Associate Professor Timothy Wells

Wells, Timothy J. and Henderson, Ian R. (2013). Type 1 and 5 secretion systems and associated toxins. Escherichia coli: pathotypes and principles of pathogenesis. (pp. 499-532) edited by Michael S. Donnenberg. Cambridge, MA, United States: Academic Press. doi: 10.1016/B978-0-12-397048-0.00016-4

Johnson, Timothy J., Miller, Elizabeth A., Flores-Figueroa, Cristian, Munoz-Aguayo, Jeannette, Amato, Heather, Salinas, Liseth, Trueba, Gabriel and Graham, Jay P. (2025). Extensive Overlap in Avian and Extraintestinal Pathogenic Escherichia coli Strains Between Backyard Poultry, Humans, and Dogs in Ecuador. Avian Diseases, 69 (3), 252-264.

Panthi, Vijay Kumar, Fairfull-Smith, Kathryn E., Wells, Timothy J., Wang, Tony and Islam, Nazrul (2025). Ceftriaxone-Loaded Liposomal Nanoparticles for Pulmonary Delivery Against Lower Respiratory Tract Infections: Development and Characterization. Pharmaceuticals, 18 (3) 414, 414. doi: 10.3390/ph18030414

Hickson, Sarah M., Ledger, Emma L. and Wells, Timothy J. (2025). Emerging antimicrobial therapies for Gram-negative infections in human clinical use. npj Antimicrobials and Resistance, 3 (1) 16, 16. doi: 10.1038/s44259-025-00087-2

Manjankattil, Shijinaraj, Dewi, Grace, Peichel, Claire, Creek, Medora, Bina, Peter, Johnson, Timothy J., Cox, Ryan, Noll, Sally and Johny, Anup Kollanoor (2025). Effect of pimenta essential oil and peracetic acid as pre-grind dip treatments on emerging Salmonella, spoilage bacteria, and quality attributes of ground turkey during chilled storage. Poultry Science, 104 (4) 104829, 104829. doi: 10.1016/j.psj.2025.104829

Suraweera, Ruwani K., Spann, Kirsten M., Wells, Timothy J. and Islam, Nazrul (2025). Inhaled combined antibacterials against biofilm-forming antibiotic-resistant bacteria for the management of pulmonary bacterial infections. Journal of Drug Delivery Science and Technology, 104 106555, 106555. doi: 10.1016/j.jddst.2024.106555

Matheus, Gabriela Gonzalez, Chamoun, Michelle N., Khosrotehrani, Kiarash, Sivakumaran, Yogeesan and Wells, Timothy J. (2025). Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers. Burns and Trauma, 13 tkae083, tkae083. doi: 10.1093/burnst/tkae083

Pina-Iturbe, Alejandro, Fredes-Garcia, Diego, Garcia, Patricia, Porte, Lorena, Johnson, Timothy J., Singer, Randall S., Toro, Magaly, Munita, Jose M. and Moreno-Switt, Andrea I. (2025). Salmonella enterica Serovar Abony Outbreak Caused by Clone of Reference Strain WDCM 00029, Chile, 2024. Emerging Infectious Diseases, 31 (1), 186-189. doi: 10.3201/eid3101.241012

Suraweera, Ruwani K., Spann, Kirsten M., Izake, Emad L., Wells, Timothy J., Wang, Xiaodong and Islam, Nazrul (2024). Development and characterization of spray-dried combined levofloxacin–ambroxol dry powder inhaler formulation. Pharmaceutics, 16 (12) 1506, 1506. doi: 10.3390/pharmaceutics16121506

McCulloch, Timothy R., Rossi, Gustavo R., Alim, Louisa, Lam, Pui Yeng, Wong, Joshua K. M., Coleborn, Elaina, Kumari, Snehlata, Keane, Colm, Kueh, Andrew J., Herold, Marco J., Wilhelm, Christoph, Knolle, Percy A., Kane, Lawrence, Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2024). Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation. Nature Communications, 15 (1) 9871, 1-16. doi: 10.1038/s41467-024-54232-y

Hashish, Amro, Johnson, Timothy J., Ghanem, Mostafa, Sato, Yuko, Macedo, Nubia R., LeCount, Karen J. and El-Gazzar, Mohamed (2024). Complete genome sequences of eight Pasteurella multocida isolates representing all lipopolysaccharide outer core loci. Microbiology Resource Announcements, 13 (11). doi: 10.1128/mra.00604-24

Da Costa, Rochelle M., Rooke, Jessica L., Wells, Timothy J., Cunningham, Adam F. and Henderson, Ian R. (2024). Type 5 secretion system antigens as vaccines against Gram-negative bacterial infections. npj Vaccines, 9 (1) 159, 159. doi: 10.1038/s41541-024-00953-6

Pham, Amy, Tan, Kellynn K. Y., Ledger, Emma L., Smith, Daniel J., Reid, David W., Burr, Lucy, Chambers, Daniel C. and Wells, Timothy J. (2024). Cloaking antibodies are prevalent in Burkholderia cepacia complex infection and their removal restores serum killing. Frontiers in Cellular and Infection Microbiology, 14 1426773, 1426773. doi: 10.3389/fcimb.2024.1426773

Wells, Timothy J., Esposito, Tyron, Henderson, Ian R. and Labzin, Larisa I. (2024). Mechanisms of antibody-dependent enhancement of infectious disease. Nature Reviews Immunology, 25 (1) e33073, 6-21. doi: 10.1038/s41577-024-01067-9

McCulloch, Timothy R., Rossi, Gustavo R., Miranda‐Hernandez, Socorro, Valencia‐Hernandez, Ana Maria, Alim, Louisa, Belle, Clemence J., Krause, Andrew, Zacchi, Lucia F., Lam, Pui Yeng, Nakamura, Kyohei, Kupz, Andreas, Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2024). The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy. Immunology and Cell Biology, 102 (8), 721-733. doi: 10.1111/imcb.12794

