isbister, Geoffrey K. (2015). Acute behavioural disturbance associated with phenibut purchased via an internet supplier. Clinical Toxicology, 53 (7), 636-638. doi: 10.3109/15563650.2015.1059945
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015). Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 (1), 121-124. doi: 10.1016/j.ijantimicag.2015.02.017
Berling, Ingrid, Buckley, Nicholas A., Mostafa, Ahmed, Downes, Michael A., Grice, Jeffrey, Medley, Gregory, Roberts, Michael S. and Isbister, Geoffrey K. (2015). 2-Methyl-4-chlorophenoxyacetic acid and bromoxynil herbicide death. Clinical Toxicology, 53 (5), 486-488. doi: 10.3109/15563650.2015.1030025
Sime, Fekade B., Roberts, Michael S., Tiong, Ing S., Gardner, Julia H., Lehman, Sheila, Peake, Sandra L., Hahn, Uwe, Warner, Morgyn S. and Roberts, Jason A. (2015). Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial. Journal of Antimicrobial Chemotherapy, 70 (8) dkv123, 2369-2375. doi: 10.1093/jac/dkv123
Pastore, Michael N, Kalia, Yogeshvar N, Horstmann, Michael and Roberts, Michael S (2015). Transdermal patches: History, development and pharmacology. British Journal of Pharmacology, 172 (9), 2179-2209. doi: 10.1111/bph.13059
Arab, Hossein-Ali, Walker, Neal I., Cheung, Kee, Hickman, Peter E., Potter, Jolia M., Kadkhodaee, Mehri and Roberts, Michael S. (2015). Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury. Journal of Investigative Surgery, 28 (2), 77-85. doi: 10.3109/08941939.2014.971205
Mahmood, Adnan H., Liu, Xin, Grice, Jeffrey E., Medley, Gregory A. and Roberts, Michael S. (2015). Using deconvolution to understand the mechanism for variable plasma concentration-time profiles after intramuscular injection. International Journal of Pharmaceutics, 481 (1-2), 71-78. doi: 10.1016/j.ijpharm.2015.01.046
Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo and RENAL Replacement Therapy Study Investigators (2015). A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19 (84) 84, 84. doi: 10.1186/s13054-015-0818-8
Wang, Haolu, Liang, Xiaowen, Mohammed, Yousuf H., Thomas, James A., Bridle, Kim R., Thorling, Camilla A., Grice, Jeffrey E., Xu, Zhi Ping, Liu, Xin, Crawford, Darrell H. G. and Roberts, Michael S. (2015). Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging. Biomedical Optics Express, 6 (3), 780-792. doi: 10.1364/BOE.6.000780
Wang, Haolu, Thorling, Camilla A., Liang, Xiaowen, Bridle, Kim R., Grice, Jeffrey E., Zhu, Yian, Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin and Roberts, Michael S. (2015). Diagnostic imaging and therapeutic application of nanoparticles targeting the liver. Journal of Materials Chemistry B, 3 (6), 939-958. doi: 10.1039/C4TB01611D
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Robertson, Thomas A., Peake, Sandra L. and Roberts, Jason A. (2015). Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45 (2), 192-195. doi: 10.1016/j.ijantimicag.2014.08.013
Udy, Andrew A., Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C., Patel, Kashyap, Kirkpatrick, Carl M. J., Kruger, Peter S., Paterson, David L., Roberts, Michael S. and Roberts, Jason A. (2015). Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical Care, 19 (28) 28, 1-9. doi: 10.1186/s13054-015-0750-y
Reeve E., Andrews J.M., Wiese M.D., Hendrix I., Roberts M.S. and Shakib S. (2015). Feasibility of a Patient-Centered Deprescribing Process to Reduce Inappropriate Use of Proton Pump Inhibitors. Annals of Pharmacotherapy, 49 (1), 29-38. doi: 10.1177/1060028014558290
Thorling C.A., Jin L., Weiss M., Crawford D., Liu X., Burczynski F.J., Liu D., Wang H. and Roberts M.S. (2015). Assessing steatotic liver function after ischemia-reperfusion injury by in vivo multiphoton imaging of fluorescein disposition. Drug Metabolism and Disposition, 43 (1), 154-162. doi: 10.1124/dmd.114.060848
Skinner, Kirsty, Saiao, Ana, Mostafa, Ahmed, Soderstrom, Jessamine, Medley, Gregory, Roberts, Michael S. and Isbister, Geoffrey K. (2015). Isoniazid poisoning: Pharmacokinetics and effect of hemodialysis in a massive ingestion. Hemodialysis International, 19 (4), E37-E40. doi: 10.1111/hdi.12293
Gordon, Sarah, Daneshian, Mardas, Bouwstra, Joke, Caloni, Francesca, Constant, Samuel, Davies, Donna E., Dandekar, Gudrun, Guzman, Carlos A., Fabian, Eric, Haltner, Eleonore, Hartung, Thomas, Hasiwa, Nina, Hayden, Patrick, Kandarova, Helena, Khare, Sangeeta, Krug, Harald F., Kneuer, Carsten, Leist, Marcel, Lian, Guoping, Marx, Uwe, Metzger, Marco, Ott, Katharina, Prieto, Pilar, Roberts, Michael S., Roggen, Erwin L., Tralau, Tewes, van den Braak, Claudia, Walles, Heike and Lehr, Claus-Michael (2015). Non-Animal Models of Epithelial Barriers (Skin, Intestine and Lung) in Research, Industrial Applications and Regulatory Toxicology. Altex-Alternatives to Animal Experimentation, 32 (4), 327-378. doi: 10.14573/altex.1510051
McNeilly, Celia L., Crichton, Michael L., Primiero, Clare A., Frazer, Ian H., Roberts, Michael S. and Kendall, Mark A. F. (2014). Microprojection arrays to immunise at mucosal surfaces. Journal of Controlled Release, 196, 252-260. doi: 10.1016/j.jconrel.2014.09.028
Liu, Xin, Kruger, Peter, Maibach, Howard, Colditz, Paul B. and Roberts, Michael S. (2014). Using skin for drug delivery and diagnosis in the critically ill. Advanced Drug Delivery Reviews, 77, 40-49. doi: 10.1016/j.addr.2014.10.004
Reeve, Emily, Shakib, Sepehr, Hendrix, Ivanka, Roberts, Michael S. and Wiese, Michael D. (2014). The benefits and harms of deprescribing. Medical Journal of Australia, 201 (7), 386-389. doi: 10.5694/mja13.00200
Wunnapuk, Klintean, Mohammed, Fahim, Gawarammana, Indika, Liu, Xin, Verbeeck, Roger K., Buckley, Nicholas A., Roberts, Michael S. and Musuamba, Flora T. (2014). Prediction of paraquat exposure and toxicity in clinically ill poisoned patients: a model based approach. British Journal of Clinical Pharmacology, 78 (4), 855-866. doi: 10.1111/bcp.12389
