Dr Andrew Burke
ATH - Associate Professor
Prince Charles Hospital Northside Clinical Unit
Researcher biography
Dr Andrew Burke currently works with the UQ Centre for Clinical Research, The University of Queensland and is dual specialist in both infectious diseases and thoracic medicine at The Prince Charles Hospital, Brisbane. He has diverse clinical experience in low income countries and regional Australia and holds a Diploma in Tropical Medicine and Hygiene (Liverpool) and a Masters in Public Health from the University of Queensland.
Andrew is a principal investigator on a number of industry lead trials for pulmonary NTM infection. He is an associate investigator on the FORMAT study assessing clinical outcomes in pulmonary Mycobacterium abscessus infection and with Professor Jason Roberts of UQCCR is leading the pharmacokinetic sub-studies in this multi-national trial.
Andrew is on the Australian Therapeutic Guidelines writing groups for both antibiotics and respiratory disease. He is current chair of the steering committee of the Australasian Clinical Tuberculosis network (ACTnet) and is on the Queensland Tuberculosis Expert Advisory Group. He is currently undertaking a PhD in the pharmacokinetics of mycobacterial drugs in people with tuberculosis and cystic fibrosis. As part of his PhD he is exploring the role of therapeutic drug montioring in complex mycobacterial infections and sees great potential for Australian and Asia-Pacific researchers to contribute to mycobacterial research through involvement in PK studies.
Journal Articles
Evans, Ieuan Edward Shepherd, Smith, Daniel, Henderson, Daniel, Riddles, Timothy, Masel, Philip, Moore, Vanessa, Burke, Andrew J., Thomson, Rachel M. and Reid, David W. (2025). Non-tuberculous mycobacterial infection in cystic fibrosis before and after initiation of elexacaftor/tezacaftor/ivacaftor: now is not the time to lower the guard. BMJ Open Respiratory Research, 12 (1) e003204, 1-9. doi: 10.1136/bmjresp-2025-003204
Patterson-Fahy, Kirby, Carter, Robyn, Bell, Scott C., Evans, Ieuan E. S., Burke, Andrew John and Thomson, Rachel M. (2025). In vitro efficacy of sulbactam/durlobactam combined with β-lactam antibiotics in Australian Mycobacterium abscessus isolates. Journal of Antimicrobial Chemotherapy, 81 (1) dkaf441, 1-9. doi: 10.1093/jac/dkaf441
Jong, Tiffany, Baird, Timothy, Barr, Helen Louise, Bell, Scott, Bigirumurame, Theophile, Brady, Kara, Burke, Andrew, Byrnes, Joshua, Caudri, Daan, Clark, Julia E., Coin, Lachlan J.M., Goh, Felicia, Grimwood, Keith, Hicks, Daniel, Jayawardana, Kaushala, Joshi, Sri, Lee, Katherine, Qvist, Tavs, Reid, David, Rice, Megan, Roberts, Jason A., Rogers, Geraint, Shackleton, Claire, Sly, Peter D., Smyth, Alan R., Stevens, Luke, Stockwell, Rebecca, Tarique, Abdullah, Taylor, Steven ... Wainwright, Claire (2025). Finding the optimal regimen for Mycobacteroides abscessus treatment (FORMaT) in people with Mycobacteroides abscessus pulmonary disease: a multicentre, randomised, multi-arm, adaptive platform trial. BMJ Open, 15 (9) e096188, 1-16. doi: 10.1136/bmjopen-2024-096188
