• Understanding the molecular control of dendritic cell function in tolerance
  • Pathogenesis of inflammatory bowel disease, psoriasis, uveitis and arthritis in a mouse model of spondyloarthropathy: microbiota and the interaction with host immunity
  • Rheumatoid arthritis antigen-specific therapy: nanoparticle development and immune responses. Animal models, clinical trials
  • Biomarkers of risk in individuals at risk of rheumatoid arthritis
  • Antigen-specific T cells in Rheumatoid Arthritis: MHC-peptide interactions with T cells, synovial tissue T cell populations
  • Type 1 (Juvenile) Diabetes novel treatments: preclinical development
  • Type 1 diabetes biomarkers: human longitudinal study and association with remission
  • Antigen-specific T cells in ANCA vasculitis

Student projects

  • Identification of individuals with or at risk of Type 1 Diabetes suitable for antigen-specific tolerising immunotherapy
  • Interaction of the gut microbiome with the immune response in the predisposition to Spondyloarthritis
  • The antigen-specific immune response in ANCA-associated vasculitis
  • Immunogenic peptide epitopes in Graves' disease
  • Unique T cell receptors (TCR) in autoimmune disease: biomarkers and therapeutic targets
  • Factors influencing clinical remission in type 1 diabetes
  • Nanoparticle delivery systems for antigen-specific immunotherapy in type 1 diabetes