Professor Nikolas Haass
Professor
Frazer Institute
Director (Research Training)
Faculty of Medicine
Affiliate of Dermatology Research Centre
Dermatology Research Centre
+61 7 344 37087
Professor Nikolas Haass leads the Experimental melanoma therapy group.
Nikolas Haass is a Professor at The University of Queensland Diamantina Institute/Translational Research Institute, Honorary Associate Professor at The University of Sydney and Adjunct Associate faculty member at the Centenary Institute.
After obtaining his PhD at the German Cancer Research Center/ Heidelberg University, he trained as a dermatologist with a focus on cutaneous oncology at the University Hospital Hamburg-Eppendorf, Germany. He then spent five years at the Wistar Institute (University of Pennsylvania) in Philadelphia, as a post-doctoral fellow funded by the German Research Foundation. As a Cameron Melanoma Research Fellow from October 2007 to February 2013, he headed the group, ‘Experimental Melanoma Therapy’ at the Centenary Institute.
In March 2013 he commenced his current position at UQDI. Using cutting-edge technology, such as real-time imaging of melanoma cells in 3D culture and in vivo, he and his team investigate the biology of tumour heterogeneity and the role of differential subpopulations of melanoma cells in melanomagenesis with the goal to develop novel therapeutic approaches by simultaneously targeting these differential subpopulations.
Research projects
- Targeting the actin cytoskeleton as a strategy for melanoma therapy
- Disarming Tumor Escape Mechanisms in Human Melanoma With Epigenetic Modifiers
- Real-time cell cycle imaging of melanoma cells in vitro and in vivo
- Defining the role of Microphthalmia-associated Transcription Factor (MITF) in melanoma growth by real-time cell cycle imaging
- Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy
- Characterization of the intrinsic, non-phototoxic, effects of Rose Bengal on melanoma
- Induction of endoplasmic reticulum stress as a strategy for melanoma therapy
- Cell-cell and cell-matrix interactions between melanoma and its tumour microenvironment
Researcher biography
I am a clinician scientist and academic leader with research in melanoma cell biology and experimental melanoma therapy. I received my degree in medicine from the University of Heidelberg, Germany (1990-1998). I graduated summa cum laude with a PhD in Cell Biology from the University of Heidelberg (1993-1999) and trained in clinical dermatology at the University of Hamburg, Germany (1999-2003). In 2003 I moved to Philadelphia, PA, to work as a post-doctoral fellow in Meenhard Herlyn's lab at The Wistar Institute (2003-2007). From there I was recruited as an associate faculty member to the Centenary Institute/University of Sydney (2007-2013). In 2013 I commenced a position as Associate Professor for Cutaneous Oncology at University of Queensland Diamantina Institute (now Frazer Institute) and was promoted to full Professor in April 2016.
Book Chapters
Spoerri, Loredana, Beaumont, Kimberley A., Anfosso, Andrea, Murphy, Ryan J., Browning, Alexander P., Gunasingh, Gency and Haass, Nikolas K. (2024). Real-time cell cycle imaging in a 3D cell culture model of melanoma, quantitative analysis, optical clearing, and mathematical modeling. 3D cell culture: methods and protocols. (pp. 291-310) edited by Zuzana Sumbalova Koledova. New York, NY, United States: Humana. doi: 10.1007/978-1-0716-3674-9_19
Fernandez-Peñas, Pablo, Jones-Caballero, María and Haass, Nikolas (2023). Melanocytes and melanogenesis. Schachner and Hansen's pediatric dermatology. (pp. 1093-1097) edited by Antonio Torrelo, Angela Hernández-Martín, Elaine C. Siegfried, Anne W. Lucky, Robert A. Silverman, Elena Pope and Karen Wiss. New Delhi, India & London, United Kingdom: Jaypee Brothers Medical Publishers. doi: 10.5005/jp/books/18588_59
Spoerri, Loredana, Beaumont, Kimberley A., Anfosso, Andrea and Haass, Nikolas K. (2017). Real-time cell cycle imaging in a 3D cell culture model of melanoma. In 3D cell culture: methods and protocols (pp. 401-416) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-7021-6_29
Kuphal, Silke and Haass, Nikolas K. (2017). Cell–cell contacts in melanoma and the tumor microenvironment. Melanoma development: molecular biology, genetics and clinical application. (pp. 227-269) edited by Anja K. Bosserhoff. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-41319-8_9
Spoerri, Loredana, Oo, Zay Yar, Larsen, Jill E., Haass, Nikolas K., Gabrielli, Brian and Pavey, Sandra (2015). Cell cycle checkpoint and DNA damage response defects as anticancer targets: from molecular mechanisms to therapeutic opportunities.. Stress response pathways in cancer: from molecular targets to novel therapeutics. (pp. 29-49) edited by Georg T. Wondrak. Dordrecht: Springer Science+Business Media. doi: 10.1007/978-94-017-9421-3_3
Tonnessen, Crystal A. and Haass, Nikolas K. (2015). Melanoma: From tumor-specific mutations to a new molecular taxonomy and innovative therapeutics. Personalized treatment options in dermatology. (pp. 7-27) edited by Thomas Bieber and Frank Nestle. Heidelberg, Germany: Springer. doi: 10.1007/978-3-662-45840-2_2
Haass, Nikolas K. (2014). The Grey-headed Albatross conundrum at the Australian east coast. The Petrel: Annual Report for Southport The Brisbane Seabird Study Group SOSSA, Northern Sector. (pp. 96-107) edited by Paul Walbridge. Brisbane, QLD Australia: SOSSA.
Haass, N. K. and Bauer, H.-G. (2011). Egretta schistacea: Kuestenreiher. Nicht-Singvögel: Rheidae (Nandus) - Phoenicopteridae (Flamingos). (pp. 266-268) edited by Jochen Hölzinger and Hans-Günther Bauer. Stuttgart, Germany: Ulmer Eugen Verlag.
Kuphal, Silke and Haass, Nikolas K. (2011). Cell-cell and cell-matrix contacts in melanoma and the tumor microenvironment. Melanoma Development: Molecular Biology, Genetics and Clinical Application. (pp. 181-215) edited by Anja Bosserhoff. Vienna, Austria: SpringerWienNewYork. doi: 10.1007/978-3-7091-0371-5
Haass, Nikolas K., Hoeller, Christoph and Herlyn, Meenhard (2008). Targeting signaling pathways: in the search of melanoma's Achilles' heel. Regulation of Gene Expression in the Tumor Environment. (pp. 27-42) edited by Menashe Bar-Eli. London, UK: Springer. doi: 10.1007/978-1-4020-8341-9
Haass, Nikolas K., Houdek, Pia, Wladykowski, Ewa, Moll, Ingrid and Brandner, Johanna M. (2003). Expression patterns of tight junction proteins in Merkel cell carcinoma. The Merkel Cell: Structure-Development-Function-Cancerogenesis. Proceedings of the International Merkel Cell Symposium, Hamburg 2002. (pp. 223-226) edited by Klaus I. Baumann, Zdenek Halata and Ingrid Moll. Berlin, Germany: Springer-Verlag. doi: 10.1007/978-3-662-10358-6_32
Haass, Nikolas K., Houdek, Pia, Brandner, Johanna M. and Moll, Ingrid (2003). Expression patterns of connexins in Merkel cell carcinoma and adjacent epidermis. The Merkel Cell: Structure-Development-Function-Cancerogenesis. Proceedings of the International Merkel Cell Symposium, Hamburg 2002. (pp. 219-222) edited by Klaus I. Baumann, Zdenek Halata and Ingrid Moll. Berlin, Germany: Springer-Verlag. doi: 10.1007/978-3-662-10358-6_31
Siegel, H. and Haass, N. K. (1997). Graureiher: Ardea cinerea. Avifauna von Hessen. (pp. 5.1.7.1.1-5.1.7.1.9) edited by Karl-Heinz Berck. Wiesbaden, Germany: Hessische Gesellschaft für Ornithologie und Naturschutz.
Kreuziger, J., Werner, M., Haass, N. K., Haass, C. and Siegel, H. (1997). Kormoran: Phalacrocorax carbo. Avifauna von Hessen. (pp. 4.2.1.1.1-4.2.1.1.13) edited by Karl-Heinz Berck. Wiesbaden, Germany: Hessische Gesellschaft für Ornithologie und Naturschutz.