Wolie, Zenaw T., Unwin, Sean, Burke, Andrew, Won, Hayoung, Wallis, Steven C., Seaton, R Andrew, Gilchrist, Mark, Roberts, Jason A. and Sime, Fekade B. (2025). Evaluation of the stability of tigecycline in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy. JAC - Antimicrobial Resistance, 7 (3) dlaf074, dlaf074. doi: 10.1093/jacamr/dlaf074
Roberts, Darren M., Liu, Xin, Parker, Suzanne L., Burke, Andrew, Peek, Jenny, Carland, Jane E., Murnion, Bridin, Seah, Vincent, Wallis, Steven C., Sumi, Chandra D., Pandey, Saurabh, Buscher, Hergen, Byrne, Anthony, Sandaradura, Indy, Bowen, David, Holz, Simon, Stewart, Adam G., Hajkowicz, Krispin M. and Roberts, Jason A. (2025). Population pharmacokinetic modelling of remdesivir and its metabolite GS-441524 in hospitalised patients with COVID-19. Clinical Pharmacokinetics, 64 (5) e0022222, 743-756. doi: 10.1007/s40262-025-01496-2
Thomson, Rachel M., Burke, Andrew J., Morgan, Lucy C. and Colin, Andrew A. (2025). A pilot study to assess the effect of intermittent inhaled nitric oxide as treatment of nontuberculous mycobacteria lung infection. Annals of the American Thoracic Society, 22 (7), 1092-1097. doi: 10.1513/annalsats.202407-745rl
Mou, Claire Y., Henderson, Daniel J., Matson, Angela G., Herd, Karen M., Reid, David W., Riddles, Timothy, Johnson, Ellie, McWhinney, Brett, Swenson, Rebecca, Burke, Andrew and Evans, Ieuan E.S. (2025). The complexities of elexacaftor/tezacaftor/ivacaftor therapeutic drug monitoring in a person with cystic fibrosis and Mycobacterium abscessus pulmonary disease. European Clinical Respiratory Journal, 12 (1) 2458341, 1-5. doi: 10.1080/20018525.2025.2458341
Bell, Peter T., Baird, Timothy, Goddard, John, Olagoke, Olusola S., Burke, Andrew, Subedi, Shradha, Davey, Tiana R., Anderson, James, Sarovich, Derek S. and Price, Erin P. (2025). Evaluating the feasibility, sensitivity, and specificity of next-generation molecular methods for pleural infection diagnosis. Microbiology Spectrum, 13 (2), 1-20. doi: 10.1128/spectrum.01960-24
Singh, Sanjay, Gumbo, Tawanda, Wang, Jann-Yuan, Boorgula, Gunavanthi D., Burke, Andrew, Huang, Hung-Ling, McShane, Pamela J., Amaro-Galvez, Rodolfo, Gross, Jane E., Aryal, Santosh, Heysell, Scott K and Srivastava, Shashikant (2024). Imipenem pharmacokinetics/pharmacodynamics in preclinical hollow fiber model, dose-finding in virtual patients, and clinical evidence of efficacy for Mycobacterium abscessus lung disease. The Journal of Infectious Diseases, 231 (6) jiae601, 1-11. doi: 10.1093/infdis/jiae601
Chen, Ricky Hao, Burke, Andrew, Cho, Jin-Gun, Alffenaar, Jan-Willem and Davies Forsman, Lina (2024). New oxazolidinones for tuberculosis: are novel treatments on the horizon?. Pharmaceutics, 16 (6) 818, 818. doi: 10.3390/pharmaceutics16060818
Thomson, Rachel M., Loebinger, Michael R., Burke, Andrew J., Morgan, Lucy C., Waterer, Grant W. and Ganslandt, Cecilia (2024). OPTIMA: an open-label, non-comparative pilot trial of inhaled molgramostim in pulmonary nontuberculous mycobacterial infection. Annals of the American Thoracic Society, 21 (4), 568-576. doi: 10.1513/annalsats.202306-532oc
Subramaniam, Selvaraj, Kanhere, Mrudula, Shephard, Lisa, Burke, Andrew, Saxon, Sarah and Geake, James (2024). A case of severe Mycobacterium thermoresistibile pneumonia. Respirology Case Reports, 12 (3) e01308, 1-6. doi: 10.1002/rcr2.1308
