Associate Professor Adrian Mattke

Mattke, Adrian C., Johnson, Kerry, Gibbons, Kristen, Le Marsney, Renate, Long, Debbie A., O’Brien, Christopher, Blumenthal, Antje, Venugopal, Prem S., Alphonso, Nelson and Schlapbach, Luregn J. (2026). Sweep Gas Nitric Oxide During Extracorporeal Membrane Oxygenation in Neonates and Children (NECTAR Trial): A Single-Center, Pilot Randomized Controlled Trial. Pediatric Critical Care Medicine, 27 (5), 666-677. doi: 10.1097/PCC.0000000000003926

Mattke, Adrian C., Schlapbach, Luregn J., Takashima, Mari, Johnson, Kerry E., McPherson, Stephen, Venugopal, Prem S. and Blumenthal, Antje (2026). Sweep Flow Nitric Oxide Effects on Coagulation, Inflammation, and Endothelial System Activation During Extracorporeal Membrane Oxygenation. ASAIO Journal 10.1097/MAT.0000000000002709, 1-9. doi: 10.1097/mat.0000000000002709

Mattke, Adrian C., Slaughter, Eugene, Johnson, Kerry, Low, Michelle, Betts, Kim, Gibbons, Kristen S., Le Marsney, Renate and Marathe, Supreet (2025). Conventional cardiopulmonary resuscitation versus extracorporeal membrane oxygenation-assisted CPR in children: a retrospective analysis of outcomes and factors associated with conversion from the former to the latter. Children, 12 (3) 378, 378. doi: 10.3390/children12030378

Shrimpton, Nicole Y. R., Black, Anthony P., Venugopal, Prem S., Alphonso, Nelson and Mattke, Adrian C. (2024). Viability of extracorporeal membrane oxygenation circuits during arterio-venous shunting: an observational study of ECMO circuits. The Open Anesthesia Journal, 18 (1) e25896458296782, 1-8. doi: 10.2174/0125896458296782240930053428

Bowers, Philippa Jane Temple, Daley, Michael, Shrimpton, Nicole Yvette Renee, Mattke, Adrian, Shikata, Fumiaki, Betts, Kim, Black, Anthony, Marathe, Supreet Prakash, Venugopal, Prem and Alphonso, Nelson (2024). Hyperlactataemia following crystalloid cardiopulmonary bypass priming in paediatric cardiac surgery—benign or malignant? A retrospective study. Children, 11 (11) 1379, 1-8. doi: 10.3390/children11111379

Mattke, Adrian C., Alphonso, Nelson, Ren, Chanelle, Jardine, Luke, Johnson, Kerry E., Venugopal, Prem and McBride, Craig A. (2024). Long‐term outcomes and quality of life in congenital diaphragmatic hernia survivors treated with extracorporeal life support: a cross‐sectional survey. Journal of Paediatrics and Child Health, 61 (1), 75-79. doi: 10.1111/jpc.16717

Crawford, Lachlan, Marathe, Supreet P., Betts, Kim S., Karl, Tom R., Mattke, Adrian, Rahiman, Sarfaraz, Campbell, Isobella, Inoue, Takamichi, Patukale, Aditya, Iyengar, Ajay, Konstantinov, Igor E., Venugopal, Prem, Alphonso, Nelson, Andrews, David, Artrip, John, Brink, Johann, Brizard, Christian, Davies, Ben, Finucane, Kirsten, Liava’a, Matt, Nair, Harikrishnan, Nicholson, Ian and ANZCORS Collaborative (2024). Outcomes after hospital discharge in children requiring post-cardiotomy extracorporeal membrane oxygenation: a binational retrospective cohort study. The Journal of Thoracic and Cardiovascular Surgery, 169 (6), 1548-1558.e5. doi: 10.1016/j.jtcvs.2024.11.016

Mattke, Adrian C., Johnson, Kerry E., Ariyawansa, Krishanti, Trnka, Peter, Venugopal, Prem S., Coman, David, Schibler, Andreas and Gibbons, Kristen (2024). Urinary chloride excretion in critical illness and acute kidney injury: a paediatric hypothesis-generating cohort study post cardiopulmonary bypass surgery. Anaesthesia and Intensive Care, 52 (6) 310057X241265119, 1-10. doi: 10.1177/0310057X241265119