Journal Articles
Ju, Robert J., Falconer, Alistair D., Schmidt, Christanny J., Martinez, Marco A. Enriquez, Dean, Kevin M., Fiolka, Reto P., Sester, David P., Nobis, Max, Timpson, Paul, Lomakin, Alexis J., Danuser, Gaudenz, White, Melanie D., Haass, Nikolas K., Oelz, Dietmar B. and Stehbens, Samantha J. (2024). Compression-dependent microtubule reinforcement enables cells to navigate confined environments. Nature Cell Biology, 26 (9), 1520-1534. doi: 10.1038/s41556-024-01476-x
Malekan, Mohammad, Haass, Nikolas K., Rokni, Ghasem Rahmatpour, Gholizadeh, Nasim, Ebrahimzadeh, Mohammad Ali and Kazeminejad, Armaghan (2024). VEGF/VEGFR axis and its signaling in melanoma: current knowledge toward therapeutic targeting agents and future perspectives. Life Sciences, 345 122563, 122563. doi: 10.1016/j.lfs.2024.122563
Ke, Yazi D., van Hummel, Annika, Au, Carol, Chan, Gabriella, Lee, Wei Siang, van der Hoven, Julia, Przybyla, Magdalena, Deng, Yuanyuan, Sabale, Miheer, Morey, Nicolle, Bertz, Josefine, Feiten, Astrid, Ippati, Stefania, Stevens, Claire H., Yang, Shu, Gladbach, Amadeus, Haass, Nikolas K., Kril, Jillian J., Blair, Ian P., Delerue, Fabien and Ittner, Lars M. (2024). Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice. Neuron, 112 (8), 1249-1264.e8. doi: 10.1016/j.neuron.2024.01.022
Murphy, Ryan J., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2023). Formation and growth of co-culture tumour spheroids: new compartment-based mathematical models and experiments. Bulletin of Mathematical Biology, 86 (1) 8, 1-434. doi: 10.1007/s11538-023-01229-1
Menon, Dinoop Ravindran, Hammerlindl, Heinz, Gimenez, Gregory, Hammerlindl, Sabrina, Zuegner, Elmar, Torrano, Joachim, Bordag, Natalie, Emran, Abdullah Al, Giam, Maybelline, Denil, Simon, Pavelka, Norman, Tan, Aik-Choon, Sturm, Richard A., Haass, Nikolas K., Rancati, Giulia, Herlyn, Meenhard, Magnes, Christoph, Eccles, Michael R., Fujita, Mayumi and Schaider, Helmut (2023). H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase. Drug Resistance Updates, 71 100993, 100993. doi: 10.1016/j.drup.2023.100993
Wallingford, Courtney K., Demeshko, Anastassia, Krishnakripa, Asha Krishnankutty, Smit, Darren J., Duffy, David L., Betz-Stablein, Brigid, Pflugfelder, Annette, Jagirdar, Kasturee, Holland, Elizabeth, Mann, Graham J., Primiero, Clare A., Yanes, Tatiane, Malvehy, Josep, Badenas, Cèlia, Carrera, Cristina, Aguilera, Paula, Olsen, Catherine M., Ward, Sarah V., Haass, Nikolas K., Sturm, Richard A., Puig, Susanna, Whiteman, David C., Law, Matthew H., Cust, Anne E., Potrony, Miriam, Soyer, H. Peter and McInerney-Leo, Aideen M. (2023). The MC1R r allele does not increase melanoma risk in MITF E318K carriers. British Journal of Dermatology, 188 (6), 770-776. doi: 10.1093/bjd/ljad041
Basnayake, B. W. M. Thilini J., Leo, Paul, Rao, Sudha, Vasani, Sarju, Kenny, Lizbeth, Haass, Nikolas K. and Punyadeera, Chamindie (2023). Head and neck cancer patient-derived tumouroid cultures: opportunities and challenges. British Journal of Cancer, 128 (10), 1807-1818. doi: 10.1038/s41416-023-02167-4
Murphy, Ryan J., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2023). Growth and adaptation mechanisms of tumour spheroids with time-dependent oxygen availability. PLoS Computational Biology, 19 (1) e1010833, 1-29. doi: 10.1371/journal.pcbi.1010833
Gunasingh, Gency, Browning, Alexander P. and Haass, Nikolas K. (2022). Rapid Optical Clearing for Semi-High-Throughput Analysis of Tumor Spheroids. Journal of Visualized Experiments, 2022 (186) e64103. doi: 10.3791/64103
Fane, Mitchell E., Chhabra, Yash, Spoerri, Loredana, Simmons, Jacinta L., Ludwig, Raquelle, Bonvin, Elise, Goding, Colin R., Sturm, Richard A., Boyle, Glen M., Haass, Nikolas K., Piper, Michael and Smith, Aaron G. (2022). Reciprocal regulation of BRN2 and NOTCH1/2 signaling synergistically drives melanoma cell migration and invasion. Journal of Investigative Dermatology, 142 (7), 1845-1857. doi: 10.1016/j.jid.2020.12.039
Chauvistré, Heike, Shannan, Batool, Daignault-Mill, Sheena M., Ju, Robert J., Picard, Daniel, Egetemaier, Stefanie, Váraljai, Renáta, Gibhardt, Christine S., Sechi, Antonio, Kaschani, Farnusch, Keminer, Oliver, Stehbens, Samantha J., Liu, Qin, Yin, Xiangfan, Jeyakumar, Kirujan, Vogel, Felix C. E., Krepler, Clemens, Rebecca, Vito W., Kubat, Linda, Lueong, Smiths S., Forster, Jan, Horn, Susanne, Remke, Marc, Ehrmann, Michael, Paschen, Annette, Becker, Jürgen C., Helfrich, Iris, Rauh, Daniel, Kaiser, Markus ... Roesch, Alexander (2022). Persister state-directed transitioning and vulnerability in melanoma. Nature Communications, 13 (1) 3055, 3055. doi: 10.1038/s41467-022-30641-9
Shariev, Artur, Painter, Nicole, Reeve, Vivienne E., Haass, Nikolas K., Rybchyn, Mark S., Ince, Furkan A., Mason, Rebecca S. and Dixon, Katie M. (2022). PTEN: a novel target for vitamin D in melanoma. The Journal of Steroid Biochemistry and Molecular Biology, 218 106059, 1-10. doi: 10.1016/j.jsbmb.2022.106059
Klowss, Jonah J., Browning, Alexander P., Murphy, Ryan J., Carr, Elliot J., Plank, Michael J., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2022). A stochastic mathematical model of 4D tumour spheroids with real-time fluorescent cell cycle labelling. Journal of the Royal Society. Interface, 19 (189) 20210903, 20210903. doi: 10.1098/rsif.2021.0903
Murphy, Ryan J., Browning, Alexander P., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2022). Designing and interpreting 4D tumour spheroid experiments. Communications Biology, 5 (1) 91, 91. doi: 10.1038/s42003-022-03018-3
Browning, Alexander P., Sharp, Jesse A., Murphy, Ryan J., Gunasingh, Gency, Lawson, Brodie, Burrage, Kevin, Haass, Nikolas K. and Simpson, Matthew (2021). Quantitative analysis of tumour spheroid structure. eLife, 10 e73020. doi: 10.7554/elife.73020
Proctor, Martina, Gonzalez Cruz, Jazmina L., Daignault-Mill, Sheena M., Veitch, Margaret, Zeng, Bijun, Ehmann, Anna, Sabdia, Muhammed, Snell, Cameron, Keane, Colm, Dolcetti, Riccardo, Haass, Nikolas K., Wells, James W. and Gabrielli, Brian (2021). Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression. Cancers, 13 (15) 3733, 1-19. doi: 10.3390/cancers13153733
Li, D., Ryu, E., Saeidian, A. H., Youssefian, L., Oliphant, E., Terry, S. F., Tong, P. L., Uitto, J., Haass, N. K. and Li, Q. (2021). GGCX mutations in a patient with PXE/CL-like overlapping phenotype. British Journal of Dermatology, 184 (6) , 1170-1174. doi: 10.1111/bjd.19576
Spoerri, Loredana, Gunasingh, Gency and Haass, Nikolas K. (2021). Fluorescence-based quantitative and spatial analysis of tumour spheroids: a proposed tool to predict patient-specific therapy response. Frontiers in Digital Health, 3 668390, 1-19. doi: 10.3389/fdgth.2021.668390
Gavagnin, Enrico, Vittadello, Sean T., Gunasingh, Gency, Haass, Nikolas K., Simpson, Matthew J., Rogers, Tim and Yates, Christian A. (2021). Synchronised oscillations in growing cell populations are explained by demographic noise. Biophysical Journal, 120 (8), 1314-1322. doi: 10.1016/j.bpj.2021.02.017
Ippati, Stefania, Deng, Yuanyuan, van der Hoven, Julia, Heu, Celine, van Hummel, Annika, Chua, Sook Wern, Paric, Esmeralda, Chan, Gabriella, Feiten, Astrid, Fath, Thomas, Ke, Yazi D., Haass, Nikolas K. and Ittner, Lars M. (2021). Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity. Proceedings of the National Academy of Sciences, 118 (12) e2011876118, e2011876118. doi: 10.1073/pnas.2011876118
Jin, Wang, Spoerri, Loredana, Haass, Nikolas K. and Simpson, Matthew J. (2021). Mathematical model of tumour spheroid experiments with real-time cell cycle imaging. Bulletin of Mathematical Biology, 83 (5) 44, 1-23. doi: 10.1007/s11538-021-00878-4
Vittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2021). A novel mathematical model of heterogeneous cell proliferation. Journal of Mathematical Biology, 82 (5) 34, 34. doi: 10.1007/s00285-021-01580-8
Fujimura, Taku, Fujisawa, Yasuhiro, Otsuka, Atsushi and Haass, Nikolas K. (2020). Editorial: recent developments in therapies and diagnostic tools for melanoma and non-melanoma skin cancer. Frontiers in Medicine, 7 613152, 613152. doi: 10.3389/fmed.2020.613152
Guo, Dajiang, Beaumont, Kimberley A., Sharp, Danae M., Lui, Goldie Y. L., Weninger, Wolfgang, Haass, Nikolas K. and Tikoo, Shweta (2020). Abrogation of RAB27A expression transiently affects melanoma cell proliferation. Pigment Cell and Melanoma Research, 33 (6), 889-894. doi: 10.1111/pcmr.12903
Vittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2020). Examining go-or-grow using fluorescent cell-cycle indicators and cell-cycle-inhibiting drugs. Biophysical journal, 118 (6), 1243-1247. doi: 10.1016/j.bpj.2020.01.036
Vittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2019). Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation. Journal of The Royal Society Interface, 16 (157) 20190382, 20190382. doi: 10.1098/rsif.2019.0382