Aziz, Maliha, Davis, Gregg S., Park, Daniel E., Idris, Azza H., Sariya, Sanjeev, Wang, Yashan, Zerbonne, Sarah, Nordstrom, Lora, Weaver, Brett, Statham, Sally, Johnson, Timothy J., Campos, Joseph, Castro-Nallar, Eduardo, Crandall, Keith A., Wu, Zhenke, Liu, Cindy M., DeBiasi, Roberta L. and Price, Lance B. (2024). Pediatric urinary tract infections caused by poultry-associated Escherichia coli. Microbiology Spectrum, 12 (7). doi: 10.1128/spectrum.03415-23

Singer, Randall S. and Johnson, Timothy J. (2024). Assessing the Risk of Antimicrobial Resistant Enterococcal Infections in Humans Due to Bacitracin Usage in Poultry. Journal of Food Protection, 87 (5) 100267, 100267. doi: 10.1016/j.jfp.2024.100267

Ledger, Emma L., Smith, Daniel J., Teh, Jing Jie, Wood, Michelle E., Whibley, Page E., Morrison, Mark, Goldberg, Joanna B., Reid, David W. and Wells, Timothy J. (2024). Impact of CFTR modulation on Pseudomonas aeruginosa infection in people with cystic fibrosis. The Journal of Infectious Diseases, 230 (3), e536-e547. doi: 10.1093/infdis/jiae051

Hickson, Sarah M., Hoehensteiger, Johannes K., Mayer-Coverdale, Johanna, Torres, Von Vergel L., Feng, Wenkang, Monteith, Joshua N., Henderson, Ian R., McCarthy, Kate L. and Wells, Timothy J. (2024). Antibody-mediated serum resistance protects Pseudomonas aeruginosa during bloodstream infections. The Journal of Infectious Diseases, 230 (2), e221-e229. doi: 10.1093/infdis/jiad457

Pham, Amy, Volmer, James G., Chambers, Daniel C., Smith, Daniel J., Reid, David W., Burr, Lucy and Wells, Timothy J. (2023). Genomic analyses of Burkholderia respiratory isolates indicates two evolutionarily distinct B. anthina clades. Frontiers in Microbiology, 14 1274280, 1-14. doi: 10.3389/fmicb.2023.1274280

Nadimpalli, Maya L., Stegger, Marc, Viau, Roberto, Yith, Vuthy, de Lauzanne, Agathe, Sem, Nita, Borand, Laurence, Huynh, Bich-tram, Brisse, Sylvain, Passet, Virginie, Overballe-Petersen, Soren, Aziz, Maliha, Gouali, Malika, Jacobs, Jan, Phe, Thong, Hungate, Bruce A., Leshyk, Victor O., Pickering, Amy J., Gravey, Francois, Liu, Cindy M., Johnson, Timothy J., Le Hello, Simon and Price, Lance B. (2023). Plugging the leaks: antibiotic resistance at human-animal interfaces in low-resource settings. Frontiers in Ecology and the Environment, 21 (9), 428-434. doi: 10.1002/fee.2639

Amato, Heather K., Loayza, Fernanda, Salinas, Liseth, Paredes, Diana, Garcia, Daniela, Sarzosa, Soledad, Saraiva-Garcia, Carlos, Johnson, Timothy J., Pickering, Amy J., Riley, Lee W., Trueba, Gabriel and Graham, Jay P. (2023). Leveraging the COVID-19 pandemic as a natural experiment to assess changes in antibiotic use and antibiotic-resistant E. coli carriage in semi-rural Ecuador. Scientific Reports, 13 (1) 14854. doi: 10.1038/s41598-023-39532-5

Johnson, Abigail, Miller, Elizabeth A., Weber, Bonnie, Figueroa, Cristian Flores, Aguayo, Jeannette Munoz, Johny, Anup Kollanoor, Noll, Sally, Brannon, Jeanine, Kozlowicz, Briana and Johnson, Timothy J. (2023). Evidence of host specificity in Lactobacillus johnsonii genomes and its influence on probiotic potential in poultry. Poultry Science, 102 (9) 102858, 1-13. doi: 10.1016/j.psj.2023.102858

Chaney, Evan, Miller, Elizabeth A., Firman, Jeffrey, Binnebose, Andrea, Kuttappan, Vivek and Johnson, Timothy J. (2023). Effects of a postbiotic, with and without a saponin-based product, on turkey performance. Poultry Science, 102 (5) 102607, 1-5. doi: 10.1016/j.psj.2023.102607

Hashish, Amro, Johnson, Timothy J., Chundru, Dhiraj, Williams, Michele L., Sato, Yuko, Macedo, Nubia R., Clessin, Augustin, Gantelet, Hubert, Bost, Caroline, Tornos, Jeremy, Gamble, Amandine, LeCount, Karen J., Ghanem, Mostafa, Boulinier, Thierry and El-Gazzar, Mohamed (2023). Complete Genome Sequences of Two Pasteurella multocida Isolates from Seabirds. Microbiology Resource Announcements, 12 (4) e01365-22. doi: 10.1128/mra.01365-22

Bueno, Irene, Ricke, Isabel, Hwang, Haejin, Smith, Emily, Nault, Andre, Johnson, Timothy J. and Singer, Randall S. (2023). Efficacy of antibiotic and non-antibiotic interventions in preventing and treating necrotic enteritis in broiler chickens: a systematic review. Avian Diseases, 67 (1), 20-32. doi: 10.1637/aviandiseases-D-22-00069

Shojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438

Glaser, D. R., Henderson, R. D., Werkema, D. D., Johnson, T. J. and Versteeg, R. J. (2022). Estimating biofuel contaminant concentration from 4D ERT with mixing models. Journal of Contaminant Hydrology, 248 104027, 104027. doi: 10.1016/j.jconhyd.2022.104027

McCulloch, Timothy R., Rossi, Gustavo R., Schreuder, Jaring, Belz, Gabrielle T., Wells, Timothy J. and Souza‐Fonseca‐Guimaraes, Fernando (2022). CIS and TGF ‐β regulatory pathways influence immunity to bacterial infection. Immunology, 167 (1), 54-63. doi: 10.1111/imm.13516

Maurer, John J., Simoes-Barbosa, Augusto, Johnson, Timothy J. and Conway, Tyrrell (2022). Editorial: The Interplay of Host-Microbiome-Pathogen on Infectious Diseases. Frontiers in Microbiology, 13 924807. doi: 10.3389/fmicb.2022.924807

Webb, Kasey A., Olagoke, Olusola, Baird, Timothy, Neill, Jane, Pham, Amy, Wells, Timothy J., Ramsay, Kay A., Bell, Scott C., Sarovich, Derek S. and Price, Erin P. (2022). Genomic diversity and antimicrobial resistance of Prevotella species isolated from chronic lung disease airways. Microbial Genomics, 8 (2) 000754. doi: 10.1099/mgen.0.000754

Tran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-Bolívar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166

Manjankattil, Shijinaraj, Nair, Divek V. T., Peichel, Claire, Noll, Sally, Johnson, Timothy J., Cox, Ryan B., Donoghue, Annie M. and Johny, Anup Kollanoor (2021). Effect of caprylic acid alone or in combination with peracetic acid against multidrug-resistant Salmonella Heidelberg on chicken drumsticks in a soft scalding temperature-time setup. Poultry Science, 100 (11) 101421, 101421. doi: 10.1016/j.psj.2021.101421

Divithotawela, Chandima, Pham, Amy, Bell, Peter T., Ledger, Emma L., Tan, Maxine, Yerkovich, Stephanie, Grant, Michelle, Hopkins, Peter M., Wells, Timothy J. and Chambers, Daniel C. (2021). Inferior outcomes in lung transplant recipients with serum Pseudomonas aeruginosa specific cloaking antibodies. The Journal of Heart and Lung Transplantation, 40 (9), 951-959. doi: 10.1016/j.healun.2021.05.016

Pham, Amy, Ledger, Emma L., Coggon, Carrie F., Henderson, Ian R., Reid, David W., Bell, Scott C., Smith, Daniel J. and Wells, Timothy J. (2021). Anti-LPS IgA and IgG can inhibit serum killing of Pseudomonas aeruginosa in patients with cystic fibrosis. Infection and Immunity, 89 (12) e00412-21, e0041221. doi: 10.1128/iai.00412-21

Leite, Fernando L., Winfield, Brittanie, Miller, Elizabeth A., Weber, Bonnie P., Johnson, Timothy J., Sylvia, Fred, Vasquez, Erika, Vannucci, Fabio, Beckler, Dana and Isaacson, Richard E. (2021). Oral vaccination reduces the effects of Lawsonia intracellularis challenge on the swine small and large intestine microbiome. Frontiers in Veterinary Science, 8 692521. doi: 10.3389/fvets.2021.692521

McCulloch, Timothy R., Wells, Timothy J. and Souza-Fonseca-Guimaraes, Fernando (2021). Towards efficient immunotherapy for bacterial infection. Trends in Microbiology, 30 (2), 158-169. doi: 10.1016/j.tim.2021.05.005

Romand, Xavier, Liu, Xiao, Rahman, M. Arifur, Bhuyan, Zaied Ahmed, Douillard, Claire, Arora Kedia, Reena, Stone, Nathan, Roest, Dominique, Chew, Zi Huai, Cameron, Amy J., Rehaume, Linda M., Bozon, Aurélie, Habib, Mohammed, Armitage, Charles W., Nguyen, Minh Vu Chuong, Favier, Bertrand, Beagley, Kenneth, Maurin, Max, Gaudin, Philippe, Thomas, Ranjeny, Wells, Timothy J. and Baillet, Athan (2021). Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG mice. Arthritis and Rheumatology, 73 (7) art.41653, 1200-1210. doi: 10.1002/art.41653

Dewi, Grace, Nair, Divek V. T., Peichel, Claire, Johnson, Timothy J., Noll, Sally and Johny, Anup Kollanoor (2021). Effect of lemongrass essential oil against multidrug-resistant Salmonella Heidelberg and its attachment to chicken skin and meat. Poultry Science, 100 (7) 101116, 101116. doi: 10.1016/j.psj.2021.101116

Wang, Xi, Chaney, W. Evan, Pavlidis, Hilary O., McGinnis, James P., Byrd, J. Allen, Farnell, Yuhua Z., Johnson, Timothy J., McElroy, Audrey P. and Farnell, Morgan B. (2021). Determination of Antimicrobial Resistance Patterns in Salmonella from Commercial Poultry as Influenced by Microbiological Culture and Antimicrobial Susceptibility Testing Methods. Microorganisms, 9 (6) 1319, 1319. doi: 10.3390/microorganisms9061319

Miller, Elizabeth A., Winfield, Brittanie, Weber, Bonnie P., Flores-Figueroa, Cristian, Munoz-Aguayo, Jeannette, Huisinga, Jared and Johnson, Timothy J. (2021). Convergence of the turkey gut microbiota following cohabitation under commercial settings. Journal of Animal Science and Biotechnology, 12 (1) 59. doi: 10.1186/s40104-021-00580-4