Crawford, Lachlan, Marathe, Supreet P., Betts, Kim S., Karl, Tom R., Mattke, Adrian, Rahiman, Sarfaraz, Campbell, Isobella, Inoue, Takamichi, Nair, Harikrishnan, Iyengar, Ajay, Konstantinov, Igor E., Andrews, David, Artrip, John, Brink, Johann, Brizard, Christian, Davies, Ben, Finucane, Kirsten, Johnson, Janelle, Liava’a, Matt, Nicholson, Ian, Patukale, Aditya, Venugopal, Prem, Alphonso, Nelson and ANZCORS Collaborative (2024). Early outcomes after post-cardiotomy extracorporeal membrane oxygenation in paediatric patients: a contemporary, binational cohort study. European Journal of Cardio-Thoracic Surgery, 65 (4) ezae124, 1-9. doi: 10.1093/ejcts/ezae124

Raman, Sainath, Rahiman, Sarfaraz, Kennedy, Melanie, Mattke, Adrian, Venugopal, Prem, McBride, Craig, Tu, Quyen, Zapf, Florian, Kuhlwein, Eva, Woodgate, Jemma, Singh, Puneet, Schlapbach, Luregn J. and Gibbons, Kristen S. (2023). REstrictive versus StandarD FlUid Management in Mechanically Ventilated ChildrEn Admitted to PICU: study protocol for a pilot randomised controlled trial (REDUCE-1). BMJ Open, 13 (11) e076460, 1-8. doi: 10.1136/bmjopen-2023-076460

Plummer, Mark P., Rait, Louise, Finnis, Mark E., French, Craig J., Bates, Samantha, Douglas, James, Bhurani, Mansi, Broadley, Tessa, Trapani, Tony, Deane, Adam M., Udy, Andrew A., Burrell, Aidan J.C., Visser, Adam, Mattke, Adrian, Regli, Adrian, Rashid, Alan, Tabah, Alexis, Walker, Alison, Cheng, Allen, Corley, Amanda, Udy, Andrew, Ramnani, Anil, Eidan, Anthony, DeKeulenaer, Bart, Reddi, Benjamin, Richards, Brent, Knott, Cameron, Moore, Cara, Delzoppo, Carmel ... for the SPRINT-SARI Australia Investigators (2023). Diabetes mellitus, glycaemic control, and severe COVID-19 in the Australian critical care setting: a nested cohort study. Australian Critical Care, 36 (4), 579-585. doi: 10.1016/j.aucc.2022.05.002

Mattke, Adrian, Johnson, Kerry, Gibbons, Kristen, Long, Debbie, Robertson, Jeremy, Venugopal, Prem, Blumenthal, Antje, Schibler, Andreas and Schlapbach, Luregn (2023). Nitric oxide on extracorporeal membrane oxygenation in neonates and children (NECTAR Trial): Protocol for a randomized controlled trial. JMIR Research Protocols, 12 e43760, 1-10. doi: 10.2196/43760

Raman, Sainath, Gibbons, Kristen S., Mattke, Adrian, Schibler, Andreas, Trnka, Peter, Kennedy, Melanie, Le Marsney, Renate and Schlapbach, Luregn J. (2022). Effect of Saline vs gluconate/acetate–buffered solution vs lactate-buffered solution on serum chloride among children in the pediatric Intensive Care Unit: the SPLYT-P randomized clinical trial. JAMA Pediatrics, 177 (2), 122-131. doi: 10.1001/jamapediatrics.2022.4912

Rimpau, Sebastian, Gibbons, Kristen, Venugopal, Prem, Alphonso, Nelson, Anderson, Benjamin, Johnson, Kerry E. and Mattke, Adrian C. (2022). Outcomes after Stage I Norwood palliation in a recently established program can achieve results similar to longer established services. Heart Lung and Circulation, 31 (8), 1176-1181. doi: 10.1016/j.hlc.2022.02.004

Doo, Irene, Staub, Lukas P., Mattke, Adrian, Haisz, Emma, Seidler, Anna Lene, Alphonso, Nelson and Schlapbach, Luregn J. (2022). Diagnostic accuracy of infection markers to diagnose infections in neonates and children receiving extracorporeal membrane oxygenation. Frontiers in Pediatrics, 9 824552, 824552. doi: 10.3389/fped.2021.824552