Oo, Zay Yar, Proctor, Martina, Stevenson, Alexander J., Nazareth, Deborah, Fernando, Madushan, Daignault, Sheena M., Lanagan, Catherine, Walpole, Sebastian, Bonazzi, Vanessa, Škalamera, Dubravka, Snell, Cameron, Haass, Nikolas K., Larsen, Jill E. and Gabrielli, Brian (2019). Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine. Molecular Oncology, 13 (7) 1878-0261.12497, 1503-1518. doi: 10.1002/1878-0261.12497
Guo, Dajiang, Lui, Goldie Y. L., Lai, Siew Li, Wilmott, James S., Tikoo, Shweta, Jackett, Louise A., Quek, Camelia, Brown, Darren L., Sharp, Danae M., Kwan, Rain Y. Q., Chacon, Diego, Wong, Jason H., Beck, Dominik, van Geldermalsen, Michelle, Holst, Jeff, Thompson, John F., Mann, Graham J., Scolyer, Richard A., Stow, Jennifer L., Weninger, Wolfgang, Haass, Nikolas K. and Beaumont, Kimberley A. (2019). RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. International Journal of Cancer, 144 (12), 3070-3085. doi: 10.1002/ijc.32064
Guo, Dajiang, Tikoo, Shweta and Haass, Nikolas K. (2019). RAB27A-mediated melanoma exosomes: promoters of invasion and metastasis. Translational Cancer Research, 8 (3), 732-735. doi: 10.21037/tcr.2019.04.25
Lee, Erinna F., Harris, Tiffany J., Tran, Sharon, Evangelista, Marco, Arulananda, Surein, John, Thomas, Ramnac, Celeste, Hobbs, Chloe, Zhu, Haoran, Gunasingh, Gency, Segal, David, Behren, Andreas, Cebon, Jonathan, Dobrovic, Alexander, Mariadason, John M., Strasser, Andreas, Rohrbeck, Leona, Haass, Nikolas K., Herold, Marco J. and Fairlie, W. Douglas (2019). BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival. Cell Death & Disease, 10 (5) 342, 342. doi: 10.1038/s41419-019-1568-3
Emran, Abdullah Al, Chinna Chowdary, Brinda Reddy, Ahmed, Farzana, Hammerlindl, Heinz, Huefner, Antje, Haass, Nikolas K., Schuehly, Wolfgang and Schaider, Helmut (2019). Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma. Cancer Medicine, 8 (3), 1186-1196. doi: 10.1002/cam4.1978
Emran, Abdullah Al, Chinna Chowdary, Brinda Reddy, Ahmed, Farzana, Hammerlindl, Heinz, Huefner, Antje, Haass, Nikolas K., Schuehly, Wolfgang and Schaider, Helmut (2019). Cover image. Cancer Medicine, 8 (3), i-i. doi: 10.1002/cam4.2129
Simpson, Matthew J., Jin, Wang, Vittadello, Sean T., Tambyah, Tamara A., Ryan, Jacob M., Gunasingh, Gency, Haass, Nikolas K. and McCue, Scott W. (2018). Stochastic models of cell invasion with fluorescent cell cycle indicators. Physica A: Statistical Mechanics and its Applications, 510, 375-386. doi: 10.1016/j.physa.2018.06.128
Ju, Robert J., Stehbens, Samantha J. and Haass, Nikolas K. (2018). The role of melanoma cell-stroma interaction in cell motility, invasion, and metastasis. Frontiers in Medicine, 5 (NOV) 307, 1-9. doi: 10.3389/fmed.2018.00307
Stehbens, Samantha J., Ju, Robert J., Adams, Mark N., Perry, Samuel, Haass, Nikolas K., Bryant, David M. and Pollock, Pamela M. (2018). FGFR2b activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer. Journal of Cell Science, 131 (15) jcs.213678, 1-16. doi: 10.1242/jcs.213678
Oo, Zay Yar, Stevenson, Alexander J., Proctor, Martina A., Daignault, Sheena M., Walpole, Sebastian, Lanagan, Catherine, Chen, James, Skalamera, Dubravka, Spoerri, Loredana, Ainger, Stephen, Sturm, Richard A, Haass, Nikolas K and Gabrielli, Brian (2018). Endogenous replication stress marks melanomas sensitive to CHEK1 inhibitors in vivo. Clinical Cancer Research, 24 (12), 2901-2912. doi: 10.1158/1078-0432.CCR-17-2701
Ahmed, Farzana and Haass, Nikolas K. (2018). Microenvironment-driven dynamic heterogeneity and phenotypic plasticity as a mechanism of melanoma therapy resistance. Frontiers in Oncology, 8 (May) 173, 1-7. doi: 10.3389/fonc.2018.00173
Gallagher, Stuart J., Gunatilake, Dilini, Beaumont, Kimberley A., Sharp, Danae M., Tiffen, Jessamy C., Heinemann, Anja, Weninger, Wolfgang, Haass, Nikolas K., Wilmott, James S., Madore, Jason, Ferguson, Peter M., Rizos, Helen and Hersey, Peter (2018). HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. International Journal of Cancer, 142 (9), 1926-1937. doi: 10.1002/ijc.31199
Vittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K and Simpson, Matthew J (2018). Mathematical models for cell migration with real-time cell cycle dynamics. Biophysical Journal, 114 (5), 1241-1253. doi: 10.1016/j.bpj.2017.12.041
Hammerlindl, Heinz, Ravindran Menon, Dinoop, Hammerlindl, Sabrina, Emran, Abdullah Al, Torrano, Joachim, Sproesser, Katrin, Thakkar, Divya, Xiao, Min, Atkinson, Victoria G., Gabrielli, Brian, Haass, Nikolas K., Herlyn, Meenhard, Krepler, Clemens and Schaider, Helmut (2018). Acetylsalicylic acid governs the effect of sorafenib in RAS- mutant cancers. Clinical Cancer Research, 24 (5), 1090-1102. doi: 10.1158/1078-0432.CCR-16-2118
Kienzle, Arne, Kurch, Sven, Schloder, Janine, Berges, Carsten, Ose, Robert, Schupp, Jonathan, Tuettenberg, Andrea, Weiss, Henning, Schultze, Jennifer, Winzen, Svenja, Schinnerer, Meike, Koynov, Kaloian, Mezger, Markus, Haass, Nikolas K., Tremel, Wolfgang and Jonuleit, Helmut (2017). Dendritic mesoporous silica nanoparticles for pH-stimuli-responsive drug delivery of TNF-alpha. Advanced Healthcare Materials, 6 (13) 1700012, 1700012+. doi: 10.1002/adhm.201700012
Smith, Michael P., Rowling, Emily J., Miskolczi, Zsofia, Ferguson, Jennifer, Spoerri, Loredana, Haass, Nikolas K., Sloss, Olivia, Mcentegart, Sophie, Arozarena, Imanol, von Kriegsheim, Alex, Rodriguez, Javier, Brunton, Holly, Kmarashev, Jivko, Levesque, Mitchell P., Dummer, Reinhard, Frederick, Dennie T., Andrews, Miles C., Cooper, Zachary A., Flaherty, Keith T., Wargo, Jennifer A. and Wellbrock, Claudia (2017). Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure. EMBO Molecular Medicine, 9 (8), 1011-1029. doi: 10.15252/emmm.201607156
Haass, Nikolas K. and Gabrielli, Brian (2017). Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities. Experimental Dermatology, 26 (7), 649-655. doi: 10.1111/exd.13303
Fane, Mitchell E., Chhabra, Yash, Hollingsworth, David E. J., Simmons, Jacinta L., Spoerri, Loredana, Oh, Tae Gyu, Chauhan, Jagat, Chin, Toby, Harris, Lachlan, Harvey, Tracey J., Muscat, George E. O., Goding, Colin R., Sturm, Richard A., Haass, Nikolas K., Boyle, Glen M., Piper, Michael and Smith, Aaron G. (2017). NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF. EBioMedicine, 16, 63-75. doi: 10.1016/j.ebiom.2017.01.013
Maadi, Hamid, Moshtaghian, Abdolvahab, Taha, Masoumeh Fakhr, Mowla, Seyed Javad, Kazeroonian, Asiye, Haass, Nikolas K. and Javeri, Arash (2016). Multimodal tumor suppression by miR-302 cluster in melanoma and colon cancer. International Journal of Biochemistry and Cell Biology, 81 (A), 121-132. doi: 10.1016/j.biocel.2016.11.004
Haass, N. K. (2016). JNK-ERK signalling in melanoma: rewired or entangled?. British Journal of Dermatology, 175 (6), 1139-1140. doi: 10.1111/bjd.14903
Haass, Nikolas K. (2016). Zielgerichtete Melanomtherapie – Die Rolle der dynamischen Tumorheterogenität. Spectrum Dermatologie, 2016 (3), 14-17.
Skalamera, Dubravka, Dahmer-Heath, Mareike, Stevenson, Alexander J., Pinto, Cletus, Shah, Esha T., Daignault, Sheena M., Said, Nur Akmarina B. M., Davis, Melissa, Haass, Nikolas K., Williams, Elizabeth D., Hollier, Brett G., Thompson, Erik W., Gabrielli, Brian and Gonda, Thomas J. (2016). Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer. Oncotarget, 7 (38), 61000-61020. doi: 10.18632/oncotarget.11314
Beaumont, Kimberley A., Hill, David S., Daignault, Sheena M., Lui, Goldie Y. L., Sharp, Danae M., Gabrielli, Brian, Weninger, Wolfgang and Haass, Nikolas K. (2016). Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells. Journal of Investigative Dermatology, 136 (7), 1479-1489. doi: 10.1016/j.jid.2016.02.805
Giles, Keith M., Brown, Rikki A. M., Ganda, Clarissa, Podgorny, Melissa J., Candy, Patrick A., Wintle, Larissa C., Richardson, Kirsty L., Kalinowski, Felicity C., Stuart, Lisa M., Epis, Michael R., Haass, Nikolas K., Herlyn, Meenhard and Leedman, Peter J. (2016). microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB. Oncotarget, 7 (22), 31663-31680. doi: 10.18632/oncotarget.9421
Vaidyanathan, Srividya, Cato, Kathleen, Tang, Lu, Pavey, Sandra, Haass, Nikolas K., Gabrielli, Brian G. and Duijf, Pascal H. G. (2016). In vivo overexpression of Emi1 promotes chromosome instability and tumorigenesis. Oncogene, 35 (41), 5446-5455. doi: 10.1038/onc.2016.94
Beaumont, Kimberley A., Anfosso, Andrea, Ahmed, Farzana, Weninger, Wolfgang and Haass, Nikolas K. (2015). Imaging- and flow cytometry-based analysis of cell position and the cell cycle in 3d melanoma spheroids. Journal of Visualized Experiments, 106 (e53486) e53486, e53486. doi: 10.3791/53486
Ke, Yazi D., van Hummel, Annika, Stevens, Claire H., Gladbach, Amadeus, Ippati, Stefania, Bi, Mian, Lee, Wei S., Kruger, Sarah, van der Hoven, Julia, Volkerling, Alexander, Bongers, Andre, Halliday, Glenda, Haass, Nikolas K., Kiernan, Matthew, Delerue, Fabien and Ittner, Lars M. (2015). Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS. Acta Neuropathologica, 130 (5), 661-678. doi: 10.1007/s00401-015-1486-0