Lu, Lawrence Y., Lee, Hui Min, Burke, Andrew, Li Bassi, Gianluigi, Torres, Antoni, Fraser, John F. and Fanning, Jonathon P. (2024). Prevalence, risk factors, clinical features, and outcome of Influenza-Associated Pulmonary Aspergillosis (IAPA) in critically ill patients: a systematic review and meta-analysis. CHEST, 165 (3), 540-558. doi: 10.1016/j.chest.2023.09.019
Sawka, Alice and Burke, Andrew (2023). Medications and monitoring in treatment of nontuberculous mycobacteria lung disease. Clinics in Chest Medicine, 44 (4), 815-828. doi: 10.1016/j.ccm.2023.06.012
Morpeth, Susan C., Venkatesh, Balasubramanian, Totterdell, James A., McPhee, Grace M., Mahar, Robert K., Jones, Mark, Bandara, Methma, Barina, Lauren A., Basnet, Bhupendra K., Bowen, Asha C., Burke, Andrew J., Cochrane, Belinda, Denholm, Justin T., Dhungana, Ashesh, Dore, Gregory J., Dotel, Ravindra, Duffy, Eamon, Dummer, Jack, Foo, Hong, Gilbey, Timothy L., Hammond, Naomi E., Hudson, Bernard J., Jha, Vivekanand, Jevaji, Purnima R., John, Oommen, Joshi, Rajesh, Kang, Gagandeep, Kaur, Baldeep, Kim, Seungtaek ... Tong, Steven Y.C. (2023). A randomized trial of Nafamostat for Covid-19. NEJM Evidence, 2 (11), EVIDoa2300132-11. doi: 10.1056/evidoa2300132
Burke, Andrew, Carter, Robyn, Tolson, Carla, Congdon, Jacob, Duplancic, Christine, Bursle, Evan, Bell, Scott C., Roberts, Jason A. and Thomson, Rachel (2023). In vitro susceptibility testing of imipenem- relebactam and tedizolid against 102 Mycobacterium abscessus isolates. International Journal of Antimicrobial Agents, 62 (4) 106938, 1-6. doi: 10.1016/j.ijantimicag.2023.106938
Boast, Alison, How, Jeu Ann, Lau, Charis, Sett, Arun, Gilby, Damian, Burke, Andrew, McWhinney, Brett, Wright, Connor, Tramontana, Adrian, Globan, Maria, Denholm, Justin, Graham, Stephen M and Osowicki, Joshua (2023). Pre-XDR congenital tuberculosis in an extremely premature baby. Clinical Infectious Diseases, 78 (1), 149-153. doi: 10.1093/cid/ciad540
Bell, Peter T., Anderson, James, Coulter, Christopher, Dettrick, Andrew J., Burke, Andrew and Baird, Timothy (2023). A mariner's tale: invasive endotracheal Mycobacterium marinum infection. Respirology Case Reports, 11 (10) e01211, 1-5. doi: 10.1002/rcr2.1211
Divithotewala, Chandima, Sweeney, Emma L., Burke, Andrew, Graves, Bianca, Stewart, Adam, Whiley, David, Heney, Claire, Hopkins, Peter M. and Chambers, Daniel C. (2023). Mycoplasma hominis and Ureaplasma urealyticum infections in the immediate post-lung transplant period: A case series and literature review. Transplant Infectious Disease, 25 (3) e14058, 1-7. doi: 10.1111/tid.14058
Burke, Andrew, Thomson, Rachel M., Wainwright, Claire E. and Bell, Scott C. (2023). Nontuberculous Mycobacteria in Cystic Fibrosis in the Era of Cystic Fibrosis Transmembrane Regulator Modulators. Seminars in Respiratory and Critical Care Medicine, 44 (02), 287-296. doi: 10.1055/s-0042-1759883
McQuilten, Zoe K., Venkatesh, Balasubramanian, Jha, Vivekanand, Roberts, Jason, Morpeth, Susan C., Totterdell, James A., McPhee, Grace M., Abraham, John, Bam, Niraj, Bandara, Methma, Bangi, Ashpak K., Barina, Lauren A., Basnet, Bhupendra K., Bhally, Hasan, Bhusal, Khema R., Bogati, Umesh, Bowen, Asha C., Burke, Andrew J., Christopher, Devasahayam J., Chunilal, Sanjeev D., Cochrane, Belinda, Curnow, Jennifer L., Das, Santa Kumar, Dhungana, Ashesh, Di Tanna, Gian Luca, Dotel, Ravindra, DSouza, Hyjel, Dummer, Jack, Dutta, Sourabh ... Tong, Steven Y.C. (2022). Anticoagulation strategies in non–critically ill patients with Covid-19. NEJM Evidence, 2 (2), EVIDoa2200293. doi: 10.1056/evidoa2200293