Pestana-Oliveira, Nayara, Nahey, David B., Hartson, Rochelle, Weber, Bonnie, Johnson, Timothy J. and Collister, John P. (2021). DOCA-salt hypertension and the role of the OVLT-sympathetic-gut microbiome axis. Clinical and Experimental Pharmacology and Physiology, 48 (4), 490-497. doi: 10.1111/1440-1681.13457

Mulholland, Kelly A., Robinson, Monique G., Keeler, Sharon J., Johnson, Timothy J., Weber, Bonnie W. and Keeler, Calvin L. (2021). Metagenomic Analysis of the Respiratory Microbiome of a Broiler Flock from Hatching to Processing. Microorganisms, 9 (4) 721, 721. doi: 10.3390/microorganisms9040721

Rooke, Jessica L., Icke, Christopher, Wells, Timothy J, Rossiter, Amanda E., Browning, Douglas F., Morris, Faye C., Leo, Jack C., Schütz, Monika S., Autenrieth, Ingo B., Cunningham, Adam F., Linke, Dirk and Henderson, Ian R. (2021). BamA and BamD are essential for the secretion of trimeric autotransporter adhesins. Frontiers in Microbiology, 12 628879, 1-10. doi: 10.3389/fmicb.2021.628879

Salinas, Liseth, Loayza, Fernanda, Cardenas, Paul, Saraiva, Carlos, Johnson, Timothy J., Amato, Heather, Graham, Jay P. and Trueba, Gabriel (2021). Environmental spread of extended spectrum beta-lactamase (ESBL) producing Escherichia coli and ESBL genes among children and domestic animals in Ecuador. Environmental Health Perspectives, 129 (2) 027007, 1-10. doi: 10.1289/EHP7729

Torres, Von Vergel L., Coggon, Carrie F. and Wells, Timothy J. (2021). Antibody-dependent enhancement of bacterial disease: prevalence, mechanisms and treatment. Infection and Immunity, 89 (4) e00054-21, 1-15. doi: 10.1128/IAI.00054-21

Moentadj, Rabia, Wang, Yiwen, Bowerman, Kate, Rehaume, Linda, Nel, Hendrik, O Cuiv, Paraic, Stephens, Juliette, Baharom, Amalina, Maradana, Muralidhara, Lakis, Vanessa, Morrison, Mark, Wells, Timothy, Hugenholtz, Philip, Benham, Helen, Le Cao, Kim-Anh and Thomas, Ranjeny (2021). Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice. Annals of the Rheumatic Diseases, 80 (5) annrheumdis-2020-219009, annrheumdis-2020. doi: 10.1136/annrheumdis-2020-219009

Abundo, Michael E. C., Ngunjiri, John M., Taylor, Kara J. M., Ji, Hana, Ghorbani, Amir, Mahesh, K. C., Weber, Bonnie P., Johnson, Timothy J. and Lee, Chang-Won (2021). Assessment of two DNA extraction kits for profiling poultry respiratory microbiota from multiple sample types. PLoS One, 16 (1) e0241732, 1-19. doi: 10.1371/journal.pone.0241732

Miller, Elizabeth A., Ponder, Julia B., Willette, Michelle, Johnson, Timothy J. and VanderWaal, Kimberly L. (2020). Merging metagenomics and spatial epidemiology to understand the distribution of antimicrobial resistance genes from Enterobacteriaceae in wild owls. Applied and Environmental Microbiology, 86 (20) e00571-20, 1-16. doi: 10.1128/AEM.00571-20

Abundo, Michael Edward C., Ngunjiri, John M., Taylor, Kara J. M., Ji, Hana, Ghorbani, Amir, Mahesh, K. C., Elaish, Mohamed, Jang, Hyesun, Weber, Bonnie, Johnson, Timothy J. and Lee, Chang-Won (2020). Evaluation of Sampling Methods for the Study of Avian Respiratory Microbiota. Avian Diseases, 64 (3), 277-285.

Azam, Mariya, Mohsin, Mashkoor, Johnson, Timothy J., Smith, Emily A., Johnson, Abigail, Umair, Muhammad, Saleemi, Muhammad Kashif and Sajjad-ur-Rahman, (2020). Genomic landscape of multi-drug resistant avian pathogenic Escherichia coli recovered from broilers. Veterinary Microbiology, 247 108766, 1-7. doi: 10.1016/j.vetmic.2020.108766

Worsley-Tonks, Katherine E. L., Miller, Elizabeth A., Gehrt, Stanley D., McKenzie, Shane C., Travis, Dominic A., Johnson, Timothy J. and Craft, Meggan E. (2020). Characterization of antimicrobial resistance genes in Enterobacteriaceae carried by suburban mesocarnivores and locally owned and stray dogs. Zoonoses and Public Health, 67 (4), 460-466. doi: 10.1111/zph.12691

Smith, Emily A., Miller, Elizabeth A., Weber, Bonnie P., Aguayo, Jeannette Munoz, Figueroa, Cristian Flores, Huisinga, Jared, Nezworski, Jill, Kromm, Michelle, Wileman, Ben and Johnson, Timothy J. (2020). Genomic landscape of Ornithobacterium rhinotracheale in commercial turkey production in the United States. Applied and Environmental Microbiology, 86 (11) e02874-19, 1-9. doi: 10.1128/AEM.02874-19

Divithotawela, Chandima, Pham, Amy, Ledger, Emma L., Hopkins, Peter, Wells, Timothy J. and Chambers, Daniel (2020). Treatment of life-threatening Pseudomonas aeruginosa infection by pheresis of inhibitory antibodies. Journal of Heart and Lung Transplantation, 39 (1), 87-89. doi: 10.1016/j.healun.2019.10.001