Reeve, Emily, Shakib, Sepehr, Hendrix, Ivanka, Roberts, Michael S. and Wiese, Michael D. (2014). Review of deprescribing processes and development of an evidence-based, patient-centred deprescribing process. British Journal of Clinical Pharmacology, 78 (4), 738-747. doi: 10.1111/bcp.12386
Thorling, Camilla A., Crawford, Darrell, Burczynski, Frank J., Liu, Xin, Liau, Ian and Roberts, Michael S. (2014). Multiphoton microscopy in defining liver function. Journal of Biomedical Optics, 19 (9) 090901, 90901-090901. doi: 10.1117/1.JBO.19.9.090901
Mohammed, Yousuf H., Yamada, Miko, Lin, Lynlee L., Grice, Jeffrey E., Roberts, Michael S., Raphael, Anthony P., Benson, Heather A. E. and Prow, Tarl W. (2014). Microneedle enhanced delivery of cosmeceutically relevant peptides in human skin. PLoS One, 9 (7) e101956, e101956.1-e101956.9. doi: 10.1371/journal.pone.0101956
Chandrasekaran, Navin Chandrakanth, Weir, Christopher, Alfraji, Sumaya, Grice, Jeff, Roberts, Michael S. and Barnard, Ross T. (2014). Effects of magnesium deficiency - More than skin deep. Experimental Biology and Medicine, 239 (10), 1280-1291. doi: 10.1177/1535370214537745
Sime, Fekade Bruck, Roberts, Michael S., Roberts, Jason A. and Robertson, Thomas A. (2014). Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. Journal of Chromatography B, 960, 134-144. doi: 10.1016/j.jchromb.2014.04.029
Kuswahyuning, Rina and Roberts, Michael S. (2014). Concentration dependency in nicotine skin penetration flux from aqueous solutions reflects vehicle induced changes in nicotine stratum corneum retention. Pharmaceutical Research, 31 (6), 1501-1511. doi: 10.1007/s11095-013-1256-4
Krishnan, Gayathri, Roberts, Michael S., Grice, Jeffrey, Anissimov, Yuri G., Moghimi, Hamid R. and Benson, Heather A. E. (2014). Iontophoretic skin permeation of peptides: an investigation into the influence of molecular properties, iontophoretic conditions and formulation parameters. Drug Delivery and Translational Research, 4 (3), 222-232. doi: 10.1007/s13346-013-0181-8
Roberts, Jason A., Udy, Andrew A., Jarrett, Paul, Wallis, Steven C., Hope, William W., Sharma, Raman, Kirkpatrick, Carl M. J., Kruger, Peter S., Roberts, Michael S. and Lipman, Jeffrey (2014). Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients. Journal of Antimicrobial Chemotherapy, 70 (5) dku564, 1495-1502. doi: 10.1093/jac/dku564
Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 (5) dkt523, 1416-1423. doi: 10.1093/jac/dkt523
Thorling, Camilla A., Roberts, Michael S., Liu, Xin, Fletcher, Linda M., Crawford, Darrell and Burczynski, Frank J. (2014). Effects of long-term hepatic ischemia-reperfusion injury on the function of P-glycoprotein in vivo in rats. Journal of Pharmacy and Pharmaceutical Sciences, 17 (1), 121-135. doi: 10.18433/J33C7B
Wunnapuk, Klintean, Liu, Xin, Gobe, Glenda C., Endre, Zoltan H., Peake, Philip W., Grice, Jeffrey E., Roberts, Michael S. and Buckley, Nicholas A. (2014). Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance. Toxicology Letters, 225 (3), 467-478. doi: 10.1016/j.toxlet.2014.01.018
Wunnapuk, Klintean, Gobe, Glenda, Endre, Zoltan, Peake, Philip, Grice, Jeffrey E., Roberts, Michael S., Buckley, Nicholas A. and Liu, Xin (2014). Use of a glyphosate-based herbicide-induced nephrotoxicity model to investigate a panel of kidney injury biomarkers. Toxicology Letters, 225 (1), 192-200. doi: 10.1016/j.toxlet.2013.12.009
Sime, Fekade Bruck, Roberts, Michael S., Warner, Morgyn S., Hahn, Uwe, Robertson, Thomas A., Yeend, Sue, Phay, Andy, Lehman, Sheila, Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2014). Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy. Antimicrobial Agents and Chemotherapy, 58 (6), 3533-3537. doi: 10.1128/AAC.02340-14
Liang X., Grice J.E., Zhu Y., Liu D., Sanchez W.Y., Li Z., Crawford D.H.G., Le Couteur D.G., Cogger V.C., Liu X., Xu Z.P. and Roberts M.S. (2014). Intravital multiphoton imaging of the selective uptake of water-dispersible quantum dots into sinusoidal liver cells. Small, 11 (14), 1711-1720. doi: 10.1002/smll.201402698
Wunnapuk, Klintean, Liu, Xin, Peake, Philip, Gobe, Glenda, Endre, Zoltan, Grice, Jeffrey E., Roberts, Michael S. and Buckley, Nicholas A. (2013). Renal biomarkers predict nephrotoxicity after paraquat. Toxicology Letters, 222 (3), 280-288. doi: 10.1016/j.toxlet.2013.08.003
Liang, Xiao Wen, Xu, Zhi Ping, Grice, Jeffrey, Zvyagin, Andrei V., Roberts, Michael S. and Liu, Xin (2013). Penetration of Nanoparticles into Human Skin. Current Pharmaceutical Design, 19 (35), 6353-6366. doi: 10.2174/1381612811319350011
Reeve, Emily, To, Josephine, Hendrix, Ivanka, Shakib, Sepehr, Roberts, Michael S. and Wiese, Michael D. (2013). Patient barriers to and enablers of deprescribing: a systematic review. Drugs and Aging, 30 (10), 793-807. doi: 10.1007/s40266-013-0106-8
Reeve, Emily, Wiese, Michael D., Hendrix, Ivanka, Roberts, Michael S. and Shakib, Sepeh (2013). People's attitudes, beliefs, and experiences regarding polypharmacy and willingness to deprescribe. Journal of the American Geriatrics Society, 61 (9), 1508-1514. doi: 10.1111/jgs.12418
Weiss, Michael, Liu, Xin, Thorling, Camilla A. and Roberts, Michael S. (2013). Functional characterization of hepatic transporters using intravital microscopy. European Journal of Pharmaceutical Sciences, 49 (5), 845-849. doi: 10.1016/j.ejps.2013.06.006
Mahmood, Adnan, Grice, Jeffrey E., Roberts, Michael S. and Prow, Tarl W. (2013). Feasibility of multiphoton microscopy-based quantification of antibiotic uptake into neutrophil granulocytes. Journal of Biomedical Optics, 18 (7) 076003, 076003.1-076003.6. doi: 10.1117/1.JBO.18.7.076003
Song, Zhen, Anissimov, Yuri G., Zhao, Jiangbo, Nechaev, Andrei V., Nadort, Annemarie, Jin, Dayong, Prow, Tarl W., Roberts, Michael S. and Zvyagin, Andrei V. (2013). Background free imaging of upconversion nanoparticle distribution in human skin. Journal of Biomedical Optics, 18 (6) 61215, 061215.1-061215.10. doi: 10.1117/1.JBO.18.6.061215