Fincher, Sophie, Gibbons, Kristen, Johnson, Kerry, Trnka, Peter and Mattke, Adrian C. (2021). Urinary chloride excretion postcardiopulmonary bypass in pediatric patients—a pilot study. Journal of Pediatric Intensive Care, 13 (01), 080-086. doi: 10.1055/s-0041-1736549

Anderson de la Llana, Rebecca, Le Marsney, Renate, Gibbons, Kristen, Anderson, Benjamin, Haisz, Emma, Johnson, Kerry, Black, Anthony, Venugopal, Prem Sundar and Mattke, Adrian Christian (2021). Merging two hospitals: the effects on pediatric extracorporeal cardiopulmonary resuscitation outcomes. Journal of Pediatric Intensive Care, 10 (3), 202-209. doi: 10.1055/s-0040-1715853

Raman, Sainath, Schibler, Andreas, Le Marsney, Renate, Trnka, Peter, Kennedy, Melanie, Mattke, Adrian, Gibbons, Kristen and Schlapbach, Luregn J. (2021). 0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial. Trials, 22 (1) 427. doi: 10.1186/s13063-021-05376-5

Burrell, Aidan J.C., Neto, Ary Serpa, Trapani, Tony, Broadley, Tessa, French, Craig, Udy, Andrew A., Visser, Adam, Mattke, Adrian, Regli, Adrian, Rashid, Alan, Tabah, Alexis, Walker, Alison, Cheng, Allen, Corley, Amanda, Ramnani, Anil, Leditschke, Anne, Eidan, Anthony, DeKeulenaer, Bart, Mevavala, Baumik, Mulholland, Ben, Reddi, Benjamin, Richards, Brent, Knott, Cameron, Moore, Cara, Delzoppo, Carmel, Boschert, Catherine, Tacon, Catherine, Corrigan, Claire, Austin, Danielle ... for the SPRINT-SARI Australia Investigators (2021). Rapid translation of COVID-19 preprint data into critical care practice. American Journal of Respiratory and Critical Care Medicine, 203 (3), 368-371. doi: 10.1164/rccm.202009-3661LE

Mattke, Adrian C., Shikata, Fumiaki, McGill, James, Justo, Rob and Venugopal, Prem (2020). Successful management of a neonate with OTC deficiency presenting with hyperammonemia and severe cardiac dysfunction with extracorporeal membrane oxygenation support and continuous renal replacement therapy. JIMD Reports, 55 (1), 12-14. doi: 10.1002/jmd2.12135

Mattke, Adrian C., Johnson, Kerry E., Parker, Suzanne, Stocker, Christian, Gibbons, Kristen and Schibler, Andreas (2020). Antithrombin dosing guidelines in children underestimate dose needed for plasma level increase. Pediatric Critical Care Medicine, 21 (8), 746-752. doi: 10.1097/PCC.0000000000002383

Lim, Adeline Yi Ling, Mattke, Adrian Christian, Clark, Julia Elizabeth, Pinzon-Charry, Alberto, Alphonso, Nelson and Kapur, Nitin (2020). Acquired immunodeficiency from maternal chemotherapy and severe primary pneumocystis infection in an infant. Case Reports in Pediatrics, 2020 (1), 1-5. doi: 10.1155/2020/5740304

Reddan, Tristan, Venugopal, Prem S., Powell, Jennifer and Mattke, Adrian C. (2020). Ultrasonographic assessment of aortic flow characteristics in a paediatric patient with sepsis treated with extracorporeal life support: defining the mixing zone. Australasian Journal of Ultrasound in Medicine, 23 (4) ajum.12206, 255-263. doi: 10.1002/ajum.12206

Ullman, Amanda J., Long, Debbie, Williams, Tara, Pearson, Kylie, Mihala, Gabor, Mattke, Adrian C., Macfarlane, Fiona and Rickard, Claire M. (2019). Innovation in central venous access device security: a pilot randomized controlled trial in pediatric critical care. Pediatric Critical Care Medicine, 20 (10), e480-e488. doi: 10.1097/PCC.0000000000002059