Fitzgerald, Deirdre B., Sidhu, Calvin, Budgeon, Charley, Tan, Ai Ling, Read, Catherine A., Kwan, Benjamin C. H., Smith, Nicola Ann, Fysh, Edward T., Muruganandan, Sanjeevan, Saghaie, Tajalli, Shrestha, Ranjan, Badiei, Arash, Nguyen, Phan, Burke, Andrew, Goddard, John, Windsor, Morgan, McDonald, Julie, Wright, Gavin, Czarnecka, Kasia, Sivakumar, Parthipan, Yasufuku, Kazuhiro, Feller-Kopman, David J., Maskell, Nick A., Murray, Kevin and Lee, Y. C. Gary (2022). Australasian Malignant PLeural Effusion (AMPLE)-3 trial: study protocol for a multi-centre randomised study comparing indwelling pleural catheter (±talc pleurodesis) versus video-assisted thoracoscopic surgery for management of malignant pleural effusion. Trials, 23 (1) 530, 1-9. doi: 10.1186/s13063-022-06405-7
Reddy, Taryn, Bajwa, Ramey and Burke, Andrew (2022). The IRIS paradox: Imaging findings in a case of PJP-IRIS. Respirology Case Reports, 10 (9) e01014. doi: 10.1002/rcr2.1014
Zhang, Lai-Ying, Anderson, James, Higgins, Niall, Robinson, Jan, Francey, Sonia, Burke, Andrew, Robinson, Gail, Curtin, Deanne and Tay, George (2022). Screening for obstructive sleep apnoea in patients with serious mental illness. Australasian Psychiatry, 30 (5), 615-618. doi: 10.1177/10398562221108632
Burke, A., Alffenaar, J. and Denholm, J. (2022). Evidence of safety for pretomanid and male reproductive health. The International Journal of Tuberculosis and Lung Disease, 26 (6), 473-474. doi: 10.5588/ijtld.22.0092
Burke, Andrew, Smith, Daniel, Coulter, Chris, Bell, Scott C., Thomson, Rachel and Roberts, Jason A. (2021). Clinical pharmacokinetic and pharmacodynamic considerations in the drug treatment of non-tuberculous mycobacteria in cystic fibrosis. Clinical Pharmacokinetics, 60 (9), 1081-1102. doi: 10.1007/s40262-021-01010-4
Denholm, Justin T., Davis, Joshua, Paterson, David, Roberts, Jason, Morpeth, Susan, Snelling, Thomas, Zentner, Dominica, Rees, Megan, O'Sullivan, Matthew, Price, David, Bowen, Asha, Tong, Steven Y. C., Davis, Joshua, Denholm, Justin, Tong, Steven, ASCOT Investigator Group, Rees, Megan, Paterson, David, Price, David, Morpeth, Susan, O'Sullivan, Matthew, Roberts, Jason, Snelling, Thomas, Anderson, Sue, McQuilton, Zoe, Venkatesh, Bala, Hammond, Naomi, Jha, Vivekanend, Burston, Victoria John ... Slow, Sandy (2020). The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial. Trials, 21 (1) 646. doi: 10.1186/s13063-020-04576-9
Fitzgerald, John L., Hay, Karen, Sheridan, Judith, Chadwick, Alex, Burke, Andrew and Haqqani, Haris M. (2020). Late potentials and early repolarisation are associated with serious mental illness and may portend increased arrhythmic risk. Heart, Lung and Circulation, 29 (10), 1476-1483. doi: 10.1016/j.hlc.2020.02.012
Anderson, James, Curtin, Deanne, Higgins, Niall, Mead, Laura, Robinson, Gail and Burke, Andrew (2018). Screening for obstructive sleep apnoea in inpatients with schizophrenia: a feasibility study. Australian and New Zealand Journal of Psychiatry, 52 (9), 898-899. doi: 10.1177/0004867418790028