Leite-Silva, Vania R., Le Lamer, Marina, Sanchez, Washington Y., Liu, David C., Sanchez, Washington H., Morrow, Isabel, Martin, Darren, Silva, Heron D. T., Prow, Tan L. W., Grice, Jeffrey E. and Roberts, Michael S. (2013). The effect of formulation on the penetration of coated and uncoated zinc oxide nanoparticles into the viable epidermis of human skin in vivo. European Journal of Pharmaceutics and Biopharmaceutics, 84 (2), 297-308. doi: 10.1016/j.ejpb.2013.01.020
Sanchez, Washington Y., Obispo, Clara, Ryan, Elizabeth, Grice, Jeffrey E. and Roberts, Michael S. (2013). Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging. Journal of Biomedical Optics, 18 (6) 69802, 61217.1-61217.12. doi: 10.1117/1.JBO.18.6.061217
Liu, Xin, Jin, Lu, Upham, John W. and Roberts, Michael S. (2013). The development of models for the evaluation of pulmonary drug disposition. Expert Opinion On Drug Metabolism & Toxicology, 9 (4), 487-505. doi: 10.1517/17425255.2013.754009
Kruger, Peter, Bailey, Michael, Bellomo, Rinaldo, Cooper, David James, Harward, Meg, Higgins, Alisa, Howe, Belinda, Jones, Darryl, Joyce, Chris, Kostner, Karam, McNeil, John, Nichol, Alistair, Roberts, Michael S., Syres, Gillian, Venkatesh, Bala and ANZ-STATInS Investigators–ANZICS Clinical Trials Group (2013). A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis. American Journal of Respiratory and Critical Care Medicine, 187 (7), 743-750. doi: 10.1164/rccm.201209-1718OC
Dancik, Yuri, Favre, Amandine, Loy, Chong Jin, Zvyagin, Andrei V. and Roberts, Michael S. (2013). Use of multiphoton tomography and fluorescence lifetime imaging to investigate skin pigmentation in vivo. Journal of Biomedical Optics, 18 (2) 026022, 26022-026022. doi: 10.1117/1.JBO.18.2.026022
Anissimov, Yuri G., Jepps, Owen G., Dancik, Yuri and Roberts, Michael S. (2013). Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes. Advanced Drug Delivery Reviews, 65 (2), 169-190. doi: 10.1016/j.addr.2012.04.009
Krishnan, Gayathri, Grice, Jeffrey E., Roberts, Michael S., Benson, Heather A. E. and Prow, Tarl W. (2013). Enhanced sonophoretic delivery of 5-aminolevulinic acid: preliminary human ex vivo permeation data. Skin Research and Technology, 19 (1), e283-e289. doi: 10.1111/j.1600-0846.2012.00640.x
Reeve, Emily, Shakib, Sepehr, Hendrix, Ivanka, Roberts, Michael S. and Wiese, Michael D. (2013). Development and validation of the patients' attitudes towards deprescribing (PATD) questionnaire. International Journal of Clinical Pharmacy, 35 (1), 51-56. doi: 10.1007/s11096-012-9704-5
Jepps, Owen G., Dancik, Yuri, Anissimov, Yuri G. and Roberts, Michael S. (2013). Modeling the human skin barrier - towards a better understanding of dermal absorption. Advanced Drug Delivery Reviews, 65 (2), 152-168. doi: 10.1016/j.addr.2012.04.003
Thorling, Camilla A., Liu, Xin, Burczynski, Frank J., Fletcher, Linda M., Roberts, Michael S. and Sanchez, Washington Y. (2013). Intravital multiphoton microscopy can model uptake and excretion of fluorescein in hepatic ischemia-reperfusion injury. Journal of Biomedical Optics, 18 (10) 101306, 1-12. doi: 10.1117/1.JBO.18.10.101306
Arab, Hossein-Ali, Cheung, Kee, Hickman, Peter E., Potter, Julia M., Walker, Neal I. and Roberts, Michael S. (2013). A comparison of hepatic ischemia/hypoxia-reperfusion injury models. Journal of Pharmacological and Toxicological Methods, 68 (3), 349-356. doi: 10.1016/j.vascn.2013.03.002
Mutalik, S., Parekh, H. S., Anissimov, Y. G., Grice, J. E. and Roberts, M. S. (2013). Iontophoresis-Mediated Transdermal Permeation of Peptide Dendrimers across Human Epidermis. Skin Pharmacology and Physiology, 26 (3), 127-138. doi: 10.1159/000348469
Roberts, M. S. (2013). Solute-vehicle-skin interactions in percutaneous absorption: the principles and the people. Skin Pharmacology and Physiology, 26 (4-6), 356-370. doi: 10.1159/000353647
Zhang, Qian, Li, Peng, Liu, David and Roberts, Michael S. (2013). Effect of vehicles on the maximum transepidermal flux of similar size phenolic compounds. Pharmaceutical Research, 30 (1), 32-40. doi: 10.1007/s11095-012-0846-x
Sanchez, Washington Y., Obispo, Clara, Ryan, Elizabeth, Grice, Jeffrey E. and Roberts, Michael S. (2012). Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging (vol 18, 061217, 2013). Journal of Biomedical Optics, 18 (6) 69802, 069802-069802. doi: 10.1117/1.JBO.18.6.069802
Gilbert, Alice V., Patel, Bhavini, Morrow, Melanie, Williams, Desmond, Roberts, Michael S. and Gilbert, Andrew L. (2012). Providing community-based health practitioners with timely and accurate discharge medicines information. BMC Health Services Research, 12 (1) 453, 453.1-453.7. doi: 10.1186/1472-6963-12-453
Wiechers, J. W., Watkinson, A. C., Cross, S. E. and Roberts, M. S. (2012). Predicting skin penetration of actives from complex cosmetic formulations: an evaluation of inter formulation and inter active effects during formulation optimization for transdermal delivery. International Journal of Cosmetic Science, 34 (6), 525-535. doi: 10.1111/ics.12001
Sanchez, Washington Y., Obispo, Clara, Ryan, Elizabeth, Grice, Jeffrey E. and Roberts, Michael S. (2012). Erratum: Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging (J. Biomed. Opt. (2013) 18 (061217)). Journal of Biomedical Optics, 17 (12) 129801 doi: 10.1117/1.JBO.17.12.129801
Weiss, Michael, Li, Peng and Roberts, Michael S. (2012). Estimation of sinusoidal flow heterogeneity in normal and diseased rat livers from Tracer Dilution Data Using a Fractal Model. Microcirculation, 19 (8), 723-728. doi: 10.1111/j.1549-8719.2012.00208.x
Anissimov, Yuri G., Zhao, Xin, Roberts, Michael S. and Zvyagin, Andrei V. (2012). Fluorescence recovery after photo-bleaching as a method to determine local diffusion coefficient in the stratum corneum. International Journal of Pharmaceutics, 435 (1), 93-97. doi: 10.1016/j.ijpharm.2012.01.055
Li, Peng, Weiss, Michael and Roberts, Michael S. (2012). Hepatic interaction between quinidine and digoxin: role of inhibition of sinusoidal Na+/K+ ATPase digoxin binding. European Journal of Pharmaceutical Sciences, 47 (2), 506-511. doi: 10.1016/j.ejps.2012.07.008