Ravindran Menon, D., Das, S., Krepler, C., Vultur, A., Rinner, B., Schauer, S., Kashofer, K., Wagner, K., Zhang, G., Bonyadi Rad, E., Haass, N. K., Soyer, H. P., Gabrielli, B., Somasundaram, R., Hoefler, G., Herlyn, M. and Schaider, H. (2015). A stress-induced early innate response causes multidrug tolerance in melanoma. Oncogene, 34 (34), 4448-4459. doi: 10.1038/onc.2014.372
Menon, D. Ravindran, Das, S., Krepler, C., Vultur, A., Rinner, B., Schauer, S., Kashofer, K., Wagner, K., Zhang, G., Rad, E. Bonyadi, Haass, N. K., Soyer, H. P., Gabrielli, B., Somasundaram, R., Hoefler, G., Herlyn, M. and Schaider, H. (2015). Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015). Oncogene, 34 (34), 4545-4545. doi: 10.1038/onc.2014.432
Haass, Nikolas K. (2015). Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?. Melanoma Management, 2 (2), 93-95. doi: 10.2217/MMT.15.1
Tikoo, Shweta and Haass, Nikolas K. (2015). Friends or foes: IL-10 and TGF-beta in melanoma. Experimental Dermatology, 24 (4), 254-255. doi: 10.1111/exd.12661
Burke, Michael T., Morais, Christudas, Oliver, Kimberley A., Lambie, Duncan L. J., Gobe, Glenda C., Carroll, Robert P., Staatz, Christine E., Sinnya, Sudipta, Soyer, H. Peter, Winterford, Clay, Haass, Nikolas K., Campbell, Scott B. and Isbel, Nicole M. (2015). Expression of Bcl-xL and Mcl-1 in the Nonmelanoma Skin Cancers of Renal Transplant Recipients. American Journal of Clinical Pathology, 143 (4), 514-526. doi: 10.1309/AJCPQNB5WA3PLQBK
Haass, Nikolas K., Nassif, Najah and McGowan, Eileen M. (2015). Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.. BioMed Research International, 2015 165105, 165105.1-165105.9. doi: 10.1155/2015/165105
Hill, David S., Lovat, Penny E. and Haass, Nikolas K. (2014). Induction of endoplasmic reticulum stress as a strategy for melanoma therapy: is there a future?. Melanoma Management, 1 (2), 127-137. doi: 10.2217/MMT.14.16
Haass, Nikolas K., Beaumont, Kimberley A., Hill, David S., Anfosso, Andrea, Mrass, Paulus, Munoz, Marcia A., Kinjyo, Ichiko and Weninger, Wolfgang (2014). Real-time cell cycle imaging during melanoma growth, invasion, and drug response. Pigment Cell and Melanoma Research, 27 (5), 764-776. doi: 10.1111/pcmr.12274
Wang, Qian, Beaumont, Kimberley A., Otte, Nicholas J., Font, Josep, Bailey, Charles G., van Geldermalsen, Michelle, Sharp, Danae M., Tiffen, Jessamy C., Ryan, Renae M., Jormakka, Mika, Haass, Nikolas K., Rasko, John E. J. and Holst, Jeff (2014). Targeting glutamine transport to suppress melanoma cell growth. International Journal of Cancer, 135 (5), 1060-1071. doi: 10.1002/ijc.28749
Moloney, Fergal J., Guitera, Pascale, Coates, Elliot, Haass, Nikolas K., Ho, Kenneth, Khoury, Ritta, O'Connell, Rachel L., Raudonikis, Leo, Schmid, Helen, Mann, Graham J. and Menzies, Scott W. (2014). Detection of primary melanoma in individuals at extreme high risk: a prospective 5-year follow-up study. JAMA Dermatology, 150 (8), 819-827. doi: 10.1001/jamadermatol.2014.514
Haass, Nikolas K. and Schumacher, Udo (2014). Melanoma never says die. Experimental Dermatology, 23 (7), 471-472. doi: 10.1111/exd.12400
Mohana-Kumaran, Nethia, Hill, David S., Allen, John D. and Haass, Nikolas K. (2014). Targeting the intrinsic apoptosis pathway as a strategy for melanoma therapy. Pigment Cell and Melanoma Research, 27 (4), 525-539. doi: 10.1111/pcmr.12242
Beaumont, Kimberley A., Mohana-Kumaran, Nethia and Haass, Nikolas K. (2013). Modeling Melanoma In Vitro and In Vivo. Healthcare, 2 (1), 27-46. doi: 10.3390/healthcare2010027
Pavey, Sandra, Spoerri, Loredana, Haass, Nikolas K. and Gabrielli, Brian (2013). DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.. Pigment Cell and Melanoma Research, 26 (6), 805-816. doi: 10.1111/pcmr.12136
Tong, P. L., Qin, J., Cooper, C. L., Lowe, P. M., Murrell, D. F., Kossard, S., Ng, L. G., Roediger, B., Weninger, W. and Haass, N. K. (2013). A quantitative approach to histopathological dissection of elastin-related disorders using multiphoton microscopy. British Journal of Dermatology, 169 (4), 869-879. doi: 10.1111/bjd.12430
Stehn, Justine R., Haass, Nikolas K., Bonello, Teresa, Desouza, Melissa, Kottyan, Gregg, Treutlein, Herbert, Zeng, Jun, Nascimento, Paula R. B. B., Sequeira, Vanessa B., Butler, Tanya L., Allanson, Munif, Fath, Thomas, Hill, Timothy A., McCluskey, Adam, Schevzov, Galina, Palmer, Stephen J., Hardeman, Edna C., Winlaw, David, Reeve, Vivienne E., Dixon, Ian, Weninger, Wolfgang, Cripe, Timothy P. and Gunning, Peter W. (2013). A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells. Cancer Research, 73 (16), 5169-5182. doi: 10.1158/0008-5472.CAN-12-4501
Wroblewski, David, Mijatov, Branka, Mohana- Kumaran, Nethia, Lai, Fritz, Gallagher, Stuart J., Haass, Nikolas K., Zhang, Xu Dong and Hersey, Peter (2013). The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance. Carcinogenesis, 34 (2), 237-247. doi: 10.1093/carcin/bgs330
Brandner, Johanna M. and Haass, Nikolas K. (2013). Melanoma's connections to the tumour microenvironment. Pathology, 45 (5), 443-452. doi: 10.1097/PAT.0b013e328363b3bd
Lucas, Keryn M., Mohana-Kumaran, Nethia, Lau, Diana, Zhang, Xu Dong, Hersey, Peter, Huang, David C., Weninger, Wolfgang, Haass, Nikolas K. and Allen, John D. (2012). Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737. Clinical Cancer Research, 18 (3), 783-795. doi: 10.1158/1078-0432.CCR-11-1166
Hersey, P., Smalley, K. S., Weeraratna, A., Bosenberg, M., Zhang, X. D., Haass, N. K., Paton, E., Mann, G., Scolyer, R. A. and Tüting, T. (2011). Meeting report from the 7th International Melanoma Congress, Sydney, November, 2010. Pigment Cell and Melanoma Research, 24 (1), e1-e15. doi: 10.1111/j.1755-148X.2010.00811.x
McGowan, Eileen M., Alling, Nikki, Jackson, Elise A., Yagoub, Daniel, Haass, Nikolas K., Allen, John D. and Martinello-Wilks, Rosetta (2011). Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: Pitfalls of the MTS assay. PLoS ONE, 6 (6) e20623, e20623.1-e20623.8. doi: 10.1371/journal.pone.0020623
De Zwaan, Sally E. and Haass, Nikolas K. (2010). Genetics of basal cell carcinoma. Australasian Journal of Dermatology, 51 (2), 81-92. doi: 10.1111/j.1440-0960.2009.00579.x
Cocciolone, Raymond A., Crotty, Kerry A., Andrews, Lesley, Haass, Nikolas K. and Moloney, Fergal J. (2010). Multiple desmoplastic melanomas in Birt-Hogg-Dubé syndrome and a proposed signaling link between folliculin, the mTOR pathway, and melanoma susceptibility. Archives of Dermatology, 146 (11), 1316-1318. doi: 10.1001/archdermatol.2010.333
Haass, Nikolas K., Ripperger, D., Wladykowski, E., Dawson, P., Gimotty, P. A., Blome, C., Fischer, F., Schmage, P., Moll, I. and Brandner, Johanna M. (2010). Melanoma progression exhibits a significant impact on connexin expression patterns in the epidermal tumor microenvironment. Histochemistry and Cell Biology, 133 (1), 113-124. doi: 10.1007/s00418-009-0654-5
Lee, John T., Li, Ling, Brafford, Patricia A., Van Den Eijnden, Marcia, Halloran, Molly B., Sproesser, Katrin, Haass, Nikolas K., Smalley, Keiran S. M., Tsai, James, Bollag, Gideon and Herlyn, Meenhard (2010). PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas. Pigment Cell and Melanoma Research, 23 (6), 820-827. doi: 10.1111/j.1755-148X.2010.00763.x
Haass, Nikolas K. and Smalley, Keiran S. M. (2009). Melanoma Biomarkers Current Status and Utility in Diagnosis, Prognosis, and Response to Therapy. Molecular Diagnosis and Therapy, 13 (5), 283-296. doi: 10.1007/BF03256334
Santiago-Walker, A., Li, L., Haass, N. K. and Herlyn M. (2009). Melanocytes: From morphology to application. Skin Pharmacology and Physiology, 22 (2), 114-121. doi: 10.1159/000178870
Haass, Nikolas K. (2008). From Xiphophorus to Melanoma - A tribute to Steven Kazianis (1966-2008) - In memoriam. Zebrafish, 5 (2), 91-92. doi: 10.1089/zeb.2008.9992
Tsai, James, Lee, John T., Wang, Weiru, Zhang, Jiazhong, Cho, Hanna, Mamo, Shumeye, Bremer, Ryan, Gillette, Sam, Kong, Jun, Haass, Nikolas K., Sproesser, Katrin, Li, Ling, Smalley, Keiran S. M., Fong, Daniel, Zhu, Yong-Liang, Marimuthu, Adhirai, Nguyen, Hoa, Lam, Billy, Liu, Jennifer, Cheung, Ivana, Rice, Julie, Suzuki, Yoshihisa, Luu, Catherine, Settachatgul, Calvin, Shellooe, Rafe, Cantwell, John, Kim, Sung-Hou, Schlessinger, Joseph, Zhang, Kam Y. J. ... Bollag, Gideon (2008). Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proceedings of the National Academy of Sciences of the United States of America, 105 (8), 3041-3046. doi: 10.1073/pnas.0711741105
Gottschling, Martin, Haass, Nikolas K. and Buchheim, Andreas (2008). Identification of American herring gull Larus smithsonianus and European herring gull L. argentatus. Limicola, 22 (1), 1-29.