Clayton, Jonathan B., Shields-Cutler, Robin R., Hoops, Susan L., Al-Ghalith, Gabriel A., Sha, John C. M., Johnson, Timothy J. and Knights, Dan (2019). Bacterial community structure and function distinguish gut sites in captive red-shanked doucs (Pygathrix nemaeus). American Journal of Primatology, 81 (10-11). doi: 10.1002/ajp.22977

Salinas, Liseth, Cardenas, Paul, Johnson, Timothy J., Vasco, Karla, Graham, Jay and Trueba, Gabriel (2019). Diverse commensal Escherichia coli clones and plasmids disseminate antimicrobial resistance genes in domestic animals and children in a semirural community in Ecuador. mSphere, 4 (3) e00316-19, 1-10. doi: 10.1128/mSphere.00316-19

Fountain-Jones, Nicholas M., Clark, Nicholas J., Kinsley, Amy C., Carstensen, Michelle, Forester, James, Johnson, Timothy J., Miller, Elizabeth A., Moore, Seth, Wolf, Tiffany M. and Craft, Meggan E. (2019). Microbial associations and spatial proximity predict North American moose (Alces alces) gastrointestinal community composition. Journal of Animal Ecology, 89 (3) 1365-2656.13154, 1-12. doi: 10.1111/1365-2656.13154

Miller, Elizabeth A., Johnson, Timothy J., Omondi, George, Atwill, Edward R., Isbell, Lynne A., McCowan, Brenda and VanderWaal, Kimberly (2019). Assessing transmission of antimicrobial-resistant Escherichia coli in wild giraffe contact networks. Applied and Environmental Microbiology, 85 (1) e02136-18, 1-15. doi: 10.1128/AEM.02136-18

Johnson, Timothy J., Elnekave, Ehud, Miller, Elizabeth A., Munoz-Aguayo, Jeannette, Figueroa, Cristian Flores, Johnston, Brian, Nielson, Daniel W., Logue, Catherine M. and Johnson, James R. (2019). Phylogenomic analysis of extraintestinal pathogenic Escherichia coli sequence type 1193, an emerging multidrug-resistant clonal group. Antimicrobial Agents and Chemotherapy, 63 (1) e01913-18, 1-15. doi: 10.1128/AAC.01913-18

Morris, Faye C., Wells, Timothy J., Bryant, Jack A., Schager, Anna E., Sevastsyanovich, Yanina R., Squire, Derrick J. P., Marshall, Jennifer, Isom, Georgia L., Rooke, Jessica, Maderbocus, Riyaz, Knowles, Timothy J., Overduin, Michael, Rossiter, Amanda E., Cunningham, Adam F. and Henderson, Ian R. (2018). YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium. Infection and Immunity, 86 (11) e00829-17. doi: 10.1128/IAI.00829-17

Coggon, Carrie F., Jiang, Andrew, Goh, Kelvin G. K., Henderson, Ian R., Schembri, Mark A. and Wells, Timothy J. (2018). A novel method of serum resistance by Escherichia coli that causes urosepsis. mBio, 9 (3) e00920-18, e00920-18. doi: 10.1128/mbio.00920-18

Hammarlof, Disa L., Kroger, Carsten, Owen, Sian V., Canals, Rocio, Lacharme-Lora, Lizeth, Wenner, Nicolas, Schager, Anna E., Wells, Timothy J., Henderson, Ian R., Wigley, Paul, Hokamp, Karsten, Feasey, Nicholas A., Gordon, Melita A. and Hinton, Jay C. D. (2018). Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella. Proceedings of the National Academy of Sciences of the United States of America, 115 (11), E2614-E2623. doi: 10.1073/pnas.1714718115

Sevastsyanovich, Yanina R., Withers, David R., Marriott, Claire L., Morris, Faye C., Wells, Timothy J., Browning, Douglas F., Beriotto, Irene, Ross, Ewan, Ali, Hossam Omar, Wardius, Catherine A., Cunningham, Adam F., Henderson, Ian R. and Rossiter, Amanda E. (2017). Antigen localization influences the magnitude and kinetics of endogenous adaptive immune response to recombinant Salmonella vaccines. Infection and Immunity, 85 (12) e00593-17, e00593-17. doi: 10.1128/iai.00593-17

Kisiela, Dagmara I., Radey, Matthew, Paul, Sandip, Porter, Stephen, Polukhina, Kseniya, Tchesnokova, Veronika, Shevchenko, Sofiya, Chan, Diana, Aziz, Maliha, Johnson, Timothy J., Price, Lance B., Johnson, James R. and Sokurenko, Evgeni V. (2017). Inactivation of Transcriptional Regulators during Within-Household Evolution of Escherichia coli. Journal of Bacteriology, 199 (13) e00036. doi: 10.1128/JB.00036-17

Wells, Timothy J., Davison, John, Sheehan, Emma, Kanagasundaram, Suren, Spickett, Gavin, MacLennan, Calman A., Stockley, Robert A., Cunningham, Adam F., Henderson, Ian R. and De Soyza, Anthony (2017). The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies. American Journal of Respiratory and Critical Care Medicine, 195 (7), 955-958. doi: 10.1164/rccm.201603-0599LE

Clayton, Jonathan B., Vangay, Pajau, Hu Huang, , Ward, Tonya, Hillmann, Benjamin M., Al-Ghalith, Gabriel A., Travis, Dominic A., Ha Thang Long, , Bui Van Tuan, , Vo Van Minh, , Cabana, Francis, Nadler, Tilo, Toddes, Barbara, Murphy, Tami, Glander, Kenneth E., Johnson, Timothy J. and Knights, Dan (2016). Captivity humanizes the primate microbiome. Proceedings of the National Academy of Sciences of the United States of America, 113 (37), 10376-10381. doi: 10.1073/pnas.1521835113