Leite-Silva, Vania Rodrigues, de Almeida, Mariana Mandelli, Fradin, Aurelie, Grice, Jeffrey Ernest and Roberts, Michael Stephen (2012). Delivery of drugs applied topically to the skin. Expert Review of Dermatology, 7 (4), 383-397. doi: 10.1586/edm.12.32
Sime, Fekade Bruck, Roberts, Michael S., Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2012). Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A systematic review. Annals of Intensive Care, 2 (1) 35, 35.1-35.11. doi: 10.1186/2110-5820-2-35
Kaur, Sukhpreet, Roberts, Jason A. and Roberts, Michael S. (2012). Evaluation of medication-related problems in medication reviews: a comparative perspective. Annals of Pharmacotherapy, 46 (7-8), 972-982. doi: 10.1345/aph.1Q694
Liu, Xin, Thorling, Camilla A., Jin, Lu and Roberts, Michael S. (2012). Intravital multiphoton imaging of rhodamine 123 in the rat liver after intravenous dosing. IntraVital, 1 (1), 54-59. doi: 10.4161/intv.21450
Li, Peng, Robertson, Thomas A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G., Weiss, Michael and Roberts, Michael S. (2012). Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage. Pharmaceutical Research, 29 (6), 1658-1669. doi: 10.1007/s11095-012-0690-z
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). beta-Lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: A structured review. Clinical and Experimental Pharmacology and Physiology, 39 (6), 489-496. doi: 10.1111/j.1440-1681.2012.05715.x
Liu, Xin, Kruger, Peter S., Weiss, Michael and Roberts, Michael S. (2012). The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis. British Journal of Clinical Pharmacology, 73 (5), 741-749. doi: 10.1111/j.1365-2125.2011.04149.x
Roberts, Darren M., Roberts, Jason A., Roberts, Michael S., Liu, Xin, Nair, Priya, Cole, Louise, Lipman, Jeffrey, Bellomo, Rinaldo and on behalf of the RENAL Replacement Therapy Study Investigators (2012). Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study. Critical Care Medicine, 40 (5), 1523-1528. doi: 10.1097/CCM.0b013e318241e553
Dancik, Yuri, Anissimov, Yuri G., Jepps, Owen G. and Roberts, Michael S. (2012). Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application. British Journal of Clinical Pharmacology, 73 (4), 564-578. doi: 10.1111/j.1365-2125.2011.04128.x
Prow, Tarl W., Monteiro-Riviere, Nancy A., Inman, Alfred O., Grice, Jeffrey E., Chen, Xianfeng, Zhao, Xin, Sanchez, Washington H., Gierden, Audrey, Kendall, Mark A. F., Zvyagin, Andrei V., Erdmann, Detlev, Rivierer, Jim E. and Roberts, Michael S. (2012). Quantum dot penetration into viable human skin. Nanotoxicology, 6 (2), 173-185. doi: 10.3109/17435390.2011.569092
Mahmood, Adnan H., Medley, Gregory A., Grice, Jeffrey E., Liu, Xin and Roberts, Michael S. (2012). Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection. Journal of Pharmaceutical and Biomedical Analysis, 62, 220-223. doi: 10.1016/j.jpba.2012.01.007
Kruger, Peter S., Joyce, Christopher J., Harward, Meg L., Jones, Mark A., Kostner, Karam M., Roberts, Michael S. and Venkatesh, Bala (2012). Continuation of Statin Therapy in patients with presumed infection. American Journal of Respiratory and Critical Care Medicine, 185 (4), 456-457. doi: 10.1164/ajrccm.185.4.456a
Liu, David C., Raphael, Anthony P., Sundh, Daniel, Grice, Jeffrey E., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2012). The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences. Journal of Nanomaterials, 2012 721706, 72176.1-72176.8. doi: 10.1155/2012/721706
Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review. International Journal of Antimicrobial Agents, 39 (1), 1-10. doi: 10.1016/j.ijantimicag.2011.07.013
Song, Zhen, Kelf, Timothy A., Sanchez, Washington H., Roberts, Michael S., Ricka, Jaro, Frenz, Martin and Zvyagin, Andrei V. (2011). Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport. Biomedical Optics Express, 2 (12), 3321-3333. doi: 10.1364/BOE.2.003321
Liu, Xin, Grice, Jeff E., Lademann, Juergen, Otberg, Nina, Trauer, Sindy, Patzelt, Alexa and Roberts, Michael S. (2011). Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man. British Journal of Clinical Pharmacology, 72 (5), 768-774. doi: 10.1111/j.1365-2125.2011.04022.x
Lin, Lynlee L., Grice, Jeffrey E., Butler, Margaret K., Zvyagin, Andrei V., Becker, Wolfgang, Robertson, Thomas A., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2011). Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin. Pharmaceutical Research, 28 (11), 2920-2930. doi: 10.1007/s11095-011-0515-5
Thorling, Camilla A., Liu, Xin, Burczynski, Frank J., Fletcher, Linda M., Gobe, Glenda C. and Roberts, Michael S. (2011). Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats. Journal of Biomedical Optics, 16 (11) 116011, 116011-1160118. doi: 10.1117/1.3647597
Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011). Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 (11), 5238-5242. doi: 10.1128/AAC.05033-11
Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011). Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 (11), 1431-1440. doi: 10.1517/17425255.2011.615309
Wunnapuk, Klintean, Medley, Gregory A., Liu, Xin, Grice, Jeffrey E., Jayasinghe, Sudheera, Gawarammana, Indika, Buckley, Nicholas A. and Roberts, Michael S. (2011). Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 879 (28), 3047-3052. doi: 10.1016/j.jchromb.2011.09.008
Mitragotri, Samir, Anissimov, Yuri G., Bunge, Annette L., Frasch, H. Frederick, Guy, Richard H., Hadgraft, Jonathan, Kasting, Gerald B., Lane, Majella E. and Roberts, Michael S. (2011). Mathematical models of skin permeability: An overview. International Journal of Pharmaceutics, 418 (1), 115-129. doi: 10.1016/j.ijpharm.2011.02.023
Anissimov, Yuri G. and Roberts, Michael Stephen (2011). Modelling dermal drug distribution after topical application in human. Pharmaceutical Research, 28 (9), 2119-2129. doi: 10.1007/s11095-011-0437-2