Mattke, Adrian C., Haisz, Emma, Black, Anthony and Venugopal, Prem (2019). Pump controlled retrograde trial off using the Cardiohelp console: safety considerations. Perfusion, 34 (6), 530-531. doi: 10.1177/0267659119865827

Mattke, Adrian C. and Venugopal, Prem (2019). Prognostic Evaluation of Mortality after Pediatric Resuscitation Assisted by Extracorporeal Life Support. Journal of Pediatric Intensive Care, 8 (3), 191-192. doi: 10.1055/s-0039-1692968

Pandya, Nischal R., Daley, Michael, Mattke, Adrian, Shikata, Fumiaki, Betts, Kim, Haisz, Emma, Black, Anthony, Anderson, Benjamin, Alphonso, Nelson and Venugopal, Prem (2019). A comparison of pump-controlled retrograde trial off to arterio-venous bridging for weaning from venoarterial extracorporeal membrane oxygenation. European Journal of Cardio-Thoracic Surgery, 56 (2), 277-284. doi: 10.1093/ejcts/ezy485

Tyson, Marguerite, Mustafa, Ala, Venugopal, Prem, Whitehead, Ben, Anderson, Ben and Mattke, Adrian Christian (2019). Neonatal Kawasaki syndrome presenting as out of hospital cardiac arrest rescued by extracorporeal cardiopulmonary resuscitation. Perfusion, 35 (1), 026765911984743-88. doi: 10.1177/0267659119847438

Mattke, Adrian C., Black, Anthony and Venugopal, Prem (2019). Pump-controlled retrograde trial off: considerations. Perfusion, 34 (2), 173-173. doi: 10.1177/0267659118806452

Mattke, Christian Adrian, Haisz, Emma, Pandya, Nischal, Black, Anthony and Venugopal, Prem (2017). Creating a Controlled Arterio-Venous Shunt by Reversing the Extracorporeal Membrane Oxygenation Blood Flow: A Strategy for Weaning Patients Off Veno-Arterial Extracorporeal Membrane Oxygenation. Pediatric Critical Care Medicine, 18 (10), 973-976. doi: 10.1097/PCC.0000000000001274

Mattke, Adrian C., Prabhu, Sudesh, Clark, Julia, Labrom, Robert, Burns, Hanna and Schlapbach, Luregn J. (2017). Lemierre's syndrome, necrotizing pneumonia and staphylococcal septic shock treated with extracorporeal life support. Sage Open Medical Case Reports, 5 2050313X17722726, 1-5. doi: 10.1177/2050313X17722726

Prabhu, Sudesh, Mattke, Adrian C., Anderson, Ben, McBride, Craig, Cooke, Lucy, Karl, Tom and Alphonso, Nelson (2016). Repair of congenital diaphragmatic hernia during extracorporeal life support: Experience with six neonates. ANZ Journal of Surgery, 86 (9), 711-716. doi: 10.1111/ans.13466

Prabhu, Sudesh, Fox, Scott, Mattke, Adrian, Armes, Jane E. and Alphonso, Nelson (2016). Extracorporeal life support in multisystem smooth muscle dysfunction syndrome. World Journal for Pediatric and Congenital Heart Surgery, 8 (6), 750-753. doi: 10.1177/2150135116658457

Mattke, Adrian C., Stocker, Christian F., Schibler, Andreas, Alphonso, Nelson, Johnson, Kerry and Karl, Tom R. (2015). A newly established extracorporeal life support assisted cardiopulmonary resuscitation (ECPR) program can achieve intact neurological outcome in 60 % of children. Intensive Care Medicine, 41 (12), 2227-2228. doi: 10.1007/s00134-015-4036-2

Francis, Joshua R., Nourse, Clare, Vaska, Vikram L., Calvert, Sophie, Northill, Judith A., McCall, Brad and Mattke, Adrian C. (2014). Australian bat lyssavirus in a child: The first reported case. Pediatrics, 133 (4), E1063-E1067. doi: 10.1542/peds.2013-1782

Kumar, Gaurav, Mattke, Adrian C., Bowling, Frank, McWhinney, Avis, Alphonso, Nelson and Karl, Tom R. (2014). Resuscitation of a neonate with medium chain acyl-coenzyme a dehydrogenase deficiency using extracorporeal life support. World Journal for Pediatric and Congenital Heart Surgery, 5 (1), 118-120. doi: 10.1177/2150135113501900