Gohl, Daryl M., Vangay, Pajau, Garbe, John, MacLean, Allison, Hauge, Adam, Becker, Aaron, Gould, Trevor J., Clayton, Jonathan B., Johnson, Timothy J., Hunter, Ryan, Knights, Dan and Beckman, Kenneth B. (2016). Systematic improvement of amplicon marker gene methods for increased accuracy in microbiome studies. Nature Biotechnology, 34 (9), 942-+. doi: 10.1038/nbt.3601

Liu, Canying, Zheng, Huajun, Yang, Minjun, Xu, Zhuofei, Wang, Xiangru, Wei, Liuya, Tang, Biao, Liu, Feng, Zhang, Yanyan, Ding, Yi, Tang, Xibiao, Wu, Bin, Johnson, Timothy J., Chen, Huanchun and Tan, Chen (2015). Genome analysis and in vivo virulence of porcine extraintestinal pathogenic Escherichia coli strain PCN033. Bmc Genomics, 16 717. doi: 10.1186/s12864-015-1890-9

Browning, Douglas F., Bavro, Vassiliy N., Mason, Jessica L., Sevastsyanovich, Yanina R., Rossiter, Amanda E., Jeeves, Mark, Wells, Timothy J., Knowles, Timothy J., Cunningham, Adam F., Donald, James W., Palmer, Tracy, Overduin, Michael and Henderson, Ian R. (2015). Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion. Molecular Microbiology, 97 (4), 646-659. doi: 10.1111/mmi.13052

Wells, Timothy J., Whitters, Deborah, Sevastsyanovich, Yanina R., Heath, Jennifer N., Pravin, John, Goodall, Margaret, Browning, Douglas F., O'Shea, Matthew K., Cranston, Amy, De Soyza, Anthony, Cunningham, Adam F., MacLennan, Calman A., Henderson, Ian R. and Stockley, Robert A. (2014). Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing. Journal of Experimental Medicine, 211 (9), 1893-1904. doi: 10.1084/jem.20132444

Kim, Hyeun Bum, Singer, Randall S., Borewicz, Klaudyna, White, Bryan A., Sreevatsan, Srinand, Johnson, Timothy J., Espejo, Luis A. and Isaacson, Richard E. (2014). Effects of tylosin administration on C-reactive protein concentration and carriage of Salmonella enterica in pigs. American Journal of Veterinary Research, 75 (5), 460-467. doi: 10.2460/ajvr.75.5.460

Browning, Douglas F., Matthews, Sophie A., Rossiter, Amanda E., Sevastsyanovich, Yanina R., Jeeves, Mark, Mason, Jessica L., Wells, Timothy J., Wardius, Catherine A., Knowles, Timothy J., Cunningham, Adam F., Bavro, Vassiliy N., Overduin, Michael and Henderson, Ian R. (2013). Mutational and topological analysis of the Escherichia coli BamA protein. PLoS ONE, 8 (12) e84512, e84512. doi: 10.1371/journal.pone.0084512

Franca, Fernanda L. S., Wells, Timothy J., Browning, Douglas F., Nogueira, Raquel Tayar, Sarges, Felipe Silva, Pereira, Ana Claudia, Cunningham, Adam F., Lucheze, Kely, Paula Rosa, Ana Claudia, Henderson, Ian R. and de Luna, Maria das Gracas (2013). Genotypic and phenotypic characterisation of enteroaggregative Escherichia coli from children in Rio de Janeiro, Brazil. PLoS ONE, 8 (7) e69971, e69971. doi: 10.1371/journal.pone.0069971

Browning, Douglas F., Wells, Timothy J., Franca, Fernanda L. S., Morris, Faye C., Sevastsyanovich, Yanina R., Bryant, Jack A., Johnson, Matthew D., Lund, Peter A., Cunningham, Adam F., Hobman, Jon L., May, Robin C., Webber, Mark A. and Henderson, Ian R. (2013). Laboratory adapted Escherichia coli K-12 becomes a pathogen of Caenorhabditis elegans upon restoration of O antigen biosynthesis. Molecular Microbiology, 87 (5), 939-950. doi: 10.1111/mmi.12144

Johnson, Timothy J., Bielak, Eliza M., Fortini, Daniela, Hansen, Lars Hestbjerg, Hasman, Henrik, Debroy, Chitrita, Nolan, Lisa K. and Carattoli, Alessandra (2012). Expansion of the IncX plasmid family for improved identification and typing of novel plasmids in drug-resistant Enterobacteriaceae. Plasmid, 68 (1), 43-50. doi: 10.1016/j.plasmid.2012.03.001

Sevastsyanovich, Yanina R., Leyton, Denisse L., Wells, Timothy J., Wardius, Catherine A., Tveen-Jensen, Karina, Morris, Faye C., Knowles, Timothy J., Cunningham, Adam F., Cole, Jeffrey A. and Henderson, Ian R. (2012). A generalised module for the selective extracellular accumulation of recombinant proteins. Microbial Cell Factories, 11 (69) 69. doi: 10.1186/1475-2859-11-69

Selkrig, Joel, Mosbahi, Khedidja, Webb, Chaille T., Belousoff, Matthew J., Perry, Andrew J., Wells, Timothy J., Morris, Faye, Leyton, Denisse L., Totsika, Makrina, Phan, Minh-Duy, Celik, Nermin, Kelly, Michelle, Oates, Clare, Hartland, Elizabeth L., Robins-Browne, Roy M., Ramarathinam, Sri Harsha, Purcell, Anthony W., Schembri, Mark A., Strugnell, Richard A., Henderson, Ian R., Walker, Daniel and Lithgow, Trevor (2012). Discovery of an archetypal protein transport system in bacterial outer membranes. Nature Structural and Molecular Biology, 19 (5), 506-510. doi: 10.1038/nsmb.2261