Labouta, H. I., Liu, D. C., Lin, L. L., Butler, M. K., Grice, J. E., Raphael, A. P., Kraus, T., El-Khordagui, L. K., Soyer, H. P., Roberts, M. S., Schneider, M. and Prow, T. W. (2011). Gold nanoparticle penetration and reduced metabolism in human skin by toluene. Pharmaceutical Research, 28 (11), 2931-2944. doi: 10.1007/s11095-011-0561-z
Zhou, Fang, Zhang, Jingwei, Li, Peng, Niu, Fang, Wu, Xiaolan, Wang, Guangji and Roberts, Michael S. (2011). Toward a new age of cellular pharmacokinetics in drug discovery. Drug Metabolism Reviews, 43 (3), 335-345. doi: 10.3109/03602532.2011.560607
Thorling, Camilla A., Dancik, Yuri, Hupple, Clinton W., Medley, Gregory, Liu, Xin, Zvyagin, Andrei V., Robertson, Tom A., Burczynski, Frank J. and Roberts, Michael S. (2011). Multiphoton microscopy and fluorescence lifetime imaging provide a novel method in studying drug distribution and metabolism in the rat liver in vivo. Journal of Biomedical Optics, 16 (8) 086013, 086013-1-086013-7. doi: 10.1117/1.3614473
Mostafa, Ahmed, Medley, Gregory, Roberts, Darren M., Mohamed, Mosaad Sayed, Elshanawani, Abdalla A., Roberts, Michael S. and Liu, Xin (2011). Simultaneous quantification of carbamate insecticides in human plasma by liquid chromatography/tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 879 (23), 2234-2238. doi: 10.1016/j.jchromb.2011.06.006
Zhang, Qian, Li, Peng and Roberts, Michael S. (2011). Maximum transepidermal flux for similar size phenolic compounds is enhanced by solvent uptake into the skin. Journal of Controlled Release, 154 (1), 50-57. doi: 10.1016/j.jconrel.2011.04.018
Fanning, Kent J., Robertson, Thomas A., Prins, Johannes B. and Roberts, Michael S. (2011). Changes in antibiotic distribution due to pancreatitis. Antimicrobial Agents and Chemotherapy, 55 (6), 3008-3011. doi: 10.1128/AAC.00416-10
Prow, Tarl W., Grice, Jeffrey E., Lin, Lynlee L., Faye, Rokhaya, Butler, Margaret, Becker, Wolfgang, Wurm, Elisabeth M. T., Yoong, Corinne, Robertson, Thomas A., Soyer, H. Peter and Roberts, Michael S. (2011). Nanoparticles and microparticles for skin drug delivery. Advanced Drug Delivery Reviews, 63 (6), 470-491. doi: 10.1016/j.addr.2011.01.012
Liu, Xin, Kruger, Peter S. and Roberts, Michael S. (2011). How to measure pharmacokinetics in critically ill patients?. Current Pharmaceutical Biotechnology, 12 (12), 2037-2043. doi: 10.2174/138920111798808239
Roberts, Michael S., Dancik, Yuri, Prow, Tarl W., Thorling, Camilla A., Lin, Lynlee L., Grice, Jeffrey E., Robertson, Thomas A., Koenig, Karsten and Becker, Wolfgang (2011). Non-invasive imaging of skin physiology and percutaneous penetration using fluorescence spectral and lifetime imaging with multiphoton and confocal microscopy. European Journal of Pharmaceutics and Biopharmaceutics, 77 (3), 469-488. doi: 10.1016/j.ejpb.2010.12.023
König, Karsten, Raphael, Anthony P., Lin, Li, Grice, Jeffrey E., Soyer, H. Peter, Breunig, H. Georg, Roberts, Michael S. and Prow, Tarl W. (2011). Applications of multiphoton tomographs and femtosecond laser nanoprocessing microscopes in drug delivery research. Advanced Drug Delivery Reviews, 63 (4-5), 388-404. doi: 10.1016/j.addr.2011.03.002
Li, Peng, Robertson, Thomas A., Thorling, Camilla A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2011). Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. Drug Metabolism and Disposition, 39 (4), 571-579. doi: 10.1124/dmd.110.036806
Roberts, Roberts, Darren M., Wilks, Martin F., Roberts, Michael S., Swaminathan, Ramasamyiyer, Mohamed, Fahim, Dawson, Andrew H. and Buckley, Nick A. (2011). Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning. Toxicology Letters, 202 (1), 69-74. doi: 10.1016/j.toxlet.2011.01.024
Kruger, Peter S., Harward, Meg L., Jones, Mark A., Joyce, Christopher J., Kostner, Karam M., Roberts, Michael S. and Venkateshm Bala (2011). Continuation of statin therapy in patients with presumed infection: A randomized controlled trial. American Journal of Respiraty and Critical Care Medicine, 183 (6), 774-781. doi: 10.1164/rccm.201006-0955OC
Roberts, Jason A., Roberts, Michael S., Semark, Andrew, Udy, Andrew A., Kirkpatrick, Carl M.J., Paterson, David L., Roberts, Matthew J., Kruger, Peter and Lipman, Jeffrey (2011). Antibiotic dosing in the 'at risk' critically ill patient: linking pathophysiology with pharmacokinetics/pharmacodynamics in sepsis and trauma patients. BMC Anesthesiology, 11 (1) 3, 3.1-3.7. doi: 10.1186/1471-2253-11-3
Davies, Paul G., Venkatesh, Balasubramanian, Morgan, Thomas J., Presneill, Jeffrey J., Kruger, Peter S., Thomas, Bronwyn J., Roberts, Michael S. and Mundy, Julie (2011). Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution. Critical Care, 15 (1) R21, R21-1-R21-8. doi: 10.1186/cc9966
Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2011). Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 1. pharmind: Die Pharmazeutische Industrie, 73 (1), 174-177.
Roberts, Michael S., Liu, Xin, Zou, Yuhong, Siebert, Gerhard A., Chang, Ping, Whitehouse, Michael W., Fletcher, Linda and Crawford, Darrell H. G. (2011). Effect of adjuvant-induced systemic inflammation in rats on hepatic disposition kinetics of taurocholate. American Journal of Physiology-gastrointestinal And Liver Physiology, 300 (1), G130-G136. doi: 10.1152/ajpgi.00162.2010
Douglas, Alexandra, Altukroni, Mahdi, Udy, Andrew A., Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Lipman, Jeffrey and Roberts, Jason A. (2011). The pharmacokinetics of cefazolin in patients undergoing elective and semi-elective abdominal aortic aneurysm open repair surgery. BMC Anesthesiology, 11 (1) 5, 5.1-5.5. doi: 10.1186/1471-2253-11-5
Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2011). Detection of gabapentin-lactose Maillard reaction product (Schiff's Base): Application to solid dosage form preformulation. Part 2. Bestimmung der Maillard-Reaktionsprodukte (Schiff-Base) von Gabapentin und Lactose: Anwendung auf die Vorformulierung einer. pharmind: Die Pharmazeutische Industrie, 73 (2), 376-382.