Mattke, Adrian C., Bailey, Emily J., Schuck, Andreas, Dantonello, Tobias, Leuschner, Ivo, Klingebiel, Thomas, Treuner, Joern and Koscielniak, Ewa (2009). Does the time-point of relapse influence outcome in pediatric rhabdomyosarcomas?. Pediatric Blood and Cancer, 52 (7), 772-776. doi: 10.1002/pbc.21906

Mattke, Adrian, Johnson, Kerry, McPherson, Stephen, Betts, Kim, Venugopal, Prem, Alphonso, Nelson, Schlapbach, Luregn, Gibbons, Kristen and Blumenthal, Antje (2025). The effect of nitric oxide on inflammation and coagulation in neonates and children supported with extracorporeal membrane oxygenation (ECMO) – outcomes from a prospective randomized trial. 7th Asia-Pacific Extracorporeal Life Support Organization (APELSO) 2025 Joint Meeting with the Chinese Society of Biomedical Engineering (APELSO 2025 Congress), Beijing, China, 10-12 July 2025. Philadelphia, PA United States: Lippincott Williams and Wilkins. doi: 10.1097/MAT.0000000000002582

Mattke, Adrian, Slaughter, Eugene, Low Low, Michelle, LeMarsney, Renate, Johnson, Kerry, Gibbons, Kristen, Rahiman, Sarfaraz and Marathe, Supreet (2025). Extracorporeal membrane oxygenation assisted versus conventional cardiopulmonary resuscitation in children: a retrospective analysis of factors associated with conversion from one to the other. Australian and New Zealand Intensive Care Society/Australian College of Critical Care Nursing Intensive Care Annual Scientific meeting, Christchurch, New Zealand, 9-11 April 2025. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2025.101343

Crawford, L., Marathe, S., Rahiman, S., Mattke, A., Alphonso, N. and Venugopal, P. (2025). Survival and post-discharge morbidity in patients requiring post-cardiotomy extracorporeal membrane oxygenation in Queensland: a retrospective cohort study. ANZSCTS Annual Scientific Meeting, Noosa, QLD Australia, 7-9 November 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2025.02.030

Mattke, Adrian, Mcbride, C., Ren, C., Rahiman, S., Jardine, L., Johnson, K. and Alphonso, N. (2024). Long-term Outcomes And Quality Of Life In Cdh Survivors Treated With Extracorporeal Life Support: A Cross-sectional Survey. 12th World Congress on Pediatric Intensive and Critical Care, Cancun, Mexico, 1-5 June 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0001084952.43121.a9

Perumal, Gopinath, Marathe, Supreet Prakash, Betts, Kim S., Suna, Jessica, Morwood, Jim, Wildschut, Jason, Mattke, Adrian C., Alphonso, Nelson and Venugopal, Prem (2020). Universal implantation of temporary epicardial pacing wires after surgery for congenital heart disease: necessity or luxury?. 32nd Annual Meeting of the European Association for Cardio Thoracic Surgery, Milan, Italy, 18-20 October 2018. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ejcts/ezz285

Cree, Michele, Walsh, Emma, Mattke, Adrian and Haisz, Emma (2018). Paediatric extracorporeal membrane oxygenation-Do they experience acute kidney injury?. ANZIC/ACCCN Intensive Care Annual Scientific Meeting, Adelaide, SA Australia, 11-13 October 2018.

Pandya, N., Shikata, F., Mattke, A., Black, A., Haisz, E., Alphonso, N. and Venugopal, P. (2018). Successful Weaning Off Veno-Arterial Extracorporeal Membrane Oxygenation Using a Novel Technique of Pump-Controlled Retrograde Flow. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, QLD Australia, 2 - 5 August 2018. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.751

Crowe, L., Herbert, A. and Mattke, A. (2013). Is it appropriate to initiate palliative care in a paediatric intensive care unit (PICU). International Society of Advance Care Planning and End of Life Care Conference, Melbourne, VIC Australia, 9-11 May 2013. London, United Kingdom: BMJ Group. doi: 10.1136/bmjspcare-2013-000491.100

Associate Professor Adrian Mattke

Publications

Journal Articles

Conference Papers