Smalley, Keiran S. M., Lioni, Mercedes, Noma, Kazuhiro, Haass, Nikolas K. and Herlyn, Meenhard (2008). In vitro three-dimensional tumor microenvironment models for anticancer drug discovery. Expert Opinion on Drug Discovery, 3 (1), 1-10. doi: 10.1517/17460441.3.1.1
Haass, Nikolas K., Sproesser, Katrin, Nguyen, Thiennga K., Contractor, Rooha, Medina, C. Angelica, Nathanson, Katherine L., Herlyn, Meenhard and Smalley, Keiran S. M. (2008). The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel. Clinical Cancer Research, 14 (1), 230-239. doi: 10.1158/1078-0432.CCR-07-1440
Smalley, K. S. M., Contractor, R., Haass, N. K., Lee, J. T., Nathanson, K. L., Medina, C. A., Flaherty, K. T. and Herlyn, M. (2007). Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels. British Journal of Cancer, 96 (3), 445-449. doi: 10.1038/sj.bjc.6603596
Smalley K.S.M., Contractor R., Haass N.K., Kulp A.N., Atilla-Gokcumen G.E., Williams D.S., Bregman H., Flaherty K.T., Soengas M.S., Meggers E. and Herlyn M. (2007). An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. Cancer Research, 67 (1), 209-217. doi: 10.1158/0008-5472.CAN-06-1538
Wenke A.-K., Kjellman C., Lundgren-Akerlund E., Uhlmann C., Haass N.K., Herlyn M. and Bosserhoff A.K. (2007). Expression of integrin alpha10 is induced in malignant melanoma. Cellular Oncology, 29 (5), 373-386.
Smalley, Keiran S.M., Haass, Nikolas K., Brafford, Patricia A., Lioni, Mercedes, Flaherty, Keith T. and Herlyn, Meenhard (2006). Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Molecular Cancer Therapeutics, 5 (5), 1136-1144. doi: 10.1158/1535-7163.MCT-06-0084
Haass N.K., Wladykowski E., Kief S., Moll I. and Brandner J.M. (2006). Differential induction of connexins 26 and 30 in skin tumors and their adjacent epidermis. Journal of Histochemistry and Cytochemistry, 54 (2), 171-182. doi: 10.1369/jhc.5A6719.2005
Haass, NK and Herlyn, M (2005). Normal human melanocyte homeostasis as a paradigm for understanding melanoma. Journal of Investigative Dermatology Symposium Proceedings, 10 (2), 153-163. doi: 10.1111/j.1087-0024.2005.200407.x
Haass, Nikolas K., Smalley, Keiran S. M. , Li, Ling and Herlyn, Meenhard (2005). Adhesion, migration and communication in melanocytes and melanoma. Pigment Cell Research, 18 (3), 150-159. doi: 10.1111/j.1600-0749.2005.00235.x
Smalley, KSM, Brafford, P, Haass, NK, Brandner, JM, Brown, E and Herlyn, M (2005). Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion. American Journal of Pathology, 166 (5), 1541-1554. doi: 10.1016/S0002-9440(10)62370-X
Haass, Nikolas K., Smalley, Keiran S. M. and Herlyn, Meenhard (2004). The role of altered cell-cell communication in melanoma progression. Journal of Molecular Histology, 35 (3), 309-318. doi: 10.1023/B:HIJO.0000032362.35354.bb
Pfohler, C, Cree, IA, Ugurel, S, Kuwert, C, Haass, N, Neuber, K, Hengge, U, Corrie, PG, Zutt, M, Tilgen, W and Reinhold, U (2003). Treosulfan and gemcitabine in metastatic uveal melanoma patients: results of a multicenter feasibility study. Anti-Cancer Drugs, 14 (5), 337-340. doi: 10.1097/01.car.0000070764.25457.ca
Windoffer, Reinhard, Borchert-Stuhltrager, Monika, Haass, Nikolas K., Thomas, Sabine, Hergt, Michaela, Bulitta, Clemens J. and Leube, R. E. (1999). Tissue expression of the vesicle protein pantophysin. Cell and Tissue Research, 296 (3), 499-510. doi: 10.1007/s004410051310
Haass, N. K., Kartenbeck, J. and Leube, R. E. (1996). Pantophysin is a ubiquitously expressed synaptophysin homologue and defines constitutive transport vesicles. Journal of Cell Biology, 134 (3), 731-746. doi: 10.1083/jcb.134.3.731
Conference Papers
Kangachar, S. Asgharzadeh, Ahmed, F., Al Emran, A., Boyle, G., Spoerri, L., Schaider, H. and Haass, N.K. (2024). Environmentally stressed drug-naïve melanoma cell subpopulations share a molecular signature with drug-induced early persister cells. Society for Investigative Dermatology (SID) 2024 Meeting, Dallas, TX United States, 15-18 May 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2024.06.641
Kangachar, S. Asgharzadeh, Ahmed, F., Al Emran, A., Boyle, G., Spoerri, L., Schaider, H. and Haass, N. K. (2024). Environmentally stressed drug-naive melanoma cell subpopulations share a molecular signature with drug-induced early persister cells. Society for Investigative Dermatology (SID) 2024 Meeting, Dallas, TX, United States, 15-18 May 2024. Oxford, United Kingdom: Elsevier.
Guan, Yimeng, Robitaille, Melanie, Torrano, Joachim, Haass, Nikolas, Roberts-Thomson, Sarah, Monteith, Gregory and Schaider, Helmut (2024). A calcium influx pathway regulates adaptive melanoma drug tolerance. ASDR 2024 Annual Scientific Meeting, Sydney, NSW Australia, 18-20 July 2024.
Ju, R. J., Falconer, A. D., Dean, K. M., Fiolka, R. P., Sester, D. P., Nobis, M., Timpson, P., Lomakin, A. J., Danuser, G., White, M. D., Oelz, D. B., Haass, N. K. and Stehbens, S. J. (2024). Uncovering Microtubule-driven Mechanisms of Melanoma Invasion. 50th Annual Meeting of the Dermatological Research Working Group (ADF), Dusseldorf, Germany, 6-9 March 2024. Chichester, West Sussex United Kingdom: Wiley-Blackwell.
Torrano, J., Ravindran-Menon, D., Hammerlindl, H., Hammerlindl, S., Emran, A.A., Bordag, N., Zuegner, E., Haass, N.K., Sadowski, M., Stow, J., Magnes, C., Fujita, M. and Schaider, H. (2023). 1244 Epigenetic and metabolic vulnerabilities of adaptive drug resistance to targeted therapies in melanoma. 1st International Societies for Investigative Dermatology Meeting (ISID 2023), Tokyo, Japan, 10-13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.1258
Guan, Y., Griffiths, L., Gunasingh, G., Kumar, J., Spoerri, L. and Haass, N.K. (2023). 1255 Modulating phenotypic melanoma heterogeneity and immune cell infiltration. 1st International Societies for Investigative Dermatology Meeting (ISID 2023), Tokyo, Japan, 10-13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.1269
Ju, R. J., Chhabra, Y., Stehbens, S. J. and Haass, N. (2023). Uncovering biomechanically regulated cellular processes of melanoma cell invasion and survival in confined environments. Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Berlin, Germany, 11-14 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.
Spoerri, L., Tonnessen-Murray, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Gunasingh, G., Vanwalleghem, G., Daignault, S., Fane, M. E., Schaider, H., Smith, A., Stehbens, S. J., Weninger, W., Scott, E. E., Gabrielli, B. and Haass, N. (2023). MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma. Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Berlin, Germany, 11-14 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.
Daignault, S., Ju, R. J., Spoerri, L., Stehbens, S. J., Hill, D. S., Dolcetti, R. and Haass, N. (2023). Bortezomib induces immunogenic cell death in melanoma and enhances immune response in vivo. Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Berlin, Germany, 11-14 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.
Spoerri, L., Tonnessen-Murray, Ca, Beaumont, K. A., Hill, D., Jurek, R., Gunasingh, G., Weninger, W. and Haass, N. K. (2020). MITF-mediated changes of tumor architecture, tensile stress and extracellular matrix control intratumor heterogeneity in melanoma. Virtual Conference of the Society for Investigative Dermatology (SID ), Online, 13-16 May 2020. New York, NY, United States: Elsevier.
Henser-Brownhill, Tristan, Ju, Robert J., Haass, Nikolas K., Stehbens, Samantha J., Ballestrem, Christoph and Cootes, Timothy F. (2020). Estimation of cell cycle states of human melanoma cells with quantitative phase imaging and deep learning. 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), Iowa City, IA United States, 3-7 April 2020. Piscataway, NJ United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/isbi45749.2020.9098458
Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Smith, A., Scott, E., Schaider, H., Gabrielli, B., Weninger, W. and Haass, N. (2019). Microphthalmia-associated transcription factor regulates dynamic heterogeneity and structural integrity in melanoma. 46th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Munich, Germany, 13-16 March, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.13859
Ju, R. J., Chhabra, Y., Haass, N. and Stehbens, S. J. (2019). Uncovering microtubule-driven mechanisms of melanoma invasion. 46th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Munich Germany, Mar 13-16, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.
Guo, D., Lui, G. Y., Wilmott, J. S., Tikoo, S., Brown, D. L., Mann, G. J., Scolyer, R. A., Stow, J. L., Weninger, W., Beaumont, K. A. and Haass, N. (2019). RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. 46th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Munich, GERMANY, MAR 13-16, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.
Li, D., Ryu, E., Saeidian, A. H., Youssefian, L., Duvall, E., Oliphant, E., Terry, S., Haass, N. K., Uitto, J. and Li, Q. (2019). GGCX mutations in a patient with co-existent overlapping PXE/CL phenotype and thalassemia minor. Society for Investigative Dermatology (SID) Meeting, Chicago, IL United States, 8-11 May 2019. New York, NY United States: Elsevier.