Geusens, Barbara, Van Gele, Mireille, Braat, Sien, De Smedt, Stefaan C., Stuart, Marc C. A., Prow, Tarl W., Sanchez, Washington, Roberts, Michael S., Sanders, Niek N. and Lambert, Jo (2010). Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in the viable epidermis of ex vivo human skin. Advanced Functional Materials, 20 (23), 4077-4090. doi: 10.1002/adfm.201000484
Green, Bruce, Chandler, Stephen, MacDonald, Garth, Elliott, Geraldine and Roberts, Michael S. (2010). Quantifying pain relief following administration of a novel formulation of paracetamol (Acetaminophen). Journal of Clinical Pharmacology, 50 (12), 1406-1413. doi: 10.1177/0091270009359181
Roberts, MS (2010). Drug structure-transport relationships. Journal of Pharmacokinetics And Pharmacodynamics, 37 (6), 541-573. doi: 10.1007/s10928-010-9174-0
Liu, Xin, Zou, Yuhong, Khlentzos, Alexander M., Yang, Yan, Nikolovski, Julijana, Weiss, Michael and Roberts, Michael S. (2010). Nitric oxide induced sinusoidal relaxation after a propranolol priming dose in the perfused rat liver reduces propranolol availability on subsequent dosing. Clinical and Experimental Pharmacology and Physiology, 37 (10), 1028-1033. doi: 10.1111/j.1440-1681.2010.05434.x
Popov, Alexey P., Zvyagin, Andrei V,, Lademann, Juergen, Roberts, Michael S., Sanchez, Washington, Priezzhev, Alexander V. and Myllyla, Risto (2010). Designing inorganic light-protective skin nanotechnology products. Journal of Biomedical Nanotechnology, 6 (5), 432-451. doi: 10.1166/jbn.2010.1144
Perumal, Omathanu, Michniak-Kohn, Bozena, Touitou, Elka and Roberts, Michael S. (2010). A special issue on skin nanotechnology. Journal of Biomedical Nanotechnology, 6 (5), 405-407. doi: 10.1166/jbn.2010.1142
Robertson, Thomas A., Sanchez, Washington Y. and Roberts, Michael S. (2010). Are commercially available nanoparticles safe when applied to the skin?. Journal of Biomedical Nanotechnology, 6 (5), 452-468. doi: 10.1166/jbn.2010.1145
Roberts, Jason A., Ulldemolins, Marta, Roberts, Michael S., McWhinney, Brett, Ungerer, Jacobus, Paterson, David L. and Lipman, Jeffrey (2010). Therapeutic drug monitoring of beta-lactams in critically ill patients: Proof of concept. International Journal of Antimicrobial Agents, 36 (4), 332-339. doi: 10.1016/j.ijantimicag.2010.06.008
Weiss, Michael, Li, Peng and Roberts, Michael S. (2010). An improved nonlinear model describing the hepatic pharmacokinetics of digoxin: Evidence for two functionally different uptake systems and saturable binding. Pharmaceutical Research, 27 (9), 1999-2007. doi: 10.1007/s11095-010-0204-9
Prow, Tarl W., Chen, Xianfeng, Prow, Natalie A., Fernando, Germain J. P., Tan, Cindy S. E., Raphael, Anthony P., Chang, David, Ruutu, Merja P., Jenkins, Derek W. K., Pyke, Alyssa, Crichton, Michael L., Raphaelli, Kristin, Goh, Lucas Y. H., Frazer, Ian H., Roberts, Michael S., Gardner, Joy, Khromykh, Alexander A., Suhrbier, Andreas, Hall, Roy A. and Kendall, Mark A. F. (2010). Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice. Small, 6 (16), 1776-1784. doi: 10.1002/smll.201000331
Park, Sunwoo, Kim, Sean H. J., Ropella, Glen E. P., Roberts, Michael S. and Hunt, C. Anthony (2010). Tracing multiscale mechanisms of drug disposition in normal and diseased livers. Journal of Pharmacology and Experimental Therapeutics, 334 (1), 124-136. doi: 10.1124/jpet.110.168526
Sanchez, Washington Y., Prow, Tarl W., Sanchez, Washington H., Grice, Jeffrey E. and Roberts, Michael S. (2010). Analysis of the metabolic deterioration of ex vivo skin from ischemic necrosis through the imaging of intracellular NAD(P)H by multiphoton tomography and fluorescence lifetime imaging microscopy. Journal of Biomedical Optics, 15 (4) 046008, 046008-1-046008-11. doi: 10.1117/1.3466580
Grice, Jeffrey E., Cross, Sheree E., Brownlie, Craig and Roberts, Michael S. (2010). The application of molecular structural predictors of intestinal absorption to screening of compounds for transdermal penetration. Journal of Pharmacy and Pharmacology, 62 (6), 750-755. doi: 10.1211/jpp.62.06.0011
Hickman, Peter E., Potter, Julia M., Aroney, Con, Koerbin, Gus, Southcott, Emma, Wu, Alan H. B. and Roberts, Michael S. (2010). Cardiac troponin may be released by ischemia alone, without necrosis. Clinica Chimica Acta, 411 (5-6), 318-323. doi: 10.1016/j.cca.2009.12.009
Gawarammana, Indika Bandara, Roberts, Darren M., Mohamed, Fahim, Roberts, Michael S., Medley, Gregory, Jayamanne, Shaluka and Dawson, Andrew (2010). Acute human self-poisoning with bispyribac-containing herbicide Nominee (R): a prospective observational study. Clinical Toxicology, 48 (3), 198-202. doi: 10.3109/15563651003660000
He, S., Liu, X., Yang, Y., Huang, W., Xu, S., Yang, S., Zhang, X. and Roberts, M. S. (2010). Mechanisms of transforming growth factor beta(1)/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts. British Journal of Dermatology, 162 (3), 538-546. doi: 10.1111/j.1365-2133.2009.09511.x
Liu, Xin, Yang, Yan, Zhang, Xiaoxiang, Xu, Shengxin, He, Shufang, Huang, Weijuan and Roberts, Michael S. (2010). Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2. Journal of Gastroenterology and Hepatology, 25 (2), 420-426. doi: 10.1111/j.1440-1746.2009.05981.x
Grice, Jeffrey E., Ciotti, Susan, Weiner, Norman, Lockwood, Peter, Cross, Sheree E. and Roberts, Michael S. (2010). Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro. Journal of Pharmaceutical Sciences, 99 (2), 712-718. doi: 10.1002/jps.21856
Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010). First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 (2), 156-163. doi: 10.1016/j.ijantimicag.2009.10.008
Zou, Yu-Hong, Liu, Xin, Khlentzos, Alexander M., Asadian, Peyman, Li, Peng, Thorling, Camilla A., Robertson, Thomas A., Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2010). Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. Drug Metabolism and Pharmacokinetics, 25 (5), 442-449. doi: 10.2133/dmpk.DMPK-10-RG-031
Grice, J. E. and Roberts, M. S. (2010). Skin abrasion: Transdermal delivery, cosmetic and immunological applications. Transdermal, 2 (1), 11-16.