Burke, Andrew J., Hay, Karen, Chadwick, Alex, Siskind, Dan and Sheridan, Judith (2018). High rates of respiratory symptoms and airway disease in mental health inpatients in a tertiary centre. Internal Medicine Journal, 48 (4), 433-438. doi: 10.1111/imj.13594
Pinzon-Charry, Alberto, Wamsley, Margaret, Clark, Julia, Burke, Andrew, Walpola, Hiranthi, Abrahall, Rebecca and Nourse, Clare (2018). Diagnosis of miliary tuberculosis in an infant in metropolitan Australia: Detection of infection in 19 further family members,four with pulmonary disease. Journal of Paediatrics and Child Health, 54 (1), 80-83. doi: 10.1111/jpc.13706
Burke, Andrew, Graves, Stephen R. and Anstey, Nicholas M. (2015). Fever and rash from Timor: where have you been and when?. Medical Journal of Australia, 203 (8), 338-339.e1. doi: 10.5694/mja15.00936
Piccolo, Francesco, Pitman, Nicholas, Bhatnagar, Rahul, Popowicz, Natalia, Smith, Nicola A., Brockway, Ben, Nickels, Robert, Burke, Andrew J., Wong, Conroy A., McCartney, Ruth, Choo-Kang, Brian, Blyth, Kevin G., Maskell, Nick A. and Lee, Y. C. Gary (2014). Intrapleural tissue plasminogen activator and deoxyribonuclease for pleural infection. An effective and safe alternative to surgery. Annals of the American Thoracic Society, 11 (9), 1419-1425. doi: 10.1513/AnnalsATS.201407-329OC
Baskerville, Catherine A., Hanrahan, Brendan B., Burke, Andrew J., Holwell, Anna J., Remond, Marc G. W. and Maguire, Graeme P. (2012). Infective Endocarditis and Rheumatic Heart Disease in the North of Australia. Heart Lung and Circulation, 21 (1), 36-41. doi: 10.1016/j.hlc.2011.08.010
Conference Papers
Wainwright, C., Hicks, D., Rice, M., Jong, T., Gailer, N., Joshi, S., Wang, X., Burke, A., Thomson, R., Grimwood, K., Bell, S. and Clark, J. (2025). Adverse events related to study drugs in finding the optimal regimen for Mycobacterium abscessus treatment (FORMaT) trial. 48th European Cystic Fibrosis Conference, Milan, Italy, 4-7 June 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jcf.2025.03.118
Wainwright, C., Hicks, D., Rice, M., Jong, T., Joshi, S., Wang, X., Burke, A., Thomson, R., Grimwood, K., Bell, S. and Clark, J. (2025). Prevalence of nausea and vomiting and anti-emetic use in the tinding the optimal regimen for Mycobacterium abscessus treatment (Format) trial. 48th European Cystic Fibrosis Conference, Milan, Italy, 4-7 June 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jcf.2025.03.119
Twining, M., Kang, S., Riddles, T., Evans, I., Burke, A.J. and Thomson, R. (2025). Real-world Experience With Inhaled Liposomal Amikacin Suspension for Treatment of Nontuberculous Mycobacterial Pulmonary Disease. ATS International Conference, San Francisco, CA United States, 16-21 May 2025. New York, NY United States: American Thoracic Society. doi: 10.1164/ajrccm.2025.211.abstracts.a5444
Mattison, Graeme, Keating, Rebecca, McWhinney, Brett, Connors, Shannon, Swenson, Rebecca, Evans, Ieuan, Burke, Andrew and Burr, Lucy (2024). Rifabutin induces Elexacaftor metabolism in Mycobacterium abscessus-related pulmonary disease: A case study. 15th Australasian Cystic Fibrosis Conference, Brisbane, QLD Australia, 2–4 August 2024. Richmond, VIC Australia: John Wiley & Sons.