Totsika, Makrina, Wells, Timothy J., Beloin, Christophe, Valle, Jaione, Allsopp, Luke P., King, Nathan P., Ghigo, Jean-Marc and Schembri, Mark A. (2012). Molecular characterization of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli. Applied and Environmental Microbiology, 78 (7), 2179-2189. doi: 10.1128/AEM.06680-11

Leyton, Denisse L., Sevastsyanovich, Yanina R., Browning, Douglas F., Rossiter, Amanda E., Wells, Timothy J., Fitzpatrick, Rebecca E., Overduin, Michael, Cunningham, Adam F. and Henderson, Ian R. (2011). Size and conformation limits to secretion of disulfide-bonded loops in autotransporter proteins. Journal of Biological Chemistry, 286 (49), 42283-42291. doi: 10.1074/jbc.M111.306118

Sandford, Erin E., Orr, Megan, Balfanz, Emma, Bowerman, Nate, Li, Xianyao, Zhou, Huaijun, Johnson, Timothy J., Kariyawasam, Subhashinie, Liu, Peng, Nolan, Lisa K. and Lamont, Susan J. (2011). Spleen transcriptome response to infection with avian pathogenic Escherichia coli in broiler chickens. Bmc Genomics, 12 469. doi: 10.1186/1471-2164-12-469

Fernandez-Alarcon, Claudia, Singer, Randall S. and Johnson, Timothy J. (2011). Comparative Genomics of Multidrug Resistance-Encoding IncA/C Plasmids from Commensal and Pathogenic Escherichia coli from Multiple Animal Sources. Plos One, 6 (8) e23415. doi: 10.1371/journal.pone.0023415

Johnson, Timothy J., Fernandez-Alarcon, Claudia, Bojesen, Anders Miki, Nolan, Lisa K., Trampel, Darrell W. and Seemann, Torsten (2011). Complete Genome Sequence of Gallibacterium anatis Strain UMN179, Isolated from a Laying Hen with Peritonitis. Journal of Bacteriology, 193 (14), 3676-3677. doi: 10.1128/JB.05177-11

Crossman, L. C., Chaudhuri, R. R., Beatson, S. A., Wells, T. J., Desvaux, M., Cunningham, A. F., Petty, N. K., Mahon, V., Brinkley, C., Hobman, J. L., Savarino, S. J., Turner, S. M., Pallen, M. J., Penn, C. W., Parkhill, J., Turner, A. K., Johnson, T. J., Thomson, N. R., Smith, S. G. J. and Henderson, I. R. (2010). A commensal gone bad: Complete genome sequence of the prototypical enterotoxigenic escherichia coli strain H10407. Journal of Bacteriology, 192 (21), 5822-5831. doi: 10.1128/JB.00710-10

Wells, Timothy J., Totsika, Makrina and Schembri, Mark A. (2010). Autotransporters of Escherichia coli: A sequence-based characterization. Microbiology, 156 (8), 2459-2469. doi: 10.1099/mic.0.039024-0

Heras, B, Totsika, M, Jarrott, R, Shouldice, SR, Guncar, G, Achard, MES, Wells, TJ, Argente, MP, McEwan, AG and Schembri, MA (2010). Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium. Journal of Biological Chemistry, 285 (24), 18423-18432. doi: 10.1074/jbc.M110.101360

Johnson, Timothy J., Jordan, Dianna, Kariyawasam, Subhashinie, Stell, Adam L., Bell, Nathan P., Wannemuehler, Yvonne M., Fernandez-Alarcon, Claudia, Li, Ganwu, Tivendale, Kelly A., Logue, Catherine M. and Nolan, Lisa K. (2010). Sequence Analysis and Characterization of a Transferable Hybrid Plasmid Encoding Multidrug Resistance and Enabling Zoonotic Potential for Extraintestinal Escherichia coli. Infection and Immunity, 78 (5), 1931-1942. doi: 10.1128/IAI.01174-09

Allsopp, Luke P., Totsika, Makrina, Tree, Jai J., Ulett, Glen C., Mabbett, Amanda N., Wells, Timothy J., Kobe, Bostjan, Beatson, Scott A. and Schembri, Mark A. (2010). UpaH is a newly identified autotransporter protein that contributes to biofilm formation and bladder colonization by uropathogenic Escherichia coli CFT073. Infection and Immunity, 78 (4), 1659-1669. doi: 10.1128/IAI.01010-09

Wells, Timothy J., McNeilly, Tom N., Totsika, Makrina, Mahajan, Arvind, Gally, David L. and Schembri, Mark A. (2009). The Escherichia coli O157:H7 EhaB autotransporter protein binds to laminin and collagen I and induces a serum IgA response in O157:H7 challenged cattle. Environmental Microbiology, 11 (7), 1803-1814. doi: 10.1111/j.1462-2920.2009.01905.x

Wells, T.J., Sherlock, O., Rivas, L., Mahajan, A., Beatson, S.A., Torpdahl, M., Webb, R.I., Allsopp, L., Gobius, K., Gally, D.L. and Schembri, M.A. (2008). EhaA is a novel autotransporter protein of enterohemorrhagic Escherichia coli O157:H7 that contributes to adhesion and biofilm formation. Environmental Microbiology, 10 (3), 589-604. doi: 10.1111/j.1462-2920.2007.01479.x

Wells, T. J., Tree, J. J., Ulett, G. C. and Schembri, M. A. (2007). Autotransporter proteins: novel targets at the bacterial cell surface. Fems Microbiology Letters, 274 (2), 163-172. doi: 10.1111/j.1574-6968.2007.00833.x