Daignault, S. M., Ju, R. J., Spoerri, L., Stehbens, S. J., Dolcetti, R. and Haass, N. K. (2019). Bortezomib induces immunogenic cell death in melanoma and enhances immune responses in vivo. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.506
Oo, Zay Yar, Proctor, Martina, Stevenson, Alex, Nazareth, Deborah, Larsen, Jill, Haass, Nikolas and Gabrielli, Brian G. (2019). Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo. AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology, Atlanta Ga, Mar 29-Apr 03, 2019. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2019-1236
Spoerri, L., Tonnessen, C., Beaumont, K., Hill, D., Jurek, R., Gunasingh, G., Daignault, S. M., Vanwalleghem, G., Weninger, W., Scott, E. and Haass, N. K. (2019). MITF-mediated extracellular matrix changes control intratumour heterogeneity in melanoma. 49th Annual ESDR Meeting, Bordeaux, France, 18-21 September 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.709
Daignault, S. M., Spoerri, L., Ju, R. J., Stehbens, S. J., Hill, D. S., Dolcetti, R. and Haass, N. (2019). Enforcing cellular stress promotes apoptotic and immunogenic responses in melanoma. 46th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Munich, Germany, 13-16 March 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1111/exd.13859
Daignault, S. M., Ju, R., Spoerri, L., Stehbens, S. J., Hill, D. S., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2019). Bortezomib-induced immunogenic cell death enhances immune response in melanoma. Society for Investigative Dermatology (SID) Meeting, Chicago, IL United States, 8-11 May 2019. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2019.03.907
Oo, Z. U., Proctor, M., Stevenson, A., Nazareth, D., Haass, N., Larsen, J. and Gabrielli, B. (2018). Less is more: subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors in vitro and in vivo. 30th EORTC-NCI-AACR Symposium, Dublin Ireland, Nov 13-16, 2018. OXFORD: ELSEVIER SCI LTD.
Guo, Dajiang, Lui, Goldie Y., Sharp, Danae M., Lai, Siew Li, Tikoo, Shweta, Kwan, Rain, van Geldermalsen, Michelle, Holst, Jeff, Haass, Nikolas K., Weninger, Wolfgang and Beaumont, Kimberley A. (2018). Rab27a promotes melanoma cell invasion and metastasis via the regulation of exosome secretion. Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago Il, Apr 14-18, 2018. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2018-5167
Guo, D., Lui, G. Y., Tikoo, S., Weninger, W., Beaumont, K. A. and Haass, N. K. (2018). High Rab27a expression is associated with poor melanoma prognosis and promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. International Investigative Dermatology (IID) Meeting, Orlando Fl, May 16-19, 2018. NEW YORK: ELSEVIER SCIENCE INC.
Duijf, Pascal H. G., Vaidyanathan, Srividya, Cato, Kathleen, Thangavelu, Pulari U., Lin, Cheng-Yu, Tang, Lu, Pavey, Sandra, Haass, Nikolas K. and Gabrielli, Brian G. (2018). Overexpression of the cell cycle regulator Emi1 promotes chromosome instability and tumorigenesis. 76th Annual Meeting of the Japanese Cancer Association, Yokohama, Japan, 28-30 September 2017. Tokyo, Japan: Wiley Japan. doi: 10.1111/cas.13499
Guo, D., Lui, G. Y., Weninger, W., Beaumont, K. A. and Haass, N. K. (2018). Rab27a, a novel marker for melanoma metastasis and poor prognosis. Australasian College of Dermatologists, 51st Annual Scientific Meeting, Gold Coast, QLD, Australia, 19-22 May 2018. Hoboken, NJ, United States: Wiley.
Emran, A., Chowdhury, B. R., Hammerlindl, H., Ahmed, F., Haass, N. K., Schuehly, W. and Schaider, H. (2018). Magnolol induces cell death through PI3K/Akt mediated epigenetic modifications boosting targeted inhibition in BRAF and NRAS mutant melanoma. Australasian College of Dermatologists, 51st Annual Scientific Meeting, Gold Coast, QLD, Australia, 19-22 May 2018. Hoboken, NJ, United States: Wiley.
Menon, D. Ravindran, Hammerlindl, H., Emran, A., Torrano, J., Hammerlindl, S., Zhang, G., Krause, L., Somasundaram, R., Sturm, R., Haass, N. K., Flaherty, K., Herlyn, M. and Schaider, H. (2018). Escape form adaptive drug tolerance through OGT and TET1 mediated H3K4me3 remodeling in MAPKi-resistant melanoma. International Investigative Dermatology (IID) Meeting, Orlando, Fl, United States, 16-19 May 2018. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2018.03.1252
Daignault, S. M., Hill, D. S., Spoerri, L., Stehbens, S., Weninger, W., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2018). Targeting cell cycle phase-specific drug sensitivity for melanoma therapy. 45th Annual Meeting of the Arbeitsgemeinscha-Dermatologische-Forschung (ADF), Zurich, Switzerland, 7-10 March 2018. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.
Menon, Dinoop Ravindran, Hammerlindl, Heinz, Al Emran, Abdullah, Torrano, Joachim, Hammerlindl, Sabrina, Zhang, Gao, Somasundaram, Rajasekharan, Sturm, Richard A., Haass, Nikolas K., Flaherty, Keith, Herlyn, Meenhard and Schaider, Helmut (2018). Escape form adaptive drug tolerance through OGT and TET1 mediated H3K4me3 remodeling in MAPKi resistant melanoma. Annual Meeting of the American Association for Cancer Research (AACR), Chicago, IL United States, 14-18 April 2018. Philadelphia, PA United States: American Association of Cancer Research. doi: 10.1158/1538-7445.AM2018-5833
Haass, N. K., Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Daignault, S. M., Ahmed, F., Smith, A. G. and Weninger, W. (2017). Microphthalmia-associated transcription factor regulates dynamic melanoma heterogeneity. 47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR), Salzburg, Austria, 27-30 September 2017. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2017.07.726
Haass, N., Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Daignault, S. M., Gabrielli, B. and Weninger, W. (2017). Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities. Australasian College of Dermatologists 50th Annual Scientific Meeting, International Convention Centre, Sydney, NSW Australia, 6-9 May 2017. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.20_12652
Stehn, J. R., Stevenson, A., Spoerri, L., Daignault, S. M., Gabrielli, B., Eiffe, E., Gunning, P. W. and Haass, N. (2016). Developing a new melanoma drug. HOBOKEN: WILEY-BLACKWELL.
Beaumont, K., Hill, D., Daignault, S., Sharp, D., Gabrielli, B., Weninger, W. and Haass, N. (2016). Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells. Annual Meeting of the Society-for-Investigative-Dermatology (SID), Scottsdale, AZ, United States, 11-14 May 2016. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2016.02.695
Hill, D. S., Beaumont, K. A., Daignault, S. M., Sharp, D. M., Gabrielli, B., Weninger, W. and Haass, N. K. (2016). Cell cycle phase determines efficacy of bortezomib, temozolomide and MAPK inhibitor-induced apoptosis in melanoma. 43rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung-e-V (ADF), Vienna Austria, Mar 10-12, 2016. HOBOKEN: WILEY-BLACKWELL.
Kienzle, A., McGowan, E., Douglas, G., Kaczorowski, D., Weninger, W. and Haass, N. K. (2016). Real-time cell cycle and cell death imaging of the effect of sphingosine kinase inhibition on 3D melanoma spheroids. 43rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung-e-V (ADF), Vienna Austria, Mar 10-12, 2016. HOBOKEN: WILEY-BLACKWELL.
Tonnessen, C. A., Beaumont, K. A., Spoerri, L., Hill, D. S., Jurek, R. J., Daignault, S. M., Ahmed, F., Fane, M., Smith, A., Weninger, W. and Haass, N. K. (2016). MITF regulates cell adhesion and subcompartment-specific distribution of differentially cycling melanoma cells. 43rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung-e-V (ADF), Vienna Austria, Mar 10-12, 2016. HOBOKEN: WILEY-BLACKWELL.
Schaider, H., Menon, D. R., Emran, A., Gabrielli, B., Haass, N., Somasundaram, R. and Herlyn, M. (2016). Stress induced multi-drug tolerance precedes acquired drug resistance in melanoma. 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Barcelona Spain, 18-21 November 2014. Richmond, VIC Australia: Wiley-Blackwell .
Haass, N. K., Lui, G. Y., Sharp, D. M., Tan, S. -Y., Weninger, W. and Beaumont, K. A. (2016). Rab27a regulates invadopodia activity and invasion in melanoma. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
Daignault, S. M., Tonnessen, C. A., Ahmed, F., Spoerri, L. and Haass, N. K. (2016). MITF modifies invasion and characteristics of the epithelial to mesenchymal transition in melanoma. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
Nierfeld, M., Nascimento, P. R., Baesler, K., Knuever, J., Spoerri, L., Schaider, H., Weninger, W. and Haass, N. K. (2016). Rose Bengal melanoma therapy - phototoxicity versus intrinsic cytotoxicity. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.
Vaidyanathan, S., Cato, K., Tang, L., Pavey, S., Haass, N. K., Gabrielli, B. G. and Duijf, P. H. G. (2016). Overexpression of Early Mitotic Inhibitor 1 (Emi1) promotes genomic instability and cancer. Annual Meeting of the American Society for Cell Biology (ASCB), San Francisco Ca, Dec 03-07, 2016. BETHESDA: American Society for Cell Biology.
Ahmed, F., Tonnessen, C., Spoerri, L., Daignault, S., Stark, M., Schaider, H., Hill, M. and Haass, N. (2016). Identification of unique molecular signatures of differentially cycling tumour cell subpopulations in a 3D melanoma model. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12584
Tonnessen, Crystal A., Beaumont, Kimberley A., Hill, David S., Daignault, Sheena M., Anfosso, Andrea, Jurek, Russell J., Weninger, Wolfgang and Haass, Nikolas K. (2015). MITF regulates proliferative subpopulation tumor architecture and modifies invasion and characteristics of the epithelial to mesenchymal transition within melanoma. 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, United States, 18-22 April 2015. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2015-1420
Menon, Dinoop Ravindran, Das, Suman, Krepler, Clemens, Vultur, Adina, Zhang, Gao, Haass, Nikolas, Soyer, Peter H., Gabrielli, Brian, Somasundaram, Rajasekharan, Hoefler, Gerald, Herlyn, Meenhard and Schaider, Helmut (2015). An early innate stress response precedes acquired drug resistance in melanoma. 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia Pa United States, April 18-22, 2015. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2015-2684
Hill, D. S., Beaumont, K. A., Daignault, S. M., Anfosso, A., Sharp, D. M., Gabrielli, B., Lovat, P. E., Weninger, W. and Haass, N. K. (2015). Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity. 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Ulm, Germany, Mar 05-07, 2015. Chichester, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.12623
Hill, D. S., Beaumont, K. A., Daignault, S. M., Anfosso, A., Lovat, P. E., Weninger, W. and Haass, N. K. (2015). Making stressed melanoma self-destruct. Australasian College of Dermatologists 48th Annual Scientific Meeting, Adelaide, Australia, 16 May, 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12337
Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Anfosso, A., Daignault, S. M., Fane, M., Jurek, R. J., Smith, A. G., Weninger, W. and Haass, N. K. (2015). Melanoma tumor sub-populations are defined by MITF expression, and exhibit enhanced proliferation and characteristics of an EMT. 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Ulm, Germany, 05-07 March 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.12623
Beaumont, K. A., Sharp, D. M., Weninger, W. and Haass, N. K. (2015). Targeting Rab27a to suppress melanoma proliferation and invasion. 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Ulm, Germany, 05-07 March 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.12623
Nascimento, P. R. B. B., Baesler, K., Knuever, J., Douglas, G., Anfosso, A., Weninger, W. and Haass, N. K. (2014). Rose Bengal melanoma therapy: Phototoxicity versus intrinsic cytotoxicity. The Australasian College of Dermatologists 47th Annual Scientific Meeting, Melbourne, VIC Australia, 18-21 May 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12174
Haass, N. K., Beaumont, K., Anfosso, A., Hill, D., Jurek, R., Sharp, D., Mrass, P., Munoz, M., Kinjyo, I. and Weninger, W. (2014). Defining the mode of melanoma's proliferative heterogeneity by real-time cell cycle imaging. 41st Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Cologne, Germany, 13-15 March 2014. West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.12314
Mohana-Kumaran, N., Lucas, K. M., Roediger, B., Scolyer, R. A., Weninger, W., Allen, J. D. and Haass, N. K. (2013). Loss of Noxa and Puma have inverse effects on melanomagenesis in a predisposed, genetically-defined mouse melanoma model. International Investigative Dermatology Meeting, Edinburgh Scotland, May 08-11, 2013. NEW YORK: NATURE PUBLISHING GROUP.