Ramsay, K., Smith, K., Carter, R., Clayton, M., Burke, A., Wainwright, C., Thomson, R. and Bell, S. (2023). Mycobacterium abscessus: Acquisition and transmission pathways. TSANZSRS 2023 The Australia and New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health and Respiratory Science, Christchurch, New Zealand, 25–28 March 2023. Richmond, VIC Australia: John Wiley and Sons. doi: 10.1111/resp.14459
McQuilten, Zoe, Venkatesh, Balasubramanian, Jha, Vivekanand, Roberts, Jason, Morpeth, Susan, Totterdell, James, McPhee, Grace, Abraham, John, Bam, Niraj, Bandara, Methma, Bangi, Ashpak, Barina, Lauren, Basnet, Bhupendra, Bhally, Hasan, Bhusal, Khemr, Bogati, Umesh, Bowen, Asha, Burke, Andrew, Christopher, Devasahayam, Chunilal, Sanjeev, Cochrane, Belinda, Curnow, Jennifer, Reddy, Varaprasad Babu Dara, Das, Santa, Dhungana, Ashesh, Di Tanna, Gian Luca, Dotel, Ravindra, DSouza, Hyjel, Dummer, Jack ... Tong, Steven Y. C. (2022). Anticoagulation and antiplatelet strategies in non-critically ill patients with Covid-19. 64th Annual Meeting and Exposition of the American Society of Hematology (ASH), New Orleans, LA United States, 10-13 December 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1182/blood-2022-168448
Kudo, M., Johnson, J. and Burke, A. (2018). Low utility of microbiology testing in community acquired pneumonia. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Adelaide, SA, Australia, 23–27 March 2018. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13268
Burke, Andrew, Hay, Karen, Chadwick, Alex and Sheridan, Judith (2017). High Rates of Respiratory Symptoms and Airways Disease in Mental Health Inpatients in a Tertiary Centre. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Canberra, ACT, Australia, 24–28 March 2017. Richmond, Australia: Wiley-Blackwell Publishing.
Hakim, R., Mccarthy, L., Masel, P. J., Bowman, R. V., Burke, A., Bazdar, S., Serginson, J. G. and Yang, I. A. (2013). Personalized care for COPD: the "COPD Snapshot". Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science 2013 Annual Scientific Meetings, Darwin, NT, Australia, 22-27 March 2013. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/resp.12045
Daniels, M. G., Leong, S., Bowman, R. V., Yang, I. A., Masel, P., Fiene, A., Robinson, P., Burke, A., McKeon, J., Ayres, J., Duhig, E., Clarke, B., Tran, K., Godbolt, D., Dettrick, A. and Fong, K. M. (2012). Bronchoscopy and Transthoracic-Needle Aspiration Yield for Histomorpho-Molecular Diagnosis. 4th Australian Lung Cancer Conference, Adelaide Australia, 23-25 August 2012. New York, NY, United States: Elsevier.
Chambers, D. C., Burke, A., Daniels, T. W. V., Yerkovich, S. T. and Hopkins, P. M. A. (2011). Community Acquired Respiratory Viral Infection Is a Risk Factor for Death after Lung Transplantation. 31st Annual Meeting and Scientific Sessions on International-Society-for-Heart-and-Lung-Transplantation, San Diego CA, United States, 13-16 April 2011. New York, NY, United States: Elsevier. doi: 10.1016/j.healun.2011.01.360
Thesis
Burke, Andrew (2026). The Pharmacokinetics & Pharmacodynamics of Antimycobacterial Drugs in People with Cystic Fibrosis and Drug-Resistant Tuberculosis Infection. PhD Thesis, UQ Centre for Clinical Research, The University of Queensland. doi: 10.14264/9518e78