Frazer Institute

Dr Michelle Chamoun

Postdoctoral Research Fellow
Frazer Institute
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Researcher biography

Dr Michelle Chamoun joined The Frazer Insitute in 2023 in A/Prof. Timothy Wells' lab and her research broadly encompasses Pseudomonas aeruginosa, antibody-dependant serum resistance, and inflammation. She completed her PhD in 2020 on the role of Interleukin-17 in E. coli chronic urinary tract infection in mice. Michelle left academia in 2020 to work in various industry roles in biotech and pathology with a focus on molecular diagnosis of viral pathogens. Since her return to academia, Michelle has secured a LINC grant to investigate E. coli in blood stream infection, is supervising two students, and has several publications in the pipeline.

Publications

Journal Articles (4)

Journal Articles

Chamoun, Michelle N., Sullivan, Matthew J., Goh, Kelvin G. K., Acharya, Dhruba, Ipe, Deepak S., Katupitiya, Lahiru, Gosling, Dean, Peters, Kate M., Sweet, Matthew J., Sester, David P., Schembri, Mark A. and Ulett, Glen C. (2020). Restriction of chronic Escherichia coli urinary tract infection depends upon T cell-derived interleukin-17, a deficiency of which predisposes to flagella-driven bacterial persistence. FASEB Journal, 34 (11), 14572-14587. doi: 10.1096/fj.202000760R
Acharya, Dhruba, Sullivan, Matthew J., Duell, Benjamin L., Goh, Kelvin G. K., Katupitiya, Lahiru, Gosling, Dean, Chamoun, Michelle N., Kakkanat, Asha, Chattopadhyay, Debasish, Crowley, Michael, Crossman, David K., Schembri, Mark A. and Ulett, Glen C. (2019). Rapid bladder interleukin-10 synthesis in response to uropathogenic Escherichia coli is part of a defense strategy triggered by the major bacterial flagellar filament FliC and contingent on TLR5. mSphere, 4 (6) e00545, e00545-19. doi: 10.1128/msphere.00545-19
Chamoun, Michelle N., Sullivan, Matthew J. and Ulett, Glen C. (2018). Quantification of bacteriuria caused by Hemolysin-positive Escherichia coli in human and mouse urine using quantitative polymerase chain reaction (qPCR) targeting hlyD. Journal of Microbiological Methods, 152, 173-178. doi: 10.1016/j.mimet.2018.08.004
Chamoun, Michelle N., Blumenthal, Antje, Sullivan, Matthew J., Schembri, Mark A. and Ulett, Glen C. (2018). Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection. Critical Reviews in Microbiology, 44 (4), 1-22. doi: 10.1080/1040841X.2018.1426556