Haass, N. K., Beaumont, K. A., Anfosso, A., Hill, D. S., Jurek, R. K., Mrass, P., Munoz, M., Kinjyo, I., Miyawaki, A. and Weninger, W. (2013). MITF regulates the proliferative architecture of the melanoma microenvironment. International Investigative Dermatology Meeting, Edinburgh Scotland, May 08-11, 2013. NEW YORK: NATURE PUBLISHING GROUP.
Beaumont, K. A., Anfosso, A., Hill, D. S., Jurek, R. J., Mrass, P., Munoz, M. M., Kinjyo, I., Miyawaki, A., Weninger, W. and Haass, N. K. (2013). Cancer cells and galaxies - novel image analysis techniques identify subcompartment-specific cell cycle dynamics and motility in melanoma. 40th Annual Meeting of the Association-of-Dermatological-Research, Dessau Germany, Mar 14-16, 2013. HOBOKEN: WILEY-BLACKWELL.
Pandjaitan, M. A. T., Bohner, C., Zorn-Kruppa, M., Vidal-y-Sy, S., Haass, N. K., Moll, I and Brandner, J. M. (2013). ZO-1 kontrolliert die Invasivität von Melanomzellen. 23. Deutscher Hautkrebskongress 2013 und ADO-Jahrestagung, Essen, 26 - 28 September 2013. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/ddg.12189
Haass, N. (2013). BRAF New World. 46th Annual Scientific Meeting, Sydney, New South Wales, 19 – 22 May 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12051
Hill, D., Beaumont, K., Anfosso, A., Miyawaki, A., Weninger, W., Lovat, P. and Haass, N. (2013). Induction of Endoplasmic Reticulum Stress as a Strategy for Melanoma Therapy. 8th World Congress of Melanoma, 9th Congress of the European Association of Dermatology (EADO), 7th Interdisciplinary Melanoma/Skin Cancer Meeting, 3rd European Post-Chicago Melanoma Meeting 2013, Hamburg, German, 77 - 20 July 2013. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/ddg.12162
Nascimento, P., Baesler, K., Knuever, J., Douglas, G., Anfosso, A., Weninger, W. and Haass, N. (2013). Rose Bengal - Phototoxicity versus Intrinsic Cytotoxicity. 8th World Congress of Melanoma, 9th Congress of the European Association of Dermatology (EADO), 7th Interdisciplinary Melanoma/Skin Cancer Meeting, 3rd European Post-Chicago Melanoma Meeting 2013, Hamburg, Germany, 17 - 20 July 2013. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/ddg.12160
Haass, N., Beaumont, K., Anfosso, A., Hill, D., Jurek, R., Mrass, P., Munoz, M., Kinjyo, I., Miyawaki, A. and Weninger, W. (2013). The Microphthalmia-Associated Transcription Factor (MITF) Regulates the Proliferative Architecture of the Melanoma Microenvironment. 8th World Congress of Melanoma, 9th Congress of the European Association of Dermatology (EADO), 7th Interdisciplinary Melanoma/Skin Cancer Meeting, 3rd European Post-Chicago Melanoma Meeting 2013, Hamburg, Germany, 17 - 20 July 2013. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/ddg.12161
Beaumont, K. A., Weninger, W. and Haass, N. K. (2012). Rab27A Regulates Melanoma Proliferation and Invasion. WILEY-BLACKWELL.
Hill, D. S., Anfosso, A., Kinjyo, I., Lovat, P. E., Kanagawa, O. and Haass, N. K. (2012). Optimization of Endoplasmic Reticulum (Er) Stress-Inducing Therapies for Melanoma Using Real-Time Cell Cycle Imaging. 58th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Nov 02-06, 2007. JOHN WILEY & SONS INC.
Moloney, F., Guitera, P., Coates, E., Haass, N., Ho, K., Khoury, R., Mann, G. and Menzies, S. (2012). Sequential digital dermoscopic imaging and total body photography aid detection of primary melanoma in individuals at high risk: a prospective 5-year follow-up study. 92nd Annual Meeting of the British-Association-of-Dermatologists, Birmingham England, Jul 03-05, 2012. WILEY-BLACKWELL. doi: 10.1111/j.1365-2133.2012.10976.x
Hersey, Peter, Wroblewski, David, Mijatov, Branka, Zhang, Xu Dong and Haass, Nikolas (2012). Effect of the BH3 mimetic ABT-737 on human melanoma cells to apoptosis induced by selective BRAF inhibitors.. 48th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 01-06, 2012. AMER SOC CLINICAL ONCOLOGY.
Haass, N. K., Anfosso, A., Beaumont, K. A., Hill, D. S., Mrass, P., Kinjyo, I., Kanagawa, O. and Weninger, W. (2012). MITF-driven subcompartment-specific distribution of differentially cycling tumor cells in melanoma. 75th Annual Meeting of the Society-for-Investigative-Dermatology, Raleigh Nc, May 09-12, 2012. NATURE PUBLISHING GROUP.
Moloney, F. J., Guitera, P., Coates, E., Haass, N., Ho, K., Khoury, R., Mann, G. and Menzies, S. W. (2012). Observation of a five year high risk clinic for primary melanoma. WILEY-BLACKWELL.
Coates, E., Moloney, F. J., Guitera, P., Haass, N., Ho, K., Khoury, R., Mann, G. and Menzies, S. W. (2012). Melanoma detection in high risk patients: A case series. WILEY-BLACKWELL.
Stehn, J. R., Haass, N. K., Bonello, T., Desouza, M., Kottyan, G., Treutlein, H., Zeng, J., Nascimento, P. R., Butler, T., Allanson, M., Fath, T., Hill, T. A., McCluskey, A., Schevzov, G., Palmer, S., Hardeman, E. C., Winlaw, D., Reeve, V. E., Dixon, I., Weninger, W., Cripe, T. P. and Gunning, P. (2012). Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells. 39th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Marburg Germany, Mar 01-03, 2012. WILEY-BLACKWELL.
Haass, N. K., Anfosso, A., Beaumont, K. A., Hill, D. S., Mrass, P., Kinjyo, I., Kanagawa, O. and Weninger, W. (2012). The subcompartment-specific distribution of differentially cycling tumor cells in melanoma is regulated by MITF. 39th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Marburg Germany, Mar 01-03, 2012. WILEY-BLACKWELL.
Bohner, C., Pandjaitan, M. A., Haass, N. K., Zorn-Kruppa, M., Moll, I., von den Driesch, P., Schaider, H. and Brandner, J. M. (2012). The role(s) of the junction protein ZO-1 in malignant melanoma. 39th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Marburg Germany, Mar 01-03, 2012. WILEY-BLACKWELL.
Smalley, Keiran S. M., Aplin, Andrew E., Flaherty, Keith T., Hoeller, Christoph, Bosserhoff, Anja K., Haass, Nikolas K., Bosenberg, Marcus, Ribas, Antoni, Barnhill, Raymond, Kudchadkar, Ragini and Messina, Jane L. (2012). Meeting report from the 2011 international melanoma congress, Tampa, Florida. Malden, MA, United States: Wiley-Blackwell Publishing. doi: 10.1111/j.1755-148X.2011.00943.x
Haass, N. K., Anfosso, A., Kinjyo, I., Kanagawa, O. and Weninger, W. (2011). Real-time cell cycle imaging: Melanomas are composed of differentially cycling tumor cells in a subcompartment-specific distribution. Annual Meeting of the Society-for-Investigative-Dermatology, Phoenix Az, May 04-07, 2011. NATURE PUBLISHING GROUP.
Nascimento, P. R., Knuever, J., Weninger, W. and Haass, N. (2011). Utilization of the auto fluorescent drug Rose Bengal as a novel approach for the investigation of drug effects within solid tumors in 3D culture and in vivo. 38th Annual Meeting of the Arbeitsgemeinschaft-Dermatologishche-Forschung, Tuebingen Germany, Feb 17-19, 2011. WILEY-BLACKWELL PUBLISHING, INC.
Haass, N., Anfosso, A., Kinjyo, I., Kanagawa, O. and Weninger, W. (2011). Real-time imaging of cell cycle progression in melanoma. 38th Annual Meeting of the Arbeitsgemeinschaft-Dermatologishche-Forschung, Tuebingen Germany, Feb 17-19, 2011. WILEY-BLACKWELL PUBLISHING, INC.
Bohner, C., Haass, N. K., Vidal-y-Sy, S., Moll, I., von den Driesch, P., Schaider, H. and Brandner, J. (2011). Differential expression of ZO-1 in melanoma and nevi and their tumor microenvironment - an indicator of malignancy. 38th Annual Meeting of the Arbeitsgemeinschaft-Dermatologishche-Forschung, Tuebingen Germany, Feb 17-19, 2011. WILEY-BLACKWELL PUBLISHING, INC.