Fernando, Germain J. P., Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Fairmaid, Emily J., Roberts, Michael S., Frazer, Ian H., Brown, Lorena E. and Kendall, Mark A. F. (2010). Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model. PLoS One, 5 (4) e10266, e10266.1-e10266.11. doi: 10.1371/journal.pone.0010266
Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2009). Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets. European Journal of Pharmaceutics and Biopharmaceutics, 73 (3), 404-413. doi: 10.1016/j.ejpb.2009.06.012
Mutalik, S., Hewavitharana, A., Shaw, P. N., Anissimov, Y. G., Roberts, M. S. and Parekh, H. S. (2009). Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877 (29), 3556-3562. doi: 10.1016/j.jchromb.2009.08.039
Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Jenkins, Derek W.K., Roberts, Michael S., Frazer, Ian H., Fernando, Germain J.P. and Kendall, Mark A.F. (2009). Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin. Journal of Controlled Release, 139 (3), 212-220. doi: 10.1016/j.jconrel.2009.06.029
Dalley, A.J., Lipman, J., Deans, R., Venkatesh, B., Rudd, M., Roberts, M.S. and Cross, S.E. (2009). Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial Agents and Chemotherapy, 53 (1), 210-215. doi: 10.1128/AAC.00718-08
Xia, C.H., Sun, J.G., Wang, G.J., Shang, L.L., Zhang, X.X., Zhang, R., Peng, Y., Wang, X.J., Hao, H.P., Xie, L. and Roberts, M.S. (2009). Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats. Planta Medica: natural products and medicinal plant research, 76 (3), 245-250. doi: 10.1055/s-0029-1186082
Fanning, Kent J., Anissimov, Yuri G. and Roberts, Michael S. (2009). Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver. Journal of Pharmaceutical Sciences, 98 (8), 2807-2821. doi: 10.1002/jps.21631
Zhang, Qian, Grice, Jeffrey E., Li, Peng, Jepps, Owen G., Wang, Guang-Ji and Roberts, Michael S. (2009). Skin solubility determines maximum transepidermal flux for similar size molecules. Pharmaceutical Research, 26 (8), 1974-1985. doi: 10.1007/s11095-009-9912-4
Li, Peng, Wang, Guang-Ji, Robertson, Thomas A. and Roberts, Michael S. (2009). Liver transporters in hepatic drug disposition: An update. Current Drug Metabolism, 10 (5), 482-498. doi: 10.2174/138920009788898037
Yan, J., Gong, Y. W., She, Y. M., Wang, G. Q., Roberts, M. S. and Burczynski, F. J. (2009). Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity. Journal of Lipid Research, 50 (12), 2445-2454. doi: 10.1194/jlr.M900177-JLR200
Liu, X., Wang, J. Y., Khlentzos, A. M., Fontaine, F., Nikolovski, J., Goh, L.- A. and Roberts, M. S. (2009). Influence of perfusate composition on drug disposition in the in-situ perfused rat lung. International Journal of Pharmaceutics, 382 (1-2), 192-197. doi: 10.1016/j.ijpharm.2009.08.028
Mohamed, Fahim, Gawarammana, Indika, Robertson, Thomas A., Roberts, Michael S., Palangasinghem, Chathura, Zawahir, Shukry, Jayamanne, Shaluka, Kandasamy, Jaganathan, Eddleston, Michael, Buckley, Nick A., Dawson, Andrew H and Roberts, Darren M. (2009). Acute human self-poisoning with imidacloprid compound: A neonicotinoid insecticide. PLoS One, 4 (4) e5127, 1-5. doi: 10.1371/journal.pone.0005127
Kruger, Peter S., Freir, Noelle M., Venkatesh, Bala, Robertson, Thomas A, Roberts, Michael S. and Jones, Mark (2009). A preliminary study of atorvastatin plasma concentrations in critically ill patients with sepsis. Intensive Care Medicine, 35 (4), 717-721. doi: 10.1007/s00134-008-1358-3
Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Piperacillin penetration into tissue of critically ill patients with sepsis - Bolus versus continuous administration?. Critical Care Medicine, 37 (3), 926-933. doi: 10.1097/CCM.0b013e3181968e44
Zhang, Qian, Grice, Jeffrey E., Wang, Guangji and Roberts, Michael S. (2009). Cutaneous metabolism in transdermal drug delivery. Current Drug Metabolism, 10 (3), 227-235. doi: 10.2174/138920009787846350
Anissimov, Y. and Roberts, M. S. (2009). Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics. Journal of Pharmaceutical Sciences, 98 (2), 772-781. doi: 10.1002/jps.21461
Kaur, S., Mitchell, G., Vitetta, L. and Roberts, M.S. (2009). Interventions that can reduce inappropriate prescribing in the elderly: A systematic review. Drugs & Ageing, 26 (12), 1013-1028. doi: 10.2165/11318890-000000000-00000
Park, Sunwoo, Ropella, Glen E. P., Kim, Sean H. J., Roberts, Michael S. and Hunt, C. Anthony (2009). Computational strategies unravel and trace how liver disease changes hepatic drug disposition. Journal of Pharmacology and Experimental Therapeutics, 328 (1), 294-305. doi: 10.1124/jpet.108.142497
Monajjemzadeh, F., Hassanzadeh, D., Valizadeh, H, Siahi-Shadbad, M. R., Mojarrad, J. S., Robertson, T. and Roberts, MS (2009). Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies. AAPS PHARMSCITECH, 10 (2), 649-659. doi: 10.1208/s12249-009-9248-8
Dalley, Andrew J., Deans, Renae, Lipman, Jeffrey, Venkatesh, Bala, Rudd, Michael, Roberts, Michael S. and Cross, Sheree E. (2009). Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury. Antimicrobial Agents and Chemotherapy, 53 (12), 5303-5305. doi: 10.1128/AAC.01600-08
Cohen, Jeremy, Deans, Renae, Dalley, Andrew, Lipman, Jeff, Roberts, Michael S. and Venkatesh, Bala (2009). Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation. Critical Care, 13 (6), xx-xx. doi: 10.1186/cc8184
Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 (1), 142-150. doi: 10.1093/jac/dkp139
Roberts, Michael S., Roberts, Matthew J., Robertson, Thomas A., Sanchez, Washington, Thorling, Camilla, Zou, Yuhong, Zhao, Xin, Becker, Wolfgang and Zvyagin, Andrei V. (2008). In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver. Journal of Biophotonics, 1 (6), 478-493. doi: 10.1002/jbio.200810058
Xai, Chun-hua, Sun, Jian-guo, Hao, Hai-ping, Wang, Guang-ji, Yan, Bei, Gu, Sheng-hua, Zheng, Chao-nan, Shang, Li-li and Roberts, Michael S. (2008). Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat. Planta Medica, 74 (15), 1832-1836. doi: 10.1055/s-0028-1088339
Roberts, Michael S. (2008). Common skin conditions and disorders. Drug Discovery Today: Disease Mechanisms, 5 (2), 125-126. doi: 10.1016/j.ddmec.2008.09.008
Weiss, Michael, Hung, Daniel Y., Poenicke, Klaus and Roberts, Michael S. (2008). Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin. European Journal of Pharmaceutical Sciences, 34 (4-5), 345-350. doi: 10.1016/j.ejps.2008.05.007
Cross, Sheree E. and Roberts, Michael S. (2008). Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes. Journal of Pharmaceutical Sciences, 97 (8), 3442-3450. doi: 10.1002/jps.21253
Nohynek, G. J., Dufour, E. K. and Roberts, M. S. (2008). Nanotechnology, cosmetics and the skin: Is there a health risk?. Skin Pharmacology & Physiology, 21 (3), 136-149. doi: 10.1159/000131078
