The aim of the Kumari Group is to identify immuno-modulatory signals and understand cellular and molecular mechanisms controlling inflammatory diseases like psoriasis, and skin cancer. Using multi-dimensional and cutting-edge methodologies in Immunology, Biochemistry, Cell- and Molecular Biology, and in vivo, in vitro and 3D culture systems, we aim to achieve the overarching goal of bringing fundamental scientific discoveries in skin immunity at the forefront to develop better therapeutic strategies.

Our research focuses on:

  • Identifying new immune regulatory mechanisms and signals involved in skin inflammation.
  • Elucidating cellular and molecular signaling mechanisms regulating skin immune homeostasis.
  • Investigating tumor-intrinsic mechanisms and innate immunity to develop novel therapeutics and immunotherapy for skin cancer (melanoma and non-melanoma).