Bohner, C., Haass, N. K., Moll, I, von den Driesch, P., Schaider, H. and Brandner, J. M. (2011). Different ZO-1 Localization in Melanoma, Nevi and their Tumor-Microenvironment - An Indicator of Malignancy. 46. Tagung der Deutschen Dermatologischen Gesellschaft Vereinigung Deutschsprachiger Dermatologen e. V., Dresden, Germany, 30 March - 2 April 2011. Berlin, Germany: Wiley-Blackwell Verlag GmbH. doi: 10.1111/j.1610-0387.2011.07632.x
Stehn, J., Schevzov, G., Bonello, T., McCluskey, A., Haass, N., Palmer, S., Hardeman, E., Allanson, M., Reeve, V. and Gunning, P. (2010). Tropomyosin Tm5NM1: A novel target for cancer therapy. 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Berlin Germany, Nov 16-19, 2010. PERGAMON-ELSEVIER SCIENCE LTD. doi: 10.1016/S1359-6349(10)72041-3
Douglas, G., Kaczorowski, D., McGowan, E., Anfosso, A., Xia, P., Weninger, W. and Haass, N. K. (2010). Modification of the sphingosine kinase pathway as a novel therapeutic approach for melanoma. 37th Annual Meeting of the Arbeitsgemeinschaft-Dermatologishche-Forschung, Luebeck Germany, Feb 18-20, 2010. ELSEVIER GMBH, URBAN & FISCHER VERLAG.
Mohana-Kumaran, N., Lucas, K. M., Weninger, W., Allen, J. D. and Haass, N. K. (2009). NOXA inhibits melanoma growth and invasion in 3D models. 5th Annual Scientific Meeting of the Australasian-Society-for-Dermatology-Research, Sydney Australia, May 21-22, 2008. NATURE PUBLISHING GROUP.
Haass, N. K., Ripperger, D., Wladykowski, E., Dawson, P., Gimotty, P. A., Reich, C., Fischer, F., Schmage, P., Moll, I. and Brandner, J. M. (2009). Connexin expression patterns in the epidermal tumour microenvironment of melanoma are valuable biomarkers for diagnosis and prognosis. 5th Annual Scientific Meeting of the Australasian-Society-for-Dermatology-Research, Sydney Australia, May 21-22, 2008. NATURE PUBLISHING GROUP.
Haass, Nikolas K., Sproesser, Katrin, Nguyen, Thiennga K., Contractor, Rooha, Herlyn, Meenhard and Smalley, Keiran S. M. (2009). Inhibition of MEK with AZD6244 is cytostatic as a monotherapy in melanoma, but cytotoxic when combined with docetaxel leading to tumour regression in vitro and in vivo. 5th Annual Scientific Meeting of the Australasian-Society-for-Dermatology-Research, Sydney Australia, May 21-22, 2008. NATURE PUBLISHING GROUP.
Fuchs, F., Moll, I, Haass, N. K., Houdek, P., Wladykowski, E. and Brandner, J. M. (2009). Tight junction proteine in merkel cell carcinoma. MALDEN: WILEY-BLACKWELL PUBLISHING, INC.
Haass, N. K., Smalley, K. S., Lee, J. T., Weninger, W. and Herlyn, M. (2009). Novel small molecule kinase inhibitors with potent and specific anti-melanoma activity. 69th Annual Meeting of the Society-of-Investigative-Dermatology, Montreal Canada, May 06-09, 2009. NATURE PUBLISHING GROUP.
Haass, N. K., Smalley, K. S., Lee, J. T. and Herlyn, M. (2009). Targeted therapy of melanoma: Novel kinase inhibitors with potent and specific anti-melanoma activity. 36th Annual Meeting of the Arbeitsgemeinschaft-Dermatologishche-Forschung, Heidelberg Germany, Mar 05-07, 2009. WILEY-BLACKWELL.
Bohner, C., Haass, N. K., Ripperger, D., Wladykowski, E., Moll, I. and Brandner, J. (2009). ZO-1 in malignant melanoma and adjacent epidermis. 36th Annual Meeting of the Arbeitsgemeinschaft-Dermatologishche-Forschung, Heidelberg Germany, Mar 05-07, 2009. WILEY-BLACKWELL.
Haass, N. K., Ripperger, D., Wladykowski, E., Fischer, F., Schmage, P., Moll, I. and Brandner, J. M. (2009). Usability of Connexin 26, 30 and 43 as markers for diagnosis and prognosis of malignant melanoma. 36th Annual Meeting of the Arbeitsgemeinschaft-Dermatologishche-Forschung, Heidelberg Germany, Mar 05-07, 2009. WILEY-BLACKWELL.
Artis, Dean R., Tsai, James, Bremer, Ryan, Zhang, Jiazhong, Cho, Hanna, Mamo, Shumeye, Spevak, Wayne, Gillette, Samuel, Kong, Jun, Fong, Daniel, Zhu, Yong-Liang, Wang, Weiru, Nespi, M., Marimuthu, Adhirai, Lam, Billy, Shi, Shenghua, Burton, Betsy, Guan, Yinghui, Liu, Jennifer, Cheung, Ivana, Rice, Julie, Wong, Bernice, Nguyen, Hoa, Suzuki, Yoshihisa, Luu, Catherine, Settachatgul, Calvin, Shellooe, Rafe, Cantwell, John, Haass, Nikolas K. ... Bollag, Gideon (2008). COMP 374-Potent inhibitors of mutant-B-Raf and Fms kinases designed using a scaffold-based drug discovery approach. 236th National Meeting of the American-Chemical-Society, Philadelphia Pa, Aug 17-21, 2008. AMER CHEMICAL SOC.
Ripperger, D., Haass, N. K., Wladykowski, E., Fischer, F., Schmage, P., Moll, I. and Brandner, I. M. (2008). Vertical and horizontal expression of Cx26 in epidermis adjacent to malignant melanoma correlates to tumor depth. International Investigative Dermatology Meeting, Kyoto Japan, May 14-17, 2008. NATURE PUBLISHING GROUP.
Ripperger, D., Wladykowski, E., Haass, N. K., Fischer, F., Moll, I. and Brandner, J. M. (2008). Tumour depth influences vertical and horizontal expression of Cx26 in epidermis adjacent to malignant melanoma. 35th Annual Meeting of the Arbeitsgemeinschaft-Dermatolog-Forschung, Eriangen Germany, Feb 28-Mar 01, 2008. BLACKWELL PUBLISHING.
Haass, N. K., Smalley, K. S., Sproesser, K., Contractor, R. and Herlyn, M. (2007). The novel MEK1/2 inhibitor AZD6244 (ARRY-142886) inhibits the growth of melanomas harboring the BRAF V600E mutation in vitro and in vivo. 68th Annual Meeting of the Society-for-Investigative-Dermatology, Los Angeles Ca, May 09-12, 2007. NATURE PUBLISHING GROUP.
Haass, N. K., Smalley, K. S. and Herlyn, M. (2006). The microenvironment is the key determinant of melanoma drug resistance. 67th Annual Meeting of the Society-for-Investigative-Dermatology, Philadelphia Pa, May 03-06, 2006. NATURE PUBLISHING GROUP.
Haass, N, Brandner, J, Brafford, P, Wladykowski, E, Kazianis, S, Moll, I and Herlyn, M (2005). Differential gap junctional intercellular communication between melanoma cells and cells in their microenvironment. 35th Annual Meeting of the European-Society-for-Dermatological-Research, Tubingen Germany, Sep 22-24, 2005. BLACKWELL PUBLISHING.
Haass, NK, Wladykowski, E, Kief, S, Moll, I and Brandner, JM (2004). Connexins 26 and 43 are differentially induced in skin tumors and the adjacent epidermis. 34th Annual Meeting of the European-Society-for-Dermatological-Research, Vienna Austria, Sep 09-11, 2004. BLACKWELL PUBLISHING INC.
Haass, NK, Brandner, JM, Brafford, PA, Wladykowski, E, Kazianis, S, Smalley, KS, Moll, I and Herlyn, M (2004). Connexins are differentially expressed in melanoma and adjacent epidermis. 65th Annual Meeting of the Society-for-Investigative-Dermatology, Providence Ri, Apr 28-May 01, 2004. BLACKWELL PUBLISHING INC.
Haass, NK, Brandner, JM, Wladykowski, E, von den Driesch, P, Kief, S, Houdek, P and Moll, I (2002). Induction of connexins Cx30 and Cx26 in epidermis adjacent to malignant melanoma but not to melanocytic nevi. BLACKWELL PUBLISHING INC.
Pfohler, C, Ugurel, S, Cree, IA, Plowman, N, Kuwert, C, Neuber, K, Haass, N, Tilgen, W and Reinhold, U (2002). Treosulfan and gemcitabine in metastatic uveal melanoma: First multicenter experience. BLACKWELL PUBLISHING INC.
Brandner, JM, Proksch, E, Von den Driesch, P, Kief, S, Wladykowski, E, Haass, NK and Moll, I (2002). Do tight junctions play a role in the barrier function of the skin?. BLACKWELL PUBLISHING INC.
Brandner, J, Haass, NK, Kief, S, Wladykowski, E, Houdek, P and Moll, I (2001). Expression and localisation of various tight-junction-proteins in the human epidermis and various diseases. BLACKWELL SCIENCE INC.
Haass, NK, Brandner, JM, von den Driesch, P, Kief, S, Wladykowski, E, Houdek, P and Moll, I (2001). Induction of gap junction proteins in epithelial skin tumours and adjacent epidermis. BLACKWELL SCIENCE INC.
Haass, N, Leube, R, Eshkind, L and Moll, I (2001). The essential role of pantophysin in early development of the skin. BLACKWELL SCIENCE INC.
Haass, NK, Leube, RE, Eshkind, LG, Jung, S and Moll, I (2000). The essential role of pantophysin in intracellular transport in human and murine skin, hair follicles and skin tumors. BLACKWELL SCIENCE INC.
Haass, N. K., Kuwert, Ch and Moll, I. (2000). Generalized ichthyosiform exfoliative dermatitis - Induced by a mitomycin instillation therapy of a urothelial carcinoma? Generalisierte ichthyosiforme exfoliative dermatitis - Induziert durch eine mitomycin-instillations-therapie eines urothelkarzinoms?.
Data Collection
Guan, Yimeng, Gunasingh, Gency and Haass, Nikolas (2023). Specific T cells infiltration assay. The University of Queensland. (Dataset) doi: 10.48610/ede5871