Yan, Li, Ropella, Glen E. P., Park, Sunwoo, Roberts, Michael S. and Hunt, C. Anthony (2008). Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver. Pharmaceutical Research, 25 (5), 1023-1036. doi: 10.1007/s11095-007-9494-y
Roberts, Michael S. (2008). Skin diseases. Drug Discovery Today: Disease Mechanisms, 5 (1), e1-e2. doi: 10.1016/j.ddmec.2008.09.007
Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Cross, Sheree E. and Lipman, Jeffrey (2008). A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis. International Journal of Antimicrobial Agents, 31 (3), 240-244. doi: 10.1016/j.ijantimicag.2007.09.013
Winckle, G., Anissimov, Y. G., Cross, S. E., Wise, G. and Roberts, M. S. (2008). An integrated pharmacokinetic and imaging evaluation of vehicle effects on solute human epidermal flux and, retention characteristics. Pharmaceutical Research, 25 (1), 158-166. doi: 10.1007/s11095-007-9416-z
Alenius, H., Roberts, D. W., Tokura, Y., Lauerma, A., Patlewicz, G. and Roberts, M. S. (2008). Skin, drug and chemical reactions. Drug Discovery Today: Disease Mechanisms, 5 (2), e211-e220. doi: 10.1016/j.ddmec.2008.06.001
Li, P., Wang, G-J., Li, J., Liu, X., Khlentzos, A. and Roberts, M. S. (2008). The prediction of the hepatic clearance of Tanshinone IIA in a rat liver subcellular fractions: accuracy improvement. Current Drug Metabolism, 9 (1), 39-45. doi: 10.2174/138920008783331103
Cross, S. E., Russel, M., Southwell, I. and Roberts, M. S. (2008). Human skin penetration of the major components of Australian tea tree oil applied in its pure form and as a 20% solution in vitro. European Journal of Pharmaceutics And Biopharmaceutics, 69 (1), 214-222. doi: 10.1016/j.ejpb.2007.10.002
Rawlings, A. V., Matts, P. J., Anderson, C. D. and Roberts, M. S. (2008). Skin biology, xerosis, barrier repair and measurement. Drug Discovery Today: Disease Mechanisms, 5 (2), e127-e136. doi: 10.1016/j.ddmec.2008.03.001
Zou, Y., Yang, Y., Li, J., Wu, Q., Li, W-P, Lu, J-T and Roberts, M.S. (2008). Potential therapeutic effects of a traditional Chinese formulation, BJ-Jn on liver fibrosis induced by carbon tetrachloride in rats. Journal Of Ethnopharmacology, 120 (3), 452-457. doi: 10.1016/j.jep.2008.09.023
Ahmed, A. H., Soyer, H. P., Saunders, N., Boukamp, P. and Roberts, M. S. (2008). Non-melanoma skin cancers. Drug Discovery Today: Disease Mechanisms, 5 (1), e55-e62. doi: 10.1016/j.ddmec.2008.05.007
Zvyagin, Andrei V., Zhao, Xin, Gierden, Audrey, Sanchez, Washington, Ross, Justin A. and Roberts, Michael. S. (2008). Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo. Journal of Biomedical Optics, 13 (6) 064031, 064031-1-064031-9. doi: 10.1117/1.3041492
Dalley, Andrew J., Lipman, Jeffrey, Venkatesh, Bala, Rudds, Michael, Roberts, Michael S. and Cross, Sheree E. (2007). Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement. Journal of Antimicrobial Chemotherapy, 60 (1), 166-169. doi: 10.1093/jac/dkm128
Arab, H. A., Cheung, K., Hickman, P. E., Potter, J. M., Kadkhodaee, M. and Roberts, M. S. (2007). Effects of hypoxia/reperfusion injury on drug disposition in the rat isolated perfused liver. Clinical And Experimental Pharmacology And Physiology, 34 (4), 332-338. doi: 10.1111/j.1440-1681.2007.04550.x
Nohynek, Gerhard J., Lademann, Jürgen, Ribaud, Christele and Roberts, Michael S. (2007). Grey goo on the skin? Nanotechnology, cosmetic and sunscreen safety. Critical Reviews In Toxicology, 37 (3), 251-277. doi: 10.1080/10408440601177780
Atrux-Tallau, N., Pirot, F., Falson, F., Roberts, M. S. and Maibach, H. I. (2007). Qualitative and quantitative comparison of heat separated epidermis and dermatomed skin in percutaneous absorption studies. Archives of Dermatological Research, 299 (10), 507-511. doi: 10.1007/s00403-007-0789-y
Wang, G. Q., Shen, H., Rajaraman, G., Roberts, M. S., Gong, Y. W., Jiang, P. and Burczynski, F. (2007). Expression and antioxidant function of liver fatty acid binding protein in normal and bile-duct ligated rats. European Journal of Pharmacology, 560 (1), 61-68. doi: 10.1016/j.ejphar.2007.01.015
Fanning, Kent John and Roberts, Michael S. (2007). Characterization of the physiological spaces and distribution of tolbutamide in the perfused rat pancreas. Pharmaceutical Research, 24 (3), 512-520. doi: 10.1007/s11095-006-9167-2
King, M. A. and Roberts, M. S. (2007). The influence of the Pharmaceutical Benefits Scheme (PBS) on inappropriate prescribing in Australian nursing homes. Pharmacy World & Science, 29 (1), 39-42. doi: 10.1007/s11096-005-5618-9
Mo, Y.-K., Kankavi, O., Masci, P. P., Mellick, G. D., Whitehouse, M. W., Boyle, G. M., Parsons, P. G., Roberts, M. S. and Cross, S. E. (2007). Surfactant protein expression in human skin: Evidence and implications. Journal of Investigative Dermatology, 127 (2), 381-386. doi: 10.1038/sj.jid.5700561
Cross, S. E., Innes, B., Roberts, M. S., Tsuzuki, T., Robertson, T. A. and McCormick, P. (2007). Human skin penetration of sunscreen nanoparticles: In-vitro assessment of a novel micronized zinc oxide formulation. Skin Pharmacology And Physiology, 20 (3), 148-154. doi: 10.1159/000098701
Hunt, C. Anthony, Ropella, Glen E. P., Yan, Li, Hung, Daniel Y. and Roberts, Michael S. (2006). Physiologically based synthetic models of hepatic disposition. Journal of Pharmacokinetics and Pharmacodynamics, 33 (6), 737-772. doi: 10.1007/s10928-006-9031-3
Mollee, TR, Anissimov, YG and Roberts, MS (2006). Periodic electric field enhanced transport through membranes. Journal of Membrane Science, 278 (1-2), 290-300. doi: 10.1016/j.memsci.2004.10.049
Magnusson, BM, Cross, SE, Winckle, G and Roberts, MS (2006). Percutaneous absorption of steroids: Determination of in vitro permeability and tissue reservoir characteristics in human skin layers. Skin Pharmacology And Physiology, 19 (6), 336-342. doi: 10.1159/000095254
Hung, Daniel Y., Siebert, Gerhard A., Chang, Ping, Whitehouse, Michael W., Fletcher, Linda, Crawford, Darrell H. G. and Roberts, Michael S. (2006). Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation. American Journal of Physiology-gastrointestinal And Liver Physiology, 290 (2), G343-G351. doi: 10.1152/ajpgi.00155.2005
Stokes, J. A. and Roberts, M. S. (2006). Complementary medicines in Australian veterans. Reply. Journal of Pharmacy Practice and Research, 36 (1), 80-80.
Sorensen, L, Stokes, JA, Purdie, DM, Woodward, M and Roberts, MS (2006). Medication management at home: medication risk factor prevalence and inter-relationships. Journal of Clinical Pharmacy And Therapeutics, 31 (5), 485-491. doi: 10.1111/j.1365-2710.2006.00768.x
Blazkiewicz, P., Blazkiewicz, K., Verhaege, A., Anissimov, Y. G., Roberts, M. S. and Zvyagin, A. V. (2006). Dialysis-assisted fiber optic spectroscopy for in situ biomedical sensing. Journal Of Biomedical Optics, 11 (1) 014033, 014033.1-014033.7. doi: 10.1117/1.2166086