Rodriguez-Siek, KE, Giddings, CW, Doetkott, C, Johnson, TJ and Nolan, LK (2005). Characterizing the APEC pathotype. Veterinary Research, 36 (2), 241-256. doi: 10.1051/vetres:2004057

Johnson, TJ, Skyberg, J and Nolan, LK (2004). Multiple antimicrobial resistance region of a putative virulence plasmid from an Escherichia coli isolate incriminated in avian colibacillosis. Avian Diseases, 48 (2), 351-360. doi: 10.1637/7121

Ledger, Emma, Smith, Daniel, Teh, Jing Jie, Wood, Michelle, Whibley, Page, Morrison, Mark, Goldberg, Joanna, Reid, David and Wells, Timothy (2024). Does a leopard change its spots? Pseudomonas aeruginosa in cystic fibrosis after CFTR modulation. Abstracts of the 15th Australasian Cystic Fibrosis Conference, Brisbane, QLD, Australia, 2–4 August 2024. Richmond, VIC, Australia: John Wiley & Sons.

Cameron, A., Giri, R., Begun, J., Wells, T., Bergot, A. S. and Thomas, R. (2023). Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis. EULAR 2023 European Congress of Rheumatology, Milan, Italy, 31 May-3 June 2023. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2023-eular.1346

Souza-Fonseca-Guimaraes, Fernando, Rossi, Gustavo Rodrigues, Wells, Timothy and McCulloch, Timothy Ryan (2023). TIGIT limits anti-bacterial immunity and is a potential target for immunotherapy. IMMUNOLOGY2023™ Meeting, Washington, DC, United States, 11 - 15 May 2023. Rockville, MD, United States: The American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.64.14

McCulloch, Timothy R., Rossi, Gustavo Rodrigues, Lam, Allie, Wong, Joshua, Kane, Lawrence P., Herold, Marco, Wells, Timothy and Souza-Fonseca-Guimaraes, Fernando (2023). Differential regulation of natural killer cells by tumor necrosis factor receptors 1 and 2. Immunology 2023™ Meeting, Washington, DC United States, 11-15 May 2023. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.210.supp.72.28

Peichel, Claire, Manjankattil, Shijinarah, Dewi, Grace, Akhtar, Luna, Bina, Peter, Creek, Medora, Deniz, Kerem, Hobbs, John, Wichmann, Elaina, Feist, Emma, Schlosser, Mikayla, Johnson, Timothy J. J., Noll, Sally and Johny, Anup Kollanoor (2022). Reduction of Salmonella Reading Using a Dairy-Originated Probiotic Bacterium, Propionibacterium Freudenreichii in Combination with a Live Attenuated Salmonella Typhimurium Vaccine in Growing Turkeys. CARY: OXFORD UNIV PRESS INC. doi: 10.1093/jas/skac247.463

Divithotawela, C., Pham, A., Ledger, E. L., Hopkins, P., Tan, M., Yerkovich, S., Wells, T. J. and Chambers, D. C. (2020). A Novel Pseudomonas aeruginosa Virulence Factor Predicts CLAD and Death after Lung Transplantation. International Society for Heart and Lung Transplantation 40th Annual Meeting and Scientific Sessions, Online, 22 - 25 April 2020. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2020.01.1265

Divithotawela, C., Pham, A., Ledger, E. L., Hopkins, P., Tan, M., Yerkovich, S., Wells, T. J. and Chambers, D. C. (2020). A Novel Pseudomonas aeruginosa Virulence Factor Predicts CLAD and Death after Lung Transplantation. 40th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), Montreal, Canada, 22-25 April 2020. New York, NY United States: Elsevier.

Baillet, Athan, Bhuyan, Zaied Ahmed, Douillard, Claire, Bozon, Aurelie, Armitage, Charles, Romand, Xavier, Minh Vu Chuong Nguyen,, Favier, Bertrand, Wells, Timothy, Beagley, Kenneth and Thomas, Ranjeny (2017). Chlamydia-Infected Macrophages: "Trojan Horses" for Dissemination of IL-23 and TNF-Mediated Inflammation in SKG Mouse Reactive Arthritis. 2017 ACR/ARHP Pediatric Rheumatology Symposium, San Diego, CA, United States, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.

Gresshoff, PM, Gualtieri, G, Laniya, T, Indrasumunar, A, Miyahara, A, Nontachaiyapoom, S, Wells, T, Biswas, B, Chan, PK, Scott, P, Kinkema, M, Djordjevic, M, Hoffmann, D, Pregelj, L, Buzas, DM, Li, DX, Men, A, Jiang, Q, Hwang, CH and Carroll, BJ (2005). Functional genomics of the regulation of nodule number in legumes. 14th International Nitrogen Fixation Congress, Beijing, China, 27 October - 1 November 2004. The Netherlands: Springer. doi: 10.1007/1-4020-3570-5

Gresshoff, P. M., Carroll, B. J., Gualtieri Gonzalez, G. S., Vickers, C., Kuen, P., Huang, C., Scott, P. T., Kinkema, M. D., Men, A., Stiller, J., Jiang, Q., Laniya, T.S., Buzas, D. M., Miyahara, A., Indrasumunar, A., Nontachaiyapoom, S., Hoffmann, D., Biswas, B., Wells, T. J., So, H., Pregelj, L. and Dong, X. (2004). Functional genomic analysis of nodule development in soybean and Lotus Japonicus. Com Bio 2004, Intercontinental Burswood Resort, Perth, Australia, 26-30 September, 2004.

Wells, Timothy (2008). Identification and characterisation of novel autotransporters of enterohaemorrhagic escherichia coli O157:H7. PhD Thesis, School of Chemistry and Molecular Bioscience, The University of Queensland. doi: 10.14264/178070

Associate Professor Timothy Wells

Researcher biography

Publications

Book Chapter

Journal Articles

Conference Papers